Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07218783RecruitingPhase 3
Testing a new glaucoma implant with cataract surgery
This trial tests a new implant that releases medicine for glaucoma while you have cataract surgery. It may help lower eye pressure without using daily drops.
Houston, TexasAges 22 years+ - NCT07220408RecruitingPhase 2
TL-925 eye drops for seasonal eye allergies
This trial tests an investigational eye drop called TL-925 for people with seasonal allergic conjunctivitis (eye allergies triggered by pollen, grass, etc.). It aims to see if TL-925 can relieve symptoms like redness and itching.
Smyrna, TennesseeAges 18 years+ - NCT07220876Recruiting
VisiPlate implant for hard-to-control open-angle glaucoma
This trial tests a new device called VisiPlate that is placed in the eye to help lower pressure for people with hard-to-control open-angle glaucoma. It may be an option if standard treatments haven't worked well enough.
Glendale, ArizonaAges 45 years+ - NCT07215234RecruitingPhase 1/Phase 2
Study of an injection for geographic atrophy in AMD
This study tests a single injection of an experimental drug (SAR446597) into the eye for people with geographic atrophy, a late-stage form of dry age-related macular degeneration. The goal is to see if it can safely slow vision loss.
Peoria, ArizonaAges 60 years+ - NCT07215390RecruitingPhase 2
Study of APL-3007 plus Syfovre for geographic atrophy
This trial tests whether a new drug called APL-3007, when added to your current Syfovre treatment, can slow the progression of geographic atrophy (an advanced form of dry age-related macular degeneration). It's for people who have already been on Syfovre for at least 6 months.
Gilbert, ArizonaAges 60 years+ - NCT07218796RecruitingPhase 3
Bimatoprost implant with IOL vs. timolol drops for glaucoma
This trial tests if a bimatoprost implant placed during cataract surgery (combined with a special lens) can lower eye pressure better than standard timolol eye drops. It may help people with mild to moderate glaucoma or high eye pressure who are already planning cataract surgery.
San Antonio, TexasAges 22 years+ - NCT07217249Enrolling by invitation
Donor diabetes and cornea transplant success at 5 years
This study looks at how a donor's diabetes might affect the long-term success of a specific type of cornea transplant called DMEK. Participants from an earlier study (DEKS) will be followed for up to 5 years to see how well the transplant is doing.
Atlanta, GeorgiaAges 30–93 - NCT07213167Recruiting
Low contrast vision test for different lens implants
This trial checks how well you see in low light and low contrast after having cataract surgery with specific lens implants. It helps doctors understand which lenses work best in dim conditions.
Bakersfield, CaliforniaAges 22 years+ - NCT07217678RecruitingPhase 4
Eye drops and surface damage in glaucoma treatment
This study looks at how certain glaucoma eye drops affect the surface of your eye. It tests a new implant that may reduce damage and improve comfort.
Miami, FloridaAges 18 years+ - NCT07217665Enrolling by invitationPhase 2
AADvac1 vaccine for progressive supranuclear palsy
This trial tests a vaccine called AADvac1 for people with progressive supranuclear palsy (PSP), a brain condition that affects movement and thinking. The study wants to see if the vaccine can slow the disease down.
San Francisco, CaliforniaAges 41–86 - NCT04706234Recruiting
Check swallowing and voice function in neurodegenerative diseases
This study looks at how well the throat and voice-related functions work in people with certain long-term brain or nerve conditions. It uses a specific throat exam during FEES to better understand swallowing and laryngopharyngeal (throat-area) function.
Innsbruck, TyrolAges 18 years+ - NCT06780293RecruitingPhase 2
Laser acupuncture for dry eye and Sjogren's dry eye
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
Taipei, TaiwanAges 20–75 - NCT05566769Recruiting
Test a phone tool for self-checks in NMOSD
This study tests a digital (phone) tool that helps people with NMOSD do unsupervised self-assessments between clinic visits. It looks at how well the tool works and whether it is safe and understandable for patients.
Los Angeles, CaliforniaAges 18 years+ - NCT06498206Recruiting
Augmented reality training vs patching for lazy eye
This study compares using a special augmented reality (AR) headset versus wearing a classic eye patch to treat lazy eye (amblyopia). It is for people ages 5–55 whose weaker eye still has room to improve even after wearing glasses.
ShanghaiAges 5–55 - NCT06914778Recruiting
How diabetes affects the eyes in South Wales
This study looks at how fat and sugar levels in the blood relate to different stages of eye damage in people with type 2 diabetes. It may help find new ways to treat or prevent vision loss.
Llanelli, WalesAges 18–80 - NCT06450470RecruitingPhase 3
Amniotic membrane after crosslinking for progressive keratoconus
This trial tests if placing a special freeze-dried amniotic membrane on the eye after crosslinking surgery helps improve healing and comfort for people with progressive keratoconus, a condition where the cornea thins and bulges.
BrestAges 18–65 - NCT07205887RecruitingPhase 2
Study of EYE103 for wet AMD or macular edema after BRVO
This trial tests an investigational drug called EYE103 injected into the eye to treat two conditions: wet age-related macular degeneration (AMD) or macular edema following a branch retinal vein occlusion (BRVO). It looks at how safe and effective the drug is for people who have not had treatment before or have not responded well to previous treatments.
Scottsdale, ArizonaAges 18 years+ - NCT07206628Recruiting
Glaucoma eye drop adherence with easygrip bottle
This study looks at how well people stick to their glaucoma eye drop routine when using a special bottle called EASYGRIP®. If you use this type of bottle for your glaucoma drops, this study may help doctors understand how to make treatment easier.
BolognaAges 18 years+ - NCT06924944Recruiting
A study of a new lens for people who had laser eye surgery
This study looks at how well a type of artificial lens (Clareon Vivity) works for people who have had laser eye surgery in the past and now need cataract surgery. It aims to see if this lens gives good vision without glasses.
Ogden, UtahAges Any age - NCT07209410RecruitingPhase 4
Eye drops to reduce redness from glaucoma treatment
This trial tests if adding brimonidine eye drops can reduce eye redness caused by the glaucoma drops you are currently taking. It may help if you have been using netarsudil/latanoprost drops and have noticed redness.
Kansas City, MissouriAges 18–65 - NCT07208838Enrolling by invitation
Testing a new digital eye chart for vision in Bulgaria
This study checks if a new digital eye chart (DDIVAT) works as well as traditional paper charts for measuring distance vision. It includes Bulgarian-speaking adults and healthy volunteers.
PlovdivAges 18 years+ - NCT07203391RecruitingPhase 1
Tebentafusp and roginolisib for uveal melanoma
This trial tests a combination of two drugs, tebentafusp and roginolisib, for people with uveal melanoma that has spread or can't be removed. It aims to improve how long the immune system stays active against the cancer.
Sydney, New South WalesAges 18 years+ - NCT07212010Enrolling by invitation
Brain-related vision problems in children
This study looks at how brain injuries or abnormalities affect vision in children. It aims to better understand and diagnose cerebral visual impairment (CVI), a vision problem caused by brain issues rather than eye problems.
Cincinnati, OhioAges 6 months–6 years - NCT07206238Recruiting
Orbital blood vessel inflammation in optic nerve disease
This study uses MRI scans to look at inflammation in blood vessels around the eye in two conditions: giant cell arteritis (GCA, a type of blood vessel inflammation) and ischemic optic neuropathy (a condition where the optic nerve doesn't get enough blood). The goal is to better understand how inflammation affects the optic nerve and vision, which could help guide future treatments.
Glostrup MunicipalityAges 50 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.