Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,504 recruiting studies in this area right now.
By phase
- Not applicable9,843
- Phase 2785
- Phase 1574
- Phase 3532
- Phase 4345
- Phase 1/Phase 2306
- Phase 2/Phase 3119
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease342
- Multiple Sclerosis339
- Dementia229
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury155
- Spinal Cord Injuries151
- Sarcopenia150
- Acute Ischemic Stroke142
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota64
Where studies are running
- California677
- Massachusetts308
- New York294
- Florida278
- Texas270
- Maryland245
- Alabama214
- Arizona210
- Illinois193
- Pennsylvania177
Recruiting studies12,502 total
- NCT07537426Recruiting
Acupuncture for Dry Eyes After Facial Paralysis
This trial tests whether tiny acupuncture needles placed under the skin can help relieve dry eyes and other eye discomfort that develops after long-lasting facial paralysis. The goal is to see if this treatment can improve symptoms when standard care hasn't worked well enough.
Hangzhou, ZhejiangAges 18–65 - NCT07539025Recruiting
How the Spinal Cord Learns and Adapts
This study explores how your spinal cord can learn and change through repeated movements. Researchers will ask you to participate in up to 4 sessions to understand how the nervous system adapts, which may help improve treatments for spinal cord injuries in the future.
New York, New YorkAges 18–80 - NCT07539389Recruiting
Robot-Assisted Walking Training for Children With Cerebral Palsy
This study tests whether a robotic device called Bambini Kids can safely help children with cerebral palsy improve their walking and movement. The robot assists with gait training—guided walking practice—to see if it helps strengthen muscles and improve mobility.
Songpa, SeoulAges 2–10 - NCT07539441RecruitingPhase 1/Phase 2
Mirdametinib for brain and nervous system tumors
This trial tests a drug called mirdametinib for people with specific types of brain tumors or neurohistiocytosis (a rare condition affecting the nervous system). The drug targets mutations that cause these conditions to grow.
Basking Ridge, New JerseyAges 18 years+ - NCT07539740Recruiting
Brain Stimulation to Help Improve Consciousness After Brain Injury
This study tests whether a non-invasive brain stimulation technique called transcranial theta-burst stimulation (tTIs) can help patients recover consciousness after severe brain injury. The treatment aims to improve responsiveness in people in vegetative states or minimally conscious states.
Guangzhou, GuangdongAges 18–70 - NCT07539792RecruitingPhase 2
New Skull Support Plates for Pituitary Tumor Surgery
This study tests a new type of absorbable (dissolvable) support plate used during minimally invasive surgery to remove tumors in the pituitary gland area. The plate helps support the surgical site as it heals. Researchers want to see if this new plate works safely and effectively compared to standard approaches.
Foshan, GuangdongAges 1–80 - NCT07540117Recruiting
Social Prescribing to Improve Health in Older Adults
This study tests whether connecting older adults with community activities and exercise programs (like mindfulness and walking) can improve their overall health and quality of life. You'll participate in guided activities designed to keep you active and engaged in your community.
Zhunan, MiaoliAges 55 years+ - NCT07540572RecruitingPhase 1
Testing IDE574 safety and effectiveness in advanced solid tumors
This early-stage trial tests a new drug called IDE574 to see if it is safe and effective in treating advanced cancers that have spread or stopped responding to standard treatments. The trial focuses mainly on hormone-receptor positive breast cancer, but also includes lung, prostate, and colorectal cancers.
Plantation, FloridaAges 18–99 - NCT07540741Recruiting
PCSK9 Inhibitors for Large-Artery Stroke Recovery
This trial tests whether a cholesterol-lowering medication called evolocumab (a PCSK9 inhibitor) can help people recover better after a specific type of stroke caused by clogged arteries. The study checks if lowering cholesterol further than usual statins do improves stroke outcomes and is safe.
HeilongjiangAges 18–80 - NCT07541560Recruiting
Group Activities and Music for Stroke Recovery
This study tests whether group leisure activities and music training can help people recover better after a stroke. You would participate in these activities during your hospital stay in the first few weeks after your stroke.
Barcelona, CataloniaAges 18 years+ - NCT07541612Recruiting
Monitoring Spinal Cord Blood Flow During Aortic Surgery
This study tests a non-invasive monitoring device (NIRS) that tracks blood flow to the spinal cord during planned aortic surgery. The goal is to better understand and prevent spinal cord damage that can cause paralysis after major aortic procedures.
Naples, ItalyAges 18 years+ - NCT07542028Recruiting
Pain Relief Methods for Kidney Transplant Surgery
This study compares different pain management techniques during kidney transplant surgery. It aims to find the most effective way to control pain after your operation.
Altındağ, AnkaraAges 18–65 - NCT07542756RecruitingPhase 4
Testing Common Sleep Medications for Insomnia
This study compares how well different over-the-counter and prescription sleep medications work for insomnia. Researchers will guide you through trying medications one at a time to find what works best for your sleep problems.
Philadelphia, PennsylvaniaAges 18–80 - NCT07542834Recruiting
Virtual Reality Training for Medical Students
This study tests whether using virtual reality can help medical students learn better and feel more confident in their training. Researchers will compare how students learn with VR versus traditional methods.
Athens, OhioAges 18 years+ - NCT07543003Recruiting
Wearable Monitoring for Young Children With Spinal Muscular Atrophy
This study uses wearable devices (like smartwatches or activity trackers) to monitor movement and motor development in young children with spinal muscular atrophy (SMA), a rare genetic condition affecting muscle strength. The goal is to see if wearables can track disease progression and treatment response better than traditional clinic visits.
OxfordAges Up to 4 years - NCT07543016Recruiting
Amino Acids and Exercise for FSHD Muscle Weakness
This study tests whether amino acid supplements combined with exercise can help people with FSHD (a genetic muscle disease) build strength and reduce fatigue. Researchers will compare participants who receive amino acids plus exercise training to a control group.
Voghera, PaviaAges 18–50 - NCT07543367Recruiting
Brain implant to restore arm movement in ALS
This study tests a surgically implanted brain-computer interface (BCI)—a device that reads signals directly from your brain to help control a computer cursor or robotic arm. It's designed for people with ALS whose arms are paralyzed and who haven't responded to standard treatments.
Jacksonville, FloridaAges 22 years+ - NCT07543991RecruitingPhase 1
Gene therapy for giant axonal neuropathy via vagus nerve
This is a follow-up study for patients who previously received an experimental gene therapy (scAAV9/JeT-GAN) for giant axonal neuropathy (GAN), a rare genetic nerve disorder. The new treatment delivers the therapy directly into the vagus nerve—a major nerve in the neck—to help manage nerve damage and related symptoms.
Dallas, TexasAges 10–25 - NCT07544082Recruiting
Acupuncture for Insomnia Related to Heart-Spleen Imbalance
This study tests whether acupuncture using traditional five-point techniques can help people with long-term insomnia, especially those experiencing poor sleep quality, nightmares, and early morning awakening. It focuses on a specific pattern in traditional Chinese medicine called Heart-Spleen deficiency.
Ho Chi Minh CityAges 18 years+ - NCT07544303Recruiting
Fatigue and Mental Well-Being in MS Patients
This study explores how fatigue and mental health are connected in people with multiple sclerosis. Researchers will use audio sessions through headphones to understand your experiences and may help improve care for MS-related tiredness and mood.
VanAges 18–80 - NCT07544563Recruiting
Brain Activity During Sound Testing
This study measures how your brain responds to sounds in a specially designed quiet room. Researchers want to understand how epilepsy affects sound processing, which could help improve treatment in the future.
ParisAges 18 years+ - NCT07544875Recruiting
Brain Training Program for Adults in Hong Kong
This volunteer training program in Hong Kong teaches brain exercises and cognitive skills to adults age 50 and older. The program aims to help keep your mind sharp and may improve memory and thinking abilities.
Hong KongAges 50 years+ - NCT07545473Recruiting
Eye Imaging to Detect Brain Disease Markers
This study uses a special camera to photograph the back of your eye in detail. Researchers believe changes in the eye may reflect brain diseases like Alzheimer's or Parkinson's, and this imaging could help detect these conditions earlier.
Melbourne, VictoriaAges 30 years+ - NCT07546292Recruiting
Brain Stimulation to Improve Reading and Letter Learning
This study tests whether a safe, non-invasive brain stimulation technique can help improve how your brain learns letters and sounds, and how well you read. You'll receive mild electrical stimulation to your scalp while learning letter-sound pairs, and researchers will use MRI scans to see how your brain responds.
ZurichAges 18–35
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,504 recruiting neurology studies from the U.S. registry right now, out of 19,972 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.