Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07724132RecruitingPhase 3
Treatments for sustained response in Alzheimer's disease
This study tests whether a treatment (atomoxetine or metformin) can help people with Alzheimer's disease maintain an improved state for at least 18 months. It may help you or a loved one stabilize symptoms and slow disease progression.
CambridgeAges 55 years+ - NCT07732374RecruitingPhase 2
Long-term results after hyperbaric oxygen therapy in veterans
This study follows veterans who previously finished a 40-session hyperbaric oxygen therapy (HBOT) program. It tracks how their memory, mood, and daily function are doing 12 weeks later, to understand long-term benefits.
Boise, IdahoAges 18 years+ - NCT07726875Enrolling by invitation
Orexin and confusion after surgery in older adults
This study looks at a brain chemical called orexin (which helps control wakefulness) in older adults after surgery. The goal is to see if orexin levels are linked to confusion or agitation that can happen when waking up from anesthesia. If you take part, your blood will be tested before and after surgery.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT07732244Recruiting
Testing a wireless brain oxygen monitor in the NICU
This study is testing a new wireless device that monitors oxygen levels in the brain. It is for babies already using a similar wired monitor, to see if the wireless version works just as well.
Montreal, QuebecAges Any age - NCT07729982Recruiting
Study tracking vision changes in OPA1 optic atrophy
This study follows people with a genetic form of optic atrophy over time to understand how vision changes. It does not test a treatment but helps doctors learn more about the condition to improve care.
Munich, BavariaAges Any age - NCT07731321Enrolling by invitation
Are Earplug Instructions Better One Way Or Another?
This study compares different ways of teaching people how to use earplugs. It will look at which method works best to protect hearing in a noisy workplace.
Chiang MaiAges 20–60 - NCT07731334Recruiting
Memory problems in non-neurology rehab patients
This study looks at how common mild cognitive impairment and dementia are in people staying in rehabilitation units for heart, lung, or orthopedic problems. It aims to understand memory and thinking issues that may be overlooked in these settings.
Florence, FIAges 45 years+ - NCT07725003Recruiting
Home-based rehab program vs. standard physical therapy for stroke recovery
This study compares a home-based motor relearning program with standard physical therapy delivered through video calls, to see which helps stroke survivors improve movement and function better. It may be a good option if you had a stroke 3 to 12 months ago and have access to a device with internet.
Faisalabad, Punjab ProvinceAges 40–70 - NCT07725601Recruiting
VNS dosing algorithm for epilepsy
This trial tests a new way to adjust the settings on a Vagus Nerve Stimulator (VNS) to better control seizures in people with epilepsy. It is for those who are already getting a VNS implanted to treat their seizures.
Augusta, GeorgiaAges 18–75 - NCT07730073Recruiting
LSVT-LOUD therapy for voice and speech in Parkinson's disease
This study tests whether LSVT-LOUD, a speech therapy program, can improve voice, speech, and quality of life in people with Parkinson's disease who have voice or speech problems. Participants must be native Turkish speakers, aged 40-80, with mild to moderate Parkinson's.
Kâğıthane, IstanbulAges 40–80 - NCT07724938Recruiting
Combination tonsil removal and nerve implant for sleep apnea
This study tests if removing the tonsils together with implanting a nerve stimulator (Hypoglossal Nerve Stimulation) can better treat sleep apnea in people whose throat sides collapse during sleep.
Boston, MassachusettsAges 18 years+ - NCT07728032Recruiting
How diet and medicine affect gut health in PKU children
This study looks at how a phenylalanine-restricted diet or certain PKU medicines affect gut health in children with PKU. It also includes healthy siblings or household members as a comparison group.
Birmingham, BirminghamAges 3–17 - NCT07724171Recruiting
Long-term results after PFO closure surgery
This study looks at how well patients do over time after having a hole in their heart (patent foramen ovale, or PFO) closed with a small device inserted through a vein. It may help doctors understand the benefits and risks of the procedure.
SeoulAges 19 years+ - NCT07726823Recruiting
Two types of manual therapy for leg pain from a bulging disc
This study compares two gentle, hands-on physical therapy techniques to see which better relieves leg pain from a bulging lower back disc. Participants will receive one of the two treatments over several sessions.
Lahore, Punjab ProvinceAges 20–40 - NCT07726758Recruiting
Squat exercise for pre-sarcopenia in older adults
This study tests if doing squat exercises can help improve muscle strength and function in older adults with early muscle loss (pre-sarcopenia). It is for people 65 and older living in Hualien.
TaipeiAges 65–100 - NCT07726017Recruiting
Balance and walking exercises for chronic stroke recovery
This study compares two types of walking and balance exercises for people who had a stroke 6 to 12 months ago. It aims to see which type of practice helps improve balance and walking best.
SialkotAges 40–70 - NCT07731087Recruiting
Stem cell secretion therapy for thinking recovery after stroke
This study tests whether a therapy made from stem cell secretions can help improve memory and thinking after an ischemic stroke. It is for people who had a clot-related stroke in the past 3 months and now have mild to moderate cognitive issues.
Makassar, South SulawesiAges 40–75 - NCT07727239Recruiting
Brain stimulation trial for people with narcolepsy type 1
This trial tests a non-invasive brain stimulation method called temporal interference to target the hypothalamus. It aims to help reduce excessive daytime sleepiness in people with narcolepsy type 1.
Xi'an, ShaanxiAges 12–60 - NCT07725471Recruiting
Comparing breathing and neck release in stroke recovery
This study compares two gentle therapy techniques—special breathing exercises and a hands-on release at the base of the skull—to see which helps stroke survivors with one-sided weakness regain movement and breathing. It may be a good fit if you're still recovering from a first stroke months ago and don't have major heart or lung problems.
AfyonkarahisarAges 18–84 - NCT07729735Enrolling by invitation
Physiotherapy after breast reduction surgery
This study tests whether adding physical therapy after breast reduction surgery helps you recover faster and feel better. You must be between 18 and 50, have had cosmetic breast reduction, and be free of certain health conditions like arm swelling or nerve problems.
IstanbulAges 18–50 - NCT07730957Recruiting
Music program to reduce care refusal in nursing home residents
This trial tests whether a structured music program can help reduce care refusal (like agitation or aggression during bathing) in nursing home residents with memory or thinking problems. Residents who show these behaviors may be eligible.
AmiensAges 18 years+ - NCT07726082Recruiting
A group program to help with long-term fatigue
This study tests a new way to help people with long-term fatigue that gets in the way of daily life. It uses a group program that focuses on making small, helpful choices to feel better.
BaselAges 18–65 - NCT07724730Recruiting
Moving with and without music after a stroke
This study compares two types of movement practice for people recovering from a recent stroke. One group will do everyday tasks like walking and reaching, and the other will do the same movements but with a rhythmic beat to help with timing and coordination.
Daska KalanAges 40–60 - NCT07730086Recruiting
Using smartphones to study walking in children with cerebral palsy
This trial uses a smartphone app to measure how children with cerebral palsy walk. It aims to see if phone sensors can help doctors better understand gait problems.
Minya, Menia GovernorateAges 6–12
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.