Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT07493265RecruitingPhase 2
Study of E2086 for adults with narcolepsy
This study tests a new drug called E2086 to see if it can help reduce daytime sleepiness and sudden muscle weakness in adults with narcolepsy. It involves two groups: people with cataplexy (type 1) and those without (type 2).
Santa Ana, CaliforniaAges 18 years+ - NCT07493317RecruitingPhase 2
Tocilizumab for depression with inflammation
This trial tests a medication called tocilizumab, which targets inflammation, to see if it can improve symptoms of major depression in people with signs of inflammation. You may be eligible if you have depression with a high monocyte count and significant loss of interest or pleasure.
New York, New YorkAges 18–70 - NCT07493629Recruiting
Study on immune status and disease control in inflammatory airway diseases
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Ningbo, ZhejiangAges 18 years+ - NCT07494812Recruiting
Testing a new fluid drain method for normal pressure hydrocephalus
This study tests a new way to drain fluid from the spine during a lumbar drain trial for older adults with suspected normal pressure hydrocephalus. The goal is to see if using a special pressure-regulated system makes the procedure safer and more effective at predicting who will benefit from a shunt.
Dallas, TexasAges 60–99 - NCT07495761Recruiting
Central sensitization signs in adults with autism
This study looks at whether adults with autism (without intellectual disability) experience central sensitization, a condition where the nervous system becomes overly sensitive to stimuli. It aims to understand how common this is and why it matters for treatment.
Grenoble, IsereAges 18 years+ - NCT07495826Recruiting
Predicting behavior in kids during sedation
This study looks at children aged 1 to 17 who get sedation or anxiety medicine for a procedure in the emergency department or dental clinic. Researchers want to understand what predicts how children behave during and after sedation.
London, OntarioAges 1–17 - NCT07496021Recruiting
Probiotic for early Alzheimer's: safety and memory benefits
This trial tests a new probiotic (Lactococcus lactis CKDB001) to see if it can slow memory loss in people with early Alzheimer's. It’s a 12-week study that requires a positive amyloid PET scan and allows mild to moderate symptoms.
Gyeonggi-doAges 55–85 - NCT07496203Recruiting
BETY program after knee injections for osteoarthritis
This trial tests if a special exercise and education program called BETY helps people with knee osteoarthritis feel better after getting a knee injection. You may qualify if you had a knee injection in the last month and have moderate knee arthritis.
Ankara, SamanpazarıAges 18 years+ - NCT07496749Recruiting
Ketogenic diet for super-refractory seizure emergency
This trial tests if a high-fat, low-carb diet (ketogenic diet) can help stop seizures that have not responded to other treatments. It is for patients with a very severe, ongoing seizure emergency called super-refractory status epilepticus.
Hefei, AnhuiAges 14–80 - NCT07496853Recruiting
Arm support's effect on walking after stroke
This study looks at whether using a cane or other support for your affected arm can improve how you walk. If you had a stroke and have trouble using one side of your body, this trial may help find better ways to help you move safely.
AnkaraAges 18 years+ - NCT07496918RecruitingPhase 2
Brain effects of light and sound stimulation at 40 Hz
This study tests whether special lights and sounds (at a specific 'gamma' frequency) can safely affect brain activity. It is an early trial looking at how the brain responds to these gentle sensory stimulations.
Cambridge, MassachusettsAges 18–100 - NCT07497464Recruiting
Handedness test for stroke recovery
This trial tests if a simple, free task can recognize handedness in people who have had a stroke. It aims to help tailor rehabilitation after a stroke.
Madrid, MadridAges 18 years+ - NCT07497698Recruiting
Saffron supplement for better sleep in adults
This study tests whether taking a saffron extract supplement can help improve sleep in middle-aged adults with mild to moderate sleep troubles. You would take a daily supplement for a few weeks and report how well you sleep.
Granada, GranadaAges 18–65 - NCT07497867Recruiting
Long-term study of Korean CADASIL patients
This study follows people with CADASIL over time to learn more about the condition. It may help researchers understand how CADASIL progresses and improve care for patients.
Jeju City, Jeju-doAges 19 years+ - NCT07498296Recruiting
Adapting a home program and sleep tracking for Parkinson's
This trial tests a program to help people with Parkinson's disease exercise at home and improve sleep. It uses online coaching and a video device to see if it makes daily tasks easier.
Aurora, ColoradoAges 18 years+ - NCT07498491Recruiting
Weighted blanket study for adults with ongoing pain
This study tests whether using a weighted blanket (10–25 pounds) while sleeping can help adults with chronic pain. If you join, you'll use the blanket every night for about 5 weeks and complete simple online questionnaires.
Portland, OregonAges 18 years+ - NCT07498452Recruiting
Sleep behavior study for patients and their partners
This study looks at the needs of people with isolated REM sleep behavior disorder (iRBD) and the people close to them. It aims to understand how this condition affects daily life and relationships.
Bologna, Emilia-RomagnaAges Any age - NCT07498712Recruiting
Studying a probiotic for better sleep
This trial tests if a probiotic called Lactobacillus reuteri can improve sleep quality. Researchers want to see if taking this 'good bacteria' helps people who have mild to moderate sleep troubles feel more rested.
Seoul, YeongdeungpoAges 19–65 - NCT07499570Recruiting
Talk therapy using AI for older adults with memory issues
This study tests an AI-powered talk therapy for older adults with mild memory problems who live at home. It aims to reduce challenging behaviors like agitation, anxiety, or depression by delivering personalized support through a computer or tablet.
Indianapolis, IndianaAges 65 years+ - NCT07500116Recruiting
Home monitoring after minor stroke or TIA
This study tests whether using a wearable and smartphone app at home can help monitor recovery after a minor stroke or mini-stroke (TIA) – possibly reducing hospital stays while keeping you safe. If you have mild symptoms that stabilized in the ER, and you have help at home, you may qualify.
BarcelonaAges Any age - NCT07500727Recruiting
Exercise and muscle health in older adults with MS
This trial tests how exercise affects muscle health in people aged 60 or older with multiple sclerosis. It may help you understand if a structured exercise program can improve your strength and mobility.
Oklahoma City, OklahomaAges 60 years+ - NCT07500896Recruiting
Dance program for children with cerebral palsy
This study tests if a fun, rhythmic dance program can help children with cerebral palsy improve their learning skills. It compares the dance program to usual care to see if dancing helps with thinking and moving.
Toulouse, OccitanieAges 6–17 - NCT07501377Recruiting
Diet and brain health study for women in menopause with overweight
This trial tests whether a diet rich in fiber and plant compounds (polyphenols) can reduce brain inflammation in perimenopausal women who are overweight. If you're in early menopause and have some inflammation, this study may show how diet affects your brain health.
Leipzig, SaxonyAges 35–60 - NCT07501429RecruitingPhase 1
Shockwave therapy for arm spasticity after spinal cord injury
This trial tests whether shockwave therapy can reduce muscle tightness in the elbow and wrist caused by spinal cord injury. It may help make daily tasks like dressing or bathing easier.
West Orange, New JerseyAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.