Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07716540Recruiting
Pain relief injection for hip fracture surgery
This study tests whether a special numbing injection (deep iliacus plane block) can better control pain after hip fracture surgery. If you're having hip surgery under spinal anesthesia, researchers want to see if this extra block helps you recover with less pain.
Istanbul, IstanbulAges 18 years+ - NCT07336277RecruitingPhase 3
Sleep quality study for hospitalized orthopedic trauma patients
This study tests if a special sleep program can help people with leg or foot injuries sleep better in the hospital. It may show if treatments like zolpidem or melatonin help improve sleep after surgery.
Atlanta, GeorgiaAges 18–65 - NCT07533942RecruitingPhase 2
Testing JZP3507 for Recurrent Grade 2 or 3 Brain Tumors
This study tests a new drug called JZP3507 for people with meningioma (a type of brain tumor, grades 2 or 3) that has come back or grown despite previous treatment. The goal is to see if this medication can slow or shrink the tumor.
San Francisco, CaliforniaAges 18 years+ - NCT07695987Recruiting
Nerve block for pain relief after back surgery
This trial tests a nerve block called Quadro-Iliac Plane Block to reduce pain after a single-level lumbar microdiscectomy (back surgery). The block is given before surgery and may help you need less pain medicine and recover more comfortably.
Istanbul, IstanbulAges 18–75 - NCT07049744Recruiting
Nerve stimulation for adults with obstructive sleep apnea
This trial tests a device that stimulates a nerve to keep your airway open during sleep. It might help if you have moderate to severe obstructive sleep apnea and cannot use a CPAP mask.
Canberra, Australian Capital TerritoryAges 21 years+ - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Birmingham, AlabamaAges 18 years+ - NCT07472231Recruiting
Game-based therapy for children with lazy eye
This trial tests if a fun, game-based training program can improve vision in children with lazy eye caused by a difference in glasses prescription between the two eyes. It is designed for children ages 4 to 7 who can participate in vision exercises.
Shanghai, Shanghai MunicipalityAges 4–7 - NCT06972056RecruitingPhase 4
Comparing migraine prevention drugs: atogepant, propranolol, topiramate
This study compares three common migraine prevention medications to see which works best. You might be able to join if you have migraines at least 4 days a month and haven't taken these specific drugs before.
Flagstaff, ArizonaAges 18–70 - NCT07414680Recruiting
Healthy aging study for adults 40+ in Taiwan
This study looks at how to help people age healthily. It is for adults 40 and older who are connected to Chang Gung Memorial Hospital in Taiwan. You will provide health information and may have some tests to track your well-being over time.
TaipeiAges 40 years+ - NCT07039916RecruitingPhase 3
Study of IMVT-1402 for mild to severe generalized myasthenia gravis
This trial tests an investigational drug called IMVT-1402 to see if it improves symptoms in people with generalized myasthenia gravis (gMG). If you have mild to severe gMG and are looking for new treatment options, this study may be a fit.
Huntsville, AlabamaAges 18–80 - NCT06635811Recruiting
Circadian-adjusted deep brain stimulation for essential tremor
This study tests whether adjusting the timing of your deep brain stimulation (DBS) based on your body's natural daily rhythms can better control essential tremor. If you have a Medtronic Percept DBS device, you may be able to join.
Gainesville, FloridaAges 21–89 - NCT06769178Recruiting
Virtual reality for balance in young adults with cerebral palsy
This trial tests whether virtual reality exercises can improve balance in people with cerebral palsy. It is designed for young adults who can walk independently and have spasticity on one side of the body.
Istanbul, AtaşehirAges 18–30 - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT05503225RecruitingPhase 2
Colchicine for narrowed brain arteries after recent stroke
This Phase 2 trial tests whether colchicine can help people with significant narrowing in brain arteries (from atherosclerosis) after a recent stroke or “mini-stroke.” It aims to reduce the risk related to this condition during the early period after symptoms begin.
Hong KongAges 40–80 - NCT07630545RecruitingPhase 1
Testing a new drug for Parkinson's disease
This study tests an experimental drug, MTX325, in people with Parkinson's disease. The goal is to see if it is safe and how the body processes it, which may lead to new treatment options.
AdelaideAges 18–75 - NCT07734506Recruiting
Muscle thickness and sarcopenia in stroke survivors
This study looks at how thigh muscle thickness measured by ultrasound relates to muscle weakness and fear of movement in people who have had a stroke. It may help find better ways to assess muscle health and recovery.
Istanbul, IstanbulAges 40–80 - NCT07732530Recruiting
Acupoint Stimulation and Exercise for Pre-Frail Older Adults
This study tests whether combining acupoint stimulation (a type of pressure on specific body points) with exercise can help older adults who are starting to become frail. It aims to improve strength and daily function.
TainanAges 50 years+ - NCT07732972Recruiting
Brain and nerve effects of spinal cord stimulation study
This study uses special recordings to understand how a temporary spinal cord stimulator (a device that sends mild electrical pulses) changes brain and nerve activity in people with chronic pain or spinal cord injury. It aims to find out how the stimulation helps the nervous system work better.
Hualien CityAges 20–70 - NCT07732842Recruiting
Understanding Repetitive Behaviors in Alzheimer's Disease
This study looks at repetitive behaviors (like pacing, tapping, or repeating words) in people with Alzheimer's disease. They want to understand these behaviors better, which could help improve care and treatment.
Limoges, New AquitaineAges 18 years+ - NCT07477431RecruitingPhase 2
Testing levetiracetam for those at risk of Alzheimer's
This trial tests if a medication called levetiracetam (a drug usually used for seizures) can help protect memory in people who are at higher risk for Alzheimer's but do not yet have memory problems. It involves brain scans and cognitive tests to see if the drug can reduce overactive brain activity linked to memory loss.
Toronto, OntarioAges 55–85 - NCT07734181Recruiting
Music Therapy for Parkinson's Disease
This trial tests whether music therapy can help people with Parkinson's disease. It might improve movement, mood, or quality of life.
Arlesheim, Basel-LandschaftAges 50–79 - NCT07732907Recruiting
Study of PML risk in MS patients taking Zeposia
This study looks at people with multiple sclerosis who have taken Zeposia (ozanimod) and later developed a rare brain infection called PML. The goal is to understand how often this happens and to confirm cases.
Lawrenceville, New JerseyAges Any age - NCT07732764Recruiting
TENS for Pain After Chest Surgery
This trial tests if a mild electrical therapy (TENS) can reduce pain after chest surgery. It may help you need less pain medicine and feel better during recovery.
Kaohsiung City, Kaohsiung CityAges 15–85 - NCT07734584Recruiting
Reducing air bubbles during aortic repair with carbon dioxide
This trial tests a special flushing method using carbon dioxide gas to prevent air bubbles from entering the bloodstream during a procedure to fix the main artery in the chest. This could help avoid strokes or other complications.
Bologna, ItalyAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.