Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07350330Recruiting
Muscle transplant vs Y-split for large exotropia
This study compares two surgical methods to treat large-angle outward eye turning (exotropia) in patients over 6 years old. The surgery aims to correct eye alignment, and the trial helps find which technique works best.
CairoAges 6 years+ - NCT07351786Recruiting
Newer diabetes drugs and eye protection study
This trial is looking at whether newer diabetes drugs (like SGLT2 inhibitors and DPP-4 inhibitors) can help protect the eyes of people with long-standing type 2 diabetes. The study focuses on preventing or slowing diabetic retinopathy, a common eye complication.
AlexandriaAges 25 years+ - NCT07354009Recruiting
Stent implant for lowering eye pressure in open-angle glaucoma
This trial tests a small stent to help drain fluid from the eye and lower pressure in people who have both open-angle glaucoma and cataracts. The stent is placed during routine cataract surgery.
HangzhouAges 18–90 - NCT07354945Recruiting
Study of myopia control lenses in children
This study tests how well children adapt to special myopia control lenses. It aims to see if these lenses are comfortable and easy to wear for kids with nearsightedness.
Shanghai, Shanghai MunicipalityAges 6–12 - NCT07358650Recruiting
MIST device for lowering eye pressure in glaucoma
This study tests a new device called MIST that is placed inside the eye to help lower eye pressure in people with primary open-angle glaucoma. It may be an option for those whose pressure is still too high despite using eye drops.
Dieppe, New BrunswickAges 40 years+ - NCT07358832Recruiting
Brain stimulation for vision loss after recent brain injury
This trial tests whether combining brain stimulation with visual exercises can help improve vision loss caused by a recent brain injury. It is designed for people in the early recovery phase (within 3 months of injury) who have visual field deficits, but not other conditions like neglect or eye movement problems.
Milan, LombardyAges 18 years+ - NCT07359547Recruiting
Comparing Two Glaucoma Drainage Devices
This trial compares two different tiny drainage devices (a gel stent and a microshunt) for lowering eye pressure in people with certain types of glaucoma that are not well controlled with medications. The goal is to see which device works better and is safer.
Leuven, Vlaams-brabantAges 40 years+ - NCT07361094RecruitingPhase 1
CAR-T therapy for autoimmune disease after prior treatment
This trial tests a new CAR-T cell therapy that targets two proteins (CD19 and BCMA) on immune cells. It is for people with certain autoimmune diseases (like lupus or scleroderma) that have not responded well to standard treatments or have relapsed after prior cell therapy.
BeijingAges 18–70 - NCT07363824Recruiting
Tear iron and dry eye severity study
This study looks at how iron levels in tears relate to the severity of dry eye disease. It aims to find a simple way to measure dry eye severity, which could help doctors better understand and treat the condition.
ShanghaiAges 18–70 - NCT07363889Recruiting
Spring syringe removal of silicone oil
This trial uses a special spring-loaded syringe to remove silicone oil from the eye after a previous vitrectomy surgery. It may offer a simpler way to take out the oil for people who don't have certain eye problems.
Sohag, Sohag GovernorateAges 18 years+ - NCT07364474Recruiting
Immune response to liver perfusion therapy for eye melanoma
This study tests how well the liver responds to a treatment called percutaneous hepatic perfusion with melphalan (chemotherapy delivered directly to the liver) in people with uveal melanoma that has spread to the liver. The goal is to see how the immune system reacts and if the treatment helps control the disease.
Boston, MassachusettsAges 18 years+ - NCT07364929Recruiting
Glaucoma and its effects on sleep, mood, and thinking
This study looks at how glaucoma affects your body's natural light sensing, which can impact sleep, alertness, mood, and memory. Researchers compare people with glaucoma to healthy volunteers to understand these effects better.
SingaporeAges 45–75 - NCT07366944Recruiting
PCOS, eye dryness, and lifestyle changes trial
This trial tests if lifestyle changes can help with eye dryness in women with PCOS and obesity. It looks for improvements in dry eye symptoms.
Giza, DokkiAges 30–40 - NCT07368959RecruitingPhase 3
New treatment for corneal swelling needing surgery
This trial tests a new treatment for people with corneal swelling that needs surgery. It helps replace the inner layer of the cornea to improve vision.
Mesa, ArizonaAges 18 years+ - NCT07369063RecruitingPhase 2
Vitamin D for pediatric Graves' disease
This study tests whether adding vitamin D therapy to the usual Graves' disease treatment (methimazole) can improve thyroid function and lower antibody levels in children. If your child is between 9 and 17 and recently diagnosed, they may be able to participate.
New Hyde Park, New YorkAges 9–17 - NCT07369804Recruiting
Red-light therapy for myopia in adults
This study tests whether a special red-light device can safely slow or stop nearsightedness from getting worse in adults. You'll use the light at home for a few minutes each day, and the team will check your vision over time.
Hong Kong, Hong KongAges 18–50 - NCT07370584RecruitingPhase 1
Safety study of IVMED-85 eye drops in healthy adults
This phase 1 trial tests the safety of an investigational eye drop called IVMED-85 in healthy adults aged 18-49. Participants will receive the eye drops and be monitored for any side effects over 6 weeks.
Memphis, TennesseeAges 18–49 - NCT07371468RecruitingPhase 1
Study of an experimental drug for lupus, rheumatoid arthritis, and related conditions
This trial tests a new drug called GSK5926371 for people with certain autoimmune diseases that affect the joints, skin, and other tissues. It aims to see if the drug is safe and how well it works.
Buenos AiresAges 18–70 - NCT07372911Recruiting
Comparing two cornea treatments for keratoconus
This trial tests two different laser-based procedures to treat keratoconus, a condition that weakens and bulges the cornea. The goal is to see which approach better strengthens the eye and improves vision.
Mexico City, Mexico CityAges 18 years+ - NCT07373821Recruiting
Lying face up after cornea transplant surgery
This study tests if lying face up after DMEK surgery (a cornea transplant for Fuchs dystrophy) helps the surgery work better. It may be an option for people with Fuchs dystrophy or bullous keratopathy who can lie flat on their back.
HeidelbergAges Any age - NCT07375940Recruiting
Understanding Behçet Disease in children and teens
This study looks at the health records and blood tests of children and young adults with Behçet disease to learn more about the condition. It also compares their results with healthy children to find clues that may help doctors better understand and treat Behçet disease.
Florence, FlorenceAges 6 months–70 years - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT07377305Recruiting
Brain stimulation for nerve pain in NMOSD
This trial tests a new, non-invasive brain stimulation method (tTIS) to treat chronic nerve pain in people with neuromyelitis optica spectrum disorder (NMOSD). It aims to see if this treatment is safe and can reduce pain without surgery or drugs.
Xi'an, ShaanxiAges 18–75 - NCT07377513Recruiting
Can text reminders help corneal ulcer patients follow up?
This study tests if sending SMS reminders helps patients with corneal ulcers keep their follow-up appointments. It may help you stay on track with treatment and prevent complications.
Siddharthanagar, LumbiniAges 18–70
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.