Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07668804RecruitingPhase 1/Phase 2
Study of an eye implant for geographic atrophy from dry AMD
This trial is testing a new eye implant (TO-O-1007) to see if it's safe and helps slow vision loss from geographic atrophy, a late stage of dry age-related macular degeneration (AMD). The implant is placed inside the eye and releases medicine over time.
Hurstville, New South Wales (nsw)Ages 50 years+ - NCT07660640Enrolling by invitation
Long-term follow-up for VOY-101 eye injection study
This study follows up with people who already received the VOY-101 injection for a type of age-related vision loss (non-neovascular age-related macular degeneration) in an earlier study. It checks how they are doing over a longer period of time.
Boston, MassachusettsAges 50 years+ - NCT07636876Enrolling by invitation
Italian MS and Related Disorders Patient Registry
This is a registry study that collects health information from people with multiple sclerosis and related conditions. By joining, you help researchers better understand these diseases and improve future treatments.
Genova, GenovaAges Any age - NCT07624929Enrolling by invitation
Virtual Reality to Reduce Anxiety During Varicose Vein Treatment
This study tests whether wearing a virtual reality headset during varicose vein treatment (a minimally invasive laser procedure on your legs) can help reduce anxiety and pain. You'd use VR while the doctor treats the problematic veins under local anesthesia.
BydgoszczAges 18 years+ - NCT07589894Enrolling by invitation
Vision outcomes after cataract surgery with TruPlus lenses
This study measures how well people see after cataract removal surgery using a special TruPlus intraocular lens (an artificial lens placed in the eye). Researchers want to understand if this lens helps patients see clearly at distance with minimal side effects.
Encino, CaliforniaAges 50–80 - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT07559292Enrolling by invitation
AI screening to catch diabetes eye problems early
This study tests whether artificial intelligence can help detect early signs of diabetes-related eye damage before vision loss happens. You'd be screened at your regular doctor visit using a new AI tool, which could catch problems earlier than usual.
Madison, WisconsinAges 22 years+ - NCT07553455Enrolling by invitationPhase 4
Vevye plus Flarex eye drops for moderate to severe dry eye
This study tests a combination of two eye drop medications (Vevye and Flarex) to see if they work better together for treating moderate to severe dry eye. If you have persistent dry eye that hasn't improved with other treatments, this trial might help you and advance treatment options.
Azusa, CaliforniaAges 18 years+ - NCT07544290Enrolling by invitation
Autoimmune Hyperthyroidism Study in Young Children
This study looks at children with autoimmune hyperthyroidism (an overactive thyroid caused by the immune system attacking the thyroid gland). Researchers want to understand this condition better in children before puberty to help improve care.
Milan, ItalyAges 2–18 - NCT07529041Enrolling by invitation
Sound cues to help eyes stay still during eye exams
This study tests whether audio feedback (beeping sounds) can help people keep their eyes steady during eye imaging tests. If your eyes move around during exams, this technology might help you stay focused and get better-quality images for diagnosis.
GöttingenAges 18 years+ - NCT07514039Enrolling by invitation
Special Myopia Glasses for Children and Teens
This study tests new glasses with special microscopic patterns designed to slow down myopia (nearsightedness) in children and teenagers. Researchers want to see if wearing these glasses can help prevent myopia from getting worse.
ShanghaiAges 6–14 - NCT07503886RecruitingPhase 2
Study of an eye drop for dry eye disease
This trial tests a new eye drop called DFL24498 to see if it helps people with dry eye disease. You may qualify if your dry eye is moderate to severe and other treatments haven't worked well for you.
Chandler, ArizonaAges 18 years+ - NCT07480343Enrolling by invitation
Five-year follow-up after CREST glaucoma study
This study follows up with people who finished the CREST study to check how their eyes are doing 5 years later. It looks at the long-term results of a prior glaucoma treatment.
Newport Beach, CaliforniaAges Any age - NCT07456826Enrolling by invitationPhase 4
Comparing two eye numbing gels for shots
This trial tests a new eye-numbing gel against the standard numbing method to see which works better for patients getting regular anti-VEGF injections in the eye.
Tyler, TexasAges 18 years+ - NCT07388069Enrolling by invitationPhase 1/Phase 2
TN-001 eyedrops for progressive keratoconus
This trial tests a new eyedrop (TN-001) for people with keratoconus that is getting worse. The drops are applied twice a day to try to stop the cornea from thinning and bulging further.
Brisbane, QueenslandAges 18–40 - NCT07378891Enrolling by invitation
AI eye screening for early diabetic retinopathy
This study uses artificial intelligence (AI) to look at photos of the back of your eye (retina) to find early signs of diabetic eye disease. It aims to catch problems before they worsen, so you can get treatment sooner.
TübingenAges 18–80 - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07332988Enrolling by invitation
Light therapy for dry eyes in Graves' disease
This trial tests if low-level light therapy can improve dry eye symptoms in people with Graves' disease whose dry eyes haven't gotten better with standard treatments like artificial tears.
Iași, IaşiAges 18 years+ - NCT07327242Enrolling by invitation
AI tool to improve eye test accuracy in glaucoma patients
This trial tests if a large language model tool can help patients perform more reliable visual field tests. It may improve detection of glaucoma progression.
Palo Alto, CaliforniaAges 18 years+ - NCT07317661Enrolling by invitation
LLM-based app for cataract lens choice education
This trial studies whether a large language model (an AI tool) can help explain intraocular lens options to patients before cataract surgery. If you're planning your first cataract surgery, you may be able to join.
Palo Alto, CaliforniaAges 18 years+ - NCT07284147Enrolling by invitation
3D designed defocus lenses for slowing myopia in children
This trial tests special glasses with 3D defocus lenses to slow down the progression of myopia (nearsightedness) in children and teens. It aims to see if these lenses are more effective than standard glasses at preventing vision from getting worse.
ShanghaiAges 6–14 - NCT07268599Enrolling by invitation
Acoltremon for moderate-to-severe dry eye relief
This study tests a new eye drop called Acoltremon to see if it can relieve symptoms of moderate-to-severe dry eye disease. It may be a good option if you have had dry eye for at least 6 months and use artificial tears.
Encino, CaliforniaAges 18–60 - NCT07265024Enrolling by invitation
Exercise study for university students with vision loss
This study tests whether a traditional exercise program can improve health and well-being in university students who are visually impaired. It may help you if you can walk independently and don't have serious health issues.
Changchun, JilinAges 18 years+ - NCT07246915Enrolling by invitation
Long-Term Safety of an Eye Drop for Mild to Moderate Cataract
This is a long-term follow-up study to check the safety and effectiveness of an eye drop (REVISYON SDS100) for people with mild to moderate cataract. It is only open to people who already completed the first study for this drop.
BucharestAges 40 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.