Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,473 recruiting studies in this area right now.
By phase
- Not applicable9,815
- Phase 2785
- Phase 1573
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia152
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California674
- Massachusetts306
- New York293
- Florida277
- Texas270
- Maryland245
- Arizona213
- Alabama212
- Illinois193
- Pennsylvania177
Recruiting studies12,471 total
- NCT07138963Recruiting
Gene study in children with congenital muscle weakness
This study looks at how genes affect symptoms in children with congenital myopathies or congenital muscular dystrophies. It may help doctors better understand these conditions.
CairoAges 1–18 - NCT07139015Recruiting
Comparing two hand therapies after stroke
This trial compares mirror therapy and CIMT to improve hand and arm function in people who have had a stroke within the past 6 months. It could help you regain movement in your affected hand.
Lahore, Punjab ProvinceAges 40 years+ - NCT07139301Recruiting
Timing of blood thinners after stroke clot removal in atrial fibrillation
This study aims to find the best time to start blood thinners after emergency clot removal in people with atrial fibrillation who had a stroke. It may help reduce the risk of another stroke or bleeding.
Ma’anshan, AnhuiAges 18 years+ - NCT07139379Recruiting
Virtual reality therapy for stroke recovery
This trial tests whether virtual reality exercises can help improve arm and hand function after a stroke. It uses a special mirror therapy technique combined with cooperative tasks in a virtual environment.
Tainan, TaiwanAges 18–80 - NCT07139483Recruiting
Preventing chronic phantom limb pain with mirror therapy and brain stimulation
This study tests whether combining mirror therapy (looking at a reflection of your healthy limb) with a gentle brain stimulation technique called tDCS can prevent phantom limb pain from becoming long-lasting. It is for people who recently had a limb amputated and are already starting to feel phantom pain.
Raanana, IsraelAges 18 years+ - NCT07139496Recruiting
Spinal cord stimulation for injury recovery
This trial tests if placing electrodes near the injury site and in the lower back can help people with spinal cord injury recover movement or function. You must have had the injury for more than 2 years.
Hong KongAges 18–70 - NCT07139743RecruitingPhase 1
Obe-cel for progressive multiple sclerosis that is getting worse
This study tests a new treatment called obe-cel, a type of CAR T-cell therapy, for people with progressive multiple sclerosis that hasn't responded to other treatments. It aims to see if this therapy can slow or stop the disease from getting worse.
Redwood City, CaliforniaAges 18–60 - NCT07140601Recruiting
Environmental pollutants and brain health study
This study looks at how environmental pollutants might affect brain health and neurological disorders. If you join, you will help researchers understand possible links between pollution and conditions like Parkinson's or Alzheimer's.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07140731Recruiting
Symani Restore study for moyamoya disease surgery
This study tests if the Symani surgical system helps surgeons perform a delicate brain blood-vessel bypass in people with moyamoya disease. It may offer a precise, minimally invasive option for those needing neurosurgery.
Buffalo, New YorkAges 18 years+ - NCT07140913RecruitingPhase 3
Testing KarXT for bipolar I mania with mood stabilizers
This study tests whether adding KarXT to lithium, valproate, or lamotrigine helps calm manic episodes in people with bipolar I disorder. It aims to see if the combination is safe and works better than the mood stabilizer alone.
Bentonville, ArkansasAges 18–65 - NCT07140952Recruiting
Heart-healthy diet and exercise for stroke survivors
This study tests a heart-healthy diet and exercise plan for stroke survivors to improve health and fitness. It is done virtually to make it easy to join from home.
Florence, South CarolinaAges 45–80 - NCT07141108Recruiting
Using a digital tool to track chronic pain and improve quality of life
This trial tests a digital tool that helps you track your pain and activity level. The goal is to see if using the tool can improve your quality of life. You would use a smartphone or tablet app and share updates with your primary care team.
Malmö, Skåne CountyAges 18 years+ - NCT07141303RecruitingPhase 3
Steroid after stroke clot removal for anterior circulation large vessel occlusion
This trial tests if giving a steroid (methylprednisolone) directly into the brain artery after successful clot removal improves recovery. It is for people who had a large stroke in the front part of the brain and got the clot out within 24 hours.
Xi'an, ShaanxiAges 18–80 - NCT07141329RecruitingPhase 2
Long-term study of SPN-817 for focal seizures
This study gives SPN-817 to people who completed a prior study of the same drug, to see if it stays safe and works well over a longer time. You may qualify if you already finished that study and have stable seizure medicine.
Port Charlotte, FloridaAges 18 years+ - NCT07142954RecruitingPhase 3
Alzheimer's research study for healthy people
This study is looking at healthy people with no memory concerns to better understand early signs of Alzheimer's disease. You would provide samples and do thinking tests, but you won't take any experimental medicines.
Houston, TexasAges 55–75 - NCT07143149Recruiting
Smart tool for cholesterol after stroke or mini-stroke
This trial tests a smart computer tool that helps doctors manage your cholesterol treatment with Evolocumab (Repatha). If you have had a recent stroke or mini-stroke and are already taking this medicine, the tool may help you reach your LDL (bad cholesterol) goal faster.
BeijingAges 18 years+ - NCT07143266Recruiting
Sleep study for people with pituitary and hypothalamus conditions
This study looks at sleep problems in people whose hypothalamus or pituitary gland does not work normally. It compares their sleep with healthy volunteers to better understand how these conditions affect rest.
BarcelonaAges 18–70 - NCT07143734RecruitingPhase 2
Brain stimulation for early Alzheimer's disease
This study tests a new, noninvasive brain stimulation method called Transcranial Pulse Stimulation (TPS) for people in the early stages of Alzheimer's disease. The goal is to see if it can help improve symptoms.
Hong KongAges 60–90 - NCT07143799Recruiting
Scalp block vs general anesthesia for subdural hematoma drainage
This study compares two ways to manage pain during surgery to drain a subdural hematoma (a collection of blood pressing on the brain). Some patients will get a scalp block (numbing injections in the head) while others will receive general anesthesia (being put to sleep). The goal is to see which approach works better and has fewer side effects.
SohagAges 18–75 - NCT07144007Recruiting
Preventing agitation after rhinoplasty with propofol and dexmedetomidine
This study tests whether giving two medicines, propofol and dexmedetomidine, during rhinoplasty can help prevent confusion or restlessness when waking up from anesthesia. It may be a good option if you are having nose surgery and are generally healthy.
Van, TuşbaAges 18–65 - NCT07144423Recruiting
Comparing two drainage methods for chronic subdural hematoma
This trial compares two surgical techniques—using a small endoscope (camera) versus a single burr hole—to drain blood from a chronic subdural hematoma (a slow bleed on the brain surface). The goal is to see which method leads to better recovery and fewer complications.
Beijing, Beijing MunicipalityAges 18–90 - NCT07144436Recruiting
Pain after stroke: brain scan and treatment study
This trial tests whether a special kind of brain scan (called tAN-fMRI) can help understand and treat pain that happens after a stroke. You may qualify if you had a stroke at least 6 months ago and are between 18 and 80 years old.
Charleston, South CarolinaAges 18–80 - NCT07144631Recruiting
Nerve stimulation for restless legs in pregnancy
This trial tests if a small nerve stimulation device can safely and effectively reduce restless legs symptoms in pregnant people. If you are between 21 and 26 weeks pregnant with a confirmed diagnosis of restless legs syndrome (RLS), you may be eligible.
Providence, Rhode IslandAges 18 years+ - NCT07144930Recruiting
Cognitive-motor training for stroke and Moyamoya disease
This trial tests a combined thinking and movement training program for people who have had a stroke or have Moyamoya disease and still have some thinking or movement problems. It may help improve both mental and physical abilities.
TaipeiAges 20–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,473 recruiting neurology studies from the U.S. registry right now, out of 19,792 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.