Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT07372833Recruiting
CAMK2-related brain disorders natural history study
This study tracks the health and development of people with a specific genetic change in the CAMK2 genes. By joining, you help researchers understand the condition better, which may lead to better treatments in the future.
Rotterdam, South HollandAges Any age - NCT06158529Recruiting
High-frequency spinal cord stimulation for diabetic nerve pain
This trial tests if a special type of spinal cord stimulation (high-frequency SCS) can better relieve painful nerve damage caused by diabetes. If you have long-term burning, stabbing, or electric-shock-like pain in both legs, this treatment may help reduce that pain.
BeijingAges 18–80 - NCT07449676Recruiting
Tui Jing therapy for depression study
This study tests a gentle hands-on therapy based on Traditional Chinese Medicine, called Tui Jing, to see if it improves mood and brain function in people with depression. It lasts 12 weeks and compares the therapy with a placebo.
Hong Kong, Hung HomAges 18–55 - NCT07604688Recruiting
Registry Study of Dural Arteriovenous Fistulas in China
This study collects information from patients diagnosed with abnormal blood vessel connections in or around the brain or spine. Researchers will track your diagnosis, treatment, and outcomes to better understand these conditions and improve care.
BeijingAges 18 years+ - NCT07367477Enrolling by invitation
Horizontal vs. vertical arm exercises for children with cerebral palsy
This study compares two types of arm and hand exercises (horizontal vs. vertical movements) for children with bilateral spastic cerebral palsy. It aims to see which type helps improve upper body function the most.
CairoAges 5–8 - NCT07367880Recruiting
Testing a new tool for naming and identifying unique things
This study tests a new tool called the Monument Test, which checks how well people can name and recognize famous landmarks or unique items. It may help assess memory and thinking skills in adults with or without Alzheimer's disease.
GrenobleAges 50–95 - NCT06558578Recruiting
Helicobacter pylori infection and migraine in children
This study looks at whether a stomach infection (Helicobacter pylori) is linked to migraine headaches in children. If your child has migraines, this trial could help find a possible connection.
SohagAges 6–16 - NCT07299734RecruitingEarly Phase 1
Augmented reality + electrical stimulation for hand grasp
This trial tests a system that combines a video-like overlay (augmented reality) with small electrical pulses to help you grasp objects. It may improve your hand function and control.
Toronto, OntarioAges 18–65 - NCT06405971Recruiting
Metformin for unruptured brain aneurysms
This trial tests whether the diabetes drug metformin can help prevent unruptured aneurysms in the back part of the brain from growing or causing problems. It is for people whose aneurysms show a specific sign on an MRI scan.
Beijing, Beijing MunicipalityAges 18–75 - NCT04927338RecruitingPhase 2
Bacopa supplement study for Gulf War illness symptoms
This trial tests whether Bacopa (a herbal supplement) can improve symptoms of Gulf War Illness (GWI). You may be eligible if you served in the Gulf War and still have ongoing, hard-to-explain fatigue and related symptoms.
Davie, FloridaAges 46–78 - NCT07357389Recruiting
Preventing ICU confusion with virtual reality
This study tests whether using virtual reality (VR) in the ICU can help prevent confusion (delirium) in patients. If you are in the surgical ICU at Cedars-Sinai and are expected to stay more than 2 days, you might be able to participate.
Los Angeles, CaliforniaAges 18 years+ - NCT07356336Recruiting
Talking therapy for dementia behavior symptoms in nursing homes
This study tests a non-drug therapy that helps caregivers understand and respond to challenging behaviors in people with dementia. It is designed for nursing home residents who have symptoms like agitation, depression, or sleep problems.
Tienen, Vlaams-BrabantAges 60 years+ - NCT07402161Recruiting
Finding Alzheimer's earliest signature in memory concerns
This study looks for early signs of Alzheimer's in people who feel their memory is slipping but still function normally. You'll help researchers find a pattern—a 'signature'—in the brain that may signal the earliest stages of the disease.
San Donato Milanese, MilanAges 18 years+ - NCT06940791RecruitingPhase 2
Tirabrutinib vs placebo for CNS lymphoma in remission
This trial tests whether taking the drug tirabrutinib (a pill) can help keep primary CNS lymphoma from coming back after successful initial chemotherapy. It compares the drug to a placebo (a dummy pill).
TokyoAges 18 years+ - NCT06883747RecruitingEarly Phase 1
Study of BMS-986504 for recurrent brain tumor
This trial tests an experimental drug, BMS-986504, for people with recurrent glioblastoma (a type of brain cancer). The drug targets a specific genetic change in the tumor. It aims to see if the drug can help shrink or slow the tumor.
Phoenix, ArizonaAges 18 years+ - NCT07339319Recruiting
Treatment and recovery for mild head injury
This study looks at how people with mild head injuries are treated and recover. It may help doctors improve care for patients who have a mild head injury and get a brain scan.
BolognaAges 18 years+ - NCT05698810Recruiting
Study exams practice for upcoming research
This trial checks whether it’s practical and workable to set up study-related exams before planned research. It mainly recruits adults who can consent and be contacted, so the team can prepare future studies smoothly.
GrenobleAges 18 years+ - NCT06922396Recruiting
Mortality predictors for head trauma patients
This study looks at patients with a traumatic brain injury to find factors that predict death. It may help doctors better understand who is at highest risk.
CairoAges 16–75 - NCT06788808Recruiting
Ultrasound study of fetal brain development in pregnancy
This study uses ultrasound to examine fetal brain and spine development in pregnant women. It compares scans from pregnancies where a brain or spine issue is suspected with those from healthy pregnancies to improve understanding and diagnosis.
Bologna, BolognaAges 18–45 - NCT07571304Recruiting
Dual-Task Training for Teens with Multiple Sclerosis
This study tests whether doing two things at once while exercising (like walking while counting) helps teenagers with multiple sclerosis improve balance, coordination, and daily functioning. The goal is to see if this type of training is better than standard exercise for managing MS symptoms.
IstanbulAges 12–18 - NCT05546307Recruiting
Testing whether pre-relaxation improves arm nerve test recordings
This study looks at whether doing a relaxation session before an arm nerve test makes the results easier to record and interpret. If you’re having an arm nerve test, relaxation beforehand may help get clearer measurements.
Amiens, PicardieAges 18–70 - NCT06488807Recruiting
Smell therapy to prevent confusion after surgery
This study tests whether a simple smell-based activity before and after surgery can help prevent confusion and memory problems in older adults. It is for people 65 and older who are having a long surgery under general anesthesia.
ShanghaiAges 65 years+ - NCT07327710Enrolling by invitation
Brain-Computer Interface and Electrical Stimulation for Facial Paralysis
This trial tests a non-invasive treatment that combines a brain-computer interface with mild electrical stimulation to help people with one-sided facial paralysis regain movement. It aims to improve facial muscle function by retraining the brain and muscles together.
Changzhou, JiangsuAges 18–75 - NCT06539767Recruiting
Brain aneurysm risk study using MRI
This study looks at people with brain aneurysms to understand which ones are more likely to cause problems. It uses a special MRI to get detailed images and help predict risk.
Guangzhou, GuangdongAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.