Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06661759Recruiting
Sleep study for children with epilepsy
This trial tests a sleep improvement program using a clinic and a smartwatch-like device for children ages 1.5 to 9 with epilepsy. It aims to help kids sleep better, which may improve their seizure control and quality of life.
TaipeiAges 1.5 years–9 years - NCT06087926Recruiting
TMS for apathy in Parkinson's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.
Chapel Hill, North CarolinaAges 55–80 - NCT07224191Recruiting
Brain wave study during memory tasks
This trial studies brain waves to learn how memory works. It may help people with epilepsy who have special brain implants, or healthy volunteers.
New York, New YorkAges 18–70 - NCT06352632RecruitingPhase 3
Adaptive Stroke Trial Testing New Treatments
This trial is testing different treatments for stroke patients to find which work best. It's designed to adapt over time so new treatments can be added as research progresses.
Sydney, New South WalesAges 18 years+ - NCT03869138Recruiting
Improving physical function after stroke using alternative therapies
This study tests alternative therapies to help improve physical abilities like walking, balance, and arm/leg function after a stroke. It may help if you can follow instructions and safely participate in supervised movement exercises.
Chicago, IllinoisAges 18–90 - NCT07689214Recruiting
Normast for diabetic nerve pain in adults
This study tests an oral medication called Normast to see if it helps adults with diabetic polyneuropathy, a type of nerve damage from diabetes. The trial aims to find out if the drug can reduce symptoms and improve quality of life.
Rome, ItalyAges 18–80 - NCT07213219Recruiting
PET-MRI scan for Parkinson's with sleep behavior disorder
This trial uses a combined PET and MRI scan to study the brain's reward system in people with Parkinson's disease who also have REM sleep behavior disorder (RBD). It aims to understand how the brain changes and may help guide future treatments.
Clermont-FerrandAges 45–80 - NCT06193889RecruitingPhase 2/Phase 3
Car-t cell therapy for generalized myasthenia gravis
This trial tests a new cell therapy (CAR-T cells) for people with generalized myasthenia gravis. It aims to reduce symptoms and improve daily life by targeting and destroying faulty immune cells.
Los Angeles, CaliforniaAges 18–75 - NCT07267052Recruiting
Nerve stimulation at acupoints for pain relief
This trial uses a gentle electrical device on acupuncture points to study how it affects pain signals in the body. Healthy adults can join to help researchers understand a possible drug-free way to manage pain.
Taichung, Beitun, TaiwanAges 20 years+ - NCT03848663Recruiting
Training with visual remapping to help reading with central vision loss
This study tests whether a computer-based visual training method (“remapping”) can help people read better even when they have reduced central vision. You may benefit if your eye condition is stable and your eyes can reliably track the training on an eye-tracker.
Minneapolis, MinnesotaAges 16 years+ - NCT07687316Recruiting
Mental effort during light strength training in older adults
This study looks at how older adults use their mind during light strength training. Volunteers do simple exercises and answer questions about how hard they felt they were working.
Kennesaw, GeorgiaAges 65–85 - NCT06971731RecruitingPhase 3
JNT-517 pill for adults with PKU
This trial tests a new pill called JNT-517 to see if it can lower high blood phenylalanine (Phe) levels in people with PKU. You may be a good fit if you have PKU, are at least 18, and can stick to a steady diet.
Los Angeles, CaliforniaAges 18 years+ - NCT07182357Recruiting
Improving hospice transitions for advanced dementia
This study looks at how to improve the transition to hospice care for people with advanced dementia and their care partners. It will interview care partners and healthcare professionals to design better care management.
New York, New YorkAges 18 years+ - NCT06743490Recruiting
Tracking MG symptoms with smartphone recordings
This study uses your smartphone to record symptoms like slurred speech, hoarseness, arm fatigue, or droopy eyelids, making it easier for doctors to understand and monitor myasthenia gravis. Both people with MG and healthy volunteers can take part.
Leiden, South HollandAges 18 years+ - NCT07687706RecruitingPhase 3
Tegoprazan to prevent stomach problems after stroke
This study tests a stomach-protecting medicine called tegoprazan for people who have had a stroke and are starting antiplatelet therapy. It aims to prevent stomach complications like ulcers or bleeding.
Busan, BusanAges 19 years+ - NCT07109375Recruiting
Long-term study of pegunigalsidase alfa for Fabry disease
This study observes how well the medication pegunigalsidase alfa works over a long period in people with Fabry disease. It helps doctors learn more about managing the condition in everyday life.
ArezzoAges 18 years+ - NCT07220538RecruitingPhase 4
Ginkgo biloba for memory problems after a mild stroke
This trial tests whether adding ginkgo biloba extract tablets to standard stroke care helps improve memory and thinking in people who had a mild stroke. You may join if you are 55 or older, had a mild stroke in the last 1 to 2 weeks, and now have some cognitive difficulties.
AnyangAges 55 years+ - NCT07347574Recruiting
Early Alzheimer's detection study in Hong Kong communities
This study aims to find early signs of Alzheimer's in the community through blood tests and assessments. It's for people who can think clearly and agree to participate without major health issues.
Hong KongAges 60–75 - NCT07381751Recruiting
AI assessment of Parkinson's motor symptoms via video
This study uses artificial intelligence to analyze videos of standard motor tests (MDS-UPDRS Part III) for people with Parkinson's disease. It aims to see if AI can reliably assess your symptoms, which could lead to easier, more accessible monitoring in the future.
Hong KongAges 18–95 - NCT06930781Recruiting
Study of Ponto implants outside of the operating room
This study looks at how well Ponto implants work when placed in a clinic or office setting instead of a hospital operating room. It is for adults who already had this procedure in 2019 or later.
Sacramento, CaliforniaAges 18 years+ - NCT07660913Recruiting
Vibrating therapy for carpal tunnel syndrome
This study tests whether a gentle vibrating therapy (matrix rhythm therapy) can help relieve pain, tingling, and numbness from carpal tunnel syndrome. Participants will receive the therapy, and researchers will track if it improves hand function without surgery or drugs.
IzmirAges 18–60 - NCT07094269Recruiting
Fatigue management program for Parkinson's disease
This trial tests a structured fatigue management program compared to standard information to help people with Parkinson's disease better manage their energy. It aims to improve your confidence in using energy-saving strategies.
GenovaAges 18 years+ - NCT07034794Recruiting
Lysoveta for memory in healthy adults with mild memory concerns
This study tests whether a supplement called Lysoveta can help with memory and thinking in healthy adults who have mild memory problems. You would take the supplement or a placebo daily for several weeks and visit a clinic for memory tests and questionnaires.
London, OntarioAges 50–75 - NCT07656584Recruiting
Helping clinics support patients with communication disabilities
This study looks at how doctors and clinics can better support people with communication disabilities. Researchers will interview patients and staff to find ways to make office visits easier for everyone.
Aurora, ColoradoAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.