Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06249438RecruitingPhase 1
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new CAR-T cell therapy (C-CAR168) for people with several autoimmune diseases that have not responded to standard treatments. It aims to see if this therapy can control the disease when other medicines have failed.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06257082Recruiting
Video education for diabetic eye screening in Latinx communities
This study tests video-based education to help Latinx people with diabetes get regular eye exams, which can prevent vision loss. You may be able to join if you are Hispanic or Latino and have diabetes.
Madison, WisconsinAges 18 years+ - NCT06257355RecruitingPhase 1
Testing a new eye drop for corneal scars
This trial tests a new eye drop to see if it can safely and effectively reduce corneal scars. It is for people who have a recent corneal injury (within the last month) that resulted in a scar that affects their vision.
Loma Linda, CaliforniaAges 18–80 - NCT06261346Recruiting
Growth factors in corneal transplant surgery
This study tests whether adding a special growth factor solution to the fluid used during corneal transplant surgery helps the transplant heal better. It is for patients undergoing a specific type of corneal transplant called DSEK or DMEK.
Miami, FloridaAges 18–80 - NCT06263998RecruitingPhase 1
Safety study of NCP112 eye drops in healthy adults
This study tests a new eye drop called NCP112 for safety and how well people tolerate it. Healthy volunteers receive the eye drops and are monitored for any side effects.
Seoul, Daehak-ro, Jongno-guAges 19–50 - NCT06264024Recruiting
Combined laser and crosslinking for keratoconus
This trial tests a new combined treatment for keratoconus that includes both a surface laser (phototherapeutic keratectomy) and corneal collagen crosslinking (CXL). It may help strengthen your cornea and improve vision.
OsloAges 18 years+ - NCT06264427Recruiting
Study of metabolism issues in Greenland
This study looks at the genes and physical traits of people in Greenland with type 2 diabetes or severe obesity. It aims to better understand these conditions to improve care.
Nuuk, SermersooqAges 18 years+ - NCT06265298Recruiting
Using cheek tissue to repair the eye surface
This study is testing a new way to use a small piece of your cheek tissue to repair the surface of your eye. It may help people with certain eye conditions, like recurring growths, tumors, or burns.
Montpellier, OccitanieAges 18 years+ - NCT06265363Recruiting
Eye screening study for heavier or older premature babies
This study looks at how often premature babies weighing more than 1500 grams or born at 33 weeks or later get a serious eye condition called ROP (retinopathy of prematurity). It aims to find out what puts these babies at risk and what happens to them, helping doctors improve screening guidelines.
AnkaraAges 4 weeks+ - NCT06267274RecruitingPhase 1
Comparing two forms of bimatoprost for glaucoma or high eye pressure
This trial tests whether a new formulation of bimatoprost works as well as an existing one to lower eye pressure in people with chronic open-angle glaucoma or ocular hypertension. It involves multiple eye drop doses and checks for safety and effectiveness.
Bakersfield, CaliforniaAges 18 years+ - NCT06271330Recruiting
Switching older injections to faricimab for wet AMD
This study looks at people with wet AMD who have been getting regular eye injections of either aflibercept or ranibizumab for over a year. The goal is to see what happens when they switch to a newer injection called faricimab.
Nantes, NantesAges 18 years+ - NCT06273748Recruiting
Study on chronic eye inflammation in children
This study looks at children with long-term eye inflammation that is not caused by an infection. It aims to learn more about the condition and how to better help patients.
Kansas City, KansasAges 1–16 - NCT06274593Recruiting
Eye Imaging Study for Advanced Glaucoma
This study uses a special imaging test (OCT angiography) to look at blood flow around the optic nerve in people with advanced glaucoma. It aims to better understand how glaucoma affects eye circulation, which may help improve future care.
Nantes, NantesAges 18 years+ - NCT06275373Recruiting
Teprotumumab for thyroid eye disease study
This study tests if the drug teprotumumab can help with symptoms of thyroid eye disease, such as bulging eyes, pain, or double vision. It is for adults who are beneficiaries of the Department of Defense (DOD).
Bethesda, MarylandAges 18 years+ - NCT06278974Recruiting
Comparing myopia treatments for kids: glasses vs ortho-k
This study compares three ways to slow down nearsightedness in children: special glasses (defocus lenses), regular glasses, and orthokeratology contact lenses (worn overnight). It aims to find which works best for kids who have never worn glasses before.
Shenyang, LiaoningAges 7–17 - NCT06280755Recruiting
AI-assisted MS care study
This study looks at how artificial intelligence (AI) can help doctors care for people with multiple sclerosis (MS) and other similar conditions. It uses existing medical data to see if AI can improve treatment decisions.
Prague, Praha 2Ages 18 years+ - NCT06282848Recruiting
Myopia treatments for children ages 7 to 9
This study compares different ways to slow down nearsightedness (myopia) in children, including eyedrops and other treatments. It is designed for kids whose vision is getting worse and who are willing to join for 2 years.
Hong KongAges 7–9 - NCT06285539RecruitingPhase 2
Testing a drug for rare inflammatory diseases
This trial is testing a new drug (a JAK inhibitor) for people with rare inflammatory diseases like Behçet's, myositis, or IgG4-related disease that hasn't improved with standard treatments. The goal is to see if it can help control symptoms and reduce inflammation.
AmsterdamAges 18–65 - NCT06287645Recruiting
Eye photos for diabetes patients
This trial takes colored photos of the back of your eye to help experts identify diabetes-related changes. It may help detect eye problems early in people with diabetes.
KarachiAges 20 years+ - NCT06289491Recruiting
Hydrus Microstent vs Goniotomy during cataract surgery
This study compares two procedures done during cataract surgery: placing a tiny stent (Hydrus Microstent) or performing a goniotomy (a small cut in the eye's drainage tissue). Both aim to lower eye pressure in people with mild to moderate open-angle glaucoma.
Boston, MassachusettsAges 40–85 - NCT06291350Recruiting
Mouth bacteria in gum disease with blistering condition
This study looks at the bacteria in the mouth and gut of people with a blistering gum condition (mucous membrane pemphigoid) and gum disease. It aims to understand if certain bacteria are linked to the disease, which could lead to better treatments.
NiceAges 18 years+ - NCT06291818Recruiting
Magnetic device for treating eye exposure
This study tests a new magnetic device that sticks to your eyelid to help protect the eye when you can't fully close it. It may be an option if you have a recent scratch on your eye and trouble closing your eyelids.
Chicago, IllinoisAges 18–80 - NCT06291935RecruitingPhase 1
Gene therapy trial for retinitis pigmentosa with CNGA1 mutation
This trial tests a new gene therapy called VG901, given as an injection into the eye, for people with retinitis pigmentosa caused by a specific genetic change in the CNGA1 gene. The goal is to see if it is safe and tolerable.
TübingenAges 18 years+ - NCT06292650RecruitingEarly Phase 1
Gene therapy ZM-02 for advanced retinitis pigmentosa
This experimental gene therapy (ZM-02) is designed for people with advanced retinitis pigmentosa who have very poor vision (counting fingers or worse). It aims to see if the treatment is safe and can improve vision by replacing a faulty gene in the retina.
Beijing, Beijing MunicipalityAges 18–65
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.