Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT06073990Enrolling by invitation
Insomnia help for adults 50 and older
This trial tests a short talk therapy that helps improve sleep without medication. It focuses on older adults who have had trouble sleeping for at least 3 months.
Tainan, TaiwanAges 50 years+ - NCT07101991Recruiting
Targeted fluid management during brain surgery
This study tests whether using a non-invasive monitor to guide fluid and medication during planned brain surgery helps keep your blood pressure and heart rate stable. It may help reduce complications during and after surgery.
BrnoAges 18 years+ - NCT07643896Recruiting
Blood test for pregnancy risk assessment using fetal cells
This study tests a new blood test that looks for fetal cells in your bloodstream to check your baby's health during pregnancy. The test is non-invasive—just a regular blood draw—and aims to help identify pregnancy risks earlier than traditional methods.
Phoenix, ArizonaAges Any age - NCT05588167Recruiting
Niemann-Pick type C patient database and genetic data study
This study collects health information and genetic samples from people diagnosed with Niemann-Pick disease type C. The goal is to build a large database that can help researchers better understand the condition and improve future care.
Bethesda, MarylandAges 3 months+ - NCT07138560RecruitingPhase 4
Study of IPX-203 for Parkinson's disease (BOOST-PD)
This study tests a new formulation of carbidopa-levodopa (IPX-203) to see how well it works for people with Parkinson's disease. It uses a wearable device to measure movement and aims to improve “off” time, when symptoms return between doses.
Cleveland, OhioAges 40 years+ - NCT05938543Recruiting
Brain stimulation and appetite in Prader-Willi syndrome
This trial studies whether targeted brain stimulation (TMS) can help with appetite and eating feelings in people with Prader-Willi syndrome. It also includes an MRI scan to measure brain-related effects, but only if you can safely have these scans.
Belmont, MassachusettsAges 18–64 - NCT06586320Enrolling by invitation
Eye movement test for Parkinson's and Essential tremor
This study uses a simple eye movement test to see if it can help tell the difference between Parkinson's disease, Essential tremor, and healthy people. The goal is to find a better way to diagnose and track these conditions.
Manchester, New HampshireAges 18 years+ - NCT07177352RecruitingPhase 3
Screening for Roche Alzheimer's studies
This is a screening study to find people who might be eligible for other Alzheimer's drug studies run by the same company. It helps match you to a treatment trial if you qualify.
Birmingham, AlabamaAges 50–90 - NCT05563792Recruiting
Non-drug options for managing chronic pain
This study tests non-drug treatments for chronic pain in the back, neck, or joints. It aims to help people manage pain and improve daily function without relying on medications.
Indianapolis, IndianaAges 18 years+ - NCT07749170Recruiting
Stroke treatment for blockages in smaller brain arteries
This study looks at how well a special catheter system works to remove blood clots from smaller arteries in the brain after a stroke. It aims to see if this treatment helps people recover better.
Englewood, ColoradoAges 18 years+ - NCT05286151Recruiting
Studying brain connectivity and timing in stuttering and nonstuttering teens
This study looks at how brain “networks” connect and how timing works in adolescents who stutter compared with those who don’t. It may help researchers better understand what underlies stuttering and how it differs from typical speech timing.
Ann Arbor, MichiganAges 9–13 - NCT06154252RecruitingPhase 2/Phase 3
Study of CABA-201 for active myositis in adults and children
This trial tests a new treatment called CABA-201, which uses your own immune cells modified to attack the overactive cells causing myositis. It is for people with active disease that hasn't improved enough with standard therapies.
Orange, CaliforniaAges 6–75 - NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Scottsdale, ArizonaAges 41–81 - NCT05990426Recruiting
Alternate day fasting during chemo for gynecologic cancers
This trial tests whether alternating between a fasting day and a normal eating day can help people recovering from gynecologic cancer surgery while they receive chemotherapy. It aims to see if this eating pattern is safe and helpful during treatment.
Chicago, IllinoisAges 18 years+ - NCT05872191Enrolling by invitation
Spanish-language tests for arm function after stroke
This study checks whether two hand/arm assessment questionnaires and tests work well in Spanish for people living with stroke-related arm weakness. It mainly involves you doing standardized assessments if you’re eligible.
Valencia, ValenciaAges 18–80 - NCT02889016Recruiting
Markers study for children with PANS and healthy controls
This study looks at physical, immune, and brain-related “markers” in children with PANS and compares them with healthy children. It may help doctors understand what is happening in PANS and how to recognize it more clearly early on.
Palo Alto, CaliforniaAges 4–18 - NCT03042026Recruiting
Testing a simple system to recognize acromegaly
This study tests a simple recognition tool to help tell whether someone has acromegaly or not. It may be useful for faster, easier identification of the condition.
TaipeiAges 20–80 - NCT03131427Recruiting
Registry for inherited liver and metabolism-related conditions
This is a study that collects health information and samples (if applicable) from people with certain genetic or metabolic liver diseases. It may help doctors better understand these conditions and improve future care.
Beijing, Beijing MunicipalityAges Any age - NCT02420067Recruiting
Screening for inner-ear tumors in people with Von Hippel-Lindau
This trial focuses on checking whether a specific inner-ear tumor (called an endolymphatic sac tumor) can be found earlier in people with Von Hippel-Lindau (vHL) disease. It may help doctors detect problems sooner so you can discuss treatment options earlier, if needed.
Copenhagen, Copenhagen NAges 15 years+ - NCT03152630Recruiting
Vascular dementia check-up and risk diagnosis study
This study aims to find early ways to diagnose “vascular dementia,” which happens when blood vessel problems affect thinking and memory. It may help by testing how well certain health risk factors and medical information can predict who might be developing it.
TaipeiAges 65 years+ - NCT02701036Recruiting
Natural history study for adult-onset progressive ataxia
This study follows people with progressive balance and coordination problems that started after age 40. The goal is to better understand what happens over time, which can help future treatments be developed for similar conditions.
InnsbruckAges 40 years+ - NCT02060695Recruiting
Study links Parkinson symptom ups and downs over time
This study looks at how changes in movement symptoms and non-movement symptoms happen together in people with early Parkinson disease. It may help doctors better understand what triggers symptom “ups and downs” and how to time treatment or monitoring.
SeoulAges Any age - NCT02440763Recruiting
Study of inherited progressive balance and coordination changes
This is a natural history study that follows people with inherited forms of “ataxia” (problems with balance and coordination) over time. It may help researchers better understand how these conditions progress in daily life and can inform future treatments.
InnsbruckAges 18 years+ - NCT02399748Recruiting
Long-term study of outcomes in Pompe disease
This study follows people with Pompe disease over a long period to learn how they do over time, especially those receiving enzyme replacement therapy. Your results could help doctors better understand expected outcomes and refine care.
TaipeiAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.