Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06830421RecruitingPhase 3
High-dose chemo with stem cell transplant vs. standard therapy for older adults with CNS lymphoma
This study compares a high-dose chemotherapy followed by your own stem cell transplant to standard chemo-immunotherapy for older adults with newly diagnosed primary CNS lymphoma. The goal is to see which approach works better and is safer for people over 70.
Freiburg im Breisgau, Baden-WurttembergAges 65 years+ - NCT06478303Recruiting
Brain circuits for language and movement learning
This study uses brain imaging and stimulation to see how the brain connects language and movement. It may help improve how we learn motor skills and understand language.
Grenoble, GrenobAges 18–40 - NCT06478485Recruiting
A new way to plan neck surgery using MRI measurements
This trial is testing a new method to plan cervical spine surgery called laminoplasty. The goal is to use special measurements from MRI scans to better decide how to operate. This could lead to better recovery for people with spinal cord compression in the neck.
Nantong, JiangsuAges 18 years+ - NCT07042152Recruiting
Wearable device and coaching to improve arm use after stroke
This study tests whether a wearable device that tracks arm movement, plus coaching to use your weaker arm more, can help you recover better after a stroke. It's for people who are at least 6 months past their stroke and have some arm weakness but can still use their hand.
Irvine, CaliforniaAges 18–84 - NCT07495241Recruiting
How common is a carotid web in young people?
This study checks how often a small flap of tissue (called a carotid web) appears in the neck arteries of young people. It uses a simple ultrasound to look for this condition, which may help doctors understand stroke risk in younger adults.
Ostrava, Moravian-Silesian RegionAges 15–25 - NCT06461767Recruiting
rTMS for chronic migraine without recent prevention
This study tests whether repetitive transcranial magnetic stimulation (rTMS) — a noninvasive treatment using magnetic pulses on the head — can help prevent and treat chronic migraine pain. It may be an option for people who have never tried or are currently off migraine prevention medicines.
SohagAges Any age - NCT07493902Recruiting
Acupuncture for swallowing problems after a stroke
This study tests whether acupuncture can help people who have trouble swallowing after a stroke. It looks for volunteers who had a stroke within the past year and now have swallowing difficulty that is not too mild or too severe.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT05331664RecruitingPhase 4
Dropless vitrectomy eye drops for retinal detachment surgery
This trial studies a “dropless” method (fewer post-surgery eye drops) after pars plana vitrectomy, a surgery used to repair a retinal detachment. It may help by improving comfort and simplifying recovery for people having this specific type of retinal detachment repair.
Boston, MassachusettsAges 40 years+ - NCT06598644Recruiting
Comparing two gentle neck pain treatments
This study tests two hands-on treatments for long-lasting neck pain: a gentle gliding movement called Sustained Natural Apophyseal Glide (SNAG) and a soft-tissue release technique called Instrument Assisted Soft Tissue Mobilization (IASTM). If you have had neck pain for more than 3 months, this trial may help find which method works better for you.
Rawalpindi, Punjab ProvinceAges 20–45 - NCT05416905Recruiting
Deep brain stimulation for facial dystonia using GPi or STN
This trial studies deep brain stimulation (a surgically placed device that sends targeted electrical signals) to treat idiopathic craniofacial dystonia when medicines or botulinum toxin haven’t helped enough. It compares stimulating two brain targets (GPi versus STN) to see which approach may improve symptoms.
BeijingAges 18–75 - NCT06484088RecruitingEarly Phase 1
Brain scanning study of frustration in healthy adults
This study looks at how the brain handles frustration in healthy adults using a special brain scanner called magnetoencephalography (MEG). It may help researchers understand normal brain responses to frustration.
Bethesda, MarylandAges 18–55 - NCT07486037Recruiting
Exercise program for African American Alzheimer's caregivers
This study is for African American caregivers of someone with Alzheimer's or a related dementia. It explores whether a gentle exercise program can help you feel better and manage the stress of caregiving.
Indianapolis, IndianaAges 18–99 - NCT07482930Recruiting
Nerve stimulation and breathing test study in healthy adults
This study tests if a gentle nerve stimulation device placed on the ear can change how you breathe during a lung function test. It is only for healthy volunteers aged 18–40 who have no heart, lung, nerve, or mental health conditions.
SinopAges 18–40 - NCT07481669RecruitingPhase 2
Stem cell transplant for lymphoma at high risk of brain relapse
This trial tests a stem cell transplant with a special chemo combination (TEAM) to see if it can prevent lymphoma from coming back in the brain or spinal cord for people with high-risk non-Hodgkin lymphoma.
Hangzhou, ZhejiangAges 18–70 - NCT06017622Recruiting
THC Levels in Young People with Cannabis Overdose in the ER
This study looks at the amount of THC (the active ingredient in cannabis) in the blood of children and teens who come to the emergency room with severe drowsiness or confusion after using cannabis. It will help doctors better understand how cannabis affects young people.
Worcester, MassachusettsAges Any age - NCT06245434Recruiting
Circadian rhythms during coma awakening
This study looks at how the body's internal clock (circadian rhythm) changes as people wake up from a coma. Researchers hope to learn more about recovery patterns to improve care for patients with brain injuries.
Bron, LyonAges 17 years+ - NCT07478822RecruitingPhase 3
Botulinum toxin study for arm spasticity after stroke
This study tests a new botulinum toxin injection (YY001) for adults whose arm muscles are tight or stiff after a stroke. It looks at whether repeated treatments help with daily activities like washing and dressing.
BeijingAges 18–75 - NCT07515144Enrolling by invitation
Nerve Stretching for Muscle Strength in Older Adults
This study tests whether a gentle nerve-stretching technique in the leg can help older adults with age-related muscle loss regain strength and muscle size. You'll attend sessions where a therapist guides your leg through specific movements designed to mobilize nerves and improve muscle function.
Seremban, Negeri SembilanAges 60 years+ - NCT07127861Recruiting
Walking training on a treadmill after stroke
This study tests whether treadmill walking can improve how well people walk after a stroke. It may help those who already have some walking ability but want to get better.
Salamanca, SalamancaAges 18–80 - NCT07472491RecruitingPhase 2/Phase 3
Contrast MRI study for brain, spine, and body cancers
This trial tests a new contrast agent called mangaciclanol for MRI scans of the central nervous system (brain and spine) or body areas like the chest, belly, pelvis, and muscles. You may join if you have known or suspected tumors that need an MRI with contrast, and you're healthy enough to have two contrast MRIs within a short time.
Rochester, MinnesotaAges 18 years+ - NCT07128602Recruiting
Brain stimulation to help quadriceps after ACL surgery
This study tests whether a gentle, non-invasive brain stimulation can improve thigh muscle function in women recovering from ACL reconstruction. If you are between 2 and 6 months post-surgery, you may be able to join.
Glenside, PennsylvaniaAges 18–35 - NCT06463262Recruiting
Personalized markers for chordoma before surgery and radiation
This trial tests whether analyzing blood and tumor samples before and after radiation and surgery can help find personalized markers for chordoma. It is for patients with chordoma of the skull base, spine, or sacrum who will receive radiation before surgery.
Baltimore, MarylandAges 18 years+ - NCT07033468Recruiting
Virtual reality cognitive training for mild to moderate dementia
This study tests whether using a full-immersive virtual reality program can help improve thinking and memory skills in people with mild or moderate dementia. It aims to see if this type of training is both possible and helpful.
New Taipei CityAges 55 years+ - NCT07518927Enrolling by invitation
Brain Mapping Study Using Ultrasound and Implanted Electrodes
This research study uses focused ultrasound waves combined with brain electrodes (already implanted for your epilepsy or psychiatric treatment) to map how your brain responds. The goal is to better understand brain function and potentially improve future treatments.
Philadelphia, PennsylvaniaAges 21–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.