Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,516 recruiting studies in this area right now.
By phase
- Not applicable9,855
- Phase 2786
- Phase 1573
- Phase 3533
- Phase 4344
- Phase 1/Phase 2305
- Phase 2/Phase 3120
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis340
- Dementia230
- Ischemic Stroke202
- Epilepsy197
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury156
- Spinal Cord Injuries152
- Sarcopenia151
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine112
- Pain Management112
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon80
- Johns Hopkins University71
- National Taiwan University Hospital71
- University of Minnesota65
Where studies are running
- California678
- Massachusetts307
- New York295
- Florida274
- Texas271
- Maryland245
- Alabama214
- Arizona209
- Illinois193
- Pennsylvania177
Recruiting studies12,514 total
- NCT06510634Enrolling by invitation
Stroke treatment after 24 hours for vertebrobasilar blockage
This trial tests a method to triage people who had a stroke in the back part of the brain (vertebrobasilar artery) more than 24 hours ago. The goal is to find the best way to decide which patients may still benefit from treatment.
Tianjin, Tianjin MunicipalityAges 18–90 - NCT06509776Enrolling by invitation
Bone growth and hormone health in young adults
This study looks at how bones mature and how hormones change as you become a young adult. If you were born in Denmark in 2006 or 2007 and are 18, you may be invited to help researchers understand these changes.
AalborgAges 18–19 - NCT06500039Enrolling by invitation
Positive Psychology Exercises for People With MS
This study looks at whether positive psychology exercises (activities that boost well-being) can help people with multiple sclerosis. You will use a smartphone app to complete short exercises over several weeks.
BoluAges 18–65 - NCT06495593Enrolling by invitationPhase 4
Ocrelizumab's effect on immune cells in lymph nodes in MS
This study tests how ocrelizumab, a medication for MS, affects immune cells in your lymph nodes. It may help doctors understand how the drug works and why it helps some people more than others.
San Francisco, CaliforniaAges 18–65 - NCT06492057Enrolling by invitation
EMS muscle training for astronauts in space
This trial tests if a special muscle stimulation device called EMS can help astronauts stay fit during spaceflight. It may prevent muscle loss in zero gravity.
Mitte, State of BerlinAges 40–60 - NCT06491927Enrolling by invitation
Long-term follow-up for RGX-202 in Duchenne muscular dystrophy
This long-term follow-up study watches people who previously received the experimental gene therapy RGX-202 for Duchenne muscular dystrophy. It checks how patients are doing over time and does not involve any new treatment.
Little Rock, ArkansasAges Any age - NCT06489561Enrolling by invitation
Brain activity study for epilepsy patients
This study looks at how your brain makes decisions. It involves pressing buttons on a laptop while your brain activity is recorded. The goal is to understand how the brain works in people with epilepsy.
Los Angeles, CaliforniaAges 18–65 - NCT06483165Enrolling by invitation
F.A.S.T. and BE FAST stroke signs study
This study asks the public to share how well they know the warning signs of stroke (using the F.A.S.T. or BE FAST mnemonic). It may help improve stroke awareness and save lives.
Dallas, TexasAges 19 years+ - NCT06478628Enrolling by invitation
Insomnia in pain rehabilitation patients
This trial looks at sleep problems in people going through pain rehabilitation. It aims to understand and possibly improve sleep in those with long-lasting pain.
RissaAges 18 years+ - NCT06476431Enrolling by invitation
Smartglasses walking training for stroke recovery
This trial tests whether walking while wearing smartglasses that show simple mental tasks can help stroke survivors improve their step and thinking coordination. It's for people who can walk on their own and have weakness on one side from a stroke.
Uijeongbu-si, Gyeonggi-doAges 20–80 - NCT06475365Enrolling by invitation
Salt water gargling after neck surgery to help swallowing
This study tests whether gargling with salt water after multi-level neck fusion surgery can improve swallowing recovery. If you are having this surgery, the trial aims to find a simple, low-cost way to protect your swallowing function.
Los Angeles, CaliforniaAges 18–80 - NCT06471309Enrolling by invitation
Theta burst TMS for swallowing problems after stroke
This trial tests a type of brain stimulation called theta burst transcranial magnetic stimulation (TMS) to see if it can help people who have trouble swallowing after a stroke. It is designed for people who had their first stroke within the last 2 weeks to 6 months and are right-handed.
Zhengzhou, HenanAges 18–80 - NCT06464835Enrolling by invitation
Brain stimulation and swallowing therapy for post-stroke swallowing problems
This trial tests whether combining two types of brain stimulation (iTBS and NMES) can improve swallowing problems after a stroke. If you have had trouble swallowing for at least two weeks but no longer than six months after your stroke, you may be able to join.
Zhengzhou, HenanAges 18–80 - NCT06460077Enrolling by invitation
Studying MS brain lesions with iron rims using advanced scans
This study uses advanced MRI and PET scans to look at certain types of MS brain lesions called 'slowly expanding lesions' that have an iron rim. The goal is to better understand how these lesions behave over time, which may help guide future treatments.
Turku, Southwest FinlandAges 18–80 - NCT06452173Enrolling by invitation
Risk prediction for stroke in carotid artery narrowing
This study uses MRI scans to build a risk prediction model for stroke and other cerebrovascular events in people with carotid artery stenosis (narrowing of the neck arteries). By participating, you help doctors better understand who is at highest risk, which may lead to more personalized treatment.
Beijing, Beijing MunicipalityAges Any age - NCT06451419Enrolling by invitation
Non-motor symptoms in GBA-related Parkinson's disease
This study looks at non-motor symptoms (like mood, thinking, or sleep problems) in people with a specific genetic change linked to Parkinson's disease. It compares those with the GBA gene change to those without it to see how symptoms differ.
Pozuelo de Alarcón, MadridAges 18 years+ - NCT06448065Enrolling by invitation
Reliability of gait classification in children with cerebral palsy
This study looks at how reliable (consistent) the way doctors classify walking patterns in children with spastic cerebral palsy is. It only uses existing walking data already collected at the Karolinska Hospital, so no new visits or tests are needed.
StockholmAges 3–18 - NCT06443996Enrolling by invitation
Sleep, mood, and colorectal cancer recovery study
This study looks at how your sleep quality and emotional well-being before surgery might affect your recovery from colorectal cancer. By filling out questionnaires, you help doctors learn whether these factors play a role in the cancer coming back.
ShanghaiAges 18–80 - NCT06443463Enrolling by invitationPhase 2
Long-term safety of BHV-7000 in epilepsy
This study checks the long-term safety of BHV-7000 for people who already completed an earlier trial with this drug. You keep taking the same medicine while doctors watch for any side effects over time.
Birmingham, AlabamaAges 18–75 - NCT06438679Enrolling by invitationPhase 4
3T therapy for MDA5-positive dermatomyositis with lung involvement
This trial tests a treatment called 3T therapy for people with MDA5-positive dermatomyositis, a rare autoimmune disease that affects the skin, muscles, and often the lungs. The goal is to see if 3T therapy can help control the disease and improve lung function.
Hangzhou, ZhejiangAges 18 years+ - NCT06434558Enrolling by invitation
MRI predictors of cryolysis for sleep apnea
This study uses MRI scans to see how well a cold treatment (cryolysis) works for obstructive sleep apnea. It is only open to people already in the ARCTIC-3 trial at the University of Pennsylvania.
Philadelphia, PennsylvaniaAges Any age - NCT06433622Enrolling by invitation
Platelet transfusion for severe brain injury on blood thinners
This trial tests whether giving a platelet transfusion to patients with severe traumatic brain injury who are on antiplatelet medication can improve how well their blood clots. You may qualify if you have a serious brain bleed and are taking a medication like aspirin or clopidogrel.
Lancaster, PennsylvaniaAges 18 years+ - NCT06431893Enrolling by invitationPhase 3
Long-term study of pegtibatinase for classical homocystinuria
This trial is a long-term follow-up study examining the safety and effectiveness of pegtibatinase for people with classical homocystinuria (HCU). It is open to those who have recently taken part in or finished the HARMONY or COMPOSE studies.
Phoenix, ArizonaAges 5–65 - NCT06431659Enrolling by invitation
Palliative care guide study at nursing homes
This study tests a guide to improve palliative care for nursing home residents. It focuses on making sure their wishes are respected and they receive appropriate support.
Stockholm, Region StockholmAges 65–130
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,516 recruiting neurology studies from the U.S. registry right now, out of 20,061 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.