Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT07438223Recruiting
Brain gym exercises for balance in children with spastic diplegia
This study tests whether simple 'brain gym' exercises can help children with spastic diplegia (a type of cerebral palsy) improve their balance and quality of life. It could be a good option if you have mild muscle stiffness and are between 6 and 8 years old.
Cairo, Faculty of Physical TherapyAges 6–8 - NCT07438652Recruiting
Mediterranean vs paleo diet for rheumatoid arthritis
This 12-week study compares two diets (Mediterranean and paleo) to see which one better helps rheumatoid arthritis symptoms, muscle health, and quality of life. It is for adults aged 40 to 60 who have been diagnosed with rheumatoid arthritis.
Cairo, Al-ManialAges 40–60 - NCT07438912Recruiting
Mind After Midnight: A study on late-night thinking and suicide risk
This study looks at how thinking changes late at night in people who have had suicidal thoughts in the past 6 months. The goal is to understand risk and find better ways to help.
Tucson, ArizonaAges 18–55 - NCT07438964Recruiting
Brain stimulation for MS fatigue
This study uses a safe, non-invasive brain stimulation technique to see if it can reduce fatigue in people with relapsing-remitting MS. It compares people with and without fatigue to understand how the brain is affected.
Berlin, State of BerlinAges 18–70 - NCT07439965Recruiting
Studying blood particles from different body areas in aneurysm patients
This trial looks at tiny particles in the blood called extracellular vesicles to see how they differ in patients with brain aneurysms. It may help doctors better understand these aneurysms and improve treatment.
Changchun, JilinAges 18–60 - NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT07440277Recruiting
Shunt vs. stent for IIH with vision loss risk
This study compares two treatments for Idiopathic Intracranial Hypertension (IIH) with severe papilledema (swollen optic nerves) and risk of vision loss: a CSF shunt (a tube to drain extra fluid) and a venous sinus stent (a mesh tube to open a narrowed vein). The goal is to see which works better and is more cost-effective.
BirminghamAges 18–63 - NCT07440667Recruiting
Fluid amounts during planned C-section and recovery
This trial compares giving less fluid versus more fluid during planned C-section surgery to see which approach leads to better recovery afterward.
Niğde, MerkezAges 18–45 - NCT07441057Recruiting
Studying a therapy for arm movement in kids with stroke
This study tests whether a therapy called CHRIST can help children who've had a stroke improve the movement and function of their affected arm and hand.
Mandi Bahāuddīn, Punjab ProvinceAges 7–12 - NCT07441382Recruiting
Comparing treatments for frail older adults with atrial fibrillation
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Guangzhou, GuangdongAges 75 years+ - NCT07441447Recruiting
Muscle strength and mass in inflammatory bowel disease
This study looks at muscle strength and muscle mass in people with inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis. It aims to understand how IBD affects muscles, which can help improve patient care.
Sakarya, AdapazarıAges 18 years+ - NCT07441915Recruiting
Sleep Sounds and Brain Training for Parkinson's with Mild Memory Problems
This trial tests whether playing soft sounds during sleep can boost the effects of a computer-based brain training program in people with Parkinson's disease who have mild memory or thinking issues. If you qualify, you'll use a headband that plays tones while you sleep and do brain exercises for several weeks.
Zurich, Canton of ZurichAges 18 years+ - NCT07441902Recruiting
Numbing medicine for lung surgery pain relief
This trial tests whether a numbing medicine (liposomal bupivacaine) injected near the ribs can reduce pain after lung surgery. If you qualify, you may experience less pain and need fewer painkillers after your operation.
Beijing, Beijing MunicipalityAges 18–64 - NCT07442188Recruiting
Comparing two numbing blocks for hernia surgery pain
This trial compares two types of numbing injections (nerve blocks) given before hernia surgery to see which one works better for pain after the operation. The blocks target muscles around the belly area to help you feel less pain and recover more comfortably.
Ankara, Yenimahalle\AnkaraAges 18–65 - NCT07442370Recruiting
Rotational exercises for fall risk in Parkinson's
This study tests if rotational exercises can lower fall risk and improve movement in people with early-stage Parkinson's. You would do simple, guided exercises over a set period.
Istanbul, SancaktepeAges 50–70 - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07442734Recruiting
Ear stimulation for stomach discomfort and sleep problems
This trial tests a treatment using gentle electrical stimulation on the ear to see if it helps people who have both functional dyspepsia (stomach discomfort) and trouble sleeping. It aims to improve both symptoms and understand how the treatment works.
Hangzhou, ZhejiangAges 18 years+ - NCT07443254RecruitingPhase 1/Phase 2
IR-led deep sedation study for image-guided procedures
This study tests if a radiologist can safely give deep sedation medicine (ketamine) for certain procedures instead of general anesthesia. It might help you avoid general anesthesia while still being comfortable.
Charleston, West VirginiaAges 18 years+ - NCT07443891Recruiting
Brain changes from vibration in laryngeal dystonia
This study uses a gentle vibrating device placed on the skin to see how it affects brain activity in people with laryngeal dystonia (a voice disorder). The goal is to learn more about how the brain controls voice and maybe find new ways to help.
Minneapolis, MinnesotaAges 18–75 - NCT07444047Recruiting
MRI study of brain lesions in older MS patients
This study uses MRI scans to compare brain lesions in older patients with multiple sclerosis versus those with small vessel disease. It aims to improve how doctors tell apart these conditions and may lead to better treatment choices.
Oslo, OsloAges 50–80 - NCT07444151Recruiting
Post-stroke fatigue perception study
This study explores fatigue after stroke. If you have ongoing tiredness that you believe stems from your stroke, researchers want to learn from your experience through a questionnaire.
Carouge, Canton of GenevaAges 18 years+ - NCT07444372Recruiting
CPAP for Sleep Apnea After Atrial Fibrillation Ablation
This trial tests whether starting CPAP therapy (a breathing mask used during sleep) after a heart procedure called atrial fibrillation ablation can help people with both sleep apnea and atrial fibrillation. It might lower the chance of the heart rhythm problem coming back.
Beijing, Beijing MunicipalityAges 18–75 - NCT07444476RecruitingPhase 3
Study of salanersen for spinal muscular atrophy (ages 15-60)
This trial tests a medicine called salanersen (BIIB115) to see how well it improves movement and how safe it is in people with spinal muscular atrophy (SMA). It includes those who have never taken an SMA drug or are currently on risdiplam and willing to switch.
Norfolk, VirginiaAges 15–60 - NCT07444580RecruitingPhase 1
RNA drug study for prion disease safety
This study tests an RNA-based drug designed to turn off the gene that causes prion disease. It aims to see if the drug is safe in people with early-stage symptoms.
Boston, MassachusettsAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.