Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,516 recruiting studies in this area right now.
By phase
- Not applicable9,855
- Phase 2786
- Phase 1573
- Phase 3533
- Phase 4344
- Phase 1/Phase 2305
- Phase 2/Phase 3120
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis340
- Dementia230
- Ischemic Stroke202
- Epilepsy197
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury156
- Spinal Cord Injuries152
- Sarcopenia151
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine112
- Pain Management112
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon80
- Johns Hopkins University71
- National Taiwan University Hospital71
- University of Minnesota65
Where studies are running
- California678
- Massachusetts307
- New York295
- Florida274
- Texas271
- Maryland245
- Alabama214
- Arizona209
- Illinois193
- Pennsylvania177
Recruiting studies12,514 total
- NCT06430918Enrolling by invitation
Nerve pain and sleep quality in knee osteoarthritis
This study looks at how nerve pain and sleep quality are related in people with knee osteoarthritis. It aims to help doctors better understand and treat pain.
IzmirAges 18–80 - NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT06429007Enrolling by invitationPhase 1
Metformin for infants after brain injury from HIE
This trial tests whether metformin, a common diabetes medicine, can help heal brain injury in infants who had HIE (lack of oxygen at birth) and were treated with cooling. It aims to see if the drug is safe and possible to give to babies between 3 and 6 months old.
Boston, MassachusettsAges 3 months–6 months - NCT06426602Enrolling by invitation
Brain communication trial for disorders of consciousness
This trial tests a new way to help people with disorders of consciousness (like locked-in syndrome) communicate using their brain activity. The goal is to see if a special system can unlock better communication for those who have limited ability to speak or move.
Pittsburgh, PennsylvaniaAges 16–65 - NCT06424041Enrolling by invitationPhase 2
Fecal transplant for fibromyalgia pain relief
This study tests whether transferring healthy gut bacteria from a donor can reduce pain in women with fibromyalgia. You would first take antibiotics and laxatives to prepare your gut, then receive the transplant through a colonoscopy.
Haifa, NorthAges 18–75 - NCT06421532Enrolling by invitationPhase 2
Testing LXB to clear protein buildup in CAA
This study tests whether the drug LXB (sodium oxybate) can help clear abnormal protein buildup in the brain's small blood vessels (CAA). Participants will take LXB nightly for 8 weeks and have MRIs and spinal taps to measure changes.
LeidenAges 30 years+ - NCT06412432Enrolling by invitation
Exercise and rehab for heart amyloidosis
This study tests whether a supervised exercise and rehabilitation program can help people with a specific type of heart amyloidosis (ATTRwt) feel better and improve their heart function. It may be a good fit if you have stable heart failure and can safely exercise.
NaplesAges 18 years+ - NCT06412328Enrolling by invitation
Psychoeducation for parents of children with DMD
This study offers a psychoeducation program for parents of children with Duchenne Muscular Dystrophy. It aims to provide support and education to help you care for your child.
Ankara, CankayaAges 18–65 - NCT06410859Enrolling by invitationPhase 2
Botox injection for trigeminal neuralgia pain
This study tests a Botox injection (HengLi®) to see if it can reduce facial pain from trigeminal neuralgia. It is for people whose pain is not well controlled by standard medications.
Beijing, Beijing MunicipalityAges 18–75 - NCT06405646Enrolling by invitation
Cannabidiol and Cannabinol for Chronic Jaw Muscle Pain
This study tests whether certain compounds from the cannabis plant (CBD and CBN) can help relieve long-term pain in the jaw muscles. It is for adults with chronic orofacial pain who have not recently taken medications that affect the nerves or muscles.
WroclawAges 18–80 - NCT06398366Enrolling by invitation
Heart tests to prevent another stroke
This study looks at how heart problems might cause strokes. If you had a stroke that doctors can't explain after many tests, this trial will do extra heart monitoring to find possible causes and help prevent another stroke.
Camden, New JerseyAges 18 years+ - NCT06394778Enrolling by invitation
Brain waves during surgery in older adults
This study looks at brain wave patterns during surgery in older adults to better understand and predict confusion after surgery. If you are 60 or older and having joint or spine surgery, you may be able to help.
Hangzhou, ZhejiangAges 60 years+ - NCT06391294Enrolling by invitation
Brain stimulation study for language mapping during awake surgery
This study uses gentle electrical stimulation on the brain during awake surgery to understand how language works. It's for people having brain tumor removal or epilepsy monitoring who can speak English and do not have serious speech or thinking problems.
Chicago, IllinoisAges 18–80 - NCT06379594Enrolling by invitation
Remote brain health clinic for mild memory problems
This study tests a remote 'brain health clinic' for people with mild memory or thinking problems (mild cognitive impairment). It aims to help diagnose the cause of memory issues from home, so you don't need to travel to a clinic.
London, Denmark HillAges 18 years+ - NCT06378554Enrolling by invitation
Cereset study for stress and performance in nurses
This study tests whether a new brain-calming technique called Cereset can help healthcare workers on the Orthopedic Trauma Unit feel less stressed and perform better. You would sit in a chair and listen to gentle sounds that help your brain relax.
Winston-Salem, North CarolinaAges 18–100 - NCT06377085Enrolling by invitationPhase 1
Testing an old drug for tight muscles in kids with cerebral palsy
This trial tests a drug called 5-Azacytidine, which is being used in a new way—to help loosen tight muscles (contractures) in children with cerebral palsy. It aims to see if it can reduce the need for surgery.
San Diego, CaliforniaAges 2–18 - NCT06376279Enrolling by invitation
Genetic testing for metabolic diseases
This trial uses genetic testing to find the cause of suspected metabolic diseases, including some cases of epilepsy. It may help you get a clearer diagnosis and guide treatment.
Ages Any age - NCT06375993Enrolling by invitationPhase 1
Prula-cel for autoimmune diseases: a phase 1 study
This trial tests a new treatment called prulacabtagene leucel (prula-cel), which is a type of immune cell therapy (CAR T-cells) for people with certain autoimmune diseases. It aims to see if it can reset the immune system and reduce disease activity in conditions like lupus, scleroderma, vasculitis, or myositis.
Redwood City, CaliforniaAges 18–80 - NCT06369571Enrolling by invitationPhase 1/Phase 2
Improving heart health in adults with epilepsy on a modified Atkins diet
This study tests whether a statin medication (atorvastatin) can help lower cholesterol and improve heart health in adults with epilepsy who have been on a modified Atkins diet for a year or more. It may be a good fit if you have high cholesterol and are not already on a statin or have had heart problems.
Baltimore, MarylandAges 18 years+ - NCT06364293Enrolling by invitation
Predicting outcomes after aneurysm treatment
This study looks at people who have had a brain aneurysm treated with a minimally invasive procedure. Researchers want to see if they can predict who might have a worse outcome later, using follow-up images.
BeijingAges 18–80 - NCT06363526Enrolling by invitation
Digital breathing exercises for children with muscular dystrophy
This trial tests a 5-week digital breathing exercise program for children with Duchenne or Becker muscular dystrophy. It aims to improve lung function using simple exercises done at home.
MálagaAges 5–20 - NCT06355102Enrolling by invitation
Study of tinnitus after sudden hearing loss using brain scans
This study uses brain imaging (fMRI) and blood tests to understand why some people with sudden hearing loss develop tinnitus (ringing in the ears) while others do not. It may help researchers find better ways to prevent or treat tinnitus.
Nanjing, JiangsuAges 18–65 - NCT06351111Enrolling by invitation
Vagus nerve stimulation for spinal cord injury follow-on study
This study tests whether vagus nerve stimulation can help people with spinal cord injury improve arm, leg, bladder, or sensory function. You must have completed an earlier phase of this research to join.
Dallas, TexasAges 18–64 - NCT06349538Enrolling by invitation
Essential tremor subtypes and progression markers study
This study looks for biological markers to better understand different types of essential tremor and how the condition changes over time. It may help identify who has which subtype and predict disease progression.
Graz, AustriaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,516 recruiting neurology studies from the U.S. registry right now, out of 20,061 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.