Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06646484Recruiting
Using a device to check hydration after brain bleeding
This study tests a new way to monitor your body's water and sodium levels using a simple, painless device (impedancemetry) after a subarachnoid hemorrhage. It may help doctors better manage your hydration and prevent complications during your ICU stay.
Lyon, FranceAges 18 years+ - NCT06646510Recruiting
Electrical stimulation for resting tremors in Parkinson's
This trial tests whether gentle electrical stimulation to the skin (called sensory electrical stimulation) can help reduce resting tremors in people with Parkinson's disease. Resting tremors are shaking that happens when your muscles are relaxed, like when your hands are in your lap.
GizaAges 45–60 - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06647433Recruiting
Risk in healthcare decisions for consciousness disorders
This study explores how families and healthcare workers think about risk when making decisions for someone in a disorder of consciousness. It aims to understand these perspectives to improve care.
London, LondonAges 18 years+ - NCT06647524RecruitingPhase 2
How cannabis affects the aging brain
This study uses brain scans (fMRI) to see how THC (the active ingredient in cannabis) affects the brain as people age. If you are a cannabis user without current dependence or health issues, you may help researchers understand these effects.
Hartford, ConnecticutAges 18–75 - NCT06647641Recruiting
Genetics study for PSP, CBS, MSA, and related conditions
This study looks at genetic factors in people with PSP, CBS, MSA, or similar brain conditions, and also in their family members. It involves genetic testing to learn more about these diseases and may help find new treatments.
Boston, MassachusettsAges 35 years+ - NCT06648954Recruiting
Brain stimulation to improve hand movement in chronic stroke
This study tests whether a brain stimulation technique called high-definition transcranial direct current stimulation (HD-tDCS) can help improve hand and arm movement in people who had a stroke more than a year ago. The stimulation targets the parts of the brain that control movement, and the goal is to see if it can boost recovery when combined with standard therapy.
Hong KongAges Any age - NCT06649058RecruitingPhase 2
Study on combining drugs and radiation for brain metastases
This trial is for people with cancer that has spread to the brain (brain metastases). It tests a new approach where you start a systemic therapy (drugs that travel through your body) and later add focused radiation to the brain tumors, instead of treating them right away. The goal is to see if this sequence works well and avoids unnecessary side effects.
Houston, TexasAges 18 years+ - NCT06649097Recruiting
Brain clot removal using continuous fluid irrigation
This trial tests a system that continuously bathes the brain with fluid to wash away blood after a brain bleed, which may help recovery.
New York, New YorkAges 18 years+ - NCT06649968Recruiting
Testing a smart glove for hand recovery after stroke
This trial tests a high-tech glove that helps track and improve hand and arm movement after a stroke. It may be an option for people who had a stroke 1 to 6 months ago and have mild to moderate arm weakness.
AcerenzaAges 18 years+ - NCT06650163RecruitingPhase 1
New imaging test for brain tumor surgery planning
This trial tests a new kind of PET scan that uses a special tracer (Zr-89 crefmirlimab berdoxam) to help doctors see brain tumors more clearly before surgery. If you are scheduled to have your brain tumor removed, this scan may give your surgeon extra information to guide the operation.
Los Angeles, CaliforniaAges 18 years+ - NCT06650202Recruiting
Robotic stand trainer and spinal cord stimulation for balance
This trial tests whether combining a robotic stand trainer with spinal cord epidural stimulation can improve balance in people with spinal cord injury. It is for individuals who already have an implanted stimulation unit and cannot stand on their own without it.
West Orange, New JerseyAges 18 years+ - NCT06650319RecruitingEarly Phase 1
Testing LY-M003 injection for Wilson disease
This study tests an injection called LY-M003 for people with Wilson disease who have already been treated with standard medicines. The goal is to see if it is safe and works for them.
Hangzhou, ZhejiangAges 10–60 - NCT06650436Recruiting
Stroke, Delirium, and Long-Term Thinking Changes
This study looks at the link between stroke, delirium (sudden confusion), and long-term thinking problems. It tests whether EEG and MRI scans can help predict who may have trouble thinking clearly after a first stroke.
BrusselsAges 18 years+ - NCT06650527Recruiting
Empathy training for dementia caregivers
This study tests a cognitive empathy training program for people caring for a family member with dementia. The training is designed to help caregivers better understand their loved one's perspective and reduce stress. You may benefit if you live with the person you care for and feel burdened by your caregiving role.
Atlanta, GeorgiaAges 50 years+ - NCT06650631Recruiting
Heat treatment for knee pain from arthritis
This study tests if a heat treatment device can help reduce knee pain caused by arthritis. It involves people with moderate pain who can walk without help and have a recent knee X-ray.
Gravesano, SwitzerlandAges 19–69 - NCT06650969Recruiting
Early detection of cognitive decline in type 2 diabetes
This study is looking at ways to catch early thinking and memory changes in people with type 2 diabetes. By joining, you may help doctors learn how to spot problems sooner and find better ways to help.
Nanjing, JiangsuAges 45 years+ - NCT06651775Recruiting
High-Intensity Laser Therapy for Chronic Leg Pain from Herniated Disc
This study tests whether a type of high-intensity laser therapy (HILT) can help relieve leg pain caused by a herniated disc in the lower back. It is for people who have not had recent back treatments or surgery.
Ankara, CankayaAges 18–65 - NCT06652581Recruiting
Testing a nerve block for gallbladder surgery pain
This study tests a special nerve block called M-TAPA to see if it helps control pain during and after gallbladder removal surgery. It might offer better pain relief with fewer side effects.
Denpasar, BaliAges 18–65 - NCT06652724Recruiting
Psychological help for chronic pain in fibromyalgia and migraine
This study looks at how psychological factors and treatments might help with chronic pain in people with fibromyalgia and/or chronic migraine. It compares different groups to understand what works best.
Rome, RMAges 18–50 - NCT06653348RecruitingPhase 2/Phase 3
Ticagrelor-based therapy for recent mild stroke or high-risk TIA
This trial tests whether switching to a simpler antiplatelet medication (ticagrelor) after a mild stroke or high-risk TIA can prevent another stroke while reducing the risk of bleeding. It is for people who have not received clot-busting treatment or had a large stroke.
Sari, MazandaranAges 40 years+ - NCT06653387Recruiting
Testing a new carotid stent with blood-flow reversal for high-risk patients
This trial tests a new carotid stent system used with a special blood-flow reversal device to treat blocked carotid arteries. It is for people with high-risk conditions who might not be good candidates for traditional open surgery, and aims to see if the stent is safe and effective in preventing strokes.
Sacramento, CaliforniaAges 18–79 - NCT06653400RecruitingPhase 1
Pain relief medicine for office hysteroscopy
This study tests if adding ketorolac (a pain reliever) to lidocaine (a numbing medicine) can reduce pain during a hysteroscopy. If you are scheduled for this procedure, you may be able to join.
New York, New YorkAges 18 years+ - NCT06653543Recruiting
Mulligan technique for neck-related arm pain
This trial tests whether a gentle hands-on method called the Mulligan technique can reduce pain and improve function in people whose arm pain comes from a pinched nerve in the neck. If you have burning or tingling down one arm into your hand, you may be able to join.
Kafr El-Sheikh Governorate, Kafr el-Sheikh GovernorateAges 20–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.