Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06666764RecruitingPhase 3
Oxygen therapy for stroke patients transferred for clot removal
This trial tests whether giving high-concentration oxygen (normobaric oxygen) during transfer to a hospital that can remove a blood clot can help people with acute ischemic stroke. It is for patients who are being transferred specifically for endovascular therapy (EVT) to remove a large clot in the brain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06666777Recruiting
Speech therapy and parenting for early communication skills
This study tests a program that combines speech therapy with parenting support to help young children with developmental delays improve their communication and social skills. It is designed for children aged 6 months to 5 years who have developmental challenges, and their parents.
Como, ComoAges 6 months–4.9 years - NCT06666816Recruiting
Watching changes in walking for muscle and nerve diseases
This study watches how people with certain muscle or nerve diseases walk over time. It may help doctors understand changes in walking patterns and is open to adults who can walk and have a genetic diagnosis of a neuromuscular condition.
Bosisio Parini, LeccoAges 18–75 - NCT06667141RecruitingPhase 1
Study of ACR-2316 for advanced solid tumors
This study tests a new targeted drug called ACR-2316 for people with specific advanced solid tumors that have already been treated but are no longer responding. It aims to see how well the drug works and how safe it is, while looking for a tumor that has certain markers (like a protein or genetic change) that may make the drug more effective.
Phoenix, ArizonaAges 18 years+ - NCT06667232Recruiting
Burst stimulation for epilepsy using implanted electrodes
This trial tests a new way to stimulate the brain using bursts of electrical pulses in people with drug-resistant epilepsy. It might help find better treatment options for those who are already undergoing SEEG monitoring as part of their presurgical evaluation.
Beijing, Beijing MunicipalityAges 14–65 - NCT06667726RecruitingPhase 2
New PET scan for better brain tumor care
This trial studies a special PET scan called 18F-DOPA PET/CT to see if it can help doctors better manage brain tumors. It may be used before surgery, for radiation planning, or when MRI results are unclear.
Rochester, MinnesotaAges 18 years+ - NCT06667869Recruiting
New monitoring system for sedation in the ICU
This trial tests a new system to monitor sedation in ICU patients who need a breathing tube and sedation for more than a day. It aims to improve care for patients on ventilators.
Santiago, Metropolitana de SantiagoAges 18 years+ - NCT06668519Recruiting
brain wave study in children with seizures and other conditions
This study uses a special brain scan (magnetoencephalography, or MEG) to look at brain activity in children with conditions like seizures, brain tumors, autism, and others. It may help doctors learn more about how these conditions affect the brain.
ShanghaiAges 1 month–18 years - NCT06668597Recruiting
Sleep apnea education and motivation program
This trial tests an educational program to help people with sleep apnea start using CPAP at home. The program is designed to motivate and guide you through the process of adapting to CPAP therapy.
Milan, MilanAges 18 years+ - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT06668623Recruiting
Reiki for nerve pain and sleep in diabetic neuropathy
This trial tests if Reiki, a gentle hands-on energy therapy, can reduce nerve pain and improve sleep in people with diabetic neuropathy. It may offer a non-drug option for managing symptoms.
Kayseri, KocasinanAges 18–70 - NCT06668649Recruiting
Polish fatigue scale study for MS, ALS, or stroke
This study tests a Polish version of a scale that measures how tired people feel. It's for people with MS, ALS, or stroke, or healthy volunteers.
Krakow, Lesser Poland VoivodeshipAges 18 years+ - NCT06669182Recruiting
Cerebellar TMS for Alzheimer's Disease
This trial uses a non-invasive brain stimulation technique (TMS) to target the cerebellum in people with Alzheimer's disease. It aims to see if this treatment can improve symptoms and cognitive function.
Xi'an, ShaanxiAges 50–85 - NCT06669416Recruiting
A study on taste changes during chemotherapy
This study looks at how taste may change when you start chemotherapy for cancer. It aims to help doctors better understand and support patients through these changes.
Chicago, IllinoisAges 18 years+ - NCT06669507Recruiting
Sleep clinic study on non-drug treatment options
This study looks at how people with certain sleep disorders respond to non-medication treatments. If you have trouble with your sleep-wake cycle and would like behavioral or lifestyle help instead of drugs, this trial might be for you.
TrondheimAges 18 years+ - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85 - NCT06669949Recruiting
Studying the natural history of SPLIS disease
This study collects health information from people with SPLIS to better understand the condition over time. It may include your siblings if they also have SPLIS, and data from patients who have passed away.
San Francisco, CaliforniaAges Any age - NCT06670053Recruiting
Testosterone and brain development in teens
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
Aurora, ColoradoAges 12–20 - NCT06670456Recruiting
Brain Bleed Study (Without Surgery)
This study is for people who had a spontaneous brain bleed and did not have surgery. It aims to learn more about their recovery and health over time.
Fuzhou, FujianAges 18 years+ - NCT06670781Recruiting
Comparing two ways to do the Valsalva maneuver during a heart ultrasound
This trial compares two ways of doing a breathing maneuver (Valsalva) during a heart ultrasound to see if it better detects a common hole in the heart (PFO). If you are already scheduled for this test, the study will help find the best method for you.
Ottawa, OntarioAges 18 years+ - NCT06671236RecruitingPhase 1
Treg cell therapy for ALS
This trial tests a new type of cell therapy called regulatory T cells (Tregs) for people with neurodegenerative diseases like ALS. The goal is to see if these cells can slow down the disease.
Zhengzhou, HenanAges 18–70 - NCT06671457Recruiting
Brain stimulation study for insomnia
This trial tests a personalized, non-invasive brain stimulation method (transcranial direct current stimulation, or tDCS) to improve sleep in adults with insomnia. It may help if you have trouble sleeping and haven't tried certain other treatments.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06672107Recruiting
Driving simulator training after stroke
This study tests if using a driving simulator can help improve driving skills in veterans who have had a stroke. If you are a veteran who had a stroke at least 3 months ago and are between 40 and 80 years old, this program might help you get back behind the wheel safely.
Sacramento, CaliforniaAges 40–80 - NCT06672237RecruitingPhase 3
Study of NTLA-2001 for hereditary ATTR amyloidosis with nerve damage
This study is testing a new gene-silencing treatment called NTLA-2001 for people with hereditary ATTR amyloidosis that causes nerve damage. It works by stopping the body from making a faulty protein that builds up and harms nerves.
Buenos AiresAges 18–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.