Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT04920318Recruiting
Study to improve language in primary progressive aphasia
This trial looks at ways to improve language abilities in people with primary progressive aphasia (a long-term brain condition that affects speech and language). It may help if your communication problems come from this condition and you can safely take part in the study activities, which likely involve language practice and MRI scanning.
Tucson, ArizonaAges 45–80 - NCT06612853Recruiting
Sleep Quality Scale Validation for Spine Patients
This study tests a single question about sleep quality to see if it works well for people with spine problems. You will fill out a simple questionnaire and may help improve how sleep is measured in future spine care.
Zurich, Canton of ZurichAges 14 years+ - NCT06709950Recruiting
Art therapy for movement recovery after stroke
This study tests art therapy (like painting or clay) to help improve movement and emotional well-being after a recent stroke. It is designed for people in the subacute phase (2 weeks to 3 months after their first stroke) who have mild to moderate physical challenges and can actively participate in creative activities.
Jiamusi, HeilongjiangAges 40–75 - NCT06709690Recruiting
AI-powered PET/MR scanner for children with suspected cancer
This study tests a new, fast, and quiet AI-powered PET/MR scanner to take detailed pictures of children with suspected cancer. It aims to make the imaging experience easier and more comfortable for kids.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07609914RecruitingPhase 4
Safety study of an extra dose of rimegepant for migraine
This study tests whether taking an additional dose of rimegepant (a migraine medicine you may already use) is safe and helpful for adults with migraine. Rimegepant is a calcitonin gene-related peptide (CGRP) receptor antagonist—a type of medicine that blocks a protein involved in migraine pain.
Canoga Park, CaliforniaAges 18 years+ - NCT07604116RecruitingPhase 1
Testing a new imaging agent for Parkinson's and related conditions
This study tests an investigational imaging agent called SST001, which may help doctors see a protein linked to Parkinson's disease (PD) and multiple system atrophy (MSA) in the body. It will be given to healthy volunteers and patients with PD or MSA to check safety, how it spreads, and how the body handles it.
Wuxi, JiangsuAges 18 years+ - NCT07609719RecruitingPhase 4
Switch to under-the-skin ocrelizumab for multiple sclerosis
This trial tests a new way of taking Ocrelizumab as a shot under the skin, for people with MS who are already on a similar treatment and want to switch. The goal is to see if switching is safe and works well.
Scottsdale, ArizonaAges 18–65 - NCT07603752Recruiting
Brain implant to restore arm movement in spinal cord injury
This trial tests a wireless implant placed on the brain's surface to help people with cervical (neck-level) spinal cord injuries regain some arm and hand movement. The device reads brain signals and sends them to muscles, potentially bypassing the damaged spinal cord.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07609108RecruitingPhase 3
Pridopidine to slow Huntington's disease progression
This study tests whether a medication called pridopidine can help slow the progression of Huntington's disease symptoms in adults. Huntington's is a genetic disorder affecting movement, mood, and thinking, and this trial aims to see if pridopidine improves daily functioning and quality of life.
Birmingham, AlabamaAges 23–65 - NCT07610564RecruitingPhase 1
Testing a New Treatment for Multifocal Motor Neuropathy
This study tests a new medicine called empasiprubart in adults with multifocal motor neuropathy (MMN), a rare condition affecting nerve function. The trial uses ultrasound to see if the medicine can help reduce nerve thickening and improve symptoms.
Tbilisi, K'alak'i T'bilisiAges 18 years+ - NCT07608432RecruitingPhase 3
Testing a New DMD Treatment Given Every 4 Weeks
This study tests whether a new medicine called zeleciment rostudirsen can help ambulatory (walking) males with Duchenne muscular dystrophy (DMD). The medicine is given as an intravenous infusion (through a vein) every 4 weeks and works by helping the body produce a protective muscle protein.
Hillsborough, North CarolinaAges 4–18 - NCT03660917RecruitingPhase 2/Phase 3
Riluzole treatment for SCA7 nerve balance problems
This trial studies whether riluzole can help people with spinocerebellar ataxia type 7 (SCA7), a genetic condition that affects balance and coordination. It may help slow symptoms or improve daily function, and you’d be closely monitored for side effects.
RomeAges 7 years+ - NCT05995782RecruitingPhase 1
Testing safety of FB418 in healthy people
This trial studies a new drug called FB418 to see if it's safe and how the body handles it. It first tests single doses in younger healthy men, then multiple doses, and also includes an optional group for healthy older adults.
SeoulAges 19 years+ - NCT05877560Recruiting
Noninvasive brain stimulation for eye focusing trouble
This study tests a noninvasive brain stimulation treatment to improve symptoms of convergence insufficiency, a condition that makes near vision tasks like reading harder. You may be randomly assigned to the study treatment or a comparison condition.
Downers Grove, IllinoisAges 18–40 - NCT06224426Recruiting
Oxygen Levels for Stroke Patients Having Clot Removal
This trial tests whether giving a specific level of oxygen during a procedure to remove a stroke clot improves recovery. It is for people with a moderate to severe stroke in the front part of the brain, treated within 24 hours of symptoms starting.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07605858Recruiting
Epilepsy, Sleep, and Brain Activity Study
This study examines how seizures affect sleep quality and dreams in people with hard-to-treat focal epilepsy. Researchers will use specialized brain electrodes to understand these connections during sleep, which may help improve treatment in the future.
Durham, North CarolinaAges 18–55 - NCT07608380Enrolling by invitation
Custom Guides for Cheekbone and Upper Jaw Fracture Surgery
This trial tests whether using a personalized surgical guide and custom plate helps surgeons repair cheekbone and upper jaw fractures more accurately. The goal is to improve how well the bones heal and how your face looks after surgery.
CairoAges 18 years+ - NCT07609394Recruiting
Duchenne and Becker Muscular Dystrophy Health Records Study
This study collects electronic health records (medical information already in your doctor's computer system) from people with Duchenne or Becker muscular dystrophy, or female carriers of these conditions. Researchers will use this data to better understand the diseases and improve care over time.
Little Rock, ArkansasAges Any age - NCT07605013Recruiting
Neck Exercises for Office Workers: Building Strength and Function
This study tests whether specific neck mobilization techniques (gentle movements and stretches) can improve neck strength and function in desk workers. You would be a healthy control participant to help researchers understand how these techniques work in people without existing neck pain.
IstanbulAges 18–40 - NCT07609966Recruiting
Virtual Reality for Stroke Arm Recovery
This trial tests whether virtual reality exercises help stroke patients recover arm and hand movement faster and better. You'd use VR games alongside your regular rehabilitation therapy in the hospital and after going home.
GironaAges 18 years+ - NCT07609433Recruiting
Reducing Heat and Air Pollution Exposure in Pregnant Women
This study helps pregnant women in their second trimester reduce exposure to heat and air pollution through monitoring and personalized advice. Researchers want to see if reducing these environmental stressors improves pregnancy health outcomes.
LimassolAges 20–35 - NCT07604688Recruiting
Registry Study of Dural Arteriovenous Fistulas in China
This study collects information from patients diagnosed with abnormal blood vessel connections in or around the brain or spine. Researchers will track your diagnosis, treatment, and outcomes to better understand these conditions and improve care.
BeijingAges 18 years+ - NCT07606300Recruiting
Light Training to Help Light Sensitivity After Head Injury
This trial tests whether a training program using colored light targets can help reduce light sensitivity (photophobia) that some people experience after a traumatic brain injury. The training involves focusing your eyes on lights during several visits.
Columbus, OhioAges 18–80 - NCT07611136Recruiting
Brain Vessel Disease Progression After Different Stroke Types
This study examines how small blood vessel disease in the brain progresses differently depending on whether you've had a recent stroke. Researchers will use MRI scans to track changes over time and better understand this condition.
Ulm, Baden-WurttembergAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.