Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07617506Recruiting
Brain Activity Study During Memory Tasks
This research studies how your brain works during memory tasks by safely recording brain activity you're already having monitored. The study may help doctors better understand how memory works and improve treatment for brain conditions.
Nashville, TennesseeAges 18 years+ - NCT07619560Recruiting
Probiotic Cocktail to Slow Early Parkinson's Disease
This study tests whether a special blend of probiotics (good bacteria), an amino acid called tryptophan, and branched-chain amino acids can help slow the progression of early-stage Parkinson's disease. The idea is that these supplements may work through your gut bacteria to help protect your brain.
TaipeiAges 30–85 - NCT07617441Recruiting
Brain and Psychology Study of Hard-to-Treat Migraines
This research study compares brain structure and psychological traits in people with chronic migraines that don't respond well to standard treatments versus healthy volunteers without migraines. Understanding these differences may help doctors develop better treatment options for difficult-to-treat migraines.
Catanzaro, CatanzaroAges 18–75 - NCT06703320Recruiting
Virtual reality pathfinding study for stroke recovery
This study uses a virtual reality pathfinding game to see how your brain activates after a stroke. It may help doctors understand how to improve recovery.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06703307Recruiting
Brain markers for stroke-related thinking changes
This study uses a special brain scanning technique (fNIRS) to look for markers that show how stroke affects thinking. Both people who have had a stroke and healthy volunteers can join.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT07615400Recruiting
Long-term study of people with fucosidosis
This study follows people with fucosidosis over time to learn more about how the condition progresses. It is an observational study, so participants do not receive any new treatment—just regular health monitoring to help researchers better understand the disease.
Orange, CaliforniaAges Any age - NCT07620470Recruiting
Brain Tumor Imaging Study Using Advanced CT Scans
This study examines how a specialized CT scanner (Spectral CT) captures detailed images of brain tumors. Researchers will review your imaging scans to understand how well this technology helps doctors see and understand brain tumors.
Wuhan, HubeiAges 18 years+ - NCT07613710RecruitingPhase 1
Safety study of Lu AH69593 for healthy adults or narcolepsy
This study tests whether a new medication called Lu AH69593 is safe and well-tolerated in healthy adults and people with narcolepsy type 1. Researchers want to understand how the drug affects the body and whether it could help treat excessive daytime sleepiness.
HelsinkiAges 18–64 - NCT07615491Recruiting
Safety and effectiveness study of spinal implants and bone materials
This study tracks how well spinal implants (Titania systems) and bone-filling materials (BONEGRAFT) work after surgery and whether patients experience any problems. Researchers will follow patients after cervical or lower spine surgery to confirm these devices are safe and effective in real-world use.
IzmirAges 18 years+ - NCT07616128RecruitingPhase 2
Testing EVO756 to prevent migraines in adults
This study tests a new medication called EVO756 to help prevent migraines in adults who haven't had success with other preventive treatments. Researchers want to see if this new drug can reduce how often migraines happen.
Chandler, ArizonaAges 18–64 - NCT07617688RecruitingEarly Phase 1
PET imaging tracer safety study in healthy volunteers
This early-stage study tests a new PET imaging agent (a radioactive tracer used in medical imaging) to understand how it moves through the body and the radiation dose it delivers. Researchers need healthy volunteers to help establish whether this imaging tool is safe for future patient use.
New Haven, ConnecticutAges 18–60 - NCT06706687Recruiting
Brain imaging and epigenetics in frontotemporal dementia and bipolar disorder
This study uses brain scans and genetic tests to understand the differences between behavioral variant frontotemporal dementia (bvFTD) and bipolar disorder. It may help improve diagnosis and find better treatments for both conditions.
Milan, MIAges 18 years+ - NCT05674552RecruitingPhase 2/Phase 3
Ketone drinks to treat hard-to-stop seizure emergencies
This trial tests whether taking ketone esters (a special form of ketones) can help stop refractory generalized convulsive status epilepticus (a seizure emergency that is hard to control). If you qualify, the study team will check safety closely, especially your breathing, heart stability, and blood sugar/acid levels.
SohagAges 1–10 - NCT05670847RecruitingPhase 2/Phase 3
Ketone drinks for drug-resistant epilepsy
This trial tests whether taking “ketone ester” supplements can reduce seizures in people with drug-resistant epilepsy. It may help by changing how the brain uses energy, but you must meet several safety and diet-related conditions.
SohagAges 1–16 - NCT05959746Recruiting
AI video tool study for early stroke and TIA diagnosis
This study collects short video and clinical information from people being checked for stroke or a “mini-stroke” (TIA) soon after symptoms start, to help build an AI diagnostic tool. You may be contacted again for a follow-up visit within about 4 months.
Nîmes, GardAges 18 years+ - NCT06132399Recruiting
Virtual reality software for recent stroke recovery
This trial tests whether using virtual reality exercises can help people who recently had a stroke regain movement in their arms or legs. If you had a stroke 7 to 14 days ago and have weakness on one side, this study may help with your recovery.
Almería, AlmeríaAges 18 years+ - NCT06473987Recruiting
Virtual reality training for better walking after brain injury
This trial tests a virtual reality program that combines thinking and walking exercises to help improve your balance and walking speed. It may be a good fit if you have a traumatic brain injury and walk more slowly than usual.
West Orange, New JerseyAges 18–65 - NCT06481176Recruiting
How exercise affects blood in restless legs syndrome
This trial studies how a single session of exercise changes blood markers in people with restless legs syndrome (RLS) who are not currently being treated. If you have moderate to severe RLS and are not regularly active, this study may help us understand how exercise affects your condition.
Stanford, CaliforniaAges 18 years+ - NCT06587308Recruiting
How pressure garments affect arm function after stroke
This study tests whether wearing special pressure garments on the arm can improve movement, feeling, and quality of life for people who have had a stroke. It may help if you have some arm weakness but not too much tightness or other health problems.
Weifang, ShandongAges 18–80 - NCT06695312Recruiting
High Tone Power Therapy for Neck Pain and Body Awareness
This trial tests a type of physical therapy called High Tone Power Therapy for people with long-term neck pain from a herniated disc in the neck. It aims to reduce pain and improve your sense of where your neck is in space (proprioception) without needing surgery.
Giza, Giza GovernorateAges 35–50 - NCT06708078Recruiting
Study on extra health support for unruptured brain aneurysm
This study looks at whether having extra check-ins with health professionals (like nurses or therapists) can help people living with an unruptured brain aneurysm. If you have a newly found or monitored aneurysm and no history of a rupture, you may be able to join.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT06707454Recruiting
Recovery after open heart surgery in older adults
This study looks at how older adults recover after open heart surgery, focusing on brain and nerve health. It may help researchers understand the effects of surgery on thinking and memory.
CairoAges 60 years+ - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT03888924RecruitingPhase 2
BCG vaccine for people with radiologically isolated syndrome
This trial tests whether a BCG vaccine can help people who have radiologically isolated syndrome (RIS), a condition where MRI scans show signs of possible multiple sclerosis before symptoms develop. The study aims to see if vaccination is safe and can change disease behavior over time.
RomeAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.