Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT05901818RecruitingPhase 1
Testing a patient’s own stem-cell treatment for Parkinson’s
This Phase 1 study tests whether an “autologous” (from your own body) iNSC-DAP stem-cell treatment is safe and may help symptoms in Parkinson’s disease. It is designed mainly to check safety, while also watching for signs of improvement.
Beijing, Beijing MunicipalityAges 30–85 - NCT06841198Recruiting
Heart and blood vessel health after spinal cord injury
This study looks at how the heart and blood vessels change in the first year after a spinal cord injury. It also tests if electrical stimulation can help improve low blood pressure, which is common after injury.
West Orange, New JerseyAges 18–75 - NCT07328451RecruitingPhase 1
Study of DNL628 for people with early Alzheimer's disease
This trial tests an experimental drug, DNL628, to see if it is safe and how it affects people with early Alzheimer's disease. It may help slow the disease by targeting a specific process in the brain.
's-HertogenboschAges 18–75 - NCT07677631Recruiting
Emotional allodynia in fibromyalgia: a questionnaire study
This study compares how people with fibromyalgia and those with other long-term pain conditions experience emotional pain (like feeling hurt by emotions). You will fill out a questionnaire about emotional sensitivity. The goal is to see if emotional allodynia (pain from emotions) is more common in fibromyalgia.
BariAges 18 years+ - NCT07629115Recruiting
Long-term follow-up study for severe Parkinson's gene therapy
This study follows patients who previously received IPS101A, an experimental gene therapy treatment for severe Parkinson's disease. Researchers want to check how you're doing over time and gather information about the treatment's long-term effects.
SeoulAges 50–80 - NCT07678515Enrolling by invitation
Massage and scents to help people with dementia eat better
This study tests whether a gentle massage of the salivary glands (under the jaw) and pleasant smells (like essential oils) can help people with dementia who have trouble eating. It may encourage them to eat by mouth and reduce feeding difficulties.
TainanAges Any age - NCT07267910Enrolling by invitation
Measuring inner ear function with weak electrical stimulation
This study uses a weak electrical current to test how well your inner ear balance system works. It may help people with certain inner ear conditions like vestibular schwannoma or vestibular neuritis.
HelsinkiAges 18–70 - NCT02922894RecruitingPhase 4
Testing sleep apnea care in people with spinal cord injury
This study looks at treatment for sleep apnea (breathing pauses during sleep) in adults with a spinal cord injury. If you qualify, the trial team may help manage sleep-related breathing problems and track how well the treatment works.
Detroit, MichiganAges 18–89 - NCT00695214RecruitingPhase 2
Test with medicine-assisted sleep endoscopy for sleep apnea
This trial studies how well a procedure done while you sleep helps doctors understand the blockage causing obstructive sleep apnea and plan surgery. You may be helped if you’re an adult with sleep apnea who is considering surgical treatment.
Santa Monica, CaliforniaAges 18 years+ - NCT07674004Recruiting
Testing a new flow diverter for brain aneurysms
This trial tests a special metal mesh tube, called a flow diverter, to treat unruptured brain aneurysms. The goal is to see how safe and effective it is for preventing strokes.
Zhengzhou, HenanAges 18–75 - NCT07497399RecruitingPhase 2
Testing a diabetes drug for weight loss in MS
This trial tests if a GLP-1 receptor agonist can help people with multiple sclerosis who have a high BMI. It may reduce inflammation and improve health.
Baltimore, MarylandAges 18–60 - NCT07526987RecruitingPhase 3
Minocycline to Help Recovery After Acute Stroke Treatment
This study tests whether an antibiotic called minocycline, given alongside standard stroke treatment (clot-busting medication), can help reduce brain damage and improve recovery. You would receive minocycline around the time of your clot-busting treatment.
Liaocheng, ShandongAges 18–80 - NCT07341763Recruiting
Brain stimulation for better mobility in vision loss
This study tests whether a safe, noninvasive brain stimulation technique (called tDCS) can help people with vision loss from retinitis pigmentosa, rod-cone dystrophy, or advanced glaucoma move around more easily and safely. Participants will do walking and orientation tasks while receiving the stimulation.
Waterloo, OntarioAges 18 years+ - NCT07345715Recruiting
Melatonin vs. dexmedetomidine for preventing agitation after tonsil surgery in children
This study tests whether giving children either oral melatonin or a nebulized sedative (dexmedetomidine) before surgery can reduce confusion and restlessness (emergence agitation) when they wake up from anesthesia. It may help children recover more calmly after adenotonsillectomy.
Tanta, El-GharbiaAges 3–7 - NCT07345949Recruiting
Study of skin inflammation in dermatomyositis
This trial looks at a type of skin inflammation called panniculitis that can happen in people with dermatomyositis. The goal is to learn more about this condition so that better treatments can be developed.
StrasbourgAges 1 year+ - NCT07346755Recruiting
Nerve block and shoulder awareness in stroke-related pain
This study tests whether a nerve block (freezing a nerve near the shoulder) combined with joint position testing can reduce shoulder pain and improve movement in people who have had a stroke.
Istanbul, IstanbulAges 18–80 - NCT07347028Recruiting
Trigger point injections for knee osteoarthritis pain
This trial tests whether injecting medication into muscle knots (trigger points) can reduce knee pain in people with knee osteoarthritis. It may be an option if other treatments haven't helped enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07347431Recruiting
AI tool to understand memory clinic experiences
This study uses a computer program to understand how people with memory problems and their carers talk about their experiences. It aims to help doctors better support dementia care.
North ShieldsAges 65 years+ - NCT07347587Recruiting
Finding the right blocked artery in stroke using CT scans
This study looks at how well different CT scans can identify which artery is blocked in people having a stroke. It may help doctors choose the best treatment faster.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07347691Recruiting
AI predicts atrial fibrillation after stroke of unknown cause
This trial uses an artificial intelligence (AI) program to see if it can predict which patients who had a stroke from an unknown cause might develop atrial fibrillation (an irregular heart rhythm). If you have a small heart monitor already implanted, the AI will analyze your ECGs to find early signs of AFib, which could help prevent future strokes.
AnsanAges 30 years+ - NCT07347730Recruiting
Trigger point injections for chronic headache from the neck
This study tests whether injections into muscle trigger points can reduce chronic headache pain that starts in the neck. It may help people who have not found relief from standard pain medications.
Beijing, Beijing MunicipalityAges 18–65 - NCT07348471Recruiting
Gut bacteria transplant for ICU delirium
This study tests whether giving a transplant of healthy gut bacteria (called fecal microbiota transplantation) can help treat delirium in ICU patients. It may improve brain function by restoring gut health.
WuhanAges 18–80 - NCT07348601RecruitingPhase 2
Study of CSTI-500 for people with Prader-Willi syndrome
This trial tests an investigational drug called CSTI-500 for people with Prader-Willi syndrome who are in the hyperphagia (constant hunger) phase. It aims to see if the drug can improve behavior and reduce overeating. You and your caregiver will need to visit the clinic regularly and answer questions about symptoms.
Nashville, TennesseeAges 13–50 - NCT07348627RecruitingPhase 3
Opioid-free hip replacement study
This trial tests if using fewer opioids after hip replacement surgery can still control pain well. It uses a specific type of hip replacement called anterior total hip arthroplasty and aims to help patients recover with less reliance on strong pain medicines.
Atlanta, GeorgiaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.