Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2781
- Phase 1578
- Phase 3536
- Phase 4343
- Phase 1/Phase 2306
- Phase 2/Phase 3123
Top conditions
- Stroke841
- Parkinson Disease429
- Multiple Sclerosis345
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke137
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida273
- Texas268
- Maryland246
- Arizona214
- Alabama210
- Illinois189
- Pennsylvania175
Recruiting studies12,405 total
- NCT06261502RecruitingPhase 2
CBD for Anxiety in Fragile X Syndrome
This trial tests if cannabidiol (CBD) can help with anxiety and improve brain function in people with Fragile X syndrome. Participants will receive CBD or a placebo, and may have brain scans (MRI) or magnetic stimulation (TMS) to see how it works.
Sherbrooke, QuebecAges 7–40 - NCT07110376Recruiting
Brain recordings during sleep with deep brain stimulation for Parkinson's
This study looks at brain activity during sleep in people with Parkinson's who have a deep brain stimulation (DBS) device. It aims to understand how different DBS settings affect sleep, which may help improve treatment.
Cleveland, OhioAges 18 years+ - NCT05104710RecruitingTeam says not enrolling
Testing brain–muscle coordination as a marker in ALS
This study measures how well your nerves and muscles work together to see if it can serve as an early sign (a “biomarker”) of ALS. It may help doctors track ALS more accurately, especially in people who already seem to have ALS based on nerve testing.
Irvine, CaliforniaAges 20–90 - NCT05301140RecruitingTeam says not enrolling
Registry study for paired VNS after stroke
This study follows people who already have the Vivistim device implanted after an ischemic stroke affecting arm or hand function. It may help researchers better understand how paired nerve stimulation therapy works in real-world care.
Orlando, FloridaAges 22 years+ - NCT05183152RecruitingTeam says not enrolling
Non-invasive brain signal control for assistive devices
This study tests an assistive device that you control using signals from the brain and muscles without surgery. It may help people with movement problems communicate or operate devices using gentle, non-invasive sensing.
Austin, TexasAges 18–80 - NCT06463587RecruitingTeam says not enrollingPhase 3
Oral cladribine for generalized myasthenia gravis
This study tests a new oral medication (cladribine) to see if it can reduce muscle weakness and daily symptoms in people with generalized myasthenia gravis. It compares the drug to a placebo (a pill with no active medicine) to check safety and effectiveness.
Phoenix, ArizonaAges 18 years+ - NCT05183165RecruitingTeam says not enrolling
Study measures copper levels in breast milk for Wilson’s disease
This study measures how much copper is present in breast milk in people with Wilson’s disease. It aims to provide safer guidance for breastfeeding during treatment, including during pregnancy.
ParisAges 18 years+ - NCT07790744Recruiting
Brain imaging study for early Parkinson's signs in people with REM sleep disorder
This study uses MRI scans to look at the brain in people with REM sleep behavior disorder (RBD), a condition that can be an early sign of Parkinson's disease. By comparing them with healthy volunteers, researchers hope to find early markers of Parkinson's that could lead to earlier diagnosis and treatment.
HvidovreAges 18 years+ - NCT07789535Recruiting
Sleep study for people with high blood pressure and poor sleep
This study looks at how improving sleep might affect blood vessel health in people with high blood pressure who don't sleep well. You might join if you have high blood pressure and poor sleep quality.
Guimarães, Braga DistrictAges 18–70 - NCT07657377Recruiting
Physical therapy for migraine relief
This trial tests whether physiotherapy (physical therapy) can help reduce migraine symptoms. It focuses on people diagnosed with migraine by a neurologist, excluding those with other headache types or certain health conditions.
AnkaraAges 18–55 - NCT07220005Recruiting
Ultrasound brain stimulation for arm weakness after stroke
This study tests a new non-invasive therapy using low-intensity focused ultrasound to stimulate the brain area affected by a stroke, which may help improve arm weakness in people who have had a stroke more than 6 months ago.
Durham, North CarolinaAges 21 years+ - NCT07789288Recruiting
Hard collar use after cervical spine fusion
This study compares recovery outcomes with and without a hard cervical collar after posterior cervical fusion surgery. You may qualify if you have degenerative disk disease and are scheduled for this type of spine surgery.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07677137Recruiting
Study of a new nerve stimulation device for chronic cluster headache prevention
This study is testing a new device that uses mild electrical stimulation near the back of the head to prevent cluster headaches. It is for people with chronic cluster headaches that are hard to treat with standard medicines.
Sint-NiklaasAges 22–70 - NCT07674654RecruitingPhase 3
Long-term safety study of an investigational migraine medication
This study is testing the long-term safety of an investigational migraine medication called elismetrep. It is for people who have already completed a previous study of this drug and are willing to continue using a smartphone app to track their symptoms daily.
Birmingham, AlabamaAges 18 years+ - NCT07789665Recruiting
Auditory nerve implant for deaf adults who cannot use cochlear implants
This study is testing a new way to use an inner ear implant (called an auditory nerve implant, or ANI) to help people who are deaf in both ears and cannot use a cochlear implant. The researchers want to see how well people perceive sounds with this device.
HanoverAges 18–85 - NCT07788859Recruiting
Testing dual-task walking tests in multiple sclerosis
This study looks at how well three different dual-task tests (doing two things at once while walking) work for people with multiple sclerosis. It aims to find reliable and valid ways to assess walking and thinking in MS.
GaziantepAges 18–65 - NCT06843356Recruiting
Endovascular treatment for worsening mild stroke with basilar artery blockage
This trial tests a procedure to open a blocked artery in the back of the brain (basilar artery) for people who had a mild stroke that later got worse. If you are eligible, you may receive this treatment up to 24 hours after your symptoms worsen.
Wuhu, AnhuiAges 18 years+ - NCT07560956Enrolling by invitation
Quality of Life in Adults With Untreated Fabry Disease
This study looks at how Fabry disease affects daily life in adults who haven't started treatment yet. Researchers want to understand your experiences and challenges to improve care for people with this rare genetic condition.
GothenburgAges 18 years+ - NCT06993142Recruiting
Slowing Parkinson's Early With Exercise
This trial tests whether a specific exercise program can slow the early stages of Parkinson's disease in people who have a genetic risk (LRRK2 or GBA variants). You will use a smartphone app to guide your exercise from home.
Rochester, New YorkAges 50 years+ - NCT05107635Recruiting
Registry for people treated with AtriCure for IST or POTS
This registry collects information from people who are getting—or already had—treatment for IST or POTS using an AtriCure device. It helps researchers better understand outcomes and safety in real-world care.
Loma Linda, CaliforniaAges 18–100 - NCT07325175Recruiting
Brain study to improve treatment for childhood dystonia
This study measures brain signals in children with dystonia to understand how the brain controls movement, with the goal of improving treatments like Deep Brain Stimulation (DBS). It also uses healthy children for comparison.
Cincinnati, OhioAges 6–21 - NCT07213700Recruiting
Long-term study on Alzheimer's disease
This study follows people who are either being evaluated for Alzheimer's disease or have already been diagnosed. Researchers want to track their health over many years to better understand the disease and how treatments affect it.
GrazAges Any age - NCT07399496Recruiting
Fast TMS for apathy in Parkinson's disease
This study tests a faster version of TMS (transcranial magnetic stimulation) to see if it can help with apathy—low motivation and lack of interest—in people with Parkinson's disease. You will receive several TMS sessions each day over a short period, and the study team will check if your mood and motivation improve.
Charleston, South CarolinaAges 45–85 - NCT07484555Recruiting
Posture rehab for vision problems in forward head posture
This study tests whether special posture exercises can improve mild vision problems in people with forward head posture. It may help if you're a young adult with this posture and some blurry vision.
Islamabad, CapitalAges 18–30
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,231 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.