Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT07396454RecruitingPhase 2
Radiation plus anlotinib for HER2-negative breast cancer brain metastases
This trial tests whether adding anlotinib (a targeted therapy) to standard radiation can better control breast cancer that has spread to the brain. It is for people with HER2-negative breast cancer and at least one brain tumor seen on MRI.
NanjingAges 18–70 - NCT07110246RecruitingPhase 2
Dabrafenib and trametinib for BRAF-mutated low-grade gliomas
This trial tests two targeted drugs (dabrafenib and trametinib) for children and young adults with a specific type of low-grade brain tumor that has a BRAF V600 mutation. The drugs work by blocking signals that help the tumor grow.
Birmingham, AlabamaAges 1–25 - NCT06465251Recruiting
Home vs clinic arm therapy for stroke recovery
This study compares doing arm exercises at home versus in a clinic to help people who had a stroke 1-2 years ago improve their arm movement. It tests if home-based therapy works as well as clinic-based therapy.
Hong KongAges 50 years+ - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Anniston, AlabamaAges 18–80 - NCT07461584Recruiting
Memory boost in older adults with optimal dosing
This study tests a safe, non-invasive brain stimulation method to see if it can improve memory in healthy older adults. It uses carefully chosen doses to find the best approach.
Boston, MassachusettsAges 65 years+ - NCT07462546Recruiting
Ultrasound monitoring during carotid artery stenting
This trial is testing a special ultrasound (called transcranial Doppler) to monitor blood flow during a procedure to open a narrowed carotid artery in your neck. The ultrasound helps doctors see if the procedure is safe and working well.
ShenyangAges 40 years+ - NCT06310213Enrolling by invitation
Non-invasive pressure monitor for babies with hydrocephalus risk
This study tests a new, non-invasive way to monitor pressure in the brain for babies at risk of hydrocephalus. It uses a special contact lens and a small sticker, so no needles or surgery are needed.
Indianapolis, IndianaAges birth–1 year - NCT05964569RecruitingPhase 2
Personalized planning for proton radiation in low-grade brain tumors
This Phase 2 study tests a personalized, computer-guided way to plan proton beam radiation for adults with low-grade glioma. The goal is to see if the approach is feasible and can improve how treatment is planned.
HeidelbergAges 18 years+ - NCT07459244Recruiting
ECG changes in people who use methamphetamine
This study looks at the electrical activity of the heart (ECG) in people who use methamphetamine, including those who develop psychosis from it. It compares them to healthy volunteers to see if methamphetamine affects heart function.
Elâzığ, ElâzığAges 18–65 - NCT07700537Recruiting
Brain stimulation for speech recovery after recent stroke
This study tests a gentle brain stimulation treatment called tDCS to help people recover speech after a recent stroke. If you had a first-time stroke on the left side of your brain within the past 3 months and now have trouble speaking (aphasia), this treatment may help your brain relearn language.
Hefei, AnhuiAges 18–80 - NCT07457333Enrolling by invitationPhase 1/Phase 2
Beta-sitosterol for recovery after a brain aneurysm bleed
This study tests a natural compound called beta-sitosterol (from Gastrodia elata) to see if it can help people recover better after a brain aneurysm bleed. You must have had your aneurysm treated within 48 hours and be in relatively stable condition.
Hangzhou, ZhejiangAges 18–75 - NCT07441707RecruitingPhase 1
Tovorafenib for Japanese children and young adults with brain tumors
This study tests an experimental medicine called tovorafenib for children and young adults (6 months to 25 years) with Japanese ancestry whose low-grade brain tumors have returned or grown after prior treatment. The medicine targets tumors with a specific BRAF genetic change.
KanagawaAges 6 months–25 years - NCT07001267Recruiting
Comparing two anesthetics for stroke procedure recovery
This trial tests whether a sedative given through an IV or a gas you breathe affects recovery after surgery to remove a blood clot in the brain. It may help find the best way to keep you comfortable during the procedure to improve how well you do after three months.
Kansas City, KansasAges 18 years+ - NCT07456137Enrolling by invitation
Studying MRI vs. X-ray for spine pain
This trial compares two types of CT scans (upright vs. lying down) to see which gives better images of the lower back. It may help doctors choose the best scan for spine problems.
Kansas City, KansasAges 18 years+ - NCT06454955RecruitingEarly Phase 1
PET scan imaging study for solid tumors using a new probe
This trial tests a new imaging agent that targets a protein called B7-H3 found on many solid tumors. It uses PET/CT to help doctors see and stage tumors more clearly.
Beijing, Beijing MunicipalityAges 18–75 - NCT07423936Recruiting
Monitoring brain and organ activity in organ donors
This trial tests special monitors on organ donors after life support is withdrawn, to see how the organs and brain behave. It may help improve organ transplant outcomes.
Vancouver, British ColumbiaAges 19 years+ - NCT06450444Recruiting
Neuromodulation implant for chronic or frequent migraine
This trial tests a new implantable device that uses mild electrical pulses to prevent migraines. It is for people who have tried at least three migraine prevention medicines without success and still have frequent migraines.
Broadmeadow, New South WalesAges 18–84 - NCT07443397RecruitingPhase 3
Anlotinib plus whole-brain radiation for SCLC brain metastases
This trial tests whether combining Anlotinib (a targeted drug that blocks tumor blood vessel growth) with whole-brain radiation can better control brain metastases in small cell lung cancer patients. It is for people with up to 10 brain tumors who have not had brain radiation before.
Beijing, Beijing MunicipalityAges 18–80 - NCT07452081Recruiting
Sensory-motor therapy for postmenopausal nerve pain
This study tests a therapy that combines sensory and motor exercises to improve nerve function in women with postmenopausal polyneuropathy, a condition that causes numbness and tingling in the arms and legs. It aims to help those with type 2 diabetes who have had numbness for more than 4 months.
IsmailiaAges 45–55 - NCT07451431RecruitingPhase 4
Mirogabalin for diabetic nerve pain study
This study tests a new pain medicine called Mirogabalin for people with diabetic nerve pain that hasn't gotten better with usual treatments. It aims to see how well the drug works and if it is safe.
DhakaAges 40 years+ - NCT07389213Recruiting
Can brain stimulation and hearing aids slow memory loss in older adults with hearing loss?
This trial tests whether a non-invasive brain stimulation technique (rTMS) combined with hearing aids can help slow down thinking and memory decline in older adults who have age-related hearing loss.
Guangzhou, GuangdongAges 50–85 - NCT07407023Recruiting
Robotic hand therapy after recent stroke
This trial is testing a glove-like device to help people who had a recent stroke (2 days to 2 months ago) regain movement and feeling in their hand. It may be a good fit if your hand muscles are very weak and you can comfortably wear the device.
Milford, ConnecticutAges 18 years+ - NCT05492175Recruiting
Robotic therapy with games for arm recovery after stroke
This study compares two styles of robotic training (focused more on the shoulder/upper arm versus the hand/wrist) plus movement games to improve arm function after a first stroke. It may help people regain more useful arm and hand movement through guided, repeatable practice.
TaichungAges 20–80 - NCT07448857Recruiting
Scapula movement and muscle activity in upper string players with neck pain
This study looks at how the shoulder blade moves and muscles work in violin and viola players who have neck pain. It may help understand why neck pain happens and how to treat it better.
Taipei, TaiwanAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.