Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06996353Recruiting
A study of laser eye correction for nearsightedness
This study is collecting health information from people who have undergone a specific laser eye correction procedure (PTK-PRK) for nearsightedness with or without astigmatism. It aims to understand how well the treatment works and how safe it is.
Chandigarh, Punjab HaryanaAges Any age - NCT06984822Recruiting
Comparing eye injections for diabetic macular edema
This study compares two different eye injection treatments for diabetic macular edema (DME)—a condition where fluid builds up in the center of the retina, blurring vision. Researchers want to see how certain measures in the blood and in eye scans relate to how well each treatment works.
MölndalAges 18 years+ - NCT06985264Enrolling by invitation
Dry eye after upper eyelid surgery: muscle vs fat removal
This trial compares how two different upper eyelid surgery techniques—removing muscle versus removing fat—affect dry eye symptoms after surgery. It may help you understand which approach is better for your eye health.
Mersin, ÇukurovaAges 18–80 - NCT06990074Recruiting
Study of the Polaris System for cataract surgery
This trial tests a new system called Polaris for removing cataracts and implanting a lens. It is for people with age-related cataracts who are healthy enough for routine cataract surgery.
San Salvador, San Salvador DepartmentAges 40–75 - NCT06990399RecruitingPhase 3
Testing KSI-101 eye injections for swelling from inflammation
This trial tests a new injected medicine (KSI-101) for people with swelling in the back of the eye caused by inflammation. The medicine is given directly into the eye to see if it can reduce the swelling and improve vision.
Phoenix, ArizonaAges 18 years+ - NCT06990269RecruitingPhase 2
Study of ADX-038 for geographic atrophy in dry AMD
This trial tests an investigational drug (ADX-038) for people with geographic atrophy, a form of advanced dry age-related macular degeneration. The drug is given as an injection into the eye, and the study checks if it can slow down the growth of GA spots.
Gilbert, ArizonaAges 60 years+ - NCT06987474Recruiting
Eye health research study for device testing
This study tests a new device to capture data from your eyes. It helps researchers learn how well the device works for different people.
BangaloreAges 18 years+ - NCT06984627RecruitingPhase 2
Study of Rilzabrutinib for Adults with Graves' Disease
This study tests an experimental pill called rilzabrutinib for people with Graves' disease, a condition where the immune system attacks the thyroid. It aims to see if the drug can help control the overactive thyroid and any related eye problems.
Buenos AiresAges 18–75 - NCT06991114RecruitingPhase 2
AlloNK and rituximab for relapsing rheumatologic diseases
This trial tests a new natural killer (NK) cell therapy called AlloNK given with rituximab for people with certain autoimmune diseases (rheumatoid arthritis, Sjögren's disease, inflammatory myopathies, or systemic sclerosis) that have not responded well to standard treatments. The goal is to see if this combination can better control the disease.
Tuscaloosa, AlabamaAges 18 years+ - NCT06991712RecruitingPhase 2
NAD supplements for nerve health in glaucoma
This trial tests whether NAD precursor supplements can improve nerve health and vision in people with glaucoma. If you have glaucoma with mild to moderate vision loss, this study may help understand if these supplements could protect your optic nerve.
Wong Chuk HangAges 18 years+ - NCT06985706RecruitingPhase 3
Comparing two treatments for diabetic eye swelling after initial injections
This trial tests whether switching from anti-VEGF injections to a special laser is better than continuing injections alone for people with diabetic macular edema whose central retinal thickness has dropped below 400 microns after the first year of treatment.
BedfordAges 18 years+ - NCT06977724RecruitingPhase 1
Testing a new drug for lupus, sjogren's, and rheumatoid arthritis
This study tests an experimental medicine given by IV infusion to see if it is safe and helps reduce symptoms of lupus, sjogren's disease, or rheumatoid arthritis. It is an early-phase trial, so the main goals are checking side effects and how the drug behaves in the body, but it will also look at how well it works.
Avon Park, FloridaAges 18–75 - NCT06980649RecruitingPhase 1
Study of BHV-1300 in Graves' Disease
This trial tests a new treatment called BHV-1300 for people with Graves' disease. It aims to see if the drug is safe and works well. If you have Graves' disease confirmed by blood tests, you may be able to join.
South Gate, CaliforniaAges 18–65 - NCT06975748RecruitingPhase 2
Eye Drop for Nerve-Damaged Corneas
This trial tests an experimental eye drop (STSP-0902) for a condition called neurotrophic keratitis, where the cornea (the clear front part of the eye) gets scratches or sores because nerves are damaged. The drop contains a growth factor to help the eye heal. You might be eligible if you have a persistent scratch or sore on your cornea that has not improved for at least a week.
Jinan, ShandongAges 18–85 - NCT06979752Recruiting
Testing a new cannula for glaucoma-cataract surgery
This trial tests whether a special cannula can help protect the eye during combined surgery for pseudoexfoliative glaucoma (a type of glaucoma with flaky deposits) and cataracts. It may offer better results than standard irrigation.
AvranchesAges 18 years+ - NCT06974162Recruiting
Decoding eye inflammation with genetic sequencing
This trial uses a new genetic test to find the cause of eye inflammation when standard tests haven't. The goal is to see if this approach can identify hidden infections and help doctors choose the right treatment to protect your vision.
LondonAges Any age - NCT06982105RecruitingPhase 4
Comparing two antibiotics for children with MRSA bone or head infections
This study compares two oral antibiotics, TMP-SMX and clindamycin, to see which works better for children with MRSA infections in bones, joints, or head/neck areas. It aims to find the best treatment after initial IV therapy.
Indianapolis, IndianaAges 2 months–18 years - NCT06970106RecruitingPhase 1/Phase 2
Study of PYC-001 eye injections for people with a type of inherited optic nerve disease
This trial tests a new medicine called PYC-001, given as an injection into the eye, for people with a specific genetic form of vision loss called autosomal dominant optic atrophy (ADOA). It aims to see if the treatment is safe and could help protect or improve vision.
Sydney, New South WalesAges 18 years+ - NCT06971939RecruitingPhase 4
Long-term safety of NT-501 implant for MacTel type 2
This study checks the long-term safety and effectiveness of the NT-501 implant for people with MacTel type 2. It is for people who have already been in an earlier NT-501 study, whether they got the real implant or a sham procedure.
La Jolla, CaliforniaAges 18 years+ - NCT06968611Recruiting
Diabetes and vision care study in Bangladesh
This study tests a program that combines diabetes care with eye exams for people in Bangladesh who were recently diagnosed with diabetes. The goal is to see if this approach helps you better manage your health and prevent vision problems.
DinajpurAges 30 years+ - NCT06963203Recruiting
Surgery for hyperthyroidism from Graves' or amiodarone use
This study looks at thyroid removal surgery for hyperthyroidism caused by Graves' disease or the heart medication amiodarone. It aims to see how well the surgery works for these patients.
AalstAges 18 years+ - NCT06966167Recruiting
Laser vs. standard cataract surgery in Fuchs' dystrophy
This study compares two types of cataract surgery in people with Fuchs' dystrophy: one using a laser and the standard method. It looks at which approach gives better results for the cornea and vision.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT06969586Enrolling by invitation
Eye drops study for Fuchs corneal disease and glaucoma
This study tests whether special eye drops (Rho-kinase inhibitors) can improve the health of the cornea in people who have both Fuchs endothelial corneal dystrophy and glaucoma. The drops may help reduce corneal swelling and preserve your vision.
Zagreb, CroatiaAges 40–90 - NCT06965426Recruiting
Eye vitamins and skin test: a crossover study
This study tests whether a supplement containing lutein, zeaxanthin, and meso-zeaxanthin can increase the amount of these nutrients in your skin. You will take the supplement and a placebo at different times to see if there is a difference.
Kansas City, MissouriAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.