Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07730879Recruiting
Wall Squat Exercise for Blood Pressure in Sleep Apnea
This study tests whether a simple wall squat exercise can help lower blood pressure in people who have both high blood pressure and sleep apnea (treated with CPAP). If you are using CPAP regularly and are otherwise healthy enough to exercise, this trial may be a good fit for you.
BragaAges 18–80 - NCT06744920RecruitingPhase 3
New drug for generalized myasthenia gravis
This trial tests a new medication (remibrutinib) versus a placebo to see if it helps adults with generalized myasthenia gravis. You may qualify if your symptoms affect multiple parts of your body and you haven't had certain recent treatments.
Phoenix, ArizonaAges 18–85 - NCT07733284RecruitingEarly Phase 1
Home walking program to boost thinking skills after TBI
This study tests whether a home-based walking program can improve thinking skills like memory and attention in people with traumatic brain injury (TBI). Eligible participants are 18 to 65, can walk briskly without help, and have noticed problems with thinking since their injury.
East Hanover, New JerseyAges 18–65 - NCT06088355Recruiting
Comparing exercise amounts for moderate Parkinson's
This study compares two different amounts of light-to-moderate exercise to see which is better for people with moderate Parkinson's disease. It involves walking or doing similar activities at a comfortable pace, either a moderate amount or a higher volume, over several weeks.
Decatur, GeorgiaAges 40 years+ - NCT03911388RecruitingPhase 1
HSV G207 for Children with Recurrent Cerebellar Brain Tumors
This trial is testing a virus called HSV G207, which is injected directly into the tumor, to treat children and young adults with a type of brain tumor in the cerebellum that has come back or not responded to standard treatments.
Birmingham, AlabamaAges 3–22 - NCT07733752Recruiting
AI symptom-checking for spine pain in physical therapy
This trial tests if a computer tool that checks your symptoms before a visit can help you and your physical therapist make better decisions about your spine care. It is for adults with neck, mid-back, or low back pain (with or without leg pain) who are starting physical therapy.
AsyutAges 18 years+ - NCT07734103RecruitingPhase 2
Lumateperone for Adult Stuttering
This study tests whether the drug lumateperone can help adults with stuttering, a speech disorder that began in childhood. If you have moderate or severe stuttering, this treatment might reduce symptoms.
Costa Mesa, CaliforniaAges 18–65 - NCT07695701RecruitingPhase 4
Heart imaging study for a new ATTR-CM treatment
This trial uses heart scans to see how the drug acoramidis affects heart structure and function in people with a specific type of heart disease called ATTR cardiomyopathy. It may help doctors understand if the treatment is working.
St Louis, MissouriAges 18–80 - NCT07140614RecruitingPhase 1
Study of EDK060 for adults with CMT1A
This trial tests a new medicine called EDK060 for people with Charcot-Marie-Tooth disease type 1A (CMT1A). The study will check if the drug is safe and how the body processes it, with the goal of finding better treatments for this condition.
Ottawa, OntarioAges 18–60 - NCT05851391RecruitingPhase 2
Test drug treatment to stop hard-to-control seizures after cardiac arrest
This Phase 2 trial tests a medication strategy to stop “refractory status epilepticus,” a severe seizure condition that can happen after a cardiac arrest. It may help by reducing ongoing seizure activity after return of circulation in the ICU.
San Francisco, CaliforniaAges 18 years+ - NCT06638944RecruitingPhase 2
Wearable device training for swallowing after stroke or Parkinson's
This study tests a wearable device that gives feedback on swallowing exercises. It may improve swallowing safety after a stroke or for people with Parkinson's disease.
Champaign, IllinoisAges 50–90 - NCT07374419RecruitingPhase 1/Phase 2
Atamparib for advanced lung cancer with KRAS mutation
This trial tests a drug called Atamparib for people with advanced lung cancer that has a specific genetic change called a KRAS mutation. It is for patients whose cancer has continued to grow after at least one standard treatment.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07322003RecruitingPhase 3
Pridopidine for ALS: Phase 3 trial testing safety and effectiveness
This trial is testing if an oral medication called pridopidine can slow the progression of ALS. It is for people recently diagnosed with ALS who have mild to moderate breathing function and meet specific risk scores.
Phoenix, ArizonaAges 18–80 - NCT06623994Recruiting
Epilepsy care access study in Kenya
This trial tests a program to help people with epilepsy in Kenya who are not taking their medication regularly get better access to care and support.
EldoretAges 12 years+ - NCT07324694Recruiting
Stable blood pressure during heart surgery and recovery
This study looks at how changes in blood pressure during heart surgery affect recovery. If you are having scheduled heart surgery with a heart-lung machine, you may be able to join.
Diyarbakır, DiyarbakırAges 18 years+ - NCT07660263Recruiting
Predicting dementia after stroke with genetics and imaging
This study aims to develop a tool that predicts the risk of dementia after a stroke using genetic and imaging data. It enrolls both healthy adults and people who have had a stroke in the last 3 years.
Gyeonggi-do, Gyeonggi-doAges 19 years+ - NCT07083986Enrolling by invitation
Surgery vs stenting for recent stroke patients
This trial compares two procedures to open a blocked carotid artery in people who recently had a stroke. One option is surgery (carotid endarterectomy) to remove the blockage, the other is stenting (placing a small mesh tube to hold the artery open). The goal is to see which works better for patients still having some stroke symptoms.
MoscowAges 18 years+ - NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Scottsdale, ArizonaAges 41–81 - NCT06790095Enrolling by invitationPhase 2
Testing Cyclosporine for Moderate to Severe Brain Injury
This study tests a drug called cyclosporine to see if it can help people with moderate to severe traumatic brain injury. You may be eligible if you have a brain injury seen on CT and can start treatment within 24 hours.
San Francisco, CaliforniaAges 18–65 - NCT07225504RecruitingPhase 3
Study of remibrutinib for secondary progressive multiple sclerosis
This trial tests an oral medication called remibrutinib to see if it can slow disability progression in people with secondary progressive multiple sclerosis (SPMS). You might join if you have had MS for a while, your symptoms have worsened over the past year, and you haven't had any recent relapses.
Birmingham, AlabamaAges 18–65 - NCT02316314Recruiting
Study heart scan and function in people with Friedreich’s ataxia
This study uses heart tests (including ultrasound and MRI) to better understand how Friedreich’s ataxia affects the heart. You might benefit by getting detailed heart evaluation and contributing to research that could guide future care.
New York, New YorkAges 12–50 - NCT07732868Enrolling by invitation
Virtual Reality Therapy for Spinal Cord Injury
This trial tests a virtual reality (VR) program that uses brain-machine interface (BMI) technology to help people with spinal cord injuries regain movement. The program may help your brain and body work together better, potentially improving your recovery.
AveiroAges 18–65 - NCT07555119Recruiting
Home Sleep Testing: Night-to-Night Measurement Variability Study
This study measures how sleep breathing patterns vary from night to night using home sleep testing. It helps researchers understand if portable sleep tests give consistent and reliable results.
BernAges 18 years+ - NCT07179822Recruiting
Brain retraining for wrist movement after spinal cord injury
This trial tests whether a brain-training technique that uses small electrical pulses can help improve wrist movement in people with spinal cord injury. It is designed for those who have some wrist weakness but can still produce a tiny electrical signal in the wrist muscle.
Charleston, South CarolinaAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.