Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT05845723RecruitingPhase 2
Study drugs for blood-vessel Behçet’s to reduce inflammation
This Phase 2 trial tests tocilizumab and tofacitinib to see if they can better control vascular (blood-vessel) Behçet’s syndrome. It may help by lowering inflammation and reducing complications from aneurysms in the aorta or peripheral arteries.
Beijing, Beijing MunicipalityAges 18–65 - NCT05847387Recruiting
Checking endothelial cell health before corneal transplant
This study tests how well a patient’s corneal lining cells are preserved before corneal transplantation, and uses that to guide the transplant approach. It may help improve transplant planning and outcomes for people who need treatment for conditions like keratoconus or Fuchs endothelial dystrophy.
EdegemAges 18 years+ - NCT05851287Recruiting
Eye and health check study for adults 65 and older
This study enrolls people age 65+ to get regular eye and general health checkups. It may help doctors understand what eye problems are developing and how to catch them earlier.
Guangzhou, GuangdongAges 65 years+ - NCT05853107Recruiting
AuTNA I implant study for retinitis pigmentosa with minimal vision
This pilot study tests an implant called AuTNA I in adults with retinitis pigmentosa who currently have no or only very limited light perception. The goal is to see whether the implant can work safely and potentially improve vision in a carefully selected group of people.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05863312Recruiting
Study of outcomes after retinal detachment repair
This study looks at how well surgery works for people with a specific type of detached retina (rhegmatogenous retinal detachment). It may help improve how doctors choose and manage treatment, based on what outcomes happen after repair.
Québec, QuebecAges 18 years+ - NCT05865093Recruiting
Check early vision changes in infants at risk for brain vision problems
This pilot study looks at early vision (what babies can see and how their eyes respond) in children who have risk factors for future “cerebral visual impairment,” meaning vision problems caused by the brain. It may help doctors spot issues earlier and better understand which early visual signs matter.
RomeAges 2 days–3 years - NCT05865457Recruiting
Testing two eye treatments for dry eye symptoms
This trial compares two different dry-eye eye drops to see which works better and is safe. You may be able to join if you’ve had dry eye for at least 3 months and meet specific eye-test results.
GrazAges 18 years+ - NCT05870566Recruiting
Vitamin and light treatment before risky corneal transplant
This trial studies whether pretreatment with a specific vitamin and ultraviolet light can help a future, high-risk corneal transplant keep its new cornea healthy for longer. It may help people whose corneas already have new blood vessels, which can make transplant results harder.
München, BavariaAges 18 years+ - NCT05874258Recruiting
Electric brain stimulation plus vision training for glaucoma
This trial tests whether combining a short vision learning program with non-invasive electrical stimulation to the brain can improve vision in people with open-angle or normal-tension glaucoma. It may help by training the visual system while stimulating brain pathways to support vision.
Hong KongAges 18–80 - NCT05877560Recruiting
Noninvasive brain stimulation for eye focusing trouble
This study tests a noninvasive brain stimulation treatment to improve symptoms of convergence insufficiency, a condition that makes near vision tasks like reading harder. You may be randomly assigned to the study treatment or a comparison condition.
Downers Grove, IllinoisAges 18–40 - NCT05883072Recruiting
Using AI to support care for people with diabetes in Pakistan
This study tests whether AI-generated support can be helpful for adults living with diabetes. You may be asked to participate if you live in Pakistan and can legally consent.
Karachi, SindhAges 18–100 - NCT05885022Recruiting
Testing a glaucoma device during eye surgery planning
This study checks whether the Calibreye System can be used safely and effectively for people with certain types of glaucoma. It may help doctors better assess the eye before treatment, especially for selecting the right surgical approach.
ChennaiAges 18 years+ - NCT05888441Recruiting
Walking obstacle testing in people with and without vision trouble
This trial studies how people negotiate obstacles while walking, comparing those with normal vision and those with vision impairment. It may help researchers better understand balance and safety needs for walking in everyday settings.
Bloomington, IndianaAges 18 years+ - NCT05891379Recruiting
Inebilizumab for adults with acute neuromyelitis optica attacks
This trial studies inebilizumab to treat adults with neuromyelitis optica spectrum disorder (NMOSD) who are having an acute attack. It aims to reduce ongoing nerve damage and disability after a recent flare, alongside standard steroid treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05904301Recruiting
Registry for autoimmune and autoinflammatory disease patients
This study builds a nationwide list (registry) of people with certain autoimmune or inflammation-related illnesses. It helps researchers understand these diseases better over time, which can guide future care.
YerevanAges Any age - NCT05906953RecruitingPhase 1/Phase 2
HG004 gene therapy for RPE65 vision loss
This Phase 1/2 trial tests the safety and early effectiveness of HG004 (a gene therapy) in people with Leber congenital amaurosis caused by RPE65 gene changes. It aims to see whether treating the eye can improve or stabilize vision-related measures while monitoring side effects.
Sacramento, CaliforniaAges 6–50 - NCT05911503RecruitingEarly Phase 1
High-dose ganciclovir eye drops for CMV eye infection
This early-phase study tests high-concentration ganciclovir eye drops to treat cytomegalovirus (CMV) retinitis, a serious eye infection. It may help people who are hard to treat with regular (systemic) antiviral medicine or who face higher risks with an injection directly into the eye.
Tianjin, Tianjin MunicipalityAges 2–80 - NCT05913063Recruiting
Testing how the eye responds to tiny quantum states
This study looks at how the human eye detects very small “quantum” information. It compares people with certain vision conditions to people with normal vision to see how the eye’s macula and overall vision are involved.
Hong Kong, GuangdongAges 18 years+ - NCT05924477Recruiting
Compare glaucoma shunt options to prevent cell loss
This study compares a glaucoma drainage device approach to see which one better prevents loss of corneal cells after surgery. You may benefit by receiving close monitoring around the time of glaucoma surgery and helping doctors improve surgical choices.
San Francisco, CaliforniaAges 18 years+ - NCT05927688Recruiting
Using patient reports to adjust treatment for autoimmune diseases
This study looks at whether doctors consider patient “electronic reports” (completed online/phone) when deciding how often to change treatment. It may help improve how well treatment plans match how patients feel over time.
StrasbourgAges 18 years+ - NCT05932069Recruiting
Exercise program for intermediate age-related eye disease
This study tests whether an active (aerobic) exercise program can improve day-to-day function in Veterans with intermediate age-related macular degeneration (AMD). To join, you must have the right type stage of AMD, be able to do the assessments and exercise, and meet health and internet needs.
Decatur, GeorgiaAges 65–89 - NCT05941182Recruiting
Remote eye follow-up using Vision self-testing
This trial looks at a real-world way to run remote (video/online) eye clinic follow-up visits that include self-testing. It may help your care be more convenient while still supporting proper eye checks from home.
Cambridge, CambridgeshireAges 4 years+ - NCT05954403Recruiting
Eye birth defect study from newborns to adults
This is a national study that follows people with certain rare eye birth defects and their families, including pregnant people. It aims to better understand how often related health issues happen and to study inheritance (DNA) in families.
Paris, Île-de-France RegionAges Any age - NCT05954416Recruiting
Study follow-up for rare skin and related genetic conditions
This study (a “cohort”) follows people with certain rare skin conditions over time. It helps doctors better understand these diseases and improve long-term care, and you may be asked to complete surveys.
BobignyAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.