Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,606 recruiting studies in this area right now.
By phase
- Not applicable4,686
- Phase 21,188
- Phase 1568
- Phase 3457
- Phase 1/Phase 2368
- Phase 4229
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer479
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Hepatocellular Carcinoma (HCC)114
- Colon Cancer112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Chinese University of Hong Kong56
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona190
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,606 total
- NCT07136701Recruiting
Pancreatic neuroendocrine tumor risk factors and prognosis
This study looks at how pancreatic neuroendocrine tumors behave differently in younger versus older people. It aims to find better ways to predict outcomes and guide treatment.
Jinan, ShandongAges 18–85 - NCT07138326Recruiting
Medication absorption in people with an ostomy
This trial looks at how well your body absorbs certain medications if you have an ileostomy or colostomy. It aims to help doctors better understand dosing for people with ostomies.
Vienna, State of ViennaAges 18 years+ - NCT07142798Enrolling by invitation
14-day triple therapy for H. pylori infection
This trial tests a 14-day treatment using bismuth, amoxicillin, and a stomach acid reducer (PCAB) to see how well it clears H. pylori, a bacteria that can cause stomach ulcers. It may be an option if you have H. pylori and haven't had stomach surgery or certain serious health conditions.
Kaohsiung CityAges 18–80 - NCT07139366RecruitingPhase 4
Probiotic plus bismuth combo for stubborn H. pylori
This study tests a combination of a probiotic (Saccharomyces boulardii) plus a standard bismuth-based four-drug treatment for people whose H. pylori infection has not been cured by previous treatments. It aims to see if adding the probiotic helps the treatment work better and cause fewer side effects.
Xi'an, ShaanxiAges 18–75 - NCT07143487Recruiting
Family communication after genetic testing for colon cancer
This trial studies how patients with newly diagnosed colon cancer share genetic test results with their family members. It aims to improve communication and support after learning about hereditary risk.
Anchorage, AlaskaAges 18 years+ - NCT07142226Recruiting
Liquid biopsy for advanced bile duct cancer
This trial uses a blood test called ctDNA to look at the genetic makeup of your cancer. It aims to learn more about bile duct cancer and may help guide your treatment choices.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07137117Recruiting
Phone counseling after sleeve gastrectomy for better health
This study tests whether phone counseling can help you eat better, stay active, and take your medications as prescribed after sleeve gastrectomy weight-loss surgery. If you qualify, you will receive regular calls from a counselor to support your recovery.
Adana, YüreğirAges 18–65 - NCT07141888Recruiting
Probiotic supplement for high uric acid
This study tests whether a probiotic food supplement can lower high uric acid levels, which often cause gout. It might help you if your uric acid is high but you haven't had a recent gout attack.
ÖrebroAges 18–80 - NCT07140679RecruitingPhase 2
Immunotherapy after surgery for certain colon cancers
This trial tests whether giving an immunotherapy drug called toripalimab after surgery can lower the chance of colon cancer coming back. It is for people whose tumors have a specific genetic feature called mismatch repair deficiency (dMMR) and who have had their cancer completely removed.
Atlanta, GeorgiaAges 18 years+ - NCT07139418Recruiting
Studying lymph nodes around the stomach in cancer surgery
This trial studies the importance of checking lymph nodes in the fatty tissue around the stomach during stomach cancer surgery. It helps doctors understand if examining these specific areas can improve treatment decisions.
Hangzhou, ZhejiangAges 18–85 - NCT07144917Recruiting
Immune system changes after Whipple surgery
This study is looking at how the immune system can become weakened after a Whipple procedure for pancreatic tumors. The goal is to better understand and potentially help patients recover more effectively.
LyonAges 18 years+ - NCT07137143Recruiting
Warming the ICU room after abdominal surgery
This study tests how warming the intensive care room after your abdominal surgery affects your recovery. It includes patients who are in the ICU after planned surgery and have no major health problems that affect body temperature.
Adana, YüreğirAges 18 years+ - NCT07142213Recruiting
Studying a two-step liver surgery for liver cancer
This trial looks at a special two-step surgery called ALPPS for people with liver cancer that can't be removed in one operation. The first step helps the liver grow more healthy tissue, and then the second step removes the tumor. The goal is to understand how well this works and how the liver regenerates.
Beijing, Beijing MunicipalityAges 18–75 - NCT06960369RecruitingPhase 1
Brain stimulation and probiotics for diarrhea-predominant IBS
This trial tests whether combining a type of brain stimulation (repetitive transcranial magnetic stimulation) with a probiotic tablet can help people with diarrhea-predominant irritable bowel syndrome. It aims to improve symptoms by targeting both the brain and the gut.
Suzhou, JiangsuAges 18–70 - NCT06961149Recruiting
Comparing light vs dye spray for colon polyp detection
This study compares two methods used during colonoscopy to help find polyps in the colon. It tests whether a special light technique (linked-color imaging) or a dye spray (indigo carmine) works better for spotting adenomas, which are growths that can turn into cancer. If you are at higher risk for colorectal adenomas, this trial may help improve detection.
Jinan, ShandongAges 45–85 - NCT06186752Recruiting
Action planning test for teens with IBD
This study tests if a planning tool helps teenagers with Crohn's disease or ulcerative colitis manage their condition. It's for patients aged 13 to 19 who have had their diagnosis for at least 3 months and are seen at UNC.
Chapel Hill, North CarolinaAges 13–19 - NCT06561529Recruiting
Stomach bypass stent for liver scarring in obese patients
This study tests a stomach bypass stent to treat liver scarring caused by fatty liver disease in people with obesity. If you have obesity and a confirmed liver condition called NASH with moderate scarring, this stent might help you achieve weight loss and improve your liver health.
Riga, RigaAges 18–65 - NCT06945718Recruiting
Green dye test for gastric cancer surgery
This trial tests whether a green dye called indocyanine green can help surgeons find and remove more lymph nodes during laparoscopic surgery for advanced stomach cancer. It may improve the chances of removing all cancer.
Fuzhou, FujianAges 18–75 - NCT06961526Recruiting
Preventing varices bleeding in liver cancer patients on immunotherapy
This trial tests if preventing esophageal varices (swollen veins in the food pipe) can reduce bleeding risk in people with advanced liver cancer who are receiving a combination of two drugs (atezolizumab and bevacizumab). It may help those with good liver function and no high-risk varices at the start.
Tanta, GharbyeaAges 18 years+ - NCT06962670Recruiting
Cancer risk study using digital and molecular markers
This study uses a smartphone app and biological markers to predict cancer risk. It is testing whether digital and molecular data can help identify cancer earlier, especially in women with a history of certain cancers.
Please Refer to Project Homepage For Details (see Link Below), BavariaAges 18 years+ - NCT06961617RecruitingPhase 1
Immune cell therapy for advanced hepatitis B-related liver cancer
This trial tests a new immune cell therapy (LioCyx-M) for people with advanced liver cancer caused by hepatitis B. It uses specially designed T cells (a type of immune cell) that target the hepatitis B virus and may help fight the cancer.
BeijingAges 18–70 - NCT06962293Recruiting
Magnetic tool for removing early stomach or colon polyps
This trial uses a special magnetic device to help doctors remove early-stage growths in the stomach or colon during a standard procedure called endoscopic submucosal dissection (ESD). The magnet pulls the tissue into a better position, which may make the removal safer and more effective.
Hong KongAges 18–85 - NCT07128966Recruiting
Collect biospecimens and health data for research
This study collects blood, saliva, or other biospecimens and health information from people with certain medical conditions. Your samples and data will help researchers better understand diseases and develop new treatments.
Lexington, MassachusettsAges 18–90 - NCT07128797RecruitingPhase 1
Safety and tolerability of B1344 injections for NAFLD
This trial tests whether multiple injections of B1344 are safe and tolerable in people with nonalcoholic fatty liver disease (NAFLD). It aims to find the right dose and check how the drug works in the body.
Beijing, Beijing MunicipalityAges 18–75
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,606 recruiting gastroenterology studies from the U.S. registry right now, out of 12,023 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.