Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT05589714Recruiting
Study your rare eye gene and track retinal disease over time
This study builds a registry and tracks the natural history of rare retinal dystrophies while also testing people for disease-causing gene variants. It may help researchers better understand what causes retinal degeneration and how it progresses.
Little Rock, ArkansasAges 4 years+ - NCT05589974Recruiting
Blood flow study in acute or chronic central serous eye disease
This study measures blood flow in the eye in people with acute or chronic central serous chorioretinopathy (CSC). It uses eye scans and special imaging to better understand what’s happening and whether it may differ between short-term and long-term disease.
StavangerAges 18–70 - NCT05590416Recruiting
Adalimumab for early Vogt-Koyanagi-Harada eye inflammation
This trial studies adalimumab to treat a rare, fast-onset eye inflammation called Vogt-Koyanagi-Harada disease. It may help people who can’t use strong steroid treatments or whose disease is not improving quickly with them.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT05592717Recruiting
YUTIQ implant for chronic non-infectious eye inflammation
This trial tests whether a small steroid implant placed inside the eye (YUTIQ 0.18 mg) can control chronic non-infectious uveitis. It may help reduce active inflammation and prevent flare-ups, as long as you’ve had recent signs of active disease and can follow the medication and eye-visit rules.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT05600140Recruiting
Training kids to look smarter with visual impairment
This trial studies whether a “viewing strategy” training program can improve how children with visual impairment use their vision for learning and daily tasks. It looks at whether the training helps most when kids still struggle with visual processing.
NijmegenAges 5–12 - NCT05605314Recruiting
Study different types of dry eye in Sjögren’s
This study looks at patients with Sjögren’s-related dry eye to understand how different subtypes affect tear function and eye symptoms. It may help doctors better sort out dry eye types, which can guide more tailored care.
BeijingAges 18–80 - NCT05606237Recruiting
Red-light sessions to slow worsening nearsightedness
This study tests whether repeated low-level red-light therapy can slow how fast nearsightedness (myopia) gets worse in children. It may help protect future eyesight, but your child must meet specific vision and health requirements and follow the study plan.
San Francisco, CaliforniaAges 8–13 - NCT05613608RecruitingPhase 2/Phase 3
Cannabidiol (CBD) study for alcohol use disorder
This trial tests whether cannabidiol (CBD) can help people cut down or quit drinking alcohol. It enrolls adults diagnosed with alcohol use disorder and wanting to reduce drinking, while checking for safety and other mental health or drug use factors.
Aurora, ColoradoAges 21 years+ - NCT05616793RecruitingPhase 1/Phase 2
Gene therapy eye surgery for LCA5 vision loss
This Phase 1/2 study tests the safety of putting a gene medicine into the eye for people with vision loss caused by LCA5 gene mutations. It includes a treatment group and a separate group of people who do not receive the gene medicine during the study.
Philadelphia, PennsylvaniaAges 4 years+ - NCT05624398Recruiting
Hydrus stent plus cataract surgery for mild glaucoma
This study looks at outcomes for people with mild glaucoma who need cataract surgery, comparing how well the Hydrus stent works when placed during cataract surgery. The goal is to see whether this combined approach keeps eye pressure and vision stable with fewer issues.
Fayetteville, ArkansasAges 45 years+ - NCT05626114RecruitingPhase 2
Study of a lab-made eye treatment after subretinal surgery
This Phase 2 study tests OpRegen, a treatment delivered during special eye surgery, for geographic atrophy related to age-related macular degeneration (GA from AMD). It also includes an imaging “substudy” that uses detailed pictures of your retina to better track safety and activity.
Beverly Hills, CaliforniaAges 50 years+ - NCT05626426Recruiting
Electrical stimulation for optic nerve damage from glaucoma
This trial studies whether electrical stimulation can help improve vision in people with glaucoma-related optic nerve damage. You may qualify if your visual field test shows moderate to severe loss and your eye pressure is stable.
Palo Alto, CaliforniaAges 18 years+ - NCT05632887Recruiting
Testing how eyeliner changes eye tears
This study compares how eyeliner affects your tears—like tear makeup, how much your eyes produce, and how long the tear layer stays stable. You might help researchers understand whether eyeliner use impacts eye comfort or dryness.
Wuhan, HubeiAges 20–35 - NCT05636579RecruitingPhase 1
Testing safety of multiple EO2002 eye drops for corneal swelling
This Phase 1 study tests whether EO2002 eye drops are safe and well tolerated in people with painful corneal swelling caused by the cornea’s inner lining not working well. It focuses on safety first, but your eye symptoms and vision may be monitored to see how you respond.
Mexico City, Mexico CityAges 18 years+ - NCT05654025Recruiting
Study of eyesight outcomes after congenital lens dislocation
This follow-up study looks at how vision changes over time in children and adults with congenital lens dislocation, and what complications may occur. It may help doctors better predict outcomes and prevent problems after diagnosis.
Guangzhou, GuangdongAges 3 years+ - NCT05663684RecruitingPhase 4
Topical numbing drops to reduce pain during tear duct testing
This Phase 4 trial studies whether numbing eye drops (proparacaine 0.5%) can reduce pain during a procedure called probing and irrigation of the tear drainage system. If you need this test for ongoing watery eyes, the trial may help make the procedure more comfortable.
New Orleans, LouisianaAges 18 years+ - NCT05667454RecruitingPhase 3
Test atropine eye drops to slow worsening nearsightedness in kids
This Phase 3 trial tests different doses of atropine eye drops to see which dose best slows myopia (nearsightedness) from getting worse in children. It may help by reducing how fast your child’s eyesight changes over time.
Almere StadAges 6–11 - NCT05672121RecruitingPhase 1/Phase 2
Gene therapy safety study for neovascular macular degeneration
This trial tests a new gene therapy drug (KH631) to see if it is safe and tolerated in people with neovascular age-related macular degeneration (nAMD). It may help your retina problems, but the early goal is mainly to learn about side effects and how the treatment behaves in the eye.
BeijingAges 50–85 - NCT05675150Recruiting
Art-based program for adults with age-related vision loss
This trial tests whether an expressive arts-based program can help adults who have age-related macular degeneration (a common cause of vision loss) by supporting wellbeing and daily functioning. If you meet the language, vision, and health requirements, participating may help you benefit from a structured arts intervention.
Hong KongAges 50–80 - NCT05676580Recruiting
Study of risk factors and vision changes in keratoconus
This study looks at what leads to keratoconus and how it progresses over time. It may help doctors better predict worsening vision and plan earlier care.
Montpellier, OccitanieAges 10–40 - NCT05678374Recruiting
Looking for immune signs linked to mental fatigue in Graves’ disease
This study looks at blood “immune” markers to understand why some people with Graves’ disease develop mental fatigue (feeling slowed down in thinking). It may help doctors better recognize and explain mental fatigue in Graves’ disease.
GothenburgAges 18–72 - NCT05694858RecruitingPhase 1/Phase 2
Numbing patch comparison before blood draw for eye care
This trial tests a numbing skin patch made with tiny microneedles against a standard numbing cream/patch to reduce pain before a blood draw. It may help you feel less discomfort during venepuncture before an eye procedure.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT05696561Recruiting
Testing a glaucoma procedure called canaloplasty device
This trial studies whether a canaloplasty device is safe and effective for people with open-angle glaucoma who are planning cataract surgery. It may help lower eye pressure when using eye drops is being reduced or stopped.
SantiagoAges 22 years+ - NCT05699096Recruiting
Drug aims to help detached retina and move fluid forward
This trial tests a medication intended to help fix a detached retina and shift the fluid underneath it. You may be considered if you’re an adult with keratoconus and no other active eye conditions.
Cairo, Kubri EL KubbaAges 20–50
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.