Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06639360Recruiting
Magnetic stimulation after clot removal for stroke recovery
This trial tests whether adding magnetic brain stimulation (TMS) after clot-removal surgery can help people recover better from a stroke. It is for people who had a moderate-to-severe stroke in the front part of the brain and had the clot removed.
Xi'an, ShaanxiAges 18–80 - NCT06640101Recruiting
Breathing muscle training for stroke recovery
This trial tests whether a simple breathing exercise device can help people recovering from stroke. You may benefit if you had a stroke up to 12 months ago and can walk a short distance on your own.
Shenzhen, None SelectedAges 40–80 - NCT06640582RecruitingPhase 1/Phase 2
TIL therapy with pembrolizumab for advanced brain cancer
This trial tests a new treatment for advanced brain cancers like glioma and meningioma. It combines your own immune cells (tumor-infiltrating lymphocytes or TILs) with an immunotherapy drug (pembrolizumab) to help your body fight the tumor. It's for people who have tried other treatments without success or have no standard options left.
Beijing, Beijing MunicipalityAges 16–90 - NCT06640660Recruiting
Study of vision, thinking, and emotions in MS and West Nile
This study looks at how multiple sclerosis or West Nile virus affects visual thinking and mood, and whether a rehab program might help. If you have one of these conditions and can see and use your hands, you may be able to join.
Lido, VeneziaAges 20–85 - NCT06640673Recruiting
Brain Wave Study for Mild Memory Problems and Parkinson's Disease
This study uses a special brain wave test (high-density EEG) to learn more about mild memory problems and how they might be linked to Parkinson's disease. If you join, you'll help researchers understand brain activity patterns that could lead to better diagnosis and care.
Lido, ItalyAges 50–90 - NCT06640894Recruiting
Power2Walk: strength training for kids with cerebral palsy
This study tests a type of strength training called functional power training for children with cerebral palsy. The goal is to see if it helps kids be more active and take part in daily activities.
Emmen, DrentheAges 4–12 - NCT06641336Recruiting
Perceptions of a mixed reality system for stroke recovery
This study tests a new mixed reality (like virtual reality) system called RehAtt to see if it can help people recover arm and hand movement after a first stroke. It is for people who have weakness on one side and can understand instructions.
LjubljanaAges 18 years+ - NCT06641726Recruiting
Global database linking genetics and health records for mental illness
This trial is building a research database that combines genetic information and long-term health data to improve personalized treatment for serious mental illness. You may be eligible if you have been diagnosed or treated for depression, bipolar disorder, schizophrenia, or dementia.
Oxford, OxfordAges 18–110 - NCT06641895RecruitingEarly Phase 1
Testing BBM-D101 gene therapy for Duchenne muscular dystrophy
This early-phase study tests a new gene therapy called BBM-D101 for boys with Duchenne muscular dystrophy (DMD). The goal is to see if it is safe and helps improve muscle function in young boys.
Shanghai, Shanghai MunicipalityAges 4–8 - NCT06641999Recruiting
Tinnitus implant study for adults with chronic tinnitus and hearing loss
This trial tests if a special implant can reduce tinnitus loudness in adults who have had chronic tinnitus for at least 6 months and have some hearing loss. You may qualify if your tinnitus is severe and not helped by standard treatments like hearing aids or therapy.
Edegem, BelgiumAges 18 years+ - NCT06642129Recruiting
Study on spinal fluid pressure management in shunt surgery
This study watches how the pressure of spinal fluid around the brain and spine changes during surgery for communicating hydrocephalus. It aims to help doctors better manage a shunt that drains extra fluid from the lower back to the belly.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06642896Recruiting
Pupil check after medicine for brain swelling in children
This study checks how children’s pupils react after they receive a medicine to lower brain pressure. It aims to see if a quick pupil test can help doctors know if the medicine is working.
Grenoble, ISEREAges 1 month–17 years - NCT06643000Recruiting
High-dose furmonertinib combo for EGFR lung cancer with brain lining spread
This trial tests a strong dose of furmonertinib (a targeted pill) combined with two other drugs, bevacizumab and pemetrexed, for people with EGFR-mutated non-small cell lung cancer that has spread to the lining of the brain or spinal cord. It aims to see if this combination can better control the cancer and improve symptoms.
Zhengzhou, HenanAges 18 years+ - NCT06643013Recruiting
Targeting brain blood vessels to help small vessel disease
This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.
LondonAges 60–90 - NCT06643273Recruiting
Glove to measure touch feeling after stroke
This study tests a special glove that helps measure how well you can feel touch after a stroke. It's for people who had a single stroke within the last 6 months and have some thinking and memory ability.
Florence, ItalyAges 18–85 - NCT06643312Recruiting
Treadmill training with spinal stimulation for standing after spinal cord injury
This trial tests whether combining treadmill training with spinal cord stimulation (TPAD) can help people with severe spinal cord injuries regain the ability to stand. It aims to improve standing function and may lead to better recovery.
West Orange, New JerseyAges 18 years+ - NCT06643598Recruiting
Virtual and lived-experience support for newborns with brain challenges
This study tests whether a program that combines virtual support and a peer who has been through it can help parents of newborns with certain brain conditions. It is designed for families living in rural areas and aims to improve children's recovery.
Madison, WisconsinAges Up to 5 years - NCT06643702Recruiting
Dizziness and balance in older adults
This study is looking at whether dizziness and balance problems in older adults are caused by BPPV (tiny crystals in the inner ear). If you qualify, you may be diagnosed with simple head movements.
Saltsjö-Boo, Stockholm CountyAges 65 years+ - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+ - NCT06644807Recruiting
Neuromodulation for phantom limb pain after amputation
This trial tests a new approach to suppress phantom limb pain using neuromodulation methods. It may help people who have had a limb amputated and continue to experience persistent pain.
Moscow, MoscowAges 18–65 - NCT06645054Recruiting
Testing a smart hallway system in clinics
This trial tests a smart hallway system that may help monitor walking. It is for people who can walk a short distance on their own, have no major memory or thinking problems, and speak Slovenian.
LjubljanaAges 18 years+ - NCT06645405Recruiting
AI scan reading for stroke caused by large vessel blockage
This trial tests whether an AI program can better read CT scans to find large blood vessel blockages that cause stroke. If you had a stroke from a blocked large vessel and already had CT scans, the AI may help doctors decide on treatment faster.
Shanghai, Shanghai MunicipalityAges 18–95 - NCT06645626Recruiting
Health service use and quality of life in atypical Parkinson's
This study looks at how people with certain rare brain conditions (like progressive supranuclear palsy, corticobasal syndrome, or multiple system atrophy) use healthcare services and how their quality of life is affected. It may help doctors better support patients and their carers.
Southampton, HampshireAges 18 years+ - NCT06646250Recruiting
New ultrasound for steady brain monitoring in newborns
This trial uses a new ultrasound device (NeoDoppler) to watch blood flow in a baby's brain continuously. It aims to see if this gentle, bedside tool can help doctors monitor babies—especially those born early or with certain health concerns—without moving them.
TrondheimAges birth–1 year
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.