Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune disease
This trial tests whether the immunotherapy drug nivolumab can safely treat advanced cancer in people who also have an autoimmune disease like rheumatoid arthritis, lupus, or multiple sclerosis. It aims to find out if the drug may help control cancer while managing their autoimmune condition.
Birmingham, AlabamaAges 18 years+ - NCT03812016Recruiting
Feedback device for temporary eyelid droop treatment
This study tests a special device that uses feedback to temporarily manage blepharoptosis, which means a droopy upper eyelid. It may help improve eyelid position without permanent surgery, but you must be able to follow the study steps.
Kaohsiung CityAges 18–85 - NCT03752840Recruiting
Community eye-worker program in Nepal
This trial tests a village-based approach to bring eye care closer to older community members. If you live in the right area and are willing to participate, it may help improve access to eye screening and services.
San Francisco, CaliforniaAges 60 years+ - NCT03872102Recruiting
Brain imaging study to track Parkinson-related disease changes
This study uses brain scans and clinical check-ins to better diagnose and predict how Parkinson-related conditions may progress over time. It may help researchers find markers that explain why symptoms change, and could improve future care.
Dallas, TexasAges Any age - NCT03848663Recruiting
Training with visual remapping to help reading with central vision loss
This study tests whether a computer-based visual training method (“remapping”) can help people read better even when they have reduced central vision. You may benefit if your eye condition is stable and your eyes can reliably track the training on an eye-tracker.
Minneapolis, MinnesotaAges 16 years+ - NCT02593565Recruiting
Pregnancy blood-vessel disease registry study
This is a pregnancy registry that collects information from people with certain blood-vessel inflammatory diseases during pregnancy. It helps researchers better understand these conditions in pregnancy and may guide future care.
Tampa, FloridaAges 18–50 - NCT03686124RecruitingPhase 1/Phase 2
Tested immune therapy for certain HLA-A2 positive solid tumors
This trial studies an immune-based cancer treatment (IMA203/IMA203CD8) either alone or with nivolumab in people whose solid tumors have come back or will not respond to standard care. It may help by training the immune system to recognize and attack tumor cells that match the trial’s test requirements.
Stanford, CaliforniaAges 18 years+ - NCT03683251RecruitingPhase 3
Extension study for a refillable eye implant plus ranibizumab
This trial studies whether continuing treatment with a refillable eye implant (Port Delivery System) and ranibizumab injection helps control a specific type of wet macular degeneration. It’s mainly for people who already finished an earlier related study and are able to keep up with frequent eye checks and procedures.
Phoenix, ArizonaAges 50 years+ - NCT03655912Recruiting
Video games and eye therapy for lazy eye
This study tests whether binocular (two-eye) visual therapy using video games can improve “lazy eye” vision. It’s aimed at people with certain types of lazy eye and who have not had previous amblyopia treatment.
Monterrey, Nuevo LeónAges 4–10 - NCT03653650Recruiting
Platelet-rich plasma for stubborn corneal surface wounds
This trial studies injecting your own platelet-rich plasma into the eye to help a persistent corneal surface defect heal. It may help if you have a recurring or nerve-related corneal ulcer, but it’s not for certain ulcer types or active eye infections.
Monterrey, Nuevo LeónAges Any age - NCT03666052Enrolling by invitation
Study for kids with severe nearsightedness in Shanghai
This study registers children and teens in Shanghai who have significant nearsightedness, to better track eye health over time. It may help researchers understand why high myopia develops and how to prevent or monitor complications.
Shanghai, Shanghai MunicipalityAges 4–18 - NCT03680794Recruiting
Testing a blood and eye-fluid marker in retinal disease
This study looks at a specific lab marker (sCD160) in blood and eye fluids to see how it relates to poor blood flow in the retina. You may be asked for samples taken during eye surgery to help doctors understand the disease better.
ReimsAges 18 years+ - NCT03546387Recruiting
Anesthesia and brain thinking changes in children with retinoblastoma
This study looks at whether having anesthesia more than once (for eye/surgery treatment) affects children’s thinking and learning. It may help doctors plan safer care and better follow-up for children with retinoblastoma.
New York, New YorkAges 6–17 - NCT03714503Recruiting
Head positioning after retinal detachment surgery
This study looks at whether a specific head position after retinal detachment repair affects healing. It may help patients learn a safer, more effective way to position their head while recovering.
Prairie Village, KansasAges 18 years+ - NCT03694626Recruiting
Test a light-response study to measure and track light sensitivity
This study aims to objectively measure how your pupils respond to light and how your eye muscles react using recording tests. It may help confirm the cause of light sensitivity (especially after a brain injury) and better track how it responds to care.
Iowa City, IowaAges 18–80 - NCT03577041Recruiting
Cost study of eye injections for new macular degeneration
This study evaluates the cost-effectiveness of three anti-VEGF eye injection treatments (bevacizumab, ranibizumab, or aflibercept) for patients with newly diagnosed age-related macular degeneration affecting the center of vision. The research aims to understand which treatment option provides the best medical and financial value in France.
AmiensAges 18–70 - NCT03708627RecruitingEarly Phase 1
Bimatoprost for eye swelling in Graves’ orbitopathy
This early study tests whether bimatoprost (eye drops) can reduce signs of Graves’ orbitopathy, a condition that can cause bulging eyes. It may help improve eye symptoms for people whose Graves-related eye problems are present.
Seattle, WashingtonAges 18 years+ - NCT03662776Enrolling by invitation
How past eye-cancer treatment affects survivors’ well-being
This study looks at how different treatments for one affected eye retinoblastoma may affect survivors’ emotional and social functioning. It may help doctors understand which treatment approaches are linked with better day-to-day well-being over time.
New York, New YorkAges 8–17 - NCT03298737Enrolling by invitation
Study of visual attention and eye movement patterns
This study looks at how your eyes move and how you pay attention to what you see. It may help researchers understand normal eye and attention patterns and how they work.
Rochester, New YorkAges 18–65 - NCT03381794Recruiting
Cornea transplant registry for patients in Germany
This trial is not testing a new treatment. It collects and organizes information about people in Germany who have had a corneal (front-of-eye) transplant since 2001 to help future care and research.
Homburg, SaarlandAges 1–100 - NCT03475173Recruiting
Non-invasive eye scans for healthy and specific retinal problems
This study tests new, non-invasive ways to measure how the retina (the light-sensing part of the eye) is structured and how well it works. It may help researchers better understand certain vision disorders and how to track them, without surgery or injections.
Iowa City, IowaAges 18–99 - NCT03403686Recruiting
Study eye treatment target for diabetic retinopathy
This study tests a new approach aimed at improving diabetic eye disease (diabetic retinopathy). It may help by changing inflammation and related processes in the eye, especially in people who have diabetes and eye changes.
Birmingham, AlabamaAges 21–98 - NCT03399175Recruiting
Early immune-suppressing treatment for VKH eye disease
This trial studies giving immune-suppressing treatment early in Vogt-Koyanagi-Harada (VKH) disease to see if it improves outcomes. It may help people reduce ongoing eye inflammation if they qualify and can be followed for a longer time.
São Paulo, São PauloAges 10–70 - NCT03299530Recruiting
Testing how corneal astigmatism measures on different settings
This study checks how accurately eye measurements describe astigmatism (a focus-bending problem) using different exam modes. It may help improve how doctors assess astigmatism after cataract surgery so treatment planning is more precise.
Wenzhou, ZhejiangAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.