Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07378956Recruiting
AI eye screening for diabetes patients
This study uses an artificial intelligence (AI) tool to analyze eye images in people with type 2 diabetes. The goal is to see if the AI can help detect early signs of diabetic eye disease, so you can get the right care sooner.
Incheon, Gyeonggi-doAges 19 years+ - NCT07380256Recruiting
How vision affects balance and dizziness
This study looks at how vision problems and inner ear (vestibular) issues together affect balance. It aims to find better ways to help people with dizziness or balance problems.
Atlanta, GeorgiaAges 18–60 - NCT07381413Recruiting
Eye tracking study for thyroid eye disease
This study uses eye tracking to compare how people with thyroid eye disease move their eyes and pay attention to visual cues. It may help researchers understand eye movement problems better.
ShanghaiAges 18–70 - NCT07387159Recruiting
Studying MiYOSMART lenses to slow nearsightedness in kids
This trial tests whether special MiYOSMART iQ spectacle lenses can slow down worsening nearsightedness (myopia) in children. It aims to find a safe, non-invasive way to help kids see clearly longer.
MoscowAges 8–11 - NCT07389980RecruitingPhase 3
Personalized high-dose aflibercept for a type of wet AMD
This trial tests a higher dose of aflibercept (a drug that blocks abnormal blood vessel growth) for people with a specific form of wet age-related macular degeneration called polypoidal choroidal vasculopathy. The goal is to see if a personalized treatment plan with this stronger dose is safe and effective for those who have not been treated before.
DaeguAges 19 years+ - NCT07390500RecruitingPhase 2
Myopia control study for children using digital devices
This study tests a special lens designed to slow down nearsightedness (myopia) in children. It is for kids who spend at least one hour a day on screens and currently wear regular glasses.
RehovotAges 6–12 - NCT07390890Recruiting
DSLT to reduce glaucoma eye drops
This trial is testing a laser treatment called DSLT to see if it can help people with glaucoma use fewer eye drops. It may be a good option if your eye pressure is already controlled with medication and you haven't had glaucoma surgery before.
Largo, FloridaAges Any age - NCT07392411Recruiting
AI study of face and speech in Parkinson's disease
This study uses artificial intelligence to analyze facial expressions and speech patterns in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The goal is to find digital markers that may help track the disease.
Beijing, Beijing MunicipalityAges 15–75 - NCT07394257Recruiting
Antibiotic injection for hard-to-treat bacterial eye infection
This trial tests if an antibiotic injection directly into the cornea can help when standard eye drops are not working for a stubborn bacterial eye infection.
MinyaAges 20 years+ - NCT07396441RecruitingPhase 4
Kelulut honey therapy for juvenile glaucoma
This trial tests if adding Kelulut honey to standard treatment can help protect the optic nerve in young people with juvenile open-angle glaucoma. It looks at eye pressure, nerve thickness, and dry eye symptoms.
Kota Bharu, KelantanAges 15–40 - NCT01694940Recruiting
Mitochondrial disease registry and sample collection study
This trial builds a large database and collection of lab results, and possibly tissue samples, from people with suspected or diagnosed mitochondrial conditions. It helps researchers learn more about these disorders and mitochondrial DNA changes, which may improve future diagnosis and treatments.
San Diego, CaliforniaAges Any age - NCT01277419Recruiting
Study of new cases of several spine, joint, and eye diseases
This study enrolls people who have recently been diagnosed with certain inflammatory conditions affecting the spine, joints, or the eye. Researchers are looking to better understand how these illnesses start and how they may be linked, which could help guide future care.
BerlinAges Any age - NCT01050296Recruiting
Study of tumor samples to guide treatment for childhood cancers
This study collects and studies tissue or bone marrow samples from certain childhood tumors. The goal is to learn what’s going on inside the cancer (using molecular testing) to better understand the disease and how it may respond to treatment.
Memphis, TennesseeAges Up to 25 years - NCT00286637Recruiting
New tests to diagnose glaucoma and related eye problems
This study tests new ways to diagnose glaucoma (and sometimes related eye conditions) using eye exams and measurements. It may help improve how doctors detect glaucoma earlier and more accurately.
Philadelphia, PennsylvaniaAges 18 years+ - NCT00697411Recruiting
Study of Aicardi syndrome in X-linked disorders
This trial looks at people with features that suggest Aicardi syndrome, a rare condition that can affect the brain and eyes and may include seizures. Researchers want to better understand the condition and how it shows up, which may help guide care in the future.
Houston, TexasAges Any age - NCT00254605Recruiting
Retinal photo imaging for inherited eye conditions
This study uses special pictures of the back of your eye (retinal imaging) in people with inherited retinal degeneration. It may help researchers learn how these conditions look and change over time, and it can be a way for you to receive detailed eye imaging.
San Francisco, CaliforniaAges 13 years+ - NCT00001456Recruiting
Understanding Hermansky-Pudlak Syndrome: Research Study
This research study investigates Hermansky-Pudlak Syndrome (HPS), a rare genetic condition affecting blood clotting and skin color. Researchers are looking for people with HPS or their family caregivers to participate in clinical evaluations and questionnaires to better understand the condition.
Bethesda, MarylandAges 1 month–115 years - NCT01778543Recruiting
Study genes behind small eyes and eye coloboma
This study looks at how genes may cause certain eye conditions called microphthalmia, anophthalmia, and uveal coloboma. You may qualify if you have one of these conditions or are a close, unaffected relative who could also carry the gene.
Bethesda, MarylandAges 1–100 - NCT01866371Recruiting
High-detail eye scans for children and adults
This study tests a high-resolution imaging method that takes very detailed pictures of the retina (the light-sensing layer at the back of the eye). You might benefit by getting your eye health checked in a structured imaging study—if you’re able to comfortably complete the scan.
Philadelphia, PennsylvaniaAges 7 years+ - NCT00655096Recruiting
Eye disease study screening for participants and family controls
This trial is a general screening step for people who may have an eye (ocular) condition, or for family members of someone with an eye condition. The goal is to help match you to an eye research study by confirming your situation and whether you can safely participate.
Bethesda, MarylandAges 2–100 - NCT00221897Recruiting
Eye test study to help diagnose glaucoma
This study tests new ways to evaluate eyes to help diagnose glaucoma and related eye conditions. You may be able to join if you’re an adult with normal eye health or with concerns like myopia, glaucoma suspicion, or ocular hypertension.
La Jolla, CaliforniaAges 18 years+ - NCT01425892Recruiting
Study of how Sjogren’s disease starts and changes over time
This study follows people with Sjogren’s disease to understand how it develops and how symptoms naturally change over time. The goal is to improve understanding and future care rather than provide a new immediate treatment.
Bethesda, MarylandAges 16–100 - NCT00005917Recruiting
Understanding Chediak-Higashi Syndrome: A Research Study
This study helps researchers understand Chediak-Higashi syndrome, a rare genetic condition that affects how the body fights infections and controls bleeding. Participation involves medical evaluation and may help guide future treatments.
Bethesda, MarylandAges 1 month–70 years - NCT01403402Recruiting
Study of congenital muscle disease patients and their families
This trial collects health information from patients with certain inherited (genetic) muscle diseases and from their families. It may help researchers better understand the disease and improve care by learning what symptoms and treatments patients experience over time.
Lakewood, CaliforniaAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.