Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06892340Recruiting
Testing a device to prevent motion sickness and disorientation
This study is testing a device that may help reduce motion sickness and feelings of disorientation. Healthy people who do not usually get motion sickness are needed to participate.
San Antonio, TexasAges 18–50 - NCT07195825RecruitingPhase 1
Gene therapy BBM-P002 for Parkinson's disease safety trial
This trial tests a new gene therapy called BBM-P002 for Parkinson's disease. It aims to see if the treatment is safe and tolerable, and may help people with moderate to advanced Parkinson's who have had the condition for at least 5 years.
Shanghai, Shanghai MunicipalityAges 40–70 - NCT07696598Recruiting
Brain bleed surgery study in children after head injury
This study looks at how children under 18 do after surgery for a specific type of brain bleed (called an extradural or epidural hematoma) caused by a head injury. The goal is to understand what helps them heal better.
Sohag, Sohag GovernorateAges 1 day–18 years - NCT07322315Recruiting
Ultrasound test for brain injuries in newborns
This study uses a special ultrasound (called transcranial Doppler) to check for brain injuries in high-risk newborns. It might help doctors find problems early in babies who are sick or had a difficult birth.
Kafr ash Shaykh, KafrelsheikhAges Up to 9 months - NCT06492213Recruiting
Combining PRP with Radiofrequency for Face Nerve Pain
This study tests whether adding platelet-rich plasma (a concentrate from your own blood that may help healing) to a standard pulsed radiofrequency procedure reduces pain from infraorbital neuralgia more effectively than radiofrequency alone. It involves two treatments and follow-up for several months.
Beijing, Beijing MunicipalityAges 18–75 - NCT07321587Recruiting
Walking, texts, and videos for older adults and their care partners
This study tests whether a program of Fitbit tracking, text reminders, exercise videos, and walking with a care partner can help older adults (with or without mild dementia) become more active. It is designed for people who are willing to use a smartwatch and stay connected via phone or internet.
New York, New YorkAges 18 years+ - NCT06491693Recruiting
Can eye nerve test predict brain complications after carotid surgery?
This trial checks if measuring the nerve sheath in your eye can help doctors predict brain-related problems after carotid artery surgery. It aims to improve safety during the procedure.
IstanbulAges 50–80 - NCT06978348Recruiting
AI model to predict stroke using ultrasound
This trial is building an AI tool to predict ischemic stroke risk based on carotid and vertebral artery ultrasound findings. It may help find early warning signs of a stroke before it happens.
Shanghai, Shanghai MunicipalityAges Any age - NCT07312994Recruiting
How diet affects nerve health proteins
This study looks at levels of two nerve-health proteins in people who follow different diets for at least a year. It may help show how vegan, vegetarian, or omnivorous eating affects your brain and nerves over time.
Salzburg, State of SalzburgAges 18–40 - NCT07598487Enrolling by invitation
Physical Therapy Techniques for Stroke Recovery and Balance
This study compares two types of physical therapy to help people regain trunk control and balance after a stroke. Participants will receive either PNF (a hands-on technique using rhythmic movements) or NDT (another hands-on technique focusing on movement patterns) to improve stability.
Faisalabad, Punjab ProvinceAges 40–65 - NCT05214092Enrolling by invitation
Study brain changes after surgery in teens and young adults
This study looks at how a brain area involved in hearing and language contributes to recovery after medically needed surgery. It may help doctors better understand post-op outcomes using language and hearing-related brain measurements.
Pittsburgh, PennsylvaniaAges 13–25 - NCT06889961Recruiting
Daily mixed spice consumption for memory health
This trial tests whether eating a mix of spices every day can help improve memory in older adults with mild memory changes. If you are between 50 and 80 and have no major health conditions, you may be able to join.
Los Angeles, CaliforniaAges 50–80 - NCT07293637Recruiting
Brain activity study of mental planning
This study uses brain imaging to see how people mentally simulate and plan multi-step actions. It may help researchers understand planning in healthy adults.
New York, New YorkAges 18–64 - NCT07571889Recruiting
Numbing spray to reduce Botox injection pain for chronic migraine
This study tests whether a numbing spray applied inside the nose before Botox injections can reduce injection pain in people with chronic migraine. The goal is to make the treatment more comfortable without affecting how well it works.
East Providence, Rhode IslandAges 18 years+ - NCT07307950Recruiting
Testing an app to improve rehab for kids with movement disabilities
This study tests a new app designed to help families and therapists coordinate care for children with movement disabilities. It aims to make rehabilitation easier and more connected across different care settings.
BrestAges 2–25 - NCT06797050Recruiting
Robot helper story for children with movement challenges
This study tests whether interacting with a robot helper named Nao can help children with movement difficulties learn new skills. The robot tells a story and guides activities to improve motor and thinking abilities.
Bosisio Parini, LeccoAges 7–16 - NCT07378332Enrolling by invitation
Memory study using brain stimulation
This trial uses brain stimulation to study how memory works. It may help people undergoing epilepsy monitoring learn more about their memory.
Chicago, IllinoisAges 18 years+ - NCT06328114Enrolling by invitationPhase 2
Brain stimulation for cervical dystonia
This study tests a type of brain stimulation called TMS to see if it can improve neck muscle spasms in people with cervical dystonia. It's for adults who haven't had Botox recently and are not on other treatments.
Durham, North CarolinaAges 18 years+ - NCT05357456Recruiting
Study of brain and memory changes in cortisol-producing adrenal conditions
This study tracks thinking and brain changes over time in people with adrenal findings that produce too much cortisol (a stress hormone) on their own. It may help doctors understand how different treatments or watchful waiting affect the brain and cognition.
Nanjing, JiangsuAges 20–65 - NCT06971224RecruitingPhase 2
Can a vitamin B3 supplement improve sleep?
This study tests whether a daily supplement called nicotinamide riboside (a form of vitamin B3) can improve sleep quality in healthy adults. If you are between 40 and 60 years old, have normal sleep, and are not taking sleep aids, you may be able to join.
BergenAges 40–60 - NCT06510842Recruiting
Draining bleeding in the brain with a spinal tube
This study tests a tube placed in the lower back to help drain extra fluid caused by bleeding in the brain. It may help improve recovery after a stroke or brain bleed.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT05801861Recruiting
Brain stimulation study for goal-based navigation skills
This study tests whether noninvasive brain stimulation can improve how people plan and navigate toward a goal. It also uses brain scans and questionnaires to see who may benefit and whether the stimulation is safe for you.
Newark, New JerseyAges 18–55 - NCT07290738Recruiting
TMS for negative symptoms in schizophrenia
This study tests whether a non-invasive brain stimulation technique called TMS can help reduce negative symptoms in people with schizophrenia. These symptoms include things like lack of motivation, limited speech, and not expressing emotions.
Houston, TexasAges 18–60 - NCT07289477RecruitingPhase 1
Study of NouvNeu001 for Multiple System Atrophy
This study tests a new injection called NouvNeu001 for people with Multiple System Atrophy (MSA). The goal is to see if it can help control symptoms that standard treatments aren't managing well.
Beijing, Beijing MunicipalityAges 30–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.