Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07411664Enrolling by invitation
Balance and walking study for stroke, Parkinson's, or multiple sclerosis
This study uses special motion-tracking tools to measure balance and trunk control in people with first-time stroke, Parkinson’s, or multiple sclerosis. It aims to understand how these conditions affect stability, which could help tailor rehabilitation.
Kaposvár, Somogy CountyAges 18–80 - NCT07599904Recruiting
Real-world study of Medtronic stroke treatment devices
This registry tracks how Medtronic's FDA-approved devices work in treating acute ischemic stroke (a type of stroke caused by a blood clot) in everyday clinical practice. Researchers collect information to understand device safety and effectiveness outside of formal clinical trials.
Flint, MichiganAges 18 years+ - NCT07330258Recruiting
Observing Parkinson's over time in people still having movement symptoms
This study follows people with Parkinson's disease who still have movement symptoms despite taking medication. It aims to understand how the disease changes over time, which could help improve future treatments.
Phoenix, ArizonaAges 45–75 - NCT07547670Recruiting
Brain Stimulation for Lazy Eye in Children
This study tests whether a non-invasive brain stimulation technique called tDCS (transcranial direct current stimulation) can help children with lazy eye (amblyopia) whose vision hasn't improved with traditional patching treatments. The goal is to see if stimulating the brain can boost the weak eye's vision.
MurciaAges 4–14 - NCT07295847RecruitingPhase 1
Study of AZD0120 for autoimmune diseases
This trial tests if a new medication, AZD0120, is safe for people with autoimmune diseases. It aims to help patients by targeting the immune system.
Tucson, ArizonaAges 18–75 - NCT07323121Recruiting
Flickering light therapy for sleep problems in Parkinson's
This study tests whether a special flickering light (40 Hz) can help improve sleep in people with Parkinson's disease. Participants will be exposed to the light at home, and researchers will track changes in sleep quality.
Nanjing, JiangsuAges 50–75 - NCT07731321Enrolling by invitation
Are Earplug Instructions Better One Way Or Another?
This study compares different ways of teaching people how to use earplugs. It will look at which method works best to protect hearing in a noisy workplace.
Chiang MaiAges 20–60 - NCT07299240Recruiting
Arm cuff exercise for better sleep in Parkinson's
This trial tests if a simple, non-invasive arm cuff treatment can improve sleep and other non-motor symptoms in people with early Parkinson's disease. It involves using a blood pressure-like cuff on your arm to briefly restrict blood flow, then release it, hoping to train your body's protective systems.
Nanjing, JiangsuAges 50–70 - NCT07442747RecruitingPhase 2
Aerobic exercise benefits in Parkinson's with DBS
This trial tests whether aerobic exercise (like walking or biking) can improve brain function in people with Parkinson's who have a deep brain stimulation (DBS) device. It may help you learn how exercise affects your symptoms and DBS treatment.
Cleveland, OhioAges 18 years+ - NCT06728722Recruiting
Ultrasound for body measurement in critical care
This study uses ultrasound to measure body composition in women admitted to the Obstetrics and Gynecology critical care unit. It aims to see if ultrasound can help assess health status in critically ill patients.
Cairo, Cairo GovernorateAges 16 years+ - NCT07725926Recruiting
Combining therapy techniques for tic-like OCD
This study tests a therapy that combines two approaches—one for tics and one for OCD—to help people whose OCD feels like it's linked to tics. The goal is to see if this combined treatment reduces distressing urges and repetitive behaviors.
London, LondonAges 18–65 - NCT05552157RecruitingPhase 2/Phase 3
Study of treatments for early onset Alzheimer's caused by genetic mutations
This trial tests potential treatments for people who are at risk for or have early onset Alzheimer's disease due to a specific genetic mutation. It aims to find treatments that could slow or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06081348RecruitingPhase 2
Sertraline vs. placebo for anxiety in kids with developmental disorders
This trial compares sertraline (a common antidepressant) to a placebo (a pill with no medicine) to see which better reduces anxiety in children and teens who also have a neurodevelopmental disorder like autism, ADHD, or Tourette's. The goal is to help you and your child understand if this treatment might offer relief from anxiety.
Calgary, AlbertaAges 8–17 - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT07729449Recruiting
Predicting headache after cesarean using ultrasound and oxygen monitoring
This trial measures how well two monitoring tools (optic nerve ultrasound and brain oxygen levels) can predict headache after a planned cesarean. It may help find better ways to prevent post-dural puncture headache.
Ordu, AltinorduAges 18–40 - NCT07728539Recruiting
Comparing a faster ablation method for atrial fibrillation
This study compares a newer, faster type of ablation (high-power short-duration) with the standard approach for treating atrial fibrillation. The goal is to see which method is safer and more effective at restoring a normal heart rhythm.
MoscowAges 18–70 - NCT07107022Recruiting
Study of Penumbra System for acute ischemic stroke
This study is collecting information on how well the Penumbra System works and how safe it is when used to remove blood clots in people having a certain type of stroke. It is for patients who are eligible for mechanical thrombectomy (a procedure to remove the clot) using this device as the first treatment.
Nedlands, Western AustraliaAges 18–80 - NCT06999122Recruiting
Testing a new helmet-style brain scanner for stroke bleeding
This trial tests a new type of brain scanner (similar to a helmet) that looks for bleeding in the brain without radiation. It is for people who have had stroke-like symptoms in the last 24 hours and have not yet received treatment.
Los Angeles, CaliforniaAges 22 years+ - NCT07728032Recruiting
How diet and medicine affect gut health in PKU children
This study looks at how a phenylalanine-restricted diet or certain PKU medicines affect gut health in children with PKU. It also includes healthy siblings or household members as a comparison group.
Birmingham, BirminghamAges 3–17 - NCT07089121RecruitingPhase 1/Phase 2
Descartes-08 for young people with autoimmune diseases
This trial tests a new therapy called Descartes-08 for children, teens, and young adults with autoimmune conditions like lupus, myasthenia gravis, or dermatomyositis. It aims to see if it can help control moderate disease that hasn't responded well enough to other treatments.
Washington D.C., District of ColumbiaAges 12 years+ - NCT07729735Enrolling by invitation
Physiotherapy after breast reduction surgery
This study tests whether adding physical therapy after breast reduction surgery helps you recover faster and feel better. You must be between 18 and 50, have had cosmetic breast reduction, and be free of certain health conditions like arm swelling or nerve problems.
IstanbulAges 18–50 - NCT06951698RecruitingPhase 3
Testing KarXT for bipolar I mania
This trial tests a new medicine, KarXT, to see if it can safely treat manic episodes in people with bipolar I disorder. It is for patients who are currently hospitalized for a manic episode that started within the last 3 weeks.
Bentonville, ArkansasAges 18–65 - NCT05194930Recruiting
Insomnia treatment study for Veterans with PTSD symptoms
This study tests treatments to help Veterans who have both PTSD symptoms and trouble sleeping (insomnia). You may be invited to try study procedures to see what helps insomnia and whether it also improves sleep-related well-being.
Sepulveda, CaliforniaAges 18 years+ - NCT06849076Recruiting
Ankle joint motion and body awareness after stroke
This study tests if a hands-on ankle treatment can improve your sense of where your ankle is in space (proprioception) after a stroke. It looks at how well you can feel and control your ankle movement.
Bolu, MerkezAges 45–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.