Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06820125Recruiting
Combined cognitive and motor rehab for MS
This trial compares cognitive rehab alone versus cognitive plus motor rehab using high-tech tools for people with multiple sclerosis who have mild thinking problems and some walking difficulty. It aims to see if adding movement exercises improves outcomes more than cognitive training alone.
Verona, veronaAges 18 years+ - NCT06821230Recruiting
Mindfulness for Parkinson's patients and their caregivers
This study tests whether a dyadic mindfulness program can help both people with Parkinson's disease and their caregivers manage negative emotions. You and your care partner would attend sessions together to learn mindfulness techniques.
Hong KongAges 18 years+ - NCT06821568Recruiting
Home brain stimulation for memory and walking concerns
This study tests if a gentle brain-stimulation device used at home can help older adults who have both memory worries and slower walking. A study partner will help you use the device.
Roslindale, MassachusettsAges 65–90 - NCT06821802Recruiting
Protein supplement for low sodium from SIAD
This trial tests if a protein supplement can help patients with low sodium caused by a condition called SIAD. If you have SIAD and low sodium, you may be able to join.
BaselAges 18 years+ - NCT06821906RecruitingPhase 2
Stereotactic radiosurgery for essential tremor
This trial tests a precise type of radiation therapy (stereotactic radiosurgery) to treat essential tremor when medications don't work well enough. It aims to reduce shaking without the need for brain surgery.
GliwiceAges 50 years+ - NCT06822231Recruiting
High-tech rehab for acute neuromuscular diseases
This study tests a high-tech rehab program using robots and advanced tools to help people recover from acute neuromuscular diseases. It aims to see if this approach improves leg strength and mobility better than standard care.
BariAges 18–80 - NCT06823193Recruiting
How self-processing impacts mental time travel
This study explores how thinking about yourself affects your ability to imagine past or future events. It may help researchers understand how the brain connects self-awareness to memory and planning.
Castel Goffredo, MantovaAges 40–80 - NCT06823466Recruiting
Stroke study for patients on blood thinners
This study looks at people who had a stroke while taking blood thinners (anticoagulants) for an irregular heartbeat. It aims to learn more about these strokes and how to better prevent them in the future.
ZagrebAges 18 years+ - NCT06823752RecruitingPhase 2
Insomnia medication to reduce brain damage markers in adults
This trial tests whether a medication that blocks brain chemicals involved in wakefulness can help reduce markers of nerve damage in people with insomnia. It is for adults aged 40–65 with chronic insomnia, and it aims to see if improving sleep may protect brain health.
Macquarie Park, New South WalesAges 40–65 - NCT06824025RecruitingEarly Phase 1
Comparing two drugs for headache after spinal anesthesia in C-section
This trial tests if a combination of neostigmine and atropine works better than lidocaine for treating severe headaches that can happen after spinal anesthesia during a planned C-section. It aims to find a more effective way to relieve this type of headache.
MinyaAges 18–35 - NCT06824142Recruiting
Testing a 3D clock for Alzheimer's time orientation
This study tests a 3D tool (like a special clock) to help people with Alzheimer's keep track of time. You may be eligible if you have mild to moderate Alzheimer's and trouble with time orientation.
ChampcueilAges 65 years+ - NCT06825403Recruiting
Olfactory training for mild cognitive impairment
This trial tests whether daily scent training can help improve memory and thinking in people with mild cognitive impairment (MCI), a condition that is more than normal aging but not dementia. You would smell different odors at home and track your progress.
New York, New YorkAges 55–89 - NCT06825520Recruiting
Studying urges before tics during habit reversal training
This study tests whether a therapy called 'habit reversal training' can help reduce the strong urges that happen before tics. It is for children and teens (ages 8–17) who have at least 3 tics and feel a warning urge before each tic.
Salt Lake City, UtahAges 8–17 - NCT06825650Recruiting
Turkish adaptation of a pain questionnaire
This study aims to adapt a questionnaire about pain into Turkish and check if it works well. Researchers want to see if the questions are understandable and reliable for people with certain types of pain.
Ankara, AltındağAges 18 years+ - NCT06825897Recruiting
Direct to angiography suite for stroke clot removal
This trial compares two ways to treat severe stroke patients with a large vessel blockage. One way is the standard approach of first imaging you and then deciding. The other way takes you directly to the angiography suite for immediate clot removal by the doctor. The goal is to see if this faster, direct approach helps you get better results.
Iowa City, IowaAges 18 years+ - NCT06826287Recruiting
7T MRI study of action watching in cerebral palsy
This study uses a very powerful 7T MRI scanner to look at how your brain responds when you watch actions. It may help doctors understand brain injury in people with cerebral palsy.
Calambrone, PISAAges 11–40 - NCT06826612RecruitingPhase 1/Phase 2
Gene therapy trial for early Huntington's disease
This trial tests a gene therapy called SPK-10001 for people with early-stage Huntington's disease. It aims to slow the progression of symptoms by targeting the genetic cause of the disease.
Boston, MassachusettsAges 25–65 - NCT06826638Recruiting
Brain activity during arm exercises for MS and healthy volunteers
This study looks at brain activity during task-oriented arm exercises to understand how neurorehabilitation works. It may help people with multiple sclerosis (MS) and healthy volunteers improve motor function.
GenovaAges 18–60 - NCT06826963Recruiting
Eccentric exercise for older adults with heart failure and muscle loss
This study tests whether a special type of exercise (eccentric, or lengthening, exercises) can help older adults with heart failure who also have muscle loss. It aims to see if the exercise is safe and improves strength and function.
Verona, VeronaAges 65–85 - NCT06827301Recruiting
Vagus nerve stimulation for swallowing problems after stroke
This trial tests a non-invasive device that stimulates a nerve in the ear to help improve swallowing after a recent stroke. It may be an option if you have moderate swallowing difficulties diagnosed within the first week after your stroke.
Roma, RMAges 18 years+ - NCT06827678Recruiting
Study of Alzheimer’s disease using brain scans in China
This study uses brain imaging to understand early changes in Alzheimer's disease. It may help people with or without memory problems learn more about their condition and support future treatments.
ShanghaiAges 45–90 - NCT06827834Recruiting
Spinal cord monitoring for multiple sclerosis
This trial uses MRI scans to monitor spinal cord changes in people newly diagnosed with relapsing-remitting MS who have not yet started treatment. It aims to better understand how the disease progresses and could help guide early treatment decisions.
Arnhem, GelderlandAges 18–65 - NCT06827951Recruiting
Parent-child therapy for young kids with behavior issues
This study tests if a therapy called Parent-Child Interaction Therapy (PCIT) helps parents of young children with behavioral concerns. You and your child would attend sessions together to improve your relationship and manage behaviors.
Gainesville, FloridaAges 18–89 - NCT06832514RecruitingPhase 4
Gender and immune response to meningitis B vaccine
This study tests how well the meningitis B vaccine works in transgender and cisgender people. It aims to understand if sex and gender affect immune responses.
GhentAges 18–50
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.