Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,606 recruiting studies in this area right now.
By phase
- Not applicable4,686
- Phase 21,188
- Phase 1568
- Phase 3457
- Phase 1/Phase 2368
- Phase 4229
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer479
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Hepatocellular Carcinoma (HCC)114
- Colon Cancer112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Chinese University of Hong Kong56
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona190
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,606 total
- NCT07201194Recruiting
Acupuncture for chemotherapy nausea
This trial tests if acupuncture can help reduce nausea in people who still feel sick despite taking their regular anti-nausea medication during chemotherapy.
VejleAges 18 years+ - NCT07202559Recruiting
Preventing Pancreatitis After Shock Wave Therapy for Pancreatic Stones
This study tests whether a combination of an NSAID (indomethacin) given rectally plus extra fluids through an IV can prevent pancreatitis after shock wave therapy for pancreatic stones. It may help reduce inflammation and protect your pancreas during treatment.
BaotouAges 18–85 - NCT07198581Recruiting
Using AI to manage chemotherapy side effects
This trial tests if an AI-powered system can help monitor and manage side effects during chemotherapy for breast or colorectal cancer. If you are starting chemotherapy and can report your symptoms, this study may offer extra support.
IncheonAges 18 years+ - NCT07193836Enrolling by invitation
Lidocaine for easier recovery after laparoscopic surgery
This study tests whether giving lidocaine (a numbing medicine) through an IV can help you wake up more smoothly and with less discomfort after laparoscopic gallbladder or gynecologic surgery. If you are generally healthy and having one of these specific surgeries, you may be a good fit.
Yinchuan, NingxiaAges 18–70 - NCT07194616Recruiting
Rectal cancer blood test study before surgery
This trial is studying a blood test (CTC) for people with rectal cancer that hasn't spread to other parts of the body. It aims to see how the test relates to treatment outcomes after surgery.
OlomoucAges 18 years+ - NCT07196735Recruiting
Body composition study for women with functional dyspepsia
This study uses a simple, painless test (bio-electrical impedance) to measure body composition in women with functional dyspepsia (stomach discomfort without a clear cause). It aims to better understand how body makeup relates to symptoms.
BrusselsAges 18–75 - NCT07198386RecruitingPhase 2
Study of CS060380 tablets for NASH (fatty liver disease)
This trial tests an experimental pill called CS060380 for people with NASH (a type of fatty liver disease that can cause liver damage). You may qualify if you have a liver biopsy showing NASH with early-to-moderate scarring, or an MRI showing at least 10% liver fat, and your liver enzymes are stable.
Fuzhou, FujianAges 18–70 - NCT07194005RecruitingPhase 2
Combination therapy for HER2 1+/2+ advanced stomach cancer
This trial tests a new combination of drugs (RC48, sintilimab, and SOX chemotherapy) for people with stomach or gastroesophageal junction cancer that cannot be removed by surgery, has not been treated before, and has a specific HER2 score (1+ or 2+). The goal is to shrink the tumor enough to possibly allow surgical removal.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07195006Recruiting
Malnutrition in pregnancy and child growth study
This study looks at how nutrition during pregnancy affects the health of mothers and babies, including gut health and growth. It compares women with low nutrition to those with healthy nutrition.
HarareAges 18 years+ - NCT07200141RecruitingPhase 2
Boosting radiation before surgery for rectal cancer
This trial tests a new way of giving radiation therapy before surgery for rectal cancer. It uses a higher dose to the tumor during standard radiation to see if it can improve outcomes.
BeijingAges 18–80 - NCT07195331RecruitingPhase 4
Comparing dye doses for clearer bile duct images during gallbladder surgery
This trial tests two different doses of a special dye (indocyanine green) to see which one gives surgeons a clearer view of the bile ducts during gallbladder removal. The goal is to help make the surgery safer and reduce the risk of injury.
Salamanca, SalamancaAges 18 years+ - NCT07201649Recruiting
Liver disease and artery calcification study
This study looks at how liver function and scarring affect calcium buildup in arteries. It may help people waiting for a liver transplant understand these changes.
Nice, Alpes-maritimesAges 18 years+ - NCT07197619Recruiting
Hernia sac removal in paraesophageal hernia repair
This study compares two surgical techniques for fixing a paraesophageal hernia (a type of hiatal hernia). It looks at whether removing the hernia sac affects tension during repair.
Grand Rapids, MichiganAges 18–80 - NCT07198113Recruiting
Comparing newer treatments for pediatric inflammatory bowel disease
This study is for children and teens with inflammatory bowel disease (Crohn's, colitis, or indeterminate) whose previous anti-TNF medicine stopped working. It compares several newer treatments to see which works best.
Chapel Hill, North CarolinaAges 1–18 - NCT07199127Recruiting
Studying duodenal polyps in FAP
This study reviews duodenal polyps in people with FAP to improve how they are classified. It uses existing medical records from endoscopies (scope tests) to help doctors better understand and manage polyp growth.
Milan, MIAges 18 years+ - NCT07198568Recruiting
Swallowing and Neck Muscle Activity in Sarcopenic Dysphagia
This study looks at how the muscles in your neck and throat work when you swallow, specifically in older adults who have both sarcopenia (low muscle mass) and trouble swallowing. The goal is to better understand the connection between swallowing and muscle activity, which may help develop better treatments.
Incheon, Jung-guAges 65 years+ - NCT07198165RecruitingPhase 2
Short radiation followed by chemo plus bevacizumab with or without immunotherapy for rectal cancer
This trial tests whether adding an immunotherapy drug (PD-1 inhibitor) to standard chemoradiation and targeted therapy improves outcomes for locally advanced rectal cancer. It is for patients who have not had prior treatment and do not have certain genetic markers (BRAF mutation or MSI-H).
ShanghaiAges 18–75 - NCT07198984Recruiting
Boosting gut bacteria to improve digestive health
This study tests whether boosting certain gut bacteria can improve your gut health. If you're a healthy adult who exercises regularly or eats a flexitarian diet, this trial may be for you.
Jouy-en-JosasAges 20–80 - NCT07195123Recruiting
Testing the SMART IBD app for kids with IBD
This study tests whether a smartphone app called SMART IBD can help children with IBD take their medications more consistently. It is for children who are currently missing more than 1 in 7 doses of their daily or weekly IBD medication.
Cincinnati, OhioAges 13–17 - NCT07195383Recruiting
Safe swallowing check after breathing tube removal in ICU
This study tests a special nutrition program for patients who just had a breathing tube removed in the ICU. It aims to see if a safe swallowing check can help prevent problems and make feeding safer.
IstanbulAges 18 years+ - NCT07194551Recruiting
Checking uterine cancer risk in Lynch syndrome with home sampling
This study is testing a new way to check for uterine cancer risk in people with Lynch syndrome. You would collect a vaginal sample yourself at home and fill out a health questionnaire, which may help catch warning signs early.
Vancouver, British ColumbiaAges 30 years+ - NCT07199491Enrolling by invitation
Healthy lifestyle program for Hispanics with fatty liver disease
This trial tests a culturally tailored lifestyle program for Hispanic adults with fatty liver disease (MASLD). It aims to help improve liver health through diet and activity changes with support from a family member.
Houston, TexasAges 18 years+ - NCT07196410RecruitingPhase 1
A study of KAN-004 for diarrhea or colitis from immunotherapy
This trial tests a new treatment, KAN-004, for people with diarrhea or colon inflammation caused by cancer immunotherapy. It aims to help manage these side effects.
Montreal, QuebecAges 18 years+ - NCT07201012Recruiting
Finding skin tumors in Lynch syndrome patients
This study looks for Muir-Torre syndrome, a condition that causes certain skin tumors, in people who already have Lynch syndrome. It may help doctors understand how common this skin condition is in Lynch syndrome patients.
Nîmes, GardAges Any age
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,606 recruiting gastroenterology studies from the U.S. registry right now, out of 12,023 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.