Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT07649135Recruiting
Remote Step-Counting Program for Stroke Recovery
This study tests whether a remote (at-home) program that tracks your daily steps and includes support from someone you know can help you become more physically active after a stroke. Researchers want to see if this approach is practical and if it helps people who had a stroke 6+ months ago move more.
Minneapolis, MinnesotaAges 18 years+ - NCT06600815Recruiting
Step-by-step numbing shots for pain relief in knee replacement
This study tests whether a special step-by-step numbing injection given before knee replacement surgery can provide better pain relief during and after the procedure. It may help you have less pain and use fewer painkillers after surgery.
Fuzhou, FujianAges 18 years+ - NCT06600854Recruiting
BoneTape trial for cheekbone and upper jaw fractures
This study tests a new bone tape (BoneTape) for fixing certain types of facial fractures. If you have an unstable break in your cheekbone or upper jaw that needs surgery, this trial may be a good fit.
Toronto, OntarioAges Any age - NCT06601127RecruitingPhase 2
Tiprogrel for recent minor stroke or high-risk TIA
This trial tests a new anti-platelet drug called Tiprogrel to prevent another stroke in people who recently had a minor stroke or a transient ischemic attack (TIA) with certain artery narrowing or plaques. It aims to see if this medicine is safe and works better than current treatments.
Shenyang, LiaoningAges 40 years+ - NCT06601569Recruiting
Movement and balance in children with cerebral palsy
This study looks at children with cerebral palsy to understand what affects their range of motion and balance. The results may help improve physical therapy for kids like them.
Cairo, Cairo GovernorateAges 1.5 years–5 years - NCT06602544Recruiting
Robotic suit to prevent freezing in Parkinson's
This study tests a robotic suit designed to help prevent freezing of gait (a sudden feeling of being stuck) in people with Parkinson's disease. You'll attend 8 visits to see if the suit can improve your walking and reduce falls.
Allston, MassachusettsAges 18–90 - NCT06602479RecruitingPhase 2
Study of MEDI0618 for episodic migraine
This trial tests a new medicine, MEDI0618, against a placebo for people with episodic migraine. The goal is to see if MEDI0618 is safe and effective at reducing migraine days.
Birmingham, AlabamaAges 18–70 - NCT06603792RecruitingEarly Phase 1
Neurofeedback for diabetic nerve pain
This trial tests whether a brain-training technique called neurofeedback can help reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have had moderate-to-severe nerve pain for at least 3 months.
OdenseAges 18–82 - NCT06604000Recruiting
Goal management training for cognitive control after brain injury
This trial tests a training program called Goal Management Training (GMT) to help people who have had a brain injury improve their ability to plan, focus, and stay organized. If you have trouble with these skills and your injury happened at least a year ago, this training might help you get better at everyday tasks.
TrondheimAges 18–65 - NCT06604143Recruiting
Hand and finger recovery after stroke
This study tests whether a hand exercise program can improve movement in people who had a stroke more than 6 months ago. It aims to help you regain control of your hand and fingers.
Toronto, OntarioAges 19–80 - NCT06604117Recruiting
Probucol and statins for recent ischemic stroke
This trial tests whether adding probucol to statin therapy can help people who recently had an ischemic stroke caused by hardened arteries. The goal is to see if this combination works better than statins alone for preventing future strokes.
Xicheng District, Beijing MunicipalityAges 18 years+ - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06604208Recruiting
Improving sleep with binaural beats for insomnia
This study tests if listening to binaural beats (a type of sound therapy) can help improve sleep quality for people with insomnia. If you have trouble sleeping at least 3 nights a week for 3 months or more, this might be a good option for you.
Taoyuan, TaiwanAges 20–75 - NCT06604520RecruitingPhase 2
Vortioxetine for mood and thinking in frontotemporal dementia
This trial tests if vortioxetine, an antidepressant, can improve mood symptoms (like depression or anxiety) and thinking abilities in people with frontotemporal dementia (FTD). It also includes healthy volunteers for comparison.
Baltimore, MarylandAges 45 years+ - NCT06604936Recruiting
Core endurance in fibromyalgia
This study looks at how well people with fibromyalgia can use their core (tummy and lower back) muscles. It may help doctors understand how to improve pain and movement.
ElâzığAges 18–65 - NCT06605014Recruiting
Body alignment after stroke or mini-stroke
This study looks at how a stroke or mini-stroke affects the body's natural movement and alignment (called somatic dysfunction). Researchers want to see if there are common patterns of tightness or imbalance after a stroke, which could help guide future treatments.
Sacramento, CaliforniaAges 18 years+ - NCT06605183Recruiting
Community walking program for Parkinson's disease
This study tests a 6-month community walking program designed for people with Parkinson's disease. It aims to help you stay active and improve your walking ability.
Las Vegas, NevadaAges 30–85 - NCT06605755Recruiting
Testing a pentavalent vaccine in 2-month-old babies
This trial tests a combined vaccine that protects against five diseases (diphtheria, tetanus, whooping cough, polio, and Hib) in 2-month-old babies who have already received 4 doses. It aims to check the vaccine's safety and how well it builds immunity.
Nanjing, JiangsuAges 1.6 years–1.8 years - NCT06606574Recruiting
Baclofen pump for children with cerebral palsy and dystonia
This study tests if a pump that delivers baclofen directly into the spinal fluid can help children with cerebral palsy who have severe dystonia (uncontrolled muscle tightness). It looks at how well the treatment works and tracks progress over time.
Houston, TexasAges Up to 17 years - NCT06607029Recruiting
Painkiller-free anesthesia for brain tumor surgery
This trial tests whether avoiding opioid painkillers during anesthesia for brain tumor removal can be safe and effective. It may help patients recover with fewer side effects.
BeijingAges 18–65 - NCT06607471Recruiting
Study on non-ischemic heart muscle diseases
This study looks at different types of heart muscle diseases that are not caused by blocked arteries (non-ischemic cardiomyopathies). It aims to better understand how to diagnose, predict outcomes, and treat these conditions by gathering information from many patients over time.
Milan, MilanoAges 18 years+ - NCT06607523Recruiting
Prebiotic treatment for brain injury recovery
This study tests whether a prebiotic (a type of fiber that feeds healthy gut bacteria) can improve recovery from a brain injury by helping the connection between the gut and the brain. Participants include people with a recent brain injury and their family members or staff, all of whom are part of the Moody Neurorehabilitation Institute community.
Galveston, TexasAges 18 years+ - NCT06607627RecruitingPhase 3
Testing gefurulimab in children with generalized myasthenia gravis
This study tests a new drug called gefurulimab in children and teens with generalized myasthenia gravis (a disease that causes muscle weakness). It looks at how safe and effective the drug is, and how it works in the body.
Washington D.C., District of ColumbiaAges 6–17 - NCT06607692RecruitingPhase 1/Phase 2
LuPARPed: Targeted radiation plus olaparib for certain childhood cancers
This trial tests a combination of a radioactive drug (Lutathera) and a targeted pill (olaparib) for children and teens whose solid tumors have come back or not responded to treatment and show high levels of a specific receptor (SSTR) on scans. The goal is to see if this two-drug approach can shrink tumors or stop them from growing.
Boadilla del Monte, MadridAges 3 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.