Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,465 recruiting studies in this area right now.
By phase
- Not applicable9,805
- Phase 2785
- Phase 1574
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3120
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea154
- Spinal Cord Injuries153
- Traumatic Brain Injury153
- Insomnia152
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California673
- Massachusetts304
- New York293
- Florida278
- Texas268
- Maryland244
- Alabama213
- Arizona213
- Illinois193
- Pennsylvania177
Recruiting studies12,463 total
- NCT06883708Recruiting
Online program for dementia caregivers in Malaysia
This trial tests an online program called iSupport-Malaysia to help people who care for a family member with dementia. It aims to reduce stress, burden, and symptoms of depression or anxiety.
Petaling Jaya, Kuala LumpurAges 18–100 - NCT06883981Recruiting
Studying memory formation with everyday recordings
This study uses recordings of your everyday life to understand how people form personal memories. It may help if you have healthy memory or just mild memory changes.
Salt Lake City, UtahAges 18 years+ - NCT06884358Recruiting
Heart and exercise capacity in Fabry disease
This study looks at how Anderson-Fabry disease affects your heart and ability to exercise. Researchers want to understand this better by testing your heart function and how well you can do physical activity.
Brescia, BresciaAges Any age - NCT06884722Recruiting
Brain study of social perception in Parkinson's disease
This study uses brain scans to understand how people with Parkinson's disease process social cues, like faces and emotions. It may help researchers learn more about how Parkinson's affects social thinking.
BronAges 30–75 - NCT06885502Recruiting
Stroke rehab with motor and cognitive assistance
This trial tests a personalized system that helps stroke survivors improve arm movement and thinking skills. It uses a device that guides your arm and mind through exercises, and you may benefit if you had a stroke at least 3 months ago and have some arm function.
Cluj-NapocaAges 18 years+ - NCT06887283Recruiting
Essen Amyloidosis Registry Study
This study collects information from people with suspected or confirmed amyloidosis. The goal is to learn more about the condition and improve patient care.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT06885541Recruiting
Measuring internal tremors in Parkinson's patients
This study uses a device on your body to detect internal tremors (tiny vibrations you may feel inside) in Parkinson's disease. It helps researchers understand these tremors better and compare them to people without Parkinson's.
Toulouse, OccitanieAges 18–80 - NCT06885918Recruiting
ALS Research Collaborative study
This study is a research collaborative that collects information from people with ALS or their families. It aims to better understand the disease and find markers that could help develop treatments.
Watertown, MassachusettsAges 18 years+ - NCT06885957Recruiting
Monoclonal antibodies for AQP4-positive NMOSD
This trial is testing monoclonal antibody treatments for people with a specific type of neuromyelitis optica spectrum disorder (NMOSD) caused by AQP4 antibodies. It aims to see if these targeted therapies can help control the disease and prevent relapses.
Wuhan, HubeiAges 18–65 - NCT06886737RecruitingPhase 1
Home vision therapy for veterans with double vision
This trial tests if a 12-week home-based vision therapy program can improve double vision and reading issues in veterans with traumatic brain injury. It targets a specific problem called convergence insufficiency, where the eyes don't work together when looking at close objects.
Cleveland, OhioAges 18–80 - NCT06887062RecruitingPhase 2
Testing dapagliflozin and bosentan for large vessel vasculitis
This trial tests two drugs, dapagliflozin and bosentan, to see if they help people with large vessel vasculitis who have been in remission for at least 6 months. The goal is to prevent flares and improve blood vessel health.
EdinburghAges 18 years+ - NCT06887088RecruitingPhase 2
Study of encorafenib, binimetinib, cemiplimab, and fianlimab for melanoma with brain metastases
This trial tests a combination of targeted drugs (encorafenib and binimetinib) followed by immunotherapy (cemiplimab and fianlimab) for people with advanced melanoma that has spread to the brain and is causing symptoms. The goal is to see if this approach can shrink tumors and help control the disease.
A Coruña, A CoruñaAges 18 years+ - NCT06887114Recruiting
Lumbar back therapy for better walking and balance after stroke
This study tests a gentle, hands-on therapy called Mulligan Mobilization for the lower back. It may help improve walking, balance, and body awareness after a stroke.
AnkaraAges 30–65 - NCT06887231Recruiting
Virtual reality and brain stimulation for early stroke recovery
This study tests whether using virtual reality (a special headset with games) combined with mild electrical stimulation on the scalp can help people recover arm movement early after a stroke. It is for people who already have some movement in their affected arm and are in the subacute phase (1 week to 3 months after stroke).
Vienna, State of ViennaAges 18–80 - NCT06887777RecruitingPhase 2
Testing RAVICTI for PDH deficiency in young people
This study tests if a medicine called Glycerol Phenylbutyrate (RAVICTI) is safe and helpful for children and young adults with a specific type of PDH deficiency, a rare genetic condition affecting energy use. If you qualify, you may get a new treatment option.
Paris, FranceAges 2–25 - NCT06887894Recruiting
Studying unstable plaque in the carotid artery
This trial looks at specific markers in the blood to better understand unstable plaque in the carotid artery. It may help doctors identify which patients are at higher risk for stroke.
Roma, RMAges 18 years+ - NCT06888791Recruiting
Hydro dissection for frozen shoulder: ultrasound vs X-ray guidance
This trial compares two ways to guide a fluid injection for frozen shoulder—one using ultrasound and one using X-ray. The goal is to see which technique works better to reduce pain and improve movement.
AnkaraAges 18–80 - NCT06888960RecruitingEarly Phase 1
Testing CC312 for people with autoimmune diseases
This early-phase study tests a new drug called CC312 in patients with certain autoimmune diseases like lupus, myositis, scleroderma, rheumatoid arthritis, immune thrombocytopenia, or autoimmune hemolytic anemia. The goal is to see if it's safe and how the body handles it.
Tianjin, ChinaAges 18 years+ - NCT06889415Recruiting
Rheumatoid Arthritis and Bone & Muscle Loss: A Study
This study looks at how rheumatoid arthritis relates to bone thinning and muscle loss in people over 50. It aims to find what factors are linked to these conditions.
Konya, SelçukluAges 50 years+ - NCT06889480Recruiting
Deep brain stimulation for severe Tourette syndrome
This trial tests a surgical procedure using deep brain stimulation to treat severe Tourette syndrome that hasn't improved with other treatments. It may help reduce tics by targeting specific areas in the brain.
Beijing, Beijing MunicipalityAges 18–60 - NCT06889818Recruiting
Alzheimer's treatment and diagnostics registry study
This study creates a registry for people who are using newly approved Alzheimer's medications. It tracks how these treatments work over time and may help researchers learn more about diagnosing and treating Alzheimer's.
IncheonAges 19 years+ - NCT06890702Recruiting
Testing new blood markers for brain blood flow problems
This study is testing whether certain substances in your blood can help doctors better detect and understand problems with blood flow in the brain. Researchers hope these new 'biomarkers' could lead to faster and more accurate diagnosis of conditions like stroke and mini-stroke.
Wuhan, HubeiAges 18–90 - NCT06890897Recruiting
Esketamine with pulsed radiofrequency for shingles-related face pain
This trial tests whether adding esketamine (a medicine related to ketamine) to a standard nerve treatment (pulsed radiofrequency) can better relieve face pain caused by shingles. It may help if you have ongoing, moderate-to-severe pain in your face or scalp.
BeijingAges 18 years+ - NCT06890923RecruitingPhase 2
Nasal foralumab for non-active secondary progressive MS
This trial tests a nasal spray medication, foralumab, to see if it can help people with non-active secondary progressive multiple sclerosis. It is only for people who completed a previous related study (TILS-021).
Boston, MassachusettsAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,465 recruiting neurology studies from the U.S. registry right now, out of 19,759 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.