Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07337317Recruiting
Testing stairway designs for people with vision loss
This study compares different stairway designs to see which are easier and safer for people with vision impairment. It will help identify features that make stairs more accessible.
Huntsville, AlabamaAges 65 years+ - NCT06607705Recruiting
Eye pressure changes after iStent surgery with a contact lens sensor
This study tests a tiny implant (iStent inject W) that helps lower eye pressure in people with open-angle glaucoma. A special contact lens sensor will monitor your eye pressure after surgery. The goal is to see how well the implant works and how it changes your eye pressure throughout the day.
Barcelona, SpainAges 18 years+ - NCT06865274Recruiting
A look at gene changes in MS, NMOSD, and MOGAD
This study looks at a specific gene change in people with MS, NMOSD, or MOGAD to see how common it is. By joining, you help researchers learn more about these conditions and possible future treatments.
Roma, RomaAges 18 years+ - NCT07329712Recruiting
Light therapy for dry eye: tear protein study
This trial tests whether low-level light therapy can improve dry eye disease by measuring changes in tear proteins. It may help people with chronic dry eye who are interested in a non-drug treatment.
SingaporeAges 21 years+ - NCT07325162Recruiting
New eye scanner for cataract patients
This study is testing a new optical device that measures the eye before cataract surgery. It may help doctors get more accurate measurements for your lens implant.
Hilton Head Island, South CarolinaAges 18 years+ - NCT07325097RecruitingPhase 1
Corneal implant for swelling of the cornea
This trial tests a new corneal implant to treat corneal swelling caused by Fuchs' dystrophy or after cataract surgery. It aims to improve vision and reduce the need for a full corneal transplant.
YerevanAges 18 years+ - NCT07330674RecruitingPhase 1
Safety study of ABF-101 in healthy people and AMD patients
This trial tests the safety of a new drug called ABF-101 in two groups: healthy volunteers (Part A and B) and people with age-related macular degeneration (AMD, Part C). If you join, you will help researchers understand how the drug affects the body and if it's safe enough to study further.
Dallas, TexasAges 18–50 - NCT07329777RecruitingPhase 3
Atropine eye drops for children with worsening nearsightedness
This trial tests whether daily atropine eye drops can slow down worsening nearsightedness in children. It's for kids aged 5–10 whose myopia is actively progressing.
Kuala Lumpur, CherasAges 5–10 - NCT06865235Recruiting
Glaucoma and cataract surgery with a new device
This trial tests a surgery that combines cataract removal with a new technique to lower eye pressure in people who have both primary open-angle glaucoma and cataracts. It aims to see if this combined surgery is safe and effective.
Belo Horizonte, Minas GeraisAges 40 years+ - NCT07325188Recruiting
Smart Guide for Toric Lens Positioning in Cataract Surgery
This trial tests a new guidance system to help doctors place toric lenses more accurately during cataract surgery. It may help people who need a toric lens to correct astigmatism.
Gainesville, GeorgiaAges 18 years+ - NCT07325552Recruiting
Comparing two glaucoma surgeries with cataract surgery
This trial tests which of two micro-surgeries for glaucoma works better when you're also having cataract surgery. It may help you if you have both cataracts and glaucoma and take eye drops to control eye pressure.
Bialystok, PolskaAges 4 months+ - NCT07333677RecruitingEarly Phase 1
Testing CAR-T therapy for severe graves' disease
This early-phase trial tests a new type of treatment called CAR-T cells (special immune cells made in a lab) to target and calm down the overactive immune system in people with severe Graves' disease that hasn't improved with standard medicines. It may offer a new option for those who have been on treatment for years or have had multiple relapses.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07327242Enrolling by invitation
AI tool to improve eye test accuracy in glaucoma patients
This trial tests if a large language model tool can help patients perform more reliable visual field tests. It may improve detection of glaucoma progression.
Palo Alto, CaliforniaAges 18 years+ - NCT07332988Enrolling by invitation
Light therapy for dry eyes in Graves' disease
This trial tests if low-level light therapy can improve dry eye symptoms in people with Graves' disease whose dry eyes haven't gotten better with standard treatments like artificial tears.
Iași, IaşiAges 18 years+ - NCT07325240RecruitingPhase 4
Comparing Rocklatan and Latanoprost for eye pressure
This study compares a new combination eye drop (Rocklatan) to a standard one (Latanoprost) to see how well they control eye pressure over 24 hours. It may help people with open-angle glaucoma or high eye pressure find a more effective treatment.
Rochester, MinnesotaAges 18 years+ - NCT07329686RecruitingPhase 1/Phase 2
Anti-VEGF Injection for Herpes-Related Corneal Blood Vessels
This study tests whether injecting an anti-VEGF medication directly into the clear part of your eye (cornea) can safely reduce abnormal blood vessels caused by a herpes virus eye infection. If you have HSV keratitis with new vessel growth and haven't had prior anti-VEGF treatment or corneal surgery, this trial may be an option for you.
Hangzhou, ZhejiangAges 18 years+ - NCT06841471Recruiting
Role of Corneal Nerves in Dry Eye Disease
This study looks at how the nerves in the front of the eye (corneal nerves) relate to dry eye disease. It compares people with dry eye to those without to understand differences.
OltenAges 18 years+ - NCT07316998Recruiting
Myopia study for healthy young children
This study follows children with normal vision to see who develops nearsightedness (myopia) and what factors might affect it. It aims to understand how eye development and environment together influence the need for glasses.
ParisAges 4–8 - NCT07323264Recruiting
Creating a dry eye test for cataract patients
This research study aims to develop better ways to diagnose and manage dry eye disease in people who need cataract surgery. If you have dry eye or not, your participation will help create better care plans.
SingaporeAges 21–99 - NCT07323953Recruiting
AmblyoFix study for children with lazy eye
This trial tests a new treatment called AmblyoFix for children aged 7 to 12 with lazy eye (amblyopia) in one eye. The study aims to see if it helps improve vision better than standard care.
CairoAges 7–12 - NCT07317934RecruitingPhase 3
Gene therapy for wet age-related macular degeneration
This study tests a one-time gene therapy called LX102 for wet age-related macular degeneration (AMD). It may reduce the need for frequent eye injections and help preserve vision.
Hefei, AnhuiAges 50–80 - NCT07322211Recruiting
Testing a new daily disposable contact lens
This trial tests a new daily disposable silicone hydrogel contact lens for people with moderate nearsightedness. It will check if the lens is safe, comfortable, and gives good vision.
Kaohsiung CityAges 3 weeks+ - NCT07318961Recruiting
Using a piece of your own eye tissue to fix a stubborn macular hole
This trial tests whether a small piece of tissue from your own eye (the Tenon's capsule) can be used as a patch to help close a macular hole that hasn't healed with previous surgery or is chronic and large.
Banhā, BenhaAges 18 years+ - NCT07322302Recruiting
Comparing two approaches for repeat eyelash surgery
This study compares two ways of doing repeat surgery for trichiasis (eyelashes turning inward) on the upper eyelid. The surgeries will be done by specially trained eye care workers, and the goal is to see which approach works better.
Chapel Hill, North CarolinaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.