Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07236762RecruitingPhase 1
YTS109 cell therapy for severe autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with severe autoimmune diseases like lupus, Sjögren's syndrome, systemic sclerosis, inflammatory myopathy, vasculitis, and antiphospholipid syndrome. It's for those whose disease hasn't improved with standard treatments.
BengbuAges 18–65 - NCT07232615Recruiting
Comparing two types of trifocal lenses for cataract surgery
This study compares two different trifocal toric intraocular lenses (special lenses that correct both near, far, and astigmatism) used during cataract surgery. Researchers want to see which lens gives better results for people with cataracts and astigmatism.
Düsseldorf, North Rhine-WestphaliaAges 21 years+ - NCT07235085RecruitingPhase 3
Study of OTX-TKI implant for moderate to severe NPDR
This study tests an eye implant (OTX-TKI) that slowly releases a medicine to slow or stop worsening of non-proliferative diabetic retinopathy (NPDR) — an early form of diabetic eye disease. It's for people with moderately severe to severe NPDR who haven't had significant treatments like laser or injections in that eye.
Hagerstown, MarylandAges 18 years+ - NCT07235592Recruiting
Preserflo MicroShunt study for open-angle glaucoma
This trial is testing a small device called the PRESERFLO MicroShunt to lower eye pressure in people with open-angle glaucoma. It may be an option if your eye pressure stays high even with maximum eye drops.
ViennaAges 18–85 - NCT07230834RecruitingPhase 1
Testing an injection for advanced dry AMD with geographic atrophy
This trial tests whether a monthly injection of pozelimab into the eye can slow the growth of geographic atrophy (a late form of dry age-related macular degeneration). It may help people who have significant vision loss from this condition.
Lakewood, ColoradoAges 50 years+ - NCT07237412Recruiting
Neurofeedback therapy for vision loss after stroke
This trial tests whether neurofeedback training can help restore vision in people who have lost part of their visual field due to a stroke. It aims to improve daily function and quality of life.
Bern, Canton of BernAges 50–70 - NCT07233616Recruiting
Radiofrequency ablation for chronic venous insufficiency in patients 80+
This study tests whether a procedure called radiofrequency ablation (using heat to close faulty veins) is safe and effective for people aged 80+ with chronic venous insufficiency. It aims to relieve symptoms like leg swelling, skin changes, or ulcers.
Chengdu, SichuanAges 80 years+ - NCT07236879Recruiting
AI eye test for diabetes patients in primary care
This trial uses an artificial intelligence (AI) system to check for diabetic eye disease (retinopathy) during your regular doctor visit. It aims to detect problems early so you can get treatment sooner.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07238387Recruiting
AR glasses for testing eye movements in vertigo patients
This trial tests whether a pair of AR glasses can help doctors check eye movements (nystagmus) in people with vertigo or dizziness. You would compare the new glasses with standard testing, and it might be more comfortable and wearable.
Kaohsiung, TaiwanAges 18 years+ - NCT07222150Recruiting
Comparing corneal clarity and thickness in cataract patients
This study looks at how clear and thick the cornea (the clear front part of the eye) is in people with cataracts. It may help doctors understand more about eye health during cataract treatment.
Matthews, North CarolinaAges 18 years+ - NCT07224542Enrolling by invitation
Smart contact lenses to monitor glaucoma
This study tests a smart contact lens that may help monitor glaucoma by measuring eye pressure. It is looking for people with glaucoma (who already use eye-drop medicine) and healthy adults without glaucoma to see if the lens works well over time.
Bloomington, IndianaAges 22 years+ - NCT07229001Enrolling by invitation
Treating Severe MGD in Children and Teens
This trial studies a treatment for severe Meibomian Gland Disease (MGD) in children and teens. MGD affects the tiny oil glands in your eyelids, which can cause dry, irritated eyes. The goal is to find a safe and effective way to help young patients with this condition.
Chicago, IllinoisAges 6–18 - NCT07223086Recruiting
Tinted contact lenses for concussion light sensitivity
This trial tests if special tinted contact lenses can help reduce light sensitivity caused by a concussion. It may help people who have had a mild concussion in the past two years and are bothered by light.
Birmingham, AlabamaAges 18 years+ - NCT07226141RecruitingPhase 1/Phase 2
Valproate for persistent lazy eye in children and teens
This trial tests if the medication valproate (a seizure drug) can improve vision in children and teens aged 8-17 who still have a lazy eye (amblyopia) even after wearing glasses or patching. It may help if your child's vision has stopped getting better with standard treatments.
Boston, MassachusettsAges 8–17 - NCT07225244Recruiting
Comparing balloon inflation points for tear duct surgery
This trial tests whether using four balloon inflation points during tear duct surgery works better than the standard two points for people with blocked tear ducts. It aims to improve tear drainage and reduce symptoms.
TaipeiAges 20 years+ - NCT07228221RecruitingPhase 4
Study of iStent and iDose for moderate to severe glaucoma
This trial studies a new treatment (a tiny device called iStent Infinite and a medication implant) for people with moderate to severe open-angle glaucoma who have not responded well to drops or laser. The goal is to see if this treatment can lower eye pressure and help avoid traditional surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07224529RecruitingPhase 4
Vevye eye drops for blocked oil glands in the eyelids
This study tests if Vevye eye drops can improve symptoms of meibomian gland dysfunction, a condition where the tiny oil glands in your eyelids get blocked. It may help reduce dryness and discomfort.
Birmingham, AlabamaAges 18 years+ - NCT07228793Recruiting
A study tracking EYS-related retinitis pigmentosa over time
This study follows people with retinitis pigmentosa caused by changes in the EYS gene over 4 years. It collects data on how the disease progresses and does not test any new treatments.
MoscowAges 14–100 - NCT07228091Recruiting
Surgery efficiency study for combined eye procedures
This study looks at how efficiently surgeons perform a combined cataract and vitrectomy surgery. It may help improve future surgical techniques. You may qualify if you are already scheduled for this specific type of eye surgery.
ManchesterAges 18 years+ - NCT07222293Recruiting
Testing an AI tool to screen for diabetic eye disease
This study uses an AI program called DRISTi to screen for diabetic eye disease by taking pictures of the back of your eye. It's designed for adults with diabetes who haven't had major eye treatments or vision loss.
Oxford, North CarolinaAges 21 years+ - NCT07229352Recruiting
How kids see and move with special glasses
This study looks at how well children can see and move while wearing special glasses for myopia (nearsightedness). It helps researchers understand if the glasses improve daily activities.
Glendale, ArizonaAges 6–12 - NCT07229365Recruiting
Kids' daily activities and vision study
This study looks at what children do every day and how it relates to their vision. It may help understand why some children need glasses.
Bloomington, IndianaAges 7–14 - NCT05904301Recruiting
Registry for autoimmune and autoinflammatory disease patients
This study builds a nationwide list (registry) of people with certain autoimmune or inflammation-related illnesses. It helps researchers understand these diseases better over time, which can guide future care.
YerevanAges Any age - NCT06145893RecruitingPhase 3
Hemay005 for Behçet's disease mouth sores
This study tests a new pill called Hemay005 for adults with Behçet's disease who have at least two mouth sores that need treatment beyond creams or rinses. It aims to see if the drug safely reduces mouth ulcers.
Beijing, Beijing MunicipalityAges 18–75
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.