Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT03222375Recruiting
Home treatment for autism using special sound and imaging devices
This trial studies a home-based treatment for autism (or related conditions) using specially designed sound, image, and electromagnetic devices. It aims to see whether this personalized “treatment code” and device approach can improve autism-related skills and behaviors.
Louisville, KentuckyAges 1 month–21 years - NCT03416114Recruiting
Registry for people with rare primary headache types
This trial is a registry that collects information about rare types of primary headaches in specialized Italian headache clinics. It may help researchers better understand these conditions and improve future care.
FlorenceAges Any age - NCT03508986Recruiting
Parkinson’s family registry for people with Parkinson’s
This trial is a research registry that collects health and family information from people with Parkinson’s disease (and sometimes their close relatives). It may help doctors better understand how Parkinson’s runs in families.
Changsha, HunanAges Any age - NCT03508960Recruiting
Parkinson’s disease registry for people with early onset
This study is a registry that collects information from people with Parkinson’s disease (PD) to better understand the condition, especially in people whose symptoms started by age 50. It may help researchers learn which factors matter most for early-onset PD.
Changsha, HunanAges Up to 50 years - NCT03523104Recruiting
Registry for Parkinson’s with LRRK2 gene variants
This study is a registry that collects information from people with Parkinson’s who have specific LRRK2 gene changes. It helps researchers understand how this genetic form of Parkinson’s behaves over time.
Changsha, HunanAges Any age - NCT03523052Recruiting
People with Parkinson’s and SNCA gene changes
This registry study enrolls people who have Parkinson’s disease and carry certain SNCA gene changes. It aims to better understand how these genetic changes relate to Parkinson’s, which can guide future research and care.
Changsha, HunanAges Any age - NCT03523065Recruiting
Parkinson’s registry for people with GBA gene changes
This registry collects information about people with Parkinson’s who have specific changes in the GBA gene. The goal is to better understand how these gene changes affect Parkinson’s and support future research.
Changsha, HunanAges Any age - NCT03569735Recruiting
Elderly health survey in Nanshan, Shenzhen
This study follows people age 65 and older in Nanshan to learn about health over time using surveys and health samples. It may help researchers understand what supports healthy aging in the community.
Shenzhen, GuangdongAges 65 years+ - NCT03014687RecruitingPhase 4
Preventing sinus symptoms after pituitary surgery with antibiotics
This trial studies whether taking antibiotic medicine by mouth after endoscopic pituitary surgery can reduce post-surgery sinus and nasal symptoms. It may help people recover more comfortably and improve specific nasal outcome scores.
Phoenix, ArizonaAges 18–84 - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT03495024RecruitingPhase 4
Varenicline for quitting smoking in people with schizophrenia
This trial tests whether varenicline helps people with schizophrenia or schizoaffective disorder stop smoking. It also looks at related nervous-system side effects that can happen with some anti-psychotic medicines.
Philadelphia, PennsylvaniaAges 18–75 - NCT03992625Recruiting
Deep brain stimulation study for Parkinson’s, tremor, or dystonia
This trial studies outcomes after deep brain stimulation (a treatment that uses implanted electrodes) for people with Parkinson’s disease, essential tremor, or dystonia. It may help doctors understand who benefits most and how outcomes change after treatment.
St Louis, MissouriAges Any age - NCT03934957Recruiting
Study of health in people living in Hamburg
This study follows adults living in Hamburg to better understand health and health-related factors over time. You may help researchers learn what influences health in this age group.
HamburgAges 45–74 - NCT02760108Recruiting
Parkinson’s Families Project for people with family links
This project is for people age 16 and older who have Parkinson’s (or similar symptoms called parkinsonism). It focuses on people with a family history and/or symptoms that started before age 45, to better understand Parkinson’s in families.
LondonAges 16 years+ - NCT02423395RecruitingPhase 3
Orphenadrine for muscle cramps in people with cirrhosis
This trial tests whether orphenadrine (a medication used to reduce muscle cramping) can lessen muscle cramps in people who have cirrhosis of the liver. It may help if your cramps happen often, but you must avoid certain medication conflicts and health situations.
TantaAges Any age - NCT03470467Recruiting
ICU study of a reversible brain swelling condition
This trial looks at Posterior Reversible Encephalopathy Syndrome (PRES) in adults in the ICU. It may help doctors better understand and manage a condition that can cause seizures, confusion, headaches, and vision problems, and that typically shows specific changes on brain scans.
Le ChesnayAges 18 years+ - NCT04023656Recruiting
Study of prognosis in people with paroxysmal kinesigenic choreoathetosis
This study looks at how paroxysmal kinesigenic choreoathetosis (PKC) typically progresses over time in people in Korea. It may help doctors better predict outcomes and plan care. You may be asked about your diagnosis and results from brain and brain-wave tests.
SeoulAges 18 years+ - NCT04012658Recruiting
Study of people with Wilson disease genes and family members
This study follows people who have the genetic cause of Wilson disease, including people who feel well and family members. Researchers want to better understand Wilson disease and what to watch for over time.
FuzhouAges Any age - NCT04076449Recruiting
MRI measurements for epilepsy from a single brain blood vessel lump
This study uses special MRI scans to measure brain changes in people whose seizures are related to one cerebral cavernous malformation (a type of abnormal blood vessel in the brain). It aims to find a measurable “biomarker” from MRI that may help understand the epilepsy and the brain structure around it.
Beijing, Beijing MunicipalityAges 18–70 - NCT04010201Recruiting
Study of brain calcium deposits on CT scans
This study looks at people who have extra calcium deposits in the brain seen on a CT scan (and also includes some relatives and healthy volunteers). It aims to better understand who has brain calcification and what it may mean, using research visits and scan-based measurements.
Fuzhou, FujianAges Any age - NCT03856034Recruiting
Open vs minimally invasive surgery for spina bifida baby
This study compares two ways to correct spina bifida while the baby is still in the womb: an open operation (laparotomy) versus a minimally invasive endoscopic approach (percutaneous endoscopic). The goal is to see which approach leads to better outcomes for the baby and pregnancy.
Los Angeles, CaliforniaAges 18 years+ - NCT04010604Recruiting
Study of spinal muscular atrophy in patients and carriers
This is a long-term observation study that follows people affected by spinal muscular atrophy (SMA), people who carry the SMA gene but have no symptoms, and families of people with SMA. It helps researchers better understand SMA and related genetic status, which can support future treatment planning.
Fuzhou, FujianAges 1 week–70 years - NCT04144439RecruitingPhase 4
GABA treatment for ADHD and seizures in children with epilepsy
This trial studies whether adding GABA (a substance that affects brain signaling) can help children who have both epilepsy (seizures) and ADHD. If it works, it may reduce symptoms related to either seizures, ADHD, or both.
TantaAges 4–18 - NCT04161053RecruitingPhase 3
Nitazoxanide to prevent repeat liver brain episodes
This Phase 3 trial tests whether nitazoxanide can help stop hepatic encephalopathy (a “liver-to-brain” confusion problem) from coming back. It’s for adults with cirrhosis who have had at least one past episode, aiming to improve safety and prevent recurrence.
TantaAges 20–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.