Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07203391RecruitingPhase 1
Tebentafusp and roginolisib for uveal melanoma
This trial tests a combination of two drugs, tebentafusp and roginolisib, for people with uveal melanoma that has spread or can't be removed. It aims to improve how long the immune system stays active against the cancer.
Sydney, New South WalesAges 18 years+ - NCT06927375RecruitingPhase 4
Combination drug therapy for thyroid eye disease
This study tests a combination of two drugs, tocilizumab and flupentixol-melitracen, in people with active, moderate-to-severe thyroid-associated eye disease (TED). It aims to see if this combination can reduce eye bulging, double vision, and anxiety symptoms.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06755190Recruiting
AI help for eye disease decisions
This trial uses artificial intelligence to help doctors make better decisions about eye disease. It analyzes your medical records and images to see how AI can improve care and track disease.
Zhuhai, GuangdongAges Any age - NCT06780709Recruiting
Wellness program for neuromyelitis optica patients
This trial tests a structured wellness program to improve quality of life for people with neuromyelitis optica (NMOSD). It is designed to be accessible for any level of disability.
New York, New YorkAges 18 years+ - NCT06926686Recruiting
Tissue graft vs own cartilage for lower eyelid lift
This study compares two different surgical materials to fix a lower eyelid that is sagging or pulled down. It uses either a donated tissue product (acellular dermal matrix) or a piece of your own eyelid cartilage to help lift the eyelid back into place.
Bergen, VetslandetAges 18–75 - NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+ - NCT05786196Recruiting
Testing canaloplasty surgery for mild to moderate glaucoma
This study tests how well a specific glaucoma surgery (canaloplasty) works on its own for people with mild to moderate primary open-angle glaucoma. It may help if drops (eye medicines) do not work well for you or you need fewer eye drops.
DüsseldorfAges 22 years+ - NCT06933836Recruiting
DSLT laser for newly diagnosed open-angle glaucoma
This trial tests a laser treatment called DSLT in people recently diagnosed with open-angle glaucoma who have never had any other glaucoma treatment. It aims to see how well the laser lowers eye pressure.
Mesa, ArizonaAges 30 years+ - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT07201298Recruiting
Comparing laser eye surgery methods for nearsightedness
This study compares a new type of laser surgery (ray-tracing guided) to three other standard laser methods for correcting nearsightedness with or without astigmatism. It aims to see which approach provides the best vision correction.
Draper, UtahAges 22–50 - NCT07198126Enrolling by invitation
How pterygium surgery changes corneal curvature in astigmatism
This trial compares how the curve of your cornea (which affects vision) changes before and after surgery to remove a pterygium—a fleshy growth on the eye—and repair the area with your own tissue. It is for adults with moderate to advanced pterygium that has already caused astigmatism.
Lahore, Punjab ProvinceAges 30–70 - NCT06821074Recruiting
Special glasses vs. regular glasses for slowing nearsightedness in kids
This study compares special glasses designed to slow nearsightedness (myopia) with regular glasses in children and teens. It aims to see which type better protects your child's eyesight over time.
BeijingAges 6–18 - NCT06941584Recruiting
AIRE gene's role in autoimmune nerve diseases
This study looks at how the AIRE gene affects people with autoimmune nerve diseases like NMOSD, myasthenia gravis, and autoimmune encephalitis when they also have other autoimmune conditions. It may help researchers understand why some people get multiple autoimmune problems.
RomaAges 18 years+ - NCT06942520RecruitingPhase 2
Gene therapy for diabetic macular edema in adults
This trial tests a gene therapy called RGX-314 for people with diabetic macular edema that affects the center of the vision. If you have had previous treatment and still have swelling, this study may be an option.
Reno, NevadaAges 25–89 - NCT07185971Recruiting
Vision training system for chronic vision loss after brain injury
This study tests a device called PAVE that may help improve vision in people who have lost part of their sight due to stroke, brain injury, or brain surgery. It is for those with ongoing vision problems, not those with eye diseases.
Cedar Rapids, IowaAges 21–80 - NCT07185841RecruitingPhase 1/Phase 2
Oral tablets for wet macular degeneration
This trial tests an experimental oral tablet for people with wet age-related macular degeneration. It may offer a new way to treat the condition without frequent eye injections.
BeijingAges 50–85 - NCT07191847RecruitingPhase 4
Stem cell eye drops for dry eye disease
This trial tests whether stem cell fortified eye drops can improve tear film stability, tear volume, and dry eye symptoms. If you have dry eye disease and haven't had eye surgery or certain other eye conditions, you may be able to join.
GizaAges 18–80 - NCT07189169RecruitingPhase 3
Testing QA108 for intermediate AMD
This trial tests an investigational medicine (QA108) for people with intermediate age-related macular degeneration (AMD). It aims to slow or prevent progression of the disease by treating the deposits (drusen) in the center of the retina.
BeijingAges 45–85 - NCT07185256RecruitingPhase 1/Phase 2
Gene therapy for Best disease retinal trial
This trial tests a gene therapy called OPGx-BEST1 injected under the retina to treat vision loss from Best vitelliform macular dystrophy or a related condition. It may help people with advanced disease who have a specific genetic change in the BEST1 gene.
Los Angeles, CaliforniaAges 18 years+ - NCT06787482RecruitingPhase 1/Phase 2
Peptide therapy for retinitis pigmentosa
This trial tests a new peptide therapy for people with retinitis pigmentosa (RP), a genetic eye disease that causes vision loss. The goal is to see if the treatment is safe and can help slow or improve vision loss.
CairoAges Any age - NCT06944171Recruiting
How brain-related challenges affect daily life in children with cerebral palsy
This study looks at how impairments like muscle stiffness or weakness affect daily activities and participation in children (ages 6–12) with cerebral palsy. It could help families better understand their child's needs.
AnkaraAges 6–12 - NCT07185347RecruitingPhase 3
Fampridine for SCA27B ataxia study
This trial tests if fampridine, a medication, can improve walking and coordination in people with SCA27B, a specific inherited ataxia. It compares fampridine to a placebo over a period of time.
AngersAges 18 years+ - NCT07183891Recruiting
Testing AI to analyze eye surgery results
This trial tests whether large language models can accurately analyze eye surgery data and predict how well patients see after surgery. It focuses on patients who had good vision and stable lens implants one month after cataract surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06936787RecruitingPhase 1
Study of IGT001 for retinitis pigmentosa
This trial tests an experimental drug called IGT001 for people with retinitis pigmentosa, a genetic eye disease that causes vision loss. The goal is to see if it is safe and can help slow or improve vision.
ShanghaiAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.