Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07555574Recruiting
New imaging technology to see retinal structures clearly
This research study tests a new camera technology that takes detailed pictures of the back of your eye (retina) to better understand eye diseases. Researchers want to compare images from people with eye conditions like diabetes-related eye disease, glaucoma, or age-related macular degeneration with healthy volunteers to see how the new imaging works.
Melbourne, VictoriaAges 18 years+ - NCT07556133Recruiting
Comparing two sedation medicines during cataract surgery
This study tests two sedation medicines (dexmedetomidine and propofol) used to keep patients calm and comfortable during cataract surgery. Researchers want to see which combination works best and is safest for this common procedure.
BeirutAges 18 years+ - NCT07556406Recruiting
Eye imaging study for age-related macular degeneration
This study uses specialized eye imaging to track changes in geographic atrophy, a type of vision loss from macular degeneration. Researchers will use new imaging techniques to better understand how this condition progresses and how treatments work.
San Francisco, CaliforniaAges 55 years+ - NCT07566806Recruiting
Cord Plasma Eye Drops for Nerve Pain in the Eye
This trial tests whether special eye drops made from cord plasma (a blood product) can reduce chronic eye pain caused by damaged nerves in the cornea (the clear front part of your eye). You may qualify if you have had eye pain for at least 3 months without obvious surface damage.
Singapore, SingaporeAges 21 years+ - NCT07566975Recruiting
How VEVYE Helps Dry Eye in Neuro-Eye Patients
This study tracks whether VEVYE®, a prescription eye drop, reduces dry eye symptoms and signs in people who have both a neuro-ophthalmic condition (a nerve or brain issue affecting the eyes) and dry eye disease. You'll visit the clinic for 6 months and answer questions about your eye comfort.
Houston, TexasAges 18 years+ - NCT07570212Recruiting
Personalized Brain Stimulation for Parkinson's and Similar Disorders
This study tests whether customized transcranial magnetic stimulation (a non-invasive technique that uses magnetic pulses to stimulate brain activity) can help improve symptoms in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The treatment is tailored to each person's brain activity patterns.
Beijing, Beijing MunicipalityAges 30–80 - NCT07577219Recruiting
Vision Training With Feedback for Central Vision Loss
This study teaches people with central vision loss (blurred or missing spots in the middle of vision) how to use their remaining side vision better, using special training with audio and visual feedback. It may help improve how well you can read and recognize faces.
Boston, MassachusettsAges 14 years+ - NCT07579130Recruiting
Measuring tear film thickness in dry eye disease
This study compares different ways of measuring the tear film layer (the oily coating on your eye) in people with dry eye disease. Understanding these measurements better may help doctors diagnose and treat dry eye more effectively.
Bloomington, IndianaAges 18–100 - NCT07580014Recruiting
Eye Imaging Study for Glaucoma and Narrow Angles
This study uses advanced eye imaging (OCT and OCTA) to understand how the blood vessels and tissue layers in the back of the eye differ between people with glaucoma, people at risk for angle-closure glaucoma, and people with healthy eyes. The findings may help doctors better diagnose and understand these eye conditions.
Guangzhou, GuangdongAges 18–90 - NCT07580040Recruiting
How Smoking Affects the Eyes in the Short Term
This study measures how cigarette smoking immediately affects your eyes' health and structure. Researchers compare current smokers to people who have never smoked to understand if smoking causes quick changes to the eye's surface and shape.
IstanbulAges 18–60 - NCT07586787Recruiting
Early Vitrectomy vs Laser for Early Diabetic Eye Disease
This trial compares two treatments for early diabetic retinopathy—a condition where high blood sugar damages blood vessels in the eye. Researchers want to see if removing fluid from inside the eye (vitrectomy) works better than laser treatment to prevent vision loss.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07586982Recruiting
Testing New Bifocal Toric Contact Lenses for Astigmatism
This study evaluates how well new bifocal contact lenses work for people over 40 who have astigmatism (blurred vision at all distances) and need reading help. You'll wear the lenses daily for about a month and share feedback via text message to help researchers understand comfort and vision quality.
Memphis, TennesseeAges 18–40 - NCT07588100RecruitingPhase 1
Safety study of RO7663498 eye injection for diabetic retinopathy
This is an early-stage safety study testing a new medicine injected directly into the eye to treat diabetic retinopathy (damage to blood vessels in the retina caused by diabetes). The study checks if the medicine is safe and how the body processes it.
Glendale, CaliforniaAges 18 years+ - NCT07588152RecruitingPhase 4
How Netarsudil Eye Drops Affect the Eye's Drain System
This study uses special imaging to see how the eye-pressure-lowering medication netarsudil (Rhopressa) works on the part of your eye that drains fluid. Researchers want to understand whether it helps restore normal drainage in people with high eye pressure or glaucoma.
Bloomington, IndianaAges 18 years+ - NCT07593404Recruiting
Testing a New Eye Drop for Dry Eye Disease
This study tests a new lubricating eye drop designed to relieve dry eye symptoms. If you have dry eye disease, this trial may help determine if the new formula works better than what's currently available.
Waterloo, OntarioAges 18 years+ - NCT07593885Recruiting
Artelac Complete versus VISMED MULTI for severe dry eye
This study compares two preservative-free eye drops designed to treat moderate to severe dry eye disease. It evaluates which product works better and is safer for people whose dry eyes are caused by conditions like Sjögren's disease, autoimmune blistering disorders, or damaged tear glands.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT07599241Recruiting
Exercise Program for Older Women With Thyroid, Eye, and Liver Conditions
This study tests whether a physical activity program can help older women manage three common conditions together: an underactive thyroid, high eye pressure (glaucoma), and fatty liver disease. Researchers want to see if exercise improves symptoms and overall health when addressing multiple conditions at once.
Dokki, Giza GovernorateAges 65–75 - NCT07605221Recruiting
Testing a formula for laser eye surgery astigmatism correction
This study develops a formula to help surgeons correct astigmatism (blurred vision from curved corneas) during a laser eye surgery called LASEK. If you're eligible, your surgery may be more precisely tailored to your eye shape.
Tianjin, Tianjin MunicipalityAges 18–45 - NCT07605572Recruiting
GLP-1 drugs and dry eye disease in type 2 diabetes
This study tests whether a diabetes and weight-loss medication called GLP-1 receptor agonists affects dry eye disease. Researchers want to see if this medication helps or worsens dry eyes in people with type 2 diabetes and obesity.
AthensAges 18 years+ - NCT07606300Recruiting
Light Training to Help Light Sensitivity After Head Injury
This trial tests whether a training program using colored light targets can help reduce light sensitivity (photophobia) that some people experience after a traumatic brain injury. The training involves focusing your eyes on lights during several visits.
Columbus, OhioAges 18–80 - NCT07606404Recruiting
Comparing surgical techniques for macular hole repair
This study compares ten different surgical methods for repairing full-thickness macular holes—small breaks in the central part of the retina that blur vision. You'd be in the study to help doctors learn which technique works best at restoring sight.
Almaty, AlmatyAges 18 years+ - NCT07606625RecruitingPhase 4
Nasal spray for dry eye disease and tear film stability
This study tests whether a nasal spray can improve dry eye symptoms and tear production in people with mild to moderate meibomian gland dysfunction (a common cause of dry eye). You'll use the spray daily while the research team monitors your eye health and comfort over several weeks.
Berkeley, CaliforniaAges 18 years+ - NCT07609186Recruiting
Sound therapy during cataract surgery in older adults
This study tests whether listening to special binaural sounds (through earphones) during cataract surgery helps older patients stay calm and comfortable. The surgery uses light sedation, and researchers want to see if the sounds improve the experience.
SeoulAges 65 years+ - NCT07613580Recruiting
Testing a new eye-vision recording tool in Portugal
This study compares two ways of recording eye vision test results: traditional paper methods versus a new electronic app called Acuvera Capture. You'll have your vision tested once using both methods to help researchers understand if the new tool works just as well as paper recording.
CoimbraAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.