Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,465 recruiting studies in this area right now.
By phase
- Not applicable9,803
- Phase 2786
- Phase 1573
- Phase 3536
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3120
Top conditions
- Stroke855
- Parkinson Disease424
- Multiple Sclerosis341
- Alzheimer Disease340
- Dementia227
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea154
- Spinal Cord Injuries153
- Traumatic Brain Injury153
- Insomnia152
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California674
- Massachusetts302
- New York292
- Florida278
- Texas267
- Maryland244
- Arizona214
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,463 total
- NCT06842745RecruitingPhase 2
Brain stimulation plus language therapy for mild aphasia
This study tests whether combining brain stimulation (TMS) with language therapy can help people with mild aphasia after a stroke. It aims to improve speaking and understanding.
Philadelphia, PennsylvaniaAges 40–85 - NCT06842797Recruiting
Do weighted blankets improve sleep quality?
This study tests whether a weighted blanket can help healthy people sleep better. If you're a healthy adult, you may be able to join and use a weighted blanket at home.
Trikala, ThessalyAges 18–45 - NCT06843252Recruiting
Home-based brain stimulation for Huntington's disease symptoms
This study tests whether a gentle brain stimulation device (tDCS) used at home can help improve thinking and behavior in people with Huntington's disease. A caregiver is needed to be present during treatment and help with questionnaires.
San Antonio, TexasAges 18–85 - NCT06843590RecruitingPhase 2
Study of ALKS 2680 for Idiopathic Hypersomnia
This trial tests a new medicine called ALKS 2680 for people with Idiopathic Hypersomnia (a condition that causes extreme sleepiness without a clear cause). The goal is to see if it is safe and effective at helping you stay awake during the day.
Cullman, AlabamaAges 18–70 - NCT06843616Recruiting
Study of a disposable brain clot removal scope for bleeding stroke
This study tests a new disposable tube with a camera (endoscope) that doctors use to remove a blood clot from the brain after a bleeding stroke. It is designed for people who are stable enough for surgery and whose bleed is in a part of the brain that is reachable with this tool.
Guiyang, GuizhouAges 18–80 - NCT06844071Recruiting
Safety of Sentio bone conduction implant in teens
This study tests the safety and performance of the Sentio bone conduction implant (a device that helps you hear by sending sound through the skull) in teenagers aged 12 to 17. It may be an option if you have certain types of hearing loss that cannot be helped by regular hearing aids.
Atlanta, GeorgiaAges 12–18 - NCT06844214RecruitingPhase 1/Phase 2
Gene therapy trial for myotonic dystrophy type 1
This trial tests a one-time gene therapy (SAR446268) for people with non-congenital myotonic dystrophy type 1. It aims to see if the treatment is safe and can improve muscle symptoms like stiffness and weakness.
Gainesville, FloridaAges 10–55 - NCT06844279Recruiting
Anesthesia depth monitoring for recovery after spinal surgery in older adults
This study tests whether carefully monitoring how deep your anesthesia is during spinal surgery can help older adults recover better and think more clearly afterward.
AnkaraAges 65 years+ - NCT06844370Recruiting
Home vs hospital NIV care for MND
This study compares two ways of starting non-invasive ventilation (NIV) — a breathing machine — for people with motor neurone disease (MND). It aims to see if starting NIV at home is as safe and effective as starting it in the hospital.
CambridgeAges 18 years+ - NCT06844461Recruiting
Quality of life after acoustic neuroma treatment
This study looks at how acoustic neuroma and its treatments affect your quality of life, and whether you later regret the choices you made. Researchers want to know if follow-up or surgery makes a difference.
BolognaAges 18 years+ - NCT06844734Recruiting
Study of ITB treatment for hereditary spastic paraplegia
This trial tests if a treatment called ITB (intrathecal baclofen) can help reduce muscle stiffness in people with hereditary spastic paraplegia (HSP). Participants will receive the treatment and be followed over time to see how well it works.
Shanghai, Shanghai MunicipalityAges 14–70 - NCT06844877Recruiting
Italian NCL Registry for Batten disease
This trial is creating a registry (a secure database) for people with a confirmed genetic diagnosis of NCL (Batten disease). The goal is to collect information over time to help researchers understand the disease better and plan future treatments.
PisaAges Any age - NCT06844981Recruiting
Latin dancing for better sleep in Hispanic cancer survivors
This study tests if 8 weeks of Latin dancing can improve sleep quality for Hispanic and Latino(a) cancer survivors who have trouble sleeping. You would be randomly assigned to either start dancing right away or wait, and you'll help researchers see if moving to the music helps you rest better.
New Brunswick, New JerseyAges 18 years+ - NCT06845644Recruiting
MRI scans to track nerve damage in neuropathy patients
This study uses MRI scans to look at nerve and muscle changes over time in people with inherited or acquired nerve conditions. It may help doctors better understand how these diseases progress.
MarseilleAges 18 years+ - NCT06845657Recruiting
Hip strengthening exercises for knee arthritis
This study tests if strengthening the hip muscles can reduce knee pain and improve function in people with knee osteoarthritis. It may help you if you have had knee pain for at least 3 months and are between 40 and 60 years old.
Islamabad, Punjab ProvinceAges 40–60 - NCT06845709Recruiting
Balance and eye exercises for stroke recovery in older adults
This study tests two simple exercise programs—one for balance and strength (Otago exercises) and one for eye-head coordination (gaze stabilization)—to help older adults who have had a stroke improve their walking, balance, and quality of life.
Islamabad, FedralAges 50–70 - NCT06845722Recruiting
Balance and cognitive training for multiple sclerosis
This trial tests whether combining balance exercises with brain-training activities can help improve walking and thinking in people with multiple sclerosis. It is for people aged 40–55 who have mild cognitive problems and balance issues.
LahoreAges 40–55 - NCT06845904Recruiting
Spinal cord stimulation for bladder control after injury
This trial tests whether using mild electrical pulses on the spinal cord can help people with spinal cord injuries regain better control of their bladder. It might be an option if you've tried other treatments without success.
Lausanne, Canton of VaudAges 18 years+ - NCT06846190Recruiting
Modified arm therapy versus virtual reality for children with cerebral palsy
This study compares two types of therapy to help children with cerebral palsy use their weaker arm better. One therapy involves gently restraining the strong arm to encourage use of the weaker arm, and the other uses virtual reality games to practice arm movements.
Lahore, Punjab ProvinceAges 6–12 - NCT06846970Recruiting
Hot spring therapy plus physical therapy for chronic back pain
This study tests whether adding hot spring therapy (balneotherapy) to a standard physical therapy program can improve pain and function for people with chronic nerve-related back pain. It may help if you have long-term sciatica-like pain and have not had recent hot spring treatments.
Afyonkarahisar, CentralAges 18–75 - NCT06847074Recruiting
Sleep better after stroke with a morning exercise program
This study tests whether a morning exercise program can help improve sleep quality in people who had a stroke at least a year ago. If you're 55 or older and have trouble sleeping, this trial may be a good fit.
Vancouver, British ColumbiaAges 55 years+ - NCT06847282Recruiting
Motor skills study for children with FSHD
This study looks at how children with FSHD move and function over time. It uses walking tests and optional MRI scans to understand muscle changes. Your child's participation could help researchers learn more about FSHD progression in kids.
Palo Alto, CaliforniaAges 5–17 - NCT06847295Recruiting
Spinal cord stimulation for standing and walking after paralysis
This trial tests if a device that sends mild electrical pulses to the spinal cord, combined with daily therapy, can help people with chronic spinal cord injury regain some ability to stand or walk. It also looks at reducing muscle spasms and improving quality of life.
São Paulo, São PauloAges 18–50 - NCT06848140Recruiting
Brain stimulation for word-finding problems after TBI
This study tests whether non-invasive brain stimulation can help people with chronic traumatic brain injury (TBI) find words more easily. It involves sessions at Beth Israel Deaconess Medical Center in Boston.
Boston, MassachusettsAges 18–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,465 recruiting neurology studies from the U.S. registry right now, out of 19,709 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.