Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06839118RecruitingPhase 3
Botox for headaches after head injury
This trial tests if Botox injections can reduce headache days in people with persistent headaches after a mild head injury. It may help if you have headaches at least 15 days a month.
Glostrup MunicipalityAges 18–80 - NCT06839300Recruiting
Blood biomarkers in spinal cord injury study
This study is looking for people with a spinal cord injury from a blunt force (not a penetrating injury like a gunshot or stab wound) to see if certain substances in the blood (called biomarkers) can help doctors understand the injury better and predict recovery. It involves an initial blood sample within 24 hours of the injury and follow-up assessments.
Milwaukee, WisconsinAges 19 years+ - NCT06839469Recruiting
Walking study for rare muscle and nerve conditions
This study looks at how children and teens with Duchenne muscular dystrophy (DMD) or spinal muscular atrophy (SMA) walk, by having them do walking tests while wearing sensors. The goal is to find better ways to track how these diseases progress and how treatments work over time, without needing blood tests or scans.
Palo Alto, CaliforniaAges 5 years+ - NCT06839482Recruiting
Robot-assisted arm therapy after recent stroke
This study tests whether a robot-assisted therapy program can help people recover arm and hand movement after a recent stroke. If you had a stroke less than 3 months ago and have some weakness in your arm but can still move it a little, this trial may help you regain function.
Elkins Park, PennsylvaniaAges 18–85 - NCT06840405Recruiting
Brain activity during walking after stroke
This study looks at how the brain works while walking in people who have had a stroke. It may help researchers understand walking problems better.
TaipeiAges 20–80 - NCT06840496RecruitingPhase 3
Study of oral NA-921 vs placebo for girls and women with Rett syndrome
This trial tests an oral medication called NA-921 in females with Rett syndrome to see if it works better than a placebo. It may be an option for those who have a confirmed MECP2 gene mutation and stable seizure patterns.
Phoenix, ArizonaAges 5–20 - NCT06840587Recruiting
Connect-Home: Alzheimer's and related dementias study
This trial tests a program to help people with dementia and their caregivers prepare for a safe move from a skilled nursing facility to home or another care setting. It aims to improve the transition and support both the patient and caregiver.
Chapel Hill, North CarolinaAges 19 years+ - NCT06840886RecruitingPhase 1
Testing a new drug for advanced solid tumors
This study tests an experimental drug called PHST001 for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it is safe and if it can help shrink tumors.
Beverly Hills, CaliforniaAges 18 years+ - NCT06840899RecruitingPhase 2
CBD for bladder control after spinal cord injury
This study tests whether CBD can help people with spinal cord injury who have bladder leaks. If you have at least two leaks a day and your injury is above the lower back, you may be able to join.
Madison, WisconsinAges 18 years+ - NCT06841575Recruiting
Better eye imaging for children and adults at Duke
This study tests a new camera that automatically adjusts to take clear pictures of the back of the eye. It aims to improve retinal imaging for healthy adults, adult eye clinic patients, and children seen at Duke Eye Center.
Durham, North CarolinaAges 1 month+ - NCT06841770RecruitingPhase 1
Testing a delivery device for spinal cord injury treatment
This trial tests a device that delivers a special cell therapy (LCTOPC1) into the spinal cord. It is for people with a recent or chronic spinal cord injury that is severe (no feeling or movement below the injury) or leaves some sensation but no movement.
Downey, CaliforniaAges 18–65 - NCT06841848Recruiting
Eye camera test for early Alzheimer's
This study is testing a new eye camera to see if it can help find early signs of Alzheimer's disease. It is for people aged 55 and older who either have mild to moderate Alzheimer's or do not have Alzheimer's.
Rome, ItalyAges 55 years+ - NCT06842095Recruiting
Stimulation therapy for stroke recovery
This trial tests if a non-invasive brain stimulation technique can improve arm movement recovery after a stroke. It is for people who had a stroke affecting their arm and are at least 3 months past the stroke.
OxfordAges 18 years+ - NCT06842329Recruiting
Can distraction ease injection pain for teens with period pain?
This study tests whether using simple distraction techniques during a shot can reduce pain in teenage girls who come to the emergency room with severe menstrual cramps.
SamsunAges 12–18 - NCT06842745RecruitingPhase 2
Brain stimulation plus language therapy for mild aphasia
This study tests whether combining brain stimulation (TMS) with language therapy can help people with mild aphasia after a stroke. It aims to improve speaking and understanding.
Philadelphia, PennsylvaniaAges 40–85 - NCT06842797Recruiting
Do weighted blankets improve sleep quality?
This study tests whether a weighted blanket can help healthy people sleep better. If you're a healthy adult, you may be able to join and use a weighted blanket at home.
Trikala, ThessalyAges 18–45 - NCT06843252Recruiting
Home-based brain stimulation for Huntington's disease symptoms
This study tests whether a gentle brain stimulation device (tDCS) used at home can help improve thinking and behavior in people with Huntington's disease. A caregiver is needed to be present during treatment and help with questionnaires.
San Antonio, TexasAges 18–85 - NCT06843590RecruitingPhase 2
Study of ALKS 2680 for Idiopathic Hypersomnia
This trial tests a new medicine called ALKS 2680 for people with Idiopathic Hypersomnia (a condition that causes extreme sleepiness without a clear cause). The goal is to see if it is safe and effective at helping you stay awake during the day.
Cullman, AlabamaAges 18–70 - NCT06843616Recruiting
Study of a disposable brain clot removal scope for bleeding stroke
This study tests a new disposable tube with a camera (endoscope) that doctors use to remove a blood clot from the brain after a bleeding stroke. It is designed for people who are stable enough for surgery and whose bleed is in a part of the brain that is reachable with this tool.
Guiyang, GuizhouAges 18–80 - NCT06844071Recruiting
Safety of Sentio bone conduction implant in teens
This study tests the safety and performance of the Sentio bone conduction implant (a device that helps you hear by sending sound through the skull) in teenagers aged 12 to 17. It may be an option if you have certain types of hearing loss that cannot be helped by regular hearing aids.
Atlanta, GeorgiaAges 12–18 - NCT06844214RecruitingPhase 1/Phase 2
Gene therapy trial for myotonic dystrophy type 1
This trial tests a one-time gene therapy (SAR446268) for people with non-congenital myotonic dystrophy type 1. It aims to see if the treatment is safe and can improve muscle symptoms like stiffness and weakness.
Gainesville, FloridaAges 10–55 - NCT06844279Recruiting
Anesthesia depth monitoring for recovery after spinal surgery in older adults
This study tests whether carefully monitoring how deep your anesthesia is during spinal surgery can help older adults recover better and think more clearly afterward.
AnkaraAges 65 years+ - NCT06844370Recruiting
Home vs hospital NIV care for MND
This study compares two ways of starting non-invasive ventilation (NIV) — a breathing machine — for people with motor neurone disease (MND). It aims to see if starting NIV at home is as safe and effective as starting it in the hospital.
CambridgeAges 18 years+ - NCT06844461Recruiting
Quality of life after acoustic neuroma treatment
This study looks at how acoustic neuroma and its treatments affect your quality of life, and whether you later regret the choices you made. Researchers want to know if follow-up or surgery makes a difference.
BolognaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.