Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07321769Recruiting
3D eye modeling study for lens and eye structure disorders
This trial uses advanced imaging to create 3D models of the eye in people with lens problems, eye structure anomalies, trauma, or cataract complications. It aims to improve diagnosis and treatment planning for these conditions.
Hangzhou, ZhejiangAges Any age - NCT07323251Recruiting
Do special glasses slow down myopia in children?
This study tests whether new spectacle lenses (glasses) can slow down the progression of nearsightedness (myopia) in children. It may be a good option if your child's myopia is getting worse and you want to try a non-invasive approach.
BeijingAges 6–14 - NCT07322965Recruiting
Citicoline and DHA supplement for glaucoma patients
This trial tests whether a dietary supplement (DHA + citicoline) can help protect vision in people with glaucoma. You may qualify if you have confirmed glaucoma in at least one eye and are between 50 and 75 years old.
Barcelona, BarcelonaAges 50–75 - NCT07321756Recruiting
Presbyopia-correcting lens implants for complex cataracts
This study tests special lenses (IOLs) that aim to correct presbyopia (trouble seeing up close) in people with complex cataracts or other eye conditions. It may help if you have a lens that is partially out of place, long-term eye inflammation, a cataract after laser eye surgery, or if you are missing a lens and need a new one.
Hangzhou, ZhejiangAges 18–80 - NCT07322302Recruiting
Comparing two approaches for repeat eyelash surgery
This study compares two ways of doing repeat surgery for trichiasis (eyelashes turning inward) on the upper eyelid. The surgeries will be done by specially trained eye care workers, and the goal is to see which approach works better.
Chapel Hill, North CarolinaAges 18 years+ - NCT04847635Recruiting
Laser test for aging-related macular spots under the retina
This trial studies a mild (“subthreshold”) laser treatment for reticular pseudodrusen (RPD) caused by age-related macular degeneration (AMD). If you qualify, the goal is to see whether the laser helps preserve or improve vision by targeting these specific eye changes.
GenovaAges 55 years+ - NCT05927688Recruiting
Using patient reports to adjust treatment for autoimmune diseases
This study looks at whether doctors consider patient “electronic reports” (completed online/phone) when deciding how often to change treatment. It may help improve how well treatment plans match how patients feel over time.
StrasbourgAges 18 years+ - NCT07307469Enrolling by invitation
Extended access to ZVS101e for BCD patients
This trial offers compassionate use of the gene therapy ZVS101e for people with Bietti crystalline dystrophy (BCD) who were in the control group of an earlier study. It aims to give extended treatment access to those who didn't receive the experimental therapy before.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07308639Recruiting
Eye disease health data study in Germany
This study looks at health records in Germany to understand how many people have certain eye conditions like age-related macular degeneration, diabetic macular edema, or retinal vein occlusion. It also tests new ways to use this information for research.
LeverkusenAges 18 years+ - NCT07313618RecruitingEarly Phase 1
Gene therapy for children with oculocutaneous albinism type 1
This trial tests a single injection of JWK010 gene therapy for children aged 5 to 12 with OCA1A albinism. The therapy is given into the eye to try to improve vision, and is meant for those who have not had gene therapy before.
Chengdu, SichuanAges 5–12 - NCT07312214Recruiting
Red light therapy for slowing vision loss in severe nearsightedness
This trial tests if daily low-level red light can protect the back of the eye in people with severe nearsightedness. It aims to slow damage that leads to vision loss.
ShanghaiAges 18–55 - NCT07310719Recruiting
Comparing laser versus eye drops for new glaucoma patients
This trial compares two first treatments—laser therapy (SLT) or daily eye drops (latanoprost)—to lower eye pressure in people newly diagnosed with open-angle glaucoma or high eye pressure. It aims to find which approach works better as an initial therapy.
Ikeja, LagosAges 18–90 - NCT07305818RecruitingPhase 1
Testing a new drug for Graves' disease
This study tests a new medication called MER511 for adults with Graves' disease. The goal is to see if it is safe and how it works when taken once or multiple times.
Torrance, CaliforniaAges 18–65 - NCT07305987RecruitingPhase 3
Eye drop study for people after cataract surgery
This study tests a new anti-inflammatory eye drop (PRO-232) in people who had routine cataract surgery on one eye the day before. The goal is to see if it helps control swelling and pain without problems.
Tijuana, Estado de Baja CaliforniaAges 18 years+ - NCT07303296RecruitingPhase 2
Gene therapy study for vision loss from LHON
This trial tests a gene therapy called GS010 given as an injection into the eye for people with vision loss from LHON. It aims to see if it can help improve vision in both eyes.
ParisAges 15 years+ - NCT06844292Recruiting
Comparing two microglaucoma surgeries with cataract surgery
This study compares two different devices (MINIject® and Hydrus® Microstent) used in microinvasive glaucoma surgery, both done at the same time as cataract surgery. It aims to find which one works better at lowering eye pressure.
Graz, StyriaAges 18 years+ - NCT07303257Recruiting
Quality of life after glaucoma surgery: a patient-centered study
This study compares how different types of glaucoma surgery affect your daily life and well-being. If you need glaucoma surgery, you may join to help doctors understand which procedure works best from a patient's perspective.
LyonAges 18 years+ - NCT07297849Recruiting
Eyelid closure effect on cornea measurement
This trial tests whether closing the eyelids changes the accuracy of a cornea measurement tool. It may help people whose cornea measurements are flagged as "warning" by the device.
Vienna, State of ViennaAges 18 years+ - NCT07303920Recruiting
Comfort of daily disposable contacts for astigmatism over a long day
This study tests how comfortable daily disposable contact lenses for astigmatism feel when worn for a long day (like 16 hours). It may help you find a lens that stays comfortable and clear from morning to night.
Columbus, OhioAges 18–40 - NCT07298356Recruiting
Updated eye pressure measurement in routine exams
This study tests an updated device that measures eye pressure during a routine eye exam. It is for adults who are already coming in for a check-up and have no eye infections or scarring.
Durham, North CarolinaAges 18 years+ - NCT07301892Recruiting
AI help for rheumatoid arthritis diagnosis
This trial tests whether artificial intelligence (AI) can improve how doctors spot complications in people newly diagnosed with rheumatoid arthritis (RA), a condition that causes joint pain and swelling. The goal is to see if AI can make diagnosis faster and more accurate in real-world hospital settings.
Beijing, Beijing MunicipalityAges Any age - NCT07301164RecruitingEarly Phase 1
BCT301 cell therapy for hard-to-treat autoimmune diseases
This trial tests a new cell treatment called BCT301 for people with certain autoimmune diseases like lupus or scleroderma that haven't gotten better with standard medicines. It aims to see if this treatment can help control the disease.
BeijingAges 18–80 - NCT06031727RecruitingEarly Phase 1
CRISPR gene therapy for wet age-related macular degeneration
This trial tests a new CRISPR-based treatment for wet age-related macular degeneration (AMD). It aims to stop vision loss by targeting the cause of abnormal blood vessel growth in the eye. This study is for people who have already tried anti-VEGF injections but might not be responding well enough.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT06879782RecruitingPhase 3
Eye drops for dry eye disease: a phase 3 study
This study tests an eye drop called lifitegrast for people with dry eye disease. It looks at whether the drops can improve eye comfort, reduce dryness, and help eye surface health. You may be able to join if you have had dry eye symptoms and used artificial tears in the past month.
Beijing, Beijing MunicipalityAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.