Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07730879Recruiting
Wall Squat Exercise for Blood Pressure in Sleep Apnea
This study tests whether a simple wall squat exercise can help lower blood pressure in people who have both high blood pressure and sleep apnea (treated with CPAP). If you are using CPAP regularly and are otherwise healthy enough to exercise, this trial may be a good fit for you.
BragaAges 18–80 - NCT07726823Recruiting
Two types of manual therapy for leg pain from a bulging disc
This study compares two gentle, hands-on physical therapy techniques to see which better relieves leg pain from a bulging lower back disc. Participants will receive one of the two treatments over several sessions.
Lahore, Punjab ProvinceAges 20–40 - NCT07726550Recruiting
Comparing two nerve blocks for open kidney surgery pain relief
This study compares two different nerve-block techniques to see which works better for pain control after open kidney surgery. One block targets muscles between the ribs, the other targets muscles around the spine. You will be randomly assigned to one of the two groups.
Tekirdağ, TekirdağAges 18–65 - NCT07726563Recruiting
Plasmapheresis for ALS with NRIP2 antibody
This trial tests whether a blood filtering treatment called plasmapheresis can help people with ALS who have a specific antibody (NRIP2) in their blood. It aims to see if removing this antibody can slow the disease and improve symptoms.
Taipei City, TaipeiAges 20 years+ - NCT07730957Recruiting
Music program to reduce care refusal in nursing home residents
This trial tests whether a structured music program can help reduce care refusal (like agitation or aggression during bathing) in nursing home residents with memory or thinking problems. Residents who show these behaviors may be eligible.
AmiensAges 18 years+ - NCT07726043Recruiting
Rehab with vibration therapy for balance in CMT1A
This trial tests whether adding a special vibration device to an intensive rehab program helps improve balance in people with Charcot-Marie-Tooth disease type 1A. If you are between 18 and 65 and have mild to moderate leg weakness, you may be able to join.
MarseilleAges 18–65 - NCT07724132RecruitingPhase 3
Treatments for sustained response in Alzheimer's disease
This study tests whether a treatment (atomoxetine or metformin) can help people with Alzheimer's disease maintain an improved state for at least 18 months. It may help you or a loved one stabilize symptoms and slow disease progression.
CambridgeAges 55 years+ - NCT07728734Enrolling by invitation
Predicting recovery after a brain bleed
This study is testing a way to predict how well people will recover after a brain bleed (intracerebral hemorrhage). It uses information from the first 24 hours to help doctors and families understand the chances of getting better.
Badalona, BarcelonaAges 18 years+ - NCT04635436Recruiting
Split-walking training for one-sided leg weakness when walking hurts
This trial tests whether a “split gait” walking training method can improve walking balance and how you move when you have one-sided leg problems and pain or limitations when walking. It may help reduce walking difficulties by training your stepping pattern safely.
Milan, MIAges 18–70 - NCT06118736Recruiting
Guided bone growth to prevent hip problems in children with cerebral palsy
This trial tests a surgery to guide the growth of the upper thigh bone (femur) to keep the hip joint from sliding out of place in children with spastic cerebral palsy. It aims to prevent further hip migration and avoid more serious hip problems later.
AmsterdamAges 2–8 - NCT06221332Recruiting
Sacral block for pain control during normal birth
This trial studies a new pain-block method called the sacral erector spinae plane block, given along with your epidural during labor. It is for first-time mothers having a planned vaginal birth, and aims to see if it gives better pain relief.
KonyaAges 18–42 - NCT06600269Recruiting
Cycling training for ataxia recovery in SCA
This study tests whether cycling-based coordination training can help people with spinocerebellar ataxia (SCA) improve balance and movement by priming the brain for recovery.
TaoyuanAges 18 years+ - NCT06598878Recruiting
AR-assisted walking training for Parkinson's
This trial tests walking training with augmented reality (AR) goggles to help with movement in Parkinson's disease. It may help improve your gait and balance.
TaoyuanAges 20 years+ - NCT06629116Recruiting
Albumin treatment for large strokes after thrombectomy
This trial tests if giving a protein called albumin after a large stroke can improve recovery. Albumin may help reduce brain swelling and damage. You may qualify if you had a large stroke in the front part of the brain, got a clot-removal procedure, and meet certain age and health criteria.
Zhangzhou, FujianAges 18–80 - NCT06631742Recruiting
Exergaming for dementia: a fun exercise trial
This trial tests whether playing interactive video games that combine exercise and thinking challenges (called 'exergaming') can help people with dementia. It aims to see if this fun way to move and think can improve memory, daily function, and quality of life.
Wetzikon, Canton of ZurichAges Any age - NCT06630949Recruiting
Vitamin D3 and creatine for muscle health in older adults
This study tests whether taking a combination of vitamin D3 and creatine can help older adults with mild mobility problems maintain or improve their muscle function. If you have minor trouble with walking, stairs, or getting in/out of a car, this trial may offer a simple way to help keep your muscles strong.
Hamilton, OntarioAges 60 years+ - NCT05603533Recruiting
Music group sessions to help people with dementia exercise
This trial studies whether guided group exercise with music can improve how well people with moderate dementia follow exercise plans. Participants will join a nursing-home based music and movement group program.
Kasterlee, AntwerpenAges 65 years+ - NCT05822258Recruiting
Tracking freezing while walking in Parkinson’s using motion sensors
This study tests motion-sensor devices (small inertial measurement units) to detect moments when walking suddenly “freezes” in Parkinson’s disease. If you have freezing episodes, it may help researchers measure them more accurately and support better monitoring.
Rennes, Brittany RegionAges 18 years+ - NCT06509503RecruitingPhase 4
Effect of birth control pills on migraine
This study tests how combined oral contraceptive pills affect migraine in women. It will compare people who take these pills with those using non-hormonal methods like an IUD, to see if the pills help or change the migraine pattern.
Kafr ash ShaykhAges 18–55 - NCT06627491Recruiting
How imagined muscle contractions affect your muscles and brain
This study looks at how imagining different types of muscle contractions (fast vs. slow) might change your muscle function and how your brain controls them. It could help us understand new ways to improve strength without actual exercise.
Kennesaw, GeorgiaAges 18–30 - NCT06634264Recruiting
Comparing two therapies for children with sleep apnea after surgery
This study compares two different exercises (called oral reeducation) to see which works better for children who still have breathing problems during sleep even after getting their tonsils or adenoids removed. It helps kids breathe easier at night.
Montreal, QuebecAges 4–14 - NCT05295498Recruiting
Brain stimulation trial for nerve pain relief
This trial studies whether repeated magnetic stimulation of the brain can reduce ongoing nerve pain. It may help people whose nerve pain has been steady for at least a month and who still need pain medicine more than once a week.
KrakowAges 18 years+ - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT07723313RecruitingEarly Phase 1
Amniotic membrane and secretome for carpal tunnel release
This trial tests whether adding a special membrane (amniotic membrane) and a natural healing fluid (secretome) to standard carpal tunnel release surgery can improve hand function better than surgery alone. It may be a good option if your wrist pain and numbness haven't gone away with other treatments.
Denpasar, BaliAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.