Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT07662837Recruiting
Comparing Tai Chi and Qi Gong for Early Parkinson's
This study compares two gentle mind-body exercises, Tai Chi and Qi Gong, to see which one better helps people with early-stage Parkinson's disease. If you are between 50 and 65 and have stable medication, you may join to find out if these practices can improve your balance, movement, and well-being.
Lahore, Punjab ProvinceAges 50–65 - NCT06846281RecruitingPhase 3
Remibrutinib for relapsing multiple sclerosis after switching from Ocrevus
This study tests a new oral medication called remibrutinib for people with relapsing multiple sclerosis who are currently on Ocrevus. Participants will switch from Ocrevus to remibrutinib to see if it is safe and effective.
Scottsdale, ArizonaAges 40–70 - NCT07787741Recruiting
Cervical Epidural Injection for Chronic Neck Pain
This study tests a cervical epidural block (an injection into the neck area) as a treatment for chronic neck pain. It aims to see if this injection can help reduce pain in people with nerve-related neck pain.
Adapazarı, SakaryaAges 18–55 - NCT07788638Recruiting
Neurofeedback training for tinnitus relief
This study tests a non-invasive brain training method called neurofeedback to help reduce the distress caused by tinnitus, which is a constant ringing or buzzing in the ears. If you have bothersome tinnitus, this treatment might help you feel better.
Urbana, IllinoisAges 18–70 - NCT07125027Recruiting
Exercise and mindfulness for sciatica pain
This study tests a program called Move-MORE that combines exercise and mindfulness to help people with nerve-related leg pain (sciatica) that has lasted at least 3 months. You would use the program at home, attend weekly video sessions for 8 weeks, and complete questionnaires and daily surveys to see if the program improves your pain and quality of life.
Portland, OregonAges 18–75 - NCT07786649Recruiting
Non-invasive brain stimulation for stroke recovery
This trial tests different types of non-invasive brain stimulation to see which one helps people recover better from stroke-related problems like arm weakness, leg weakness, neglect, or speaking difficulty.
SingaporeAges 21–80 - NCT06557512Recruiting
Focused radiation after surgery for certain meningiomas
This study tests a type of focused radiation therapy (called stereotactic radiosurgery) given after surgery for certain meningiomas. The goal is to see if this treatment helps prevent the tumor from coming back, and to check its safety.
San Francisco, CaliforniaAges 18 years+ - NCT06651567RecruitingPhase 2
Study of a new drug for agitation in Alzheimer's disease
This study tests an experimental medication, ITI-1284, to see if it can safely reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, aggression, or irritability, and this drug aims to help manage those symptoms.
Anaheim, CaliforniaAges 55 years+ - NCT07787312Recruiting
Ultrasound for swallowing and muscle loss in intensive care patients
This study uses ultrasound to check the muscles that help you swallow and move. It aims to see if measuring these muscles can predict swallowing problems and muscle loss after being on a breathing machine.
Madrid, MadridAges 18 years+ - NCT07787247Recruiting
Remote monitoring for myasthenia gravis patients
This study tests whether remote monitoring through smartphone apps can effectively track myasthenia gravis symptoms and help manage care from home, instead of frequent in-person visits.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06891716RecruitingEarly Phase 1
PET scan for TDP-43 proteinopathies
This study tests a new PET scan dye that may help see TDP-43 protein buildup in the brain, which is linked to certain dementias and ALS. It aims to improve diagnosis and tracking of these conditions.
AmsterdamAges 40–70 - NCT07554924RecruitingPhase 1/Phase 2
Gene therapy for newly diagnosed spinal muscular atrophy type I infants
This study tests SKG0201, a new gene therapy designed to treat spinal muscular atrophy type I (SMA type I), a rare genetic condition affecting muscle strength. The trial enrolls very young infants diagnosed with SMA type I to see if the treatment is safe and helps improve muscle function.
Beijing, Beijing MunicipalityAges Up to 6 months - NCT05096273Recruiting
Training for control and expectations in PNES therapy
This study tests a treatment approach that aims to improve a sense of control and change symptom expectations for children or teens with psychogenic non-epileptic seizures (PNES). It also involves family support so the treatment fits your home life and goals.
Birmingham, AlabamaAges 11–18 - NCT06920004RecruitingPhase 3
Testing empasiprubart vs IVIg for chronic CIDP
This study tests an investigational drug called empasiprubart against standard IVIg in adults with CIDP. The goal is to see if it is safer and more effective for people who still have symptoms despite IVIg therapy.
Birmingham, AlabamaAges 18 years+ - NCT02991690Recruiting
Cooling treatment for acute neck spinal cord injury
This trial tests whether lowering your body temperature soon after a neck spinal cord injury can improve recovery. It is meant for certain types of spinal cord damage and looks at patients who can safely start cooling within 24 hours.
Phoenix, ArizonaAges 18–70 - NCT07011745RecruitingPhase 3
Study of KarXT for Alzheimer's Agitation
This study tests a new drug combination (KarXT + KarX-EC) to see if it can safely reduce agitation in people with Alzheimer's disease. It may help if you or your loved one has bothersome agitation that affects daily life.
Chandler, ArizonaAges 55–90 - NCT00575081Recruiting
Brain mapping during stereotactic procedures
This study builds a “brain atlas” by collecting information during stereotactic brain procedures. It may help doctors better plan and understand these brain procedures in the future.
Nashville, TennesseeAges 6–90 - NCT06290141RecruitingPhase 3
Testing riliprubart vs. standard IVIg for CIDP
This trial tests whether a new medication called riliprubart works as well as the usual IVIg treatment for people with chronic inflammatory demyelinating polyneuropathy (CIDP). It may offer another option for managing your condition.
Homewood, AlabamaAges 18 years+ - NCT07784192Recruiting
Nerve block versus spinal morphine for hip surgery pain
This study compares two ways to manage pain after hip surgery: a nerve block (a numbing injection near the hip) versus a spinal injection of morphine. The goal is to see which method provides better pain relief and fewer side effects.
Konya, SelcukluAges 18–65 - NCT07251088Recruiting
App and support for dementia family caregivers
This trial tests a program that uses an app and a care partner to help family members caring for someone with dementia. It aims to make caregiving easier and less stressful.
Karlsruhe, Baden-WurttembergAges Any age - NCT07188285Enrolling by invitation
Immune system study for active autoimmune diseases
This study uses a blood test called mass spectrometry to look at the immune system in people with active autoimmune diseases. It aims to find patterns that could help doctors better understand and treat these conditions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05350332Recruiting
Testing how lung air volume affects airway narrowing during sleep testing
This study looks at whether changing lung air volume affects how open or blocked your upper airway is during a drug-induced sleep test (DISE). It may help guide surgical choices for people with obstructive sleep apnea (OSA).
Atlanta, GeorgiaAges 18 years+ - NCT06066853RecruitingEarly Phase 1
MDMA plus therapy for fibromyalgia pain
This trial tests whether MDMA (a drug sometimes called 'ecstasy') can help people with fibromyalgia when used alongside therapy sessions. The goal is to see if it reduces pain and improves quality of life.
Charlestown, MassachusettsAges 21–65 - NCT07661901Recruiting
Reward sensitivity app for teens with suicidal thoughts
This trial tests a smartphone-based program designed to help teens who have had recent thoughts of suicide. It aims to see if the app can reduce suicide risk by boosting sensitivity to rewards in daily life.
Philadelphia, PennsylvaniaAges 13–17
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.