Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07618364Recruiting
Rinsing to reduce eye inflammation in dry eye disease
This study tests whether rinsing the eye surface helps reduce inflammation and symptoms in people with dry eyes. Participants must have a specific inflammatory marker (MMP-9) in both eyes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07623252Recruiting
Testing new diagnostic criteria for optic nerve inflammation
This study evaluates new guidelines for diagnosing optic neuritis, a condition where the nerve that carries vision becomes inflamed. If you have sudden vision loss in one or both eyes and your doctor thinks optic neuritis might be the cause, this trial will help confirm the diagnosis using updated diagnostic criteria.
Nanning, GuangxiAges Any age - NCT07623382RecruitingEarly Phase 1
Stem Cell Treatment for Dry Eye Disease
This early-stage trial tests whether special cells derived from umbilical cord tissue can help treat dry eye disease. The treatment uses tiny particles called extracellular vesicles that may reduce eye dryness and improve comfort.
Xiamen, ChinaAges 18 years+ - NCT07627698RecruitingPhase 1/Phase 2
CAR-NK Cell Therapy for Advanced Melanoma
This trial tests engineered immune cells (CAR-NK cells) designed to target two markers found on melanoma cells. The goal is to help patients with melanoma that has spread or cannot be surgically removed and has not responded to or is unsuitable for standard treatments.
Shenzhen, GuangdongAges 18–75 - NCT07628946Recruiting
Eye Disease Database Study with Advanced Imaging
This study is building a detailed database of images and information from people with various eye diseases, especially those involving inflammation or swelling. Researchers will use advanced cameras and tests to better understand these conditions and potentially improve treatments.
BeijingAges 3 years+ - NCT07629557RecruitingPhase 4
Same-Day Corneal Cross-Linking for Keratoconus in Both Eyes
This study tests a same-day procedure that strengthens the cornea (the clear front part of the eye) in both eyes using a special light treatment, called cross-linking. It may help slow or stop the progression of keratoconus, a condition where the cornea becomes cone-shaped and causes blurry vision.
Westerville, OhioAges 13 years+ - NCT07633457Recruiting
Comparing two surgical techniques for macular hole repair
This pilot study compares two surgical approaches to close a specific type of eye hole in the macula (the part of the retina responsible for sharp vision). The trial tests whether using tissue from your eye's outer layer works as well as using a membrane from inside the eye.
Cairo, AbbassiaAges Any age - NCT07634913Recruiting
Mobile App for Eye Disease Detection
This study tests a smartphone-based system designed to help detect diseases affecting the front of the eye. Researchers will develop and refine this mobile tool to see if it can accurately identify common eye conditions using photos taken on a phone or with standard eye-examination equipment.
Guangzhou, GuangdongAges 18 years+ - NCT07634991RecruitingPhase 4
N-acetyl Cysteine for Diabetic Eye Disease
This study tests whether a supplement called N-acetyl cysteine can help slow or improve mild to moderate diabetic eye disease (diabetic retinopathy). The goal is to see if it's safe and effective for people with type 2 diabetes.
CairoAges 18–70 - NCT07635329Recruiting
Home Vision Therapy Guided by Brain Scans
This study tests whether vision rehabilitation exercises done at home, guided by brain imaging, can help people regain vision after a stroke, brain injury, or tumor. Participants will use brain scans to personalize their therapy.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07637500Recruiting
Tiny Eye Insert to Improve Close-up Vision
This trial tests a tiny device inserted into the eye to help people aged 45–60 who have trouble seeing up close. If you have good distance vision but struggle reading or seeing near objects, this study may help you see better without glasses for reading.
HeidelbergAges 45–60 - NCT07638943Recruiting
Switching multifocal contact lenses to improve comfort
This study compares two brands of multifocal contact lenses (lenses that help you see at multiple distances) in people over 40 who are currently happy with their INFUSE One-Day Multifocal lenses. Researchers want to see if switching to DAILIES TOTAL1 Multifocal lenses provides similar or better comfort and vision.
La Jolla, CaliforniaAges 40 years+ - NCT07642960Recruiting
Fine-needle Heat Treatment Plus Eye Injection for Corneal Blood Vessel Growth
This trial tests a combination of two treatments—a heat procedure and a medication injection—to reduce abnormal blood vessel growth on the clear front surface of your eye (cornea). The goal is to improve your vision and prevent further damage.
Ho Chi Minh City, Xuan HoaAges 18 years+ - NCT07642999Recruiting
How Children's Screen Time Affects Eye Development
This study tracks how much time children spend looking at screens versus outdoor activities and how that relates to their eye health over 3 years. Researchers will give your child a special device to wear at home to measure their visual habits.
New York, New YorkAges 7–12 - NCT07648355Recruiting
Vision outcomes with Clareon TruPlus lens implants
This study tests a new type of lens implant (Clareon TruPlus) used during cataract surgery. Researchers will measure how well patients see afterward and how satisfied they are with their vision.
Saint Louis Park, MinnesotaAges 18 years+ - NCT07650708RecruitingPhase 4
Eye Dryness After LASIK Surgery With a New Dry Eye Treatment
This study tests whether a new eye lubricant called Miebo, given before LASIK vision correction surgery, reduces dry eye symptoms afterward. If you have mild-to-moderate dry eyes and need LASIK, this trial may help you stay more comfortable during your recovery.
Bozeman, MontanaAges 18 years+ - NCT07653074Recruiting
Vision and quality of life in youth with myopia or CVI
This study looks at how vision problems like nearsightedness (myopia) and a brain-based vision condition (CVI) affect daily life and well-being in children. It aims to understand what support they might need to thrive in a modern world.
ÖrebroAges Up to 17 years - NCT07653269Recruiting
Tracking eye changes to predict AMD progression
This study uses eye imaging and other tests to predict if early age-related macular degeneration (AMD) will progress to a more advanced stage. It aims to help doctors identify who might need closer monitoring in the future.
SingaporeAges 55 years+ - NCT07653984Recruiting
Study on immune diseases in women of childbearing age
This study follows women with certain immune disorders affecting the nervous system (like multiple sclerosis or myasthenia gravis) to understand how these conditions affect reproduction. Healthy women planning pregnancy are also included for comparison.
Guangzhou, GuangdongAges 20–55 - NCT07656688RecruitingPhase 2
Finding the best dose for a dry eye treatment
This trial tests different doses of a new eye drop (HUC1-394) to see which dose works best for people with moderate to severe dry eye disease. You may qualify if your dry eye symptoms have lasted at least 3 months and you have low tear production along with other signs of dry eye.
SeoulAges 19 years+ - NCT07657858Recruiting
Does Dry Eye Treatment Affect Astigmatism Measurements Before Cataract Surgery?
This study checks whether treating dry eyes before cataract surgery can change the way your eye's shape (astigmatism) is measured. It may help make your surgery more accurate.
Shanghai, Shanghai MunicipalityAges Any age - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Beverly Hills, CaliforniaAges 18 years+ - NCT07662603Recruiting
Breathing exercise program for teens with Behcet's after lung surgery
This trial is for teenagers with Behcet's disease who have had a specific lung surgery to remove a clot. It tests a breathing exercise program to help improve lung function after surgery.
Giza, DokkiAges 13–17 - NCT07662759RecruitingPhase 3
Study of TFC-003 for open-angle glaucoma or high eye pressure
This trial tests a new eye drop combination (TFC-003) to lower eye pressure in people with primary open-angle glaucoma or ocular hypertension. It compares the new drug to existing treatments to see if it works better or is safer.
SeongnamAges 19 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.