Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT03517579Recruiting
Personalized treatment for Graves and certain thyroid cancers
This trial tests a personalized approach to treat thyroid disorders, either Graves’ disease or certain thyroid cancers that may need radioactive iodine treatment. It may help by matching treatment to your specific test results and needs.
Baltimore, MarylandAges 21–65 - NCT06109909Recruiting
Brain training for light sensitivity after mild head injury
This study tests if a type of brain training called neurofeedback can help reduce sensitivity to light in people who have had a mild traumatic brain injury, also known as a concussion, at least 6 months ago.
Boston, MassachusettsAges 18–65 - NCT04627428RecruitingPhase 1/Phase 2
Stem-cell–made eye tissue transplant for dry macular degeneration
This early-stage study tests whether a stem-cell–derived transplant to the back of the eye is safe and tolerable in people with dry age-related macular degeneration (AMD). If you qualify, you may receive the transplant and have close follow-up to watch for side effects.
Beverly Hills, CaliforniaAges 55 years+ - NCT06121180RecruitingPhase 2
Cemiplimab plus ziv-aflibercept for metastatic uveal melanoma
This trial tests two drugs, cemiplimab and ziv-aflibercept, together for people whose uveal melanoma has spread. It may be an option if previous treatments have stopped working or you haven't had treatment yet.
Los Angeles, CaliforniaAges 18 years+ - NCT06121219Recruiting
Can visual retraining after stroke improve sight?
This trial tests whether special computer-based visual exercises can help people whose vision was damaged by a stroke. You would do the exercises at home for several months.
Rochester, New YorkAges 21–80 - NCT06124521Recruiting
Community glaucoma support study for Black adults
This study tests a way to help Black adults in Michigan manage glaucoma through a community church program. It’s for those who already had a screening eye exam and want support staying on top of their eye health.
Ann Arbor, MichiganAges 40 years+ - NCT06105892Recruiting
Eye recovery program for mild brain injury symptoms
This study tests a home-based eye exercise program for people with mild traumatic brain injury who have ongoing vision problems like blurring or trouble focusing. It aims to help your eyes work together better and reduce symptoms.
Albuquerque, New MexicoAges 18–40 - NCT06128720Recruiting
Hyperbaric oxygen therapy for optic nerve damage
This study tests if breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help people with optic neuropathy, a condition that damages the nerve connecting the eye to the brain.
Palo Alto, CaliforniaAges 18 years+ - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT06107881Recruiting
Testing sensors and rehab to help improve use of low-vision devices
This study tests if small sensors attached to magnifiers and remote rehab sessions can help people with low vision use their new devices more. You may join if you recently got a magnifier or vision app and can attend visits.
Fullerton, CaliforniaAges 18 years+ - NCT06117332Enrolling by invitation
AI-Enhanced Vision for People with Visual Implants
This study tests a new AI system designed to improve what people with visual prostheses 'see.' If you have an implanted device like the Argus II or Orion, you may be able to help by coming to the lab for several days of vision testing.
Santa Barbara, CaliforniaAges 18 years+ - NCT04094090RecruitingPhase 2
Corneal strengthening treatment for thinning eye shape
This Phase 2 study tests how safe and well a corneal cross-linking device (called PXL-Platinum 330) works for people with corneal ectasia (a thinning/steepening of the cornea). If you qualify, the goal is to help stop or slow further worsening of your cornea shape and improve eye stability.
San Francisco, CaliforniaAges 10 years+ - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT06081439Recruiting
Immune markers and mental fatigue in Graves' disease
This study looks at whether certain immune system markers are linked to mental fatigue (feeling tired or foggy in the mind) in people with newly diagnosed Graves' disease. If you join, you'll help researchers understand how your immune system might affect your energy and thinking.
GothenburgAges 18–72 - NCT00221897Recruiting
Eye test study to help diagnose glaucoma
This study tests new ways to evaluate eyes to help diagnose glaucoma and related eye conditions. You may be able to join if you’re an adult with normal eye health or with concerns like myopia, glaucoma suspicion, or ocular hypertension.
La Jolla, CaliforniaAges 18 years+ - NCT05999630RecruitingPhase 3
Artificial tears to prevent tear duct blockage during RAI therapy
This study tests if using artificial tears (eye drops that keep your eyes moist) can prevent tear duct blockage in people receiving high-dose radioactive iodine for thyroid cancer. If you qualify, you will use artificial tears during your treatment to see if they help keep your tear ducts open.
Nashville, TennesseeAges 18 years+ - NCT03933631RecruitingPhase 3
Pilocarpine eye drops after glaucoma drainage surgery
This trial tests whether pilocarpine eye drops work better after a specific glaucoma surgery called Kahook goniotomy done at the same time as cataract surgery. It may help lower eye pressure and support better glaucoma control after surgery.
The Bronx, New YorkAges 30–100 - NCT06066645RecruitingPhase 4
Travoprost implant plus iStent for glaucoma
This trial tests a tiny implant that slowly releases travoprost (a pressure-lowering medicine) inside the eye, combined with a small stent (iStent) to help drain fluid. It's for people with open-angle glaucoma or high eye pressure who need to lower their eye pressure.
Oklahoma City, OklahomaAges 18 years+ - NCT06060041Recruiting
Study of the IC-8 Apthera lens after cataract surgery
This study is for people who already have an IC-8 Apthera lens in one eye and need treatment for clouding on the lens capsule (posterior capsule opacification). It evaluates how well this lens works over time.
Dothan, AlabamaAges 22 years+ - NCT06070012RecruitingPhase 2
Tebentafusp for untreated metastatic uveal melanoma
This trial tests a new drug called tebentafusp for people with uveal melanoma that has spread to other parts of the body and who have not yet received any treatment for the metastatic disease. It requires a specific genetic marker (HLA-A*0201) and focuses on whether the drug can shrink or slow the growth of tumors.
Aurora, ColoradoAges 18 years+ - NCT01050296Recruiting
Study of tumor samples to guide treatment for childhood cancers
This study collects and studies tissue or bone marrow samples from certain childhood tumors. The goal is to learn what’s going on inside the cancer (using molecular testing) to better understand the disease and how it may respond to treatment.
Memphis, TennesseeAges Up to 25 years - NCT05888441Recruiting
Walking obstacle testing in people with and without vision trouble
This trial studies how people negotiate obstacles while walking, comparing those with normal vision and those with vision impairment. It may help researchers better understand balance and safety needs for walking in everyday settings.
Bloomington, IndianaAges 18 years+ - NCT06034327Recruiting
Testing a new spectacle lens for slowing myopia in kids 6–8
This study tests a special spectacle lens designed to slow the progression of nearsightedness (myopia) in children aged 6 to 8. It may be a good option for kids who are mildly to moderately nearsighted and haven't used other myopia control treatments.
Oakland, CaliforniaAges 6–8 - NCT06056154Enrolling by invitation
Testing a new artificial lens for cataract surgery
This trial tests a new type of artificial lens (called Asqelio Monofocal) for people having cataract surgery. The lens is designed to give clear distance vision without glasses.
AlicanteAges 22 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.