Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06833645Recruiting
PET scans to spot early Alzheimer's changes
This trial uses special PET scans to see amyloid and tau proteins in the brain, which are linked to Alzheimer's. It aims to find these changes early, in people with mild memory problems or early-stage Alzheimer's.
Chengdu, SichuanAges 18 years+ - NCT06833710Recruiting
Ear acupressure for better sleep in nurses
This study tests if applying small acupressure stickers on specific ear points can improve sleep quality for nurses. It may help if you have poor sleep and want a simple, drug-free option.
TaipeiAges 18–65 - NCT06834061Recruiting
Using ultrasound to diagnose and manage carpal tunnel syndrome
This trial tests if ultrasound can help doctors better diagnose and track carpal tunnel syndrome (a condition where a nerve in your wrist gets squeezed). It may lead to better treatment and follow-up without extra tests.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06834191Recruiting
Parkinson's and immunosuppressant drugs study
This study looks at how taking immunosuppressive medicines affects the course of Parkinson's disease. It compares people with Parkinson's who have been on these drugs for over a year to those who have never taken them regularly.
WarsawAges Any age - NCT06834269Recruiting
Magnetic stimulation for ALS: a study on slowing progression
This study tests a gentle, non-invasive magnetic stimulation applied to the head to see if it can slow the progression of ALS. It uses a special device that creates a static magnetic field, and researchers will also look for biomarkers in your body that may help predict how the disease will progress.
Roma, RMAges 18 years+ - NCT06834724Recruiting
CPAP for sleep apnea and chronic pain
This study looks at whether CPAP treatment improves pain and daily life in people who have both sleep apnea and chronic pain. It tests if starting CPAP for the first time can help these symptoms.
BrusselsAges 18 years+ - NCT06835283Recruiting
Brain stimulation for mood and behavior in Alzheimer's
This study tests a non-invasive brain stimulation treatment designed to help with difficult mood and behavior symptoms in people with Alzheimer's disease. If you are a veteran with mild to moderate Alzheimer's and have troubling symptoms like agitation, the treatment may help improve your quality of life.
Houston, TexasAges 65–85 - NCT06835426Recruiting
Imaging removed tissue during cancer surgery
This study tests a high-resolution PET-CT scanner that takes pictures of tissue removed during surgery to help doctors see if all the cancer has been removed. You might qualify if you are having surgery for a range of cancers including breast, prostate, thyroid, skin, gastrointestinal, or brain tumors.
Ghent, Oost VlaanderenAges 18 years+ - NCT06835595Recruiting
Brain signals as markers of thinking changes in Parkinson's
This study uses a safe, noninvasive brain stimulation method (transcranial magnetic stimulation, or TMS) to look at brain signals related to thinking and memory in people with Parkinson's disease. The goal is to find a better way to measure cognitive changes over time.
Trieste, Friuli Venezia GiuliaAges 18 years+ - NCT06836687Recruiting
How a new epilepsy definition affects diagnosis after a first seizure
This study looks at how the new 2014 definition of epilepsy from the ILAE affects diagnosis after a first seizure. It is for adults who have had their very first seizure and can give consent.
Marburg, HesseAges 18 years+ - NCT06836739Recruiting
Genital nerve stimulation for bowel function after spinal cord injury
This trial tests whether gentle electrical stimulation of the genital nerve can help people with spinal cord injury improve bowel control. If it works, this at-home device could reduce constipation and make bowel care easier and more predictable.
Cleveland, OhioAges 18 years+ - NCT06836856RecruitingPhase 1/Phase 2
Beta blockers after traumatic brain injury: a study
This trial tests whether giving a beta blocker drug after a moderate or severe traumatic brain injury can improve recovery. It is for patients who have a brain injury but only minor or no other injuries.
ZagazigAges 18–75 - NCT06837025Recruiting
Fascial manipulation for kids with cerebral palsy
This trial tests a hands-on technique called fascial manipulation to see if it improves movement and walking in children with cerebral palsy. It is for families living near Helsinki.
HelsinkiAges 7–14 - NCT06837272Recruiting
Gut health and brain health in Alzheimer's disease
This study looks at how the bacteria in your gut might be connected to memory and thinking problems in Alzheimer's disease. It may help us understand if changes in the gut can affect brain health.
Jining, ShandongAges 60–80 - NCT06837324Recruiting
Smart glove therapy for arm weakness after brain injury
This study tests a smart glove system that provides arm and hand exercises at home for people who had a brain injury (like a stroke) more than 3 months ago and have weakness on one side. The goal is to improve use of the affected arm without needing frequent hospital visits.
SeoulAges 19–85 - NCT06837311Recruiting
Smoking cessation after stroke via smartphone monitoring
This study tests a smartphone-based program that helps people who recently had a stroke quit smoking. It uses digital monitoring and support as part of your regular post-stroke follow-up to lower the risk of another stroke.
BordeauxAges 18–80 - NCT06837363Recruiting
Smart board rehab for arm weakness after brain injury
This trial tests a smart board therapy that you can do without in-person contact to help improve arm movement if you have weakness on one side from a stroke, brain injury, or tumor. It is for people who are at least 3 months past their diagnosis and can understand simple instructions.
SeoulAges 19–85 - NCT06837844Recruiting
Pain relief study for knee replacement surgery
This trial tests a combination of two pain-relief methods after total knee replacement: a spinal injection and a nerve block in the thigh. It aims to provide better pain control during and after surgery.
Kafr ash Shaykh, KafrelsheikhAges 18–75 - NCT06838013Recruiting
Electrical stimulation to improve leg movement after stroke
This trial tests a new way to help people with stroke move their legs better by combining electrical stimulation on the back and leg. If you have had a stroke more than 6 months ago and can already walk with or without a cane, this treatment might help strengthen ankle muscles and make walking easier.
Hong KongAges 50–85 - NCT06838143Recruiting
Ilaris real-world study for periodic fevers and sJIA
This study watches how people with certain periodic fever syndromes or a severe type of childhood arthritis (sJIA) do on the medicine Ilaris during their regular doctor visits. It collects information to see how well the medicine works in everyday care.
SeoulAges 2–100 - NCT06838403Recruiting
Reflex therapy for children with cerebral palsy and swallowing issues
This study tests if a special reflex therapy helps children with cerebral palsy improve mouth movements and reduce drooling, using a type of exercise called Masgutova Neurosensorimotor Reflex Integration.
GizaAges 1–4 - NCT06838572Recruiting
Cooling the wrist to reduce pain from arterial line placement
This study tests whether cooling the skin on your wrist before a routine arterial line placement (a small tube in your wrist artery) can reduce the pain of the procedure. If you are having surgery and need an arterial line, this might help make the experience more comfortable.
Chongqing, Chongqing MunicipalityAges Any age - NCT06838637Recruiting
Spinal cord stimulation at home for blood pressure issues
This trial tests using a gentle electrical device on your spine at home to help with dizziness from low blood pressure (orthostatic hypotension). It is for people with chronic spinal cord injury or multiple system atrophy who live in British Columbia.
Vancouver, British ColumbiaAges 19–70 - NCT06838676RecruitingPhase 2
ACT001 for DIPG and H3K27-altered high-grade gliomas
This trial tests a drug called ACT001 for people with diffuse intrinsic pontine glioma (DIPG) or certain high-grade gliomas that have a specific genetic change (H3K27-altered). It includes two groups: one for newly diagnosed DIPG after radiation, and another for progressive or recurrent disease.
Aurora, ColoradoAges 1–39
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.