Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT05705024RecruitingPhase 2
Eye drops/treatment to heal stubborn cornea surface damage
This Phase 2 trial tests a locally delivered cell-based treatment (allogeneic mesenchymal stromal cells) to help heal long-lasting damage to the eye’s clear surface (the cornea). It may help if your cornea epithelium (surface layer) won’t improve even after standard non-surgical treatments.
Chicago, IllinoisAges 18 years+ - NCT05705778Recruiting
Blood biomarker study in children with amblyopia
This trial looks at a blood test (a “biomarker”) in children with amblyopia, a common vision development problem. It may help researchers understand what changes go along with treatment and vision improvement.
Guangzhou, GuangdongAges 3–12 - NCT05710198RecruitingPhase 3
Citicoline eye drops to slow vision field loss in glaucoma
This Phase 3 trial tests whether citicoline 2% eye drops can help slow worsening of the visual field in adults with open-angle glaucoma. If you qualify, you would be monitored with repeated eye tests to see if your vision field stays more stable over time.
Milan, MIAges 18 years+ - NCT05716945RecruitingPhase 4
OPTIMISE Study for patients getting cornea transplant surgery
This trial looks at how to manage medicine around DMEK corneal transplant surgery to improve eye outcomes and safety. It may help people having this specific type of cornea transplant by testing an approach in the time after surgery.
Apeldoorn, GelderlandAges 21 years+ - NCT05724641Recruiting
MRI test of eye blood flow in specific optic nerve conditions
This study uses a special MRI scan to measure blood flow to the eye and check how consistently the results match over time. It may help doctors better assess certain optic nerve problems, especially in people without major cardiovascular risk factors.
Brussels, Brussels CapitalAges 18 years+ - NCT05727540Recruiting
Cohort study of people with uveitis
This study follows people who have been diagnosed with uveitis (inflammation inside the eye). It helps researchers better understand the condition and how people do over time.
Guangzhou, GuangdongAges 18–90 - NCT05733182Recruiting
Lamp color test to prevent nearsightedness in kids
This study tests whether the color of a reading lamp can help reduce how likely children are to become or worsen nearsightedness (myopia). Your child’s eyes may be followed over time to see if the lamp type affects eye measurements.
Hong Kong, KowloonAges 4–18 - NCT05733728Recruiting
Uveal melanoma medical record study
This study looks back at past medical records of people diagnosed with uveal melanoma. It helps researchers learn about the typical course of the disease by analyzing what already happened in care.
ViennaAges 18–99 - NCT05742321Recruiting
Study how corneal cell genetics relate to Fuchs’ disease
This study looks at how a person’s corneal cell genetic makeup relates to what happens in Fuchs’ corneal endothelial dystrophy. It may help doctors understand the disease better and guide future care, especially if you need a corneal transplant.
Saint-EtienneAges 18 years+ - NCT05746078Recruiting
Testing elastic threads to lift mild to moderate facial sagging
This trial tests the safety and performance of a special “elastic thread” treatment used to lift facial drooping (mild to moderate ptosis) in people who may or may not have had prior cosmetic treatments. You may benefit by getting the study treatment, but you would need to follow the visit schedule and rules of the study.
CréteilAges 35–75 - NCT05749094Recruiting
Ultrasound of the optic nerve in new suspected giant eye artery disease
This trial studies whether a quick ultrasound of the optic nerve (plus an eye exam) can help evaluate new suspected giant cell arteritis (GCA). It may help doctors assess eye risk early and decide on the best next steps.
London, OntarioAges 50–99 - NCT05752214Recruiting
Quality-of-life study for adults with vision problems
This study looks at how life quality changes or is measured in adults who have vision problems and are in specialized vision rehabilitation. You may be asked to answer questionnaires to help the research team understand your experience.
RomaAges 18 years+ - NCT05753137Recruiting
Acupuncture along with glaucoma drops for mild or moderate glaucoma
This trial studies whether adding acupuncture to your usual glaucoma medication can help with glaucoma control in people with mild or moderate primary open-angle glaucoma. It compares acupuncture plus treatment versus treatment alone (randomly assigned).
TaichungAges 20 years+ - NCT05756959Recruiting
Tested light-based treatment plus special lenses for childhood myopia
This study tests whether combining PBM (a light/laser treatment used in eye studies) with a special myopia-defocus lens can slow nearsightedness in children. It may help reduce how fast eyesight gets worse over time.
Xuzhou, JiangsuAges 6–13 - NCT05759780Recruiting
Check how an eye probe measures tissue softness
This study uses a special eye/skin/gum imaging test to measure how tissues behave. It may help researchers improve noninvasive ways to understand eye and tissue health, and in some parts of the study, mild keratoconus.
Boston, MassachusettsAges 18–75 - NCT05765162Recruiting
Research study on safer, more tailored anesthesia
This study looks at safer anesthesia—meaning medicines used during procedures—using a more personalized approach. It may help make anesthesia safer for adults having medical procedures.
Nykøbing FalsterAges 18–100 - NCT05767047RecruitingPhase 3
Apremilast study for children with mouth ulcers from Behçet’s
This trial studies whether apremilast can help reduce mouth ulcers in children who have Behçet’s disease or juvenile psoriatic arthritis. You may be considered if your child finished a main study and is under 18, and can safely continue treatment.
ThessalonikiAges 5–18 - NCT05786196Recruiting
Testing canaloplasty surgery for mild to moderate glaucoma
This study tests how well a specific glaucoma surgery (canaloplasty) works on its own for people with mild to moderate primary open-angle glaucoma. It may help if drops (eye medicines) do not work well for you or you need fewer eye drops.
DüsseldorfAges 22 years+ - NCT05801471Recruiting
Tracking vision field changes in glaucoma patients
This study looks at different ways to measure how glaucoma affects your vision over time by comparing visual field results. It may help researchers find better models to track progression so treatment decisions can be made more accurately.
Milan, MilanoAges 40–90 - NCT05803785RecruitingPhase 1
Safety study of an injection for wet macular degeneration
This Phase 1 trial tests whether BBC1501, an injection given into the eye, is safe for people with wet age-related macular degeneration (nAMD). It mainly looks at side effects and whether the study injections can be given safely in patients who still have active disease despite prior anti-VEGF treatments.
Sydney, New South WalesAges 50 years+ - NCT05809635Recruiting
Study for BEST1-related macular eye disease
This trial is studying people with BEST1-associated vitelliform macular dystrophy, a genetic eye condition affecting central vision. It will involve several eye-related study visits over about three years, aiming to better understand the condition and how it is managed.
New York, New YorkAges Any age - NCT05814952Recruiting
LX103 eye treatment for X-linked retinoschisis
This trial studies whether LX103 can improve vision and is safe for people with X-linked retinoschisis (XLRS) caused by RS1 gene changes. It focuses on a specific level of vision in the study eye and checks for medical conditions that could affect eye testing or safety.
ShanghaiAges 6 years+ - NCT05832723Recruiting
Red light eye therapy for children with mild focusing error
This study tests whether low-intensity red light at 650 nm can help children and teens with mild problems focusing their eyes. It is designed to see if the treatment is safe and useful for the right type of refractive error.
Beijing, Beijing MunicipalityAges 7–18 - NCT05844384Recruiting
Testing a new eye drop bottle for glaucoma
This study checks whether a device called the Nanodropper helps deliver glaucoma medicine as well as standard use. It is for adults with stable primary open-angle glaucoma (or ocular hypertension) who are on a limited number of eye-pressure medicines.
Lackland Air Force Base, TexasAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.