Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,874 recruiting studies in this area right now.
By phase
- Not applicable4,909
- Phase 21,178
- Phase 1584
- Phase 3466
- Phase 1/Phase 2389
- Phase 4235
- Phase 2/Phase 3113
Top conditions
- Colorectal Cancer495
- Gastric Cancer297
- Pancreatic Cancer294
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer174
- Breast Cancer146
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer113
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)103
- Liver Cancer99
- Lung Cancer98
- Pancreas Cancer94
- Ovarian Cancer90
- Esophageal Squamous Cell Carcinoma88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University89
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center59
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California465
- Arizona175
- Texas146
- Florida134
- Massachusetts128
- New York123
- Alabama121
- Maryland86
- Ohio78
- Pennsylvania72
Recruiting studies7,874 total
- NCT03135886Recruiting
Testing for HIV in opioid treatment programs
This project studies how to improve offering and completing HIV (and hepatitis C) tests in opioid treatment programs. It may help increase timely follow-up and linkage to care when results are positive.
New York, New YorkAges 18 years+ - NCT04674267Recruiting
REACH study for older adults with GI cancer and support needs
This study looks at how to improve health and care support for people age 70 and older with gastrointestinal (GI) cancer. It may help by offering a structured way to address practical and emotional challenges that can affect aging and cancer care.
Boston, MassachusettsAges 70 years+ - NCT06578936Recruiting
Massage and warmth after knee replacement
This study tests whether gentle belly massage and a warm pack help people have a bowel movement more quickly after total knee replacement surgery done under spinal anesthesia. It looks at how these simple, drug-free treatments may help get your bowels working again after surgery.
AdanaAges 18 years+ - NCT06459661Recruiting
Bowel movement tracking study for healthy adults
This study tracks bowel movements in healthy people to learn more about normal gut function. It involves attending an in-person session at a university in Leeds or Sheffield.
LeedsAges 18–60 - NCT06438809RecruitingPhase 1/Phase 2
Stem cell injection for chronic radiation proctitis
This study tests whether a single injection of special cells (umbilical cord stem cells) can help heal long-term inflammation in the rectum caused by previous pelvic radiation. It's for people whose standard treatments have not worked.
Nanjing, JiangsuAges 18–79 - NCT06433115Recruiting
Lean beef and your heart and gut health trial
This study tests how eating lean beef for 4 weeks affects your heart health and the bacteria in your gut. If you qualify, you'll be asked to follow a consistent diet and activity routine during the study.
Columbia, MissouriAges 18–45 - NCT06371924Recruiting
Machine perfusion for livers from donation after circulatory death
This study tests a new way to preserve donated livers (called machine perfusion) after they are recovered from donors who died from circulatory causes. It aims to see if this method helps the liver work better before transplant.
BirminghamAges 18 years+ - NCT06304337Recruiting
New airway device for painless endoscopy
This trial is testing a new device to help keep your airway open during painless upper and lower endoscopy. It may be helpful for people who are already healthy enough for routine sedation.
JinanAges 18–95 - NCT06257407Recruiting
Managing bleeding during and after liver transplant
This trial studies how doctors manage bleeding before, during, and after liver transplant surgery. The goal is to improve safety and outcomes for people receiving a new liver.
BesançonAges 18 years+ - NCT06246630Recruiting
Personalized drug testing for advanced pancreatic neuroendocrine tumors
This trial uses a lab-grown model of your tumor (called an organoid) to test which drugs might work best for you. It is for people with advanced pancreatic neuroendocrine tumors who cannot have surgery.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06228963RecruitingPhase 2
Orelabrutinib for H. pylori-positive gastric MALT lymphoma
This trial tests a targeted drug called orelabrutinib for people with a specific type of stomach lymphoma that is linked to an active H. pylori infection. The goal is to see if the drug can help shrink or control the lymphoma.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06193551Recruiting
Ovitex use in large hiatal hernia repair
This trial tests a product called Ovitex used during surgery to fix a large hiatal hernia (a condition where the stomach pushes up into the chest). If you are scheduled for this surgery, Ovitex may help improve the repair.
Lone Tree, ColoradoAges 18–85 - NCT06162767Recruiting
Surgery comparison for junction cancer
This trial compares two surgical techniques for treating a specific type of cancer at the junction of the stomach and esophagus. It aims to find which surgery offers better outcomes for patients.
Nanjing, JiangsuAges 18–80 - NCT06149689RecruitingPhase 2
Chemo plus radiation for advanced pancreatic cancer with normal CA19-9
This trial tests whether giving a strong chemotherapy combination (mFOLFIRINOX) together with radiation therapy can help people with advanced pancreatic cancer who have normal CA19-9 levels. It aims to see if this approach is more effective for this specific group of patients.
ShanghaiAges 18–80 - NCT06077435Recruiting
AI software for better polyp detection during colonoscopy
This study compares the use of artificial intelligence (AI) software to standard methods for finding and diagnosing polyps during a colonoscopy. It may help you get a more accurate exam.
Gothenburg, GothenbburgAges 50–90 - NCT05967871RecruitingPhase 1
Testing poop-based therapy for kids with SIBO
This early study tests whether fecal microbiota transplant (a stool donation placed into the gut) is safe and practical for children with small intestinal bacterial overgrowth (SIBO). It may help reduce SIBO symptoms, but the main goal is to see if the treatment and study steps work well.
Hamilton, OntarioAges 3–18 - NCT05967273Recruiting
Cirrhosis treatment support system for hospitalized adults
This trial studies a computer-based “CDS” system designed to support care decisions for people hospitalized with cirrhosis. It may help doctors deliver more consistent, safer treatment while you’re in the hospital.
San Francisco, CaliforniaAges 18 years+ - NCT05964439Recruiting
Testing augmented reality guidance for ultrasound procedures
This study tests whether an augmented reality (computer-generated overlay) app can help people perform ultrasound scans more easily and accurately. You may be eligible if you are trained/experienced with using ultrasound at the bedside and you have not used the specific HoloUS app version before.
Washington D.C., District of ColumbiaAges 18–100 - NCT05940857Recruiting
Liver transplant registry using a special machine before surgery
This is a registry that collects information about liver transplant recipients. It helps researchers understand outcomes related to a specific liver “perfusion” process used around the time of transplant.
Birmingham, AlabamaAges Any age - NCT05867134Recruiting
Activity limits after one-sided groin hernia surgery
This trial studies how restricting or allowing activities after surgery for a one-sided inguinal hernia affects recovery and outcomes. It may help determine the safest activity plan while you heal.
Aurora, ColoradoAges 18–99 - NCT05866796Recruiting
Test blood patterns to predict problems after liver transplant
This study checks whether a special blood test can predict who is at higher risk of graft loss (the transplanted liver not working well) and death after a liver transplant. It may help doctors identify higher-risk patients earlier and tailor follow-up care.
Ghent, FlandersAges 18 years+ - NCT05779436Recruiting
AI camera tool to examine bile duct narrowings during ERCP
This study tests an artificial-intelligence computer add-on (an AI “camera guide”) used during a procedure that looks inside the bile ducts. If you have a bile duct narrowing, it may help the doctor more quickly and accurately identify the cause while you undergo the usual procedure.
Worcester, MassachusettsAges 18 years+ - NCT05758961Recruiting
Study of gut bacteria in adults living in France
This study looks at the types of bacteria in your gut (gut microbiota) by analyzing a stool sample. It aims to better describe typical gut bacteria patterns in France and may help researchers understand links to health.
BobignyAges 18 years+ - NCT05528900Recruiting
Study of children with acute food-triggered gut reactions
This study follows children (from birth to age 17) who have been diagnosed with acute food protein–induced enterocolitis syndrome (FPIES). Doctors want to better understand this condition after a suspected reaction to food, using either symptom-based diagnosis or a supervised food challenge when needed.
AngersAges Up to 17 years
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,874 recruiting gastroenterology studies from the U.S. registry right now, out of 12,294 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.