Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT06638944RecruitingPhase 2
Wearable feedback device for swallowing therapy in stroke or Parkinson's
This study tests a wearable device that provides feedback to help improve swallowing in people with stroke or Parkinson's disease. It may help make swallowing therapy more effective by showing real-time progress during exercises.
Champaign, IllinoisAges 50–90 - NCT06855537RecruitingPhase 4
Treating unstable plaques that are not fully blocked
This trial compares treatments for heart patients who have a dangerous, but not fully blocking, fatty plaque in their arteries. It aims to see if treating these plaques with a stent or balloon can prevent future heart problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT07287436Recruiting
Watchman device to prevent stroke in atrial fibrillation
This trial tests a device called the WATCHMAN Elite, which is placed in a small pouch of the heart to close it and reduce stroke risk, potentially allowing patients to stop blood thinners. It is for people with atrial fibrillation who cannot or prefer not to take long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT07878546Recruiting
Hemorrhoid surgery: Ligasure versus conventional diathermy
This study compares two surgical tools used to remove hemorrhoids: Ligasure, which seals blood vessels with heat and pressure, and conventional diathermy, which uses heat to cut and stop bleeding. The goal is to see which method helps patients recover better with less pain.
SohagAges Any age - NCT07238556Recruiting
Digital exercise program for cardiovascular risk
This study tests a new digital tool that helps clinicians prescribe personalized exercise plans to patients with cardiovascular risk factors like high blood pressure, diabetes, or obesity. Participation involves using the tool and following an exercise plan for a few months to see if it improves health.
Farmington, ConnecticutAges 18–64 - NCT07095634Recruiting
Heart risk study for Crohn's and colitis patients
This study looks at heart health in people with Crohn's disease or ulcerative colitis. It aims to understand the risk of heart problems over 2 years.
San Donato Milanese, MilanAges 16 years+ - NCT07877480Recruiting
Predicting high-risk carotid plaque with imaging and biomechanics
This study looks at using scans and computer models to better predict which carotid artery plaques are dangerous, which may help guide safer treatment decisions.
MilanAges 18 years+ - NCT07706712Recruiting
Study of a new system for treating ventricular tachycardia
This study tests a new device called the DuoVT PFA System to treat ventricular tachycardia, a fast heart rhythm that can be dangerous. It aims to help people who have this condition along with heart disease from a past heart attack, and who have not been helped by medications.
Split, DalmtiaAges 18–80 - NCT07877324Recruiting
Imaging heart artery inflammation with a new tracer
This study uses a special PET/CT scan to look for inflammation in the artery walls of the heart. It will help doctors understand how inflammation relates to coronary artery disease and recent heart attacks.
TurkuAges 50–80 - NCT06297291Recruiting
Blood pressure study after kidney nerve treatment
This study looks at how well a procedure that uses sound waves to calm kidney nerves (renal denervation) lowers blood pressure over time. It may help people whose blood pressure stays high despite taking medication.
Long Beach, CaliforniaAges 18 years+ - NCT06220773RecruitingPhase 3
combination treatment for type 2 diabetes and high blood pressure
This study tests two new combination medicines for people who have both type 2 diabetes and high blood pressure. It looks at how well they work and how safe they are. Participants stop their current diabetes and blood pressure drugs during the trial, except for the diabetes drug metformin.
Jakarta, DKI JakartaAges 19 years+ - NCT07877948Recruiting
Combination therapy for diabetic nerve pain and foot ulcers
This study tests whether a treatment called Bionerv E+ helps with nerve pain and healing of foot ulcers in people with type 2 diabetes, compared with a standard vitamin B complex. If you have diabetes-related nerve damage and a foot ulcer that is not too severe, this study might help you understand if this new option works.
Cheras, Kuala LumpurAges 18 years+ - NCT07874763Recruiting
Comparing two pacing lead locations for heart devices
This study compares two places to attach the pacing wire (lead) that helps your heart beat regularly. The goal is to find out which location works better for people getting a new pacemaker or similar heart device.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07878325Recruiting
Specialized heart and diabetes clinic for people with type 2 diabetes
This trial tests a specialized clinic that combines diabetes and heart care for people with type 2 diabetes who also have heart or blood vessel problems. The clinic will also check for unrecognized heart failure to improve overall health.
SvendborgAges 18 years+ - NCT07852338RecruitingPhase 3
Placental graft for diabetic foot ulcers
This trial tests a treatment made from placental tissue, called Bioxheal, which is placed on a diabetic foot ulcer to help it heal. It compares this treatment to standard care alone.
Boardman, OhioAges 18 years+ - NCT07878767Recruiting
Sound waves for varicose veins in the legs
This study tests a new treatment that uses sound waves to close off varicose veins in the legs, without surgery. It may be an option for people with mild to moderate varicose veins who are looking for a less invasive treatment.
Câmpina, PrahovaAges 35–80 - NCT06075823Recruiting
Mitral valve repair for heart failure with ATTR amyloidosis
This trial tests a clip procedure to fix a leaky heart valve in people who also have a heart condition called ATTR-CM, which can cause heart failure. The clip is placed without open-heart surgery to help improve symptoms and quality of life.
GrazAges 18 years+ - NCT07877519Recruiting
Sedation options for pulsed field ablation in atrial fibrillation
This study compares two ways to keep patients comfortable during a procedure called pulsed field ablation for atrial fibrillation: conscious sedation (you're awake but relaxed) versus general anesthesia (you're fully asleep). The goal is to find which method works better and is safer for patients.
Beijing, Beijing MunicipalityAges 18–80 - NCT06280820Enrolling by invitation
A study of heart failure patterns (MAP-HEART)
This study looks at different types of heart failure to understand them better. You may join if you have active heart failure (with symptoms like shortness of breath or swelling) and are willing to participate in research activities.
Baltimore, MarylandAges 18–100 - NCT07054073Recruiting
HCMR Re-Imaging: MRI follow-up for HCM patients
This study uses MRI scans to re-examine people with hypertrophic cardiomyopathy (a thickening of the heart muscle) who were part of the original HCMR study. It compares different types of HCM to learn more over time.
Boston, MassachusettsAges 18–65 - NCT07287423Recruiting
A study of a new pacemaker system for heart rhythm problems
This trial tests a new pacemaker system for people who need a pacemaker for a slow or irregular heartbeat. It aims to see if the system is safe and works well.
PragueAges 18 years+ - NCT07678723Recruiting
Pupil test to predict blood pressure drop during C-section
This study checks if a simple pupil light reflex test can predict a drop in blood pressure after spinal anesthesia during elective C-sections. If it works, doctors could better manage blood pressure and reduce dizziness or nausea.
DamiettaAges 18–45 - NCT07558876Recruiting
Upper limb training with vibration therapy after stroke
This trial tests whether combining task-oriented exercises with focal vibration (gentle vibrating stimulation) can help improve arm and hand function and feeling in people who've had a stroke. The vibration aims to help your brain better sense where your hand is and what it's touching.
SeoulAges 20 years+ - NCT07592273RecruitingPhase 2/Phase 3
Gene therapy for diabetic eye disease without macular swelling
This trial tests a gene therapy injection into the eye to treat diabetic retinopathy (eye damage from diabetes) before it progresses. The goal is to slow or prevent vision loss and potentially delay the need for laser treatment or other injections.
Mesa, ArizonaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.