Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT07527104Recruiting
Bone marrow cells and rehabilitation for cerebral palsy in young children
This trial tests whether transplanting cells from a child's own bone marrow, combined with rehabilitation therapy, can improve movement and function in young children with cerebral palsy caused by birth-related brain injury or bleeding. The goal is to see if this approach helps children move better and become more independent.
Hanoi, HanoiAges 6 months–18 years - NCT06995638Recruiting
Multitasking training for older adults
This study tests whether a special online training program can help older adults improve their ability to multitask and stay focused. You'll do some computer exercises at home and come in for a few checkups, including a blood test.
Newark, New JerseyAges 60–75 - NCT07688538Recruiting
Mapping vision system development in embryos
This trial studies embryos to understand how the visual system develops normally and abnormally. It compares tissues from embryos with developmental problems to healthy ones, aiming to create a detailed map of early vision system growth.
Guangzhou, GuangdongAges Any age - NCT05699226Recruiting
Testing whether adjusting ECT treatment helps depression outcomes
This study tests a way of adjusting (titrating) ECT treatment to improve outcomes in people with major depression or bipolar II. It’s mainly for those who already need ECT with right-side electrode placement.
Albuquerque, New MexicoAges 50 years+ - NCT07686809Recruiting
Leg therapy for children with one-sided weakness
This study tests a new leg exercise program to help children with hemiplegia walk better. The therapy may improve balance and movement in the affected leg.
CairoAges 6–8 - NCT07683377Recruiting
Stent-assisted coil treatment for ruptured brain aneurysms
This trial tests if using a stent with coils to treat a ruptured brain aneurysm is safe and effective. It is for people who have a specific type of aneurysm (wide-necked, cystic) and are treated soon after the rupture.
Xi'an, ShaanxiAges 18–80 - NCT06701084Recruiting
Genetic Causes of Infant Epilepsy at Boston Children's
This study looks at the genetic causes of epilepsy that starts in babies under 1 year old. It aims to learn how a genetic diagnosis might help guide care.
Boston, MassachusettsAges Any age - NCT06982638Recruiting
Speeding up walking in Parkinson's with brain stimulation
This trial tests if a special type of brain stimulation (called TMS) can help people with Parkinson's disease who experience freezing of gait—when your feet feel stuck to the floor. The goal is to see if this treatment can improve walking and reduce those freezing episodes.
Charleston, South CarolinaAges 50–80 - NCT06767280Recruiting
Testing calf muscle in chronic nerve pain patients
This study looks at how a muscle in your calf (gastrocnemius) responds to a gentle electrical test in people with long-term nerve pain from the lower back. It aims to learn more about how the condition affects muscle function, which could help improve future treatments.
Sixth of October, Giza GovernorateAges 18–55 - NCT06973746Recruiting
Sitting up in a chair in the ICU for patients on breathing machines
This study tests whether getting patients who are on a breathing machine to sit in a chair helps them recover better. It looks at whether this simple activity can improve how well they get back to normal function.
Orléans, Centre-Val de LoireAges 18 years+ - NCT07673107RecruitingPhase 2
Botulinum toxin injection for essential tremor of hands and arms
This trial tests an investigational botulinum toxin injection (AGN-151607-DP) to reduce shaking in the hands and arms caused by essential tremor. It is for adults who have been diagnosed with this condition and who do not have certain nerve or muscle disorders.
Fresno, CaliforniaAges 18–85 - NCT06473285Recruiting
Esketamine for consciousness in prolonged disorders of consciousness
This trial tests whether a drug called esketamine can help improve brain activity in people with long-term disorders of consciousness. It may help doctors understand how the brain recovers.
BeijingAges 18–65 - NCT06056180Recruiting
Motor imagery training for balance in older adults
This study tests whether imagining moving your body (motor imagery training) can improve balance in older adults. It will compare this mental practice with usual activities to see if it helps prevent falls and improves stability.
Menteşe, MuğlaAges 60–80 - NCT07505914Recruiting
Breathing exercises for better thinking in older adults
This trial tests whether simple breathing exercises can improve memory and thinking skills in adults aged 65 and older. You would attend two sessions each week for 8 weeks.
IstanbulAges 65 years+ - NCT07660341RecruitingPhase 1
Study of CGB3002 in healthy volunteers
This trial tests a new drug, CGB3002, to see how safe it is and how the body processes it. Healthy volunteers are needed to help determine the right dose and check for side effects.
Melbourne, VictoriaAges 18–55 - NCT07498686Recruiting
Blood test for Parkinson's disease
This study is testing whether a simple blood test can help doctors better understand Parkinson's disease by looking at how a protein called alpha-synuclein behaves. It aims to find a new way to diagnose and track the disease.
Beijing, Beijing MunicipalityAges 18–95 - NCT06368726Enrolling by invitationPhase 1
Brain stimulation for kids with autism and genetic changes
This trial tests a gentle brain stimulation treatment called tDCS for children with autism or related conditions who also have certain genetic changes. It may help improve symptoms if your child meets the specific health and birth history requirements.
Albuquerque, New MexicoAges 6–11 - NCT07655869RecruitingEarly Phase 1
Lu177-DOTA-EB-RGD2 therapy for returning high-grade glioma
This trial tests a radioactive drug that targets a protein on tumor blood vessels to treat glioblastoma that has come back after standard treatment. It may help shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07224581RecruitingPhase 3
Study of a new drug for GRIN-related developmental disorder
This trial tests a new drug for children with GRIN-related neurodevelopmental disorder caused by certain gene changes. The drug aims to improve seizures and other symptoms.
Los Angeles, CaliforniaAges 1 month–18 years - NCT04107285Recruiting
Study brain changes in people with lymphoma after CAR T
This study looks at how thinking and brain function change over time in people with lymphoma who receive CAR T therapy. It may help doctors understand side effects and better support patients during and after treatment.
New York, New YorkAges 18 years+ - NCT05745298Recruiting
Electrical and breathing therapy to improve unassisted cough after spinal injury
This study tests whether pairing electrical stimulation with breathing muscle training can help you cough without needing assistance. It’s for people recovering from a spinal cord injury within the last year, and who can safely feel and respond to the electrical stimulation.
Miami, FloridaAges 18 years+ - NCT07523191Recruiting
Brain Activity Detection During Sleep Study
This research study tests a new method that uses magnetic pulses and brain-wave recordings to detect consciousness during sleep. Researchers want to validate this technology in healthy adults to see if it accurately measures brain activity.
Madison, WisconsinAges 18–85 - NCT06659120Recruiting
Fremanezumab to prevent period-related migraines
This study tests whether the migraine prevention drug fremanezumab can reduce the number of migraines you get around your period. It is for women who have regular cycles and migraines that are clearly linked to their menstrual period.
BernAges 18 years+ - NCT07438808Recruiting
How exercise affects brain flexibility in healthy adults
This study looks at how physical exercise might change the way the brain adapts and stays flexible in healthy younger and older adults. You may be able to join to help researchers understand how staying active keeps the brain sharp.
Loos, NordAges 20–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.