Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT07409220Recruiting
Using video to help parents prepare for child's lumbar puncture
This study tests if showing parents a short video before their child's lumbar puncture helps them feel calmer and more informed. The goal is to make the experience less stressful for both parents and children.
Muscat, Muḩāfaz̧at MasqaţAges 12 hours–13 years - NCT07409506Recruiting
How caregivers help people with Alzheimer's
This study looks at the support that caregivers provide to people with Alzheimer's disease at different stages. It helps researchers understand how caregiving changes over time, which can lead to better support for both patients and their families.
VilleurbanneAges 60 years+ - NCT06924996Enrolling by invitation
Thrombectomy for large stroke in back of the brain
This trial is testing whether a clot removal procedure, called endovascular thrombectomy, can help people who have a large stroke in the back part of the brain. To be eligible, the stroke must be from a blocked artery in the base of the skull, and the stroke must be severe and recent.
Beijing, Beijing MunicipalityAges 18–80 - NCT04054414RecruitingPhase 2
Drug study for improving recovery after acute spinal cord injury
This Phase 2 trial tests sotateltide (PMZ-1620) in people with a recent spinal cord injury. It aims to see whether the drug can improve neurological recovery after injury, especially in certain levels and types of incomplete injuries.
BelagaviAges 18–75 - NCT07454473RecruitingPhase 4
Edaravone and Dexborneol for chemo-related memory loss
This trial tests if a sublingual tablet can help people who have memory and thinking problems related to chemotherapy. If you have had certain types of chemotherapy and now notice trouble with your memory or concentration, this treatment might help improve your symptoms.
Shenyang, LiaoningAges 35–80 - NCT05927428RecruitingPhase 2
Eye drops for neurotrophic corneal ulcers
This Phase 2 trial tests BRM424 eye drops in adults with neurotrophic keratitis (a weakened, slow-healing cornea) to see if they help and are safe over 28 days. You may be able to join if your condition matches Stage 2 or Stage 3 and you meet the safety rules.
Leland, North CarolinaAges 18 years+ - NCT07398352Recruiting
Regional anesthesia effects on brain oxygen in shoulder surgery
This trial studies how regional anesthesia affects oxygen levels in the brain and a key artery during shoulder surgery. It aims to find which anesthesia method works best for oxygen supply.
SanliurfaAges 18–65 - NCT07397897Enrolling by invitation
Brain stimulation and memory test study
This trial uses brain stimulation (TMS) to see if it can improve memory. It involves recording brain activity with electrodes already placed for medical reasons.
Chicago, IllinoisAges 18 years+ - NCT07150260Recruiting
Brain oxygen and artery pressure study during awake carotid surgery
This study looks at how blood pressure in the carotid artery relates to oxygen levels in the brain during awake carotid surgery. It may help doctors better understand how to protect your brain during the procedure.
IzmirAges 18 years+ - NCT03972124RecruitingPhase 2
Cannabis to prevent migraine attacks before they start
This Phase 2 trial tests whether using cannabis can prevent migraine attacks from happening. It specifically looks at people with chronic migraine who have tried and not benefited from other prevention medicines.
Calgary, AlbertaAges 25 years+ - NCT07393074Recruiting
Liver cancer and nervous system study
This study looks at how the nervous system works in people with liver cancer (hepatocellular carcinoma) or liver scarring (cirrhosis) who need a liver biopsy. It aims to see if there is a link between the nervous system and liver tumors.
LyonAges 18 years+ - NCT07390136Recruiting
Brain development study for babies with and without early brain injury
This study looks at how babies' brains develop, comparing infants who had a brain injury around birth with healthy babies. It could help understand early thinking and learning abilities.
Madison, WisconsinAges 3 months–2 years - NCT04209153Recruiting
Brain stimulation study to help people quit nicotine addiction
This trial tests whether direct brain electrical stimulation can help people who use tobacco every day. You must have strong nicotine dependence and be able to follow the study in French, while avoiding certain health and safety conditions.
Paris, IDFAges 18 years+ - NCT07388576Recruiting
AP-Brain supplement for attention in healthy young adults
This trial tests a supplement called AP-Brain to see if it helps with attention and focus in healthy young adults (ages 18–39) who feel they have attention problems. It compares different doses to find the safest and most effective one.
London, OntarioAges 18–39 - NCT06912724Recruiting
Pediatric Neuroimaging Study for Healthy Kids
This study uses MRI scans to look at the brains of healthy children ages 9 to 14. It helps researchers learn about normal brain development.
Baltimore, MarylandAges 9–14 - NCT07386236Recruiting
Brain signals during smell testing in epilepsy surgery patients
This study measures brain activity while you smell different odors. It may help doctors understand how the brain processes smells in people undergoing epilepsy surgery.
Chicago, IllinoisAges 12–65 - NCT06414278Recruiting
Spotting early thinking and memory changes with immunotherapy
This study looks at how a special type of immunotherapy called CAR-T therapy might affect your thinking skills, memory, and ability to focus. By checking on patients early and often, the team hopes to find simple ways to detect and manage these side effects sooner.
Minneapolis, MinnesotaAges 18 years+ - NCT07318714RecruitingPhase 1/Phase 2
Study of ASP2246 for movement problems after a stroke
This study tests an experimental treatment called ASP2246 for people who have movement problems after a stroke. It aims to see if it can help improve arm and leg function when combined with rehabilitation therapy.
Sendai, MiyagiAges 18–80 - NCT07379723Recruiting
Brief therapy for Functional Cognitive Disorder: a feasibility study
This study tests a brief psychological therapy for people with Functional Cognitive Disorder (difficulties with memory or thinking that aren't linked to a brain disease). The goal is to see if this approach can help manage symptoms and if it is possible to run a larger trial.
LondonAges 18–65 - NCT06994507RecruitingPhase 3
GM1 to prevent nerve damage from breast cancer chemo
This trial tests whether a drug called GM1 can prevent nerve damage (numbness, tingling, or pain in hands/feet) caused by a common chemotherapy drug used for breast cancer. If you are starting chemotherapy with nab-paclitaxel, this study may help protect your nerves.
BeijingAges 18–75 - NCT06950242Enrolling by invitation
Laser balloon for narrowed brain arteries
This trial tests a new laser balloon catheter to widen narrowed arteries in the brain that cause stroke symptoms. It may help if you have a severely blocked artery and are healthy enough for the procedure.
Changzhou, JiangsuAges 18–80 - NCT05648812RecruitingPhase 3
Ultrasound tests for baby brains using special imaging
This Phase 3 study tests whether detailed ultrasound scans (with contrast and stiffness measurements) can help doctors assess a baby’s brain. It may help by improving how early brain changes are detected in newborn care settings.
Turku, Southwestern FinlandAges 1 minute–6 months - NCT07417072Recruiting
Brain tumor drug testing using 3D models in children
This study creates 3D models from brain tumor tissue of children aged 3-18 to test how different drugs might work against their specific tumor. The goal is to find more personalized treatments.
Florence, FirenzeAges 3–18 - NCT07374913Recruiting
Study of COL4A1 and COL4A2 gene mutations
This study looks at people with a mutation in the COL4A1 or COL4A2 genes, which can cause problems in small blood vessels throughout the body. It aims to learn more about the condition and may also include family members who carry the mutation or who can serve as healthy controls.
Florence, FIAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.