Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06774508Recruiting
Exercise plus brain training for older adults at risk of falling
This study tests a program that combines high-intensity exercise with mental challenges to improve balance and mobility. It is designed for older adults who feel unsteady or have fallen recently.
UmeåAges 75 years+ - NCT07220252RecruitingPhase 2/Phase 3
Ublituximab for children with relapsing multiple sclerosis
This trial tests a new drug called ublituximab to see if it can reduce flare-ups in children and teens who have relapsing multiple sclerosis. It aims to understand if the treatment is safe and effective for younger patients.
GdanskAges 10–17 - NCT07447557RecruitingPhase 1/Phase 2
Gene therapy study for Charcot-Marie-Tooth type 4J (CMT4J)
This trial tests a gene therapy medicine (ELP-02) given through a spinal tap for children and young adults with a specific genetic form of CMT (CMT4J). It aims to slow or stop the disease from getting worse.
Palo Alto, CaliforniaAges 3–20 - NCT07448350Recruiting
TENS therapy for better sensation after leg amputation
This study tests if a gentle electrical stimulation method called TENS can help people who have lost a leg below or above the knee feel more natural sensations in their missing limb and reduce phantom limb pain.
Rome, RomeAges 18–80 - NCT07435610Recruiting
Acupuncture for children with stomach pain and related issues
This study tests whether acupuncture can help children with stomach pain or other gut-brain interaction disorders. It may be a good option if your child's current treatments aren't working well enough.
Irvine, CaliforniaAges 8–17 - NCT07446530Enrolling by invitation
Gamified movement for kids with sensory integration issues
This study looks at whether fun, game-based exercises can help children with sensory integration issues (like trouble with balance, body awareness, or touch sensitivity). If your child qualifies, they will take part in a gamified movement program designed to improve these skills.
Changchun, JilinAges 3–6 - NCT07614126Recruiting
L-dopa Treatment for Children With CTNNB1 Gene Disorder
This study tests whether L-dopa medication can help children with a rare genetic disorder (caused by changes in the CTNNB1 gene) that causes involuntary muscle movements called dystonia. Researchers want to see if this medicine can reduce these movements and improve daily function.
Montpellier, HéraultAges 1–15 - NCT07443072Recruiting
Heart rate and brain waves to predict recovery after brain surgery
This study monitors your heart rate and brain waves during and after brain surgery to see if they can help doctors predict how well you will recover. It aims to improve care for future patients.
MilanAges 18 years+ - NCT05209620RecruitingPhase 2
Orelabrutinib plus pemetrexed for lymphoma in the brain
This Phase 2 trial tests a combination medicine (orelabrutinib with pemetrexed) to treat lymphoma that has returned or is not responding, specifically in the brain or spinal fluid. If you qualify, the goal is to shrink measurable tumors and improve control of central nervous system lymphoma.
Zhengzhou, HenanAges 18–75 - NCT07444034Recruiting
Study of a Portable Head MRI Scanner
This trial is testing a new, portable MRI machine that only scans your head. It may be easier and more comfortable than a standard MRI.
Minneapolis, MinnesotaAges 18 years+ - NCT07402928Recruiting
Dopamine signals in health and Parkinson's
This study uses MRI scans to look at dopamine signals in the brain. The goal is to understand how Parkinson's affects these signals.
HvidovreAges 35 years+ - NCT06965478Recruiting
Vision and drug effects study for adults 18–60
This trial tests how vision works under different conditions. You may be eligible if you are between 18 and 60, have normal or corrected vision, and do not have certain eye conditions, sleep issues, or implants.
Providence, Rhode IslandAges 18–60 - NCT07427836Recruiting
Better diagnosis and surgery choice for normal pressure hydrocephalus
This study uses a combination of tests (like brain scans, walking tests, and memory checks) to more accurately diagnose a brain fluid condition called 'normal pressure hydrocephalus' and to decide if surgery might help. The goal is to improve treatment choices for people with this condition.
MilanAges 60–85 - NCT06889896Enrolling by invitation
Blood test for Alzheimer's brain changes
This study uses a simple blood test to quickly detect Alzheimer's-related brain changes (amyloid plaques). It may help people with memory concerns avoid a more invasive PET scan and get answers faster.
Hefei, AnhuiAges 45–85 - NCT06951035Recruiting
Brain stimulation and BCI for arm movement after stroke
This study tests whether combining brain stimulation (rTMS) with a brain-computer interface (a device that reads your brain signals) can help improve arm and hand movement after a stroke. It is for people who had a single stroke more than 6 months ago and still have some weakness but can move their fingers slightly.
ParisAges 18–85 - NCT06587113Recruiting
Study of attention and focus during visual search
This study explores how your brain focuses and ignores distractions while searching for things visually. It may help us understand attention processes in healthy adults.
Denver, ColoradoAges 18–65 - NCT05828628Recruiting
Study tests imaging and tissue markers in brain lymphoma
This study looks at how primary central nervous system (CNS) lymphoma can be identified and tracked using scans and molecular (tissue/biomarker) tests. It may help doctors better understand your disease and choose the best next steps.
SuttonAges 18 years+ - NCT07420803Recruiting
Nerve stimulation study for chronic dizziness
This study tests if a gentle, non-invasive nerve stimulation in the ear can help reduce chronic dizziness. It is for people with a specific type of dizziness called PPPD that has lasted at least 3 months.
Jacksonville, FloridaAges 18 years+ - NCT05887934Enrolling by invitation
Bone lead levels and mental health in adults
This study looks at whether the amount of lead stored in the body (from old exposures) is linked to brain activity and mental health. It may help researchers understand what kinds of brain/mental health symptoms are related to lead exposure.
Charleston, South CarolinaAges 18–70 - NCT07415707Recruiting
Reducing alcohol and taking probiotics for brain health in older adults
This study tests whether cutting back on alcohol and taking probiotics can improve memory and thinking in older adults who are heavy drinkers. If you are interested in drinking less, you may be able to join.
Miami, FloridaAges 65–84 - NCT07413731Recruiting
Medication tapering with spinal cord stimulation
This trial tests how changing your pain medications while using a spinal cord stimulator affects your nervous system. It may help people with chronic lower back pain find the best way to manage their pain and reduce reliance on strong drugs.
WilrijkAges 18 years+ - NCT07413718Recruiting
Breathing muscle training for ALS patients
This study tests whether a special breathing muscle training can help people with ALS maintain lung function. It may benefit patients diagnosed recently with spinal ALS and good breathing capacity.
Donostia / San Sebastian, GipuzkaAges 18–85 - NCT06581887Recruiting
Measuring behavior and emotions in Duchenne and Becker muscular dystrophy
This study looks at how to measure behavioral and emotional challenges in boys with Duchenne or Becker muscular dystrophy, and in boys without the condition. It aims to find better ways to assess these issues, which could help improve care and treatments.
LondonAges 7–17 - NCT07410702Recruiting
Brain activity during anesthesia for planned surgery
This study looks at how anesthesia changes brain activity using EEG (a non-invasive brain wave recording). Researchers want to see if these changes relate to how conscious you are during surgery. This could help doctors provide safer anesthesia care.
Wuhan, HubeiAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.