Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,602 recruiting studies in this area right now.
By phase
- Not applicable7,631
- Phase 4471
- Phase 2468
- Phase 3436
- Phase 1349
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure535
- Hypertension388
- Cardiovascular Diseases374
- Coronary Artery Disease364
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)153
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases59
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital51
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University47
- Johns Hopkins University45
Where studies are running
- California454
- Alabama196
- Arizona180
- Massachusetts172
- New York168
- Florida139
- Texas122
- Maryland118
- Minnesota117
- Illinois113
Recruiting studies9,602 total
- NCT07792655Recruiting
Hand therapy at home after stroke
This study tests a therapy program done at home using video calls to help improve hand function after a stroke. It may help you regain better use of your hand if you had a stroke at least 6 months ago.
Ann Arbor, MichiganAges 40–75 - NCT06899750Recruiting
E3 Hypertension: A team program for blood pressure control
This study tests a team-based program to help African American and Latinx people with uncontrolled high blood pressure. You'll use a smartphone app and get extra support from a doctor team to manage your blood pressure better.
Chicago, IllinoisAges 18 years+ - NCT06280820Enrolling by invitation
A study of heart failure patterns (MAP-HEART)
This study looks at different types of heart failure to understand them better. You may join if you have active heart failure (with symptoms like shortness of breath or swelling) and are willing to participate in research activities.
Baltimore, MarylandAges 18–100 - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
Birmingham, AlabamaAges 2 days–17 years - NCT05868616Recruiting
Checking heart resynchronization timing with a noninvasive test
This trial evaluates a noninvasive way to assess who should get Cardiac Resynchronization Therapy (CRT), and to check results after implantation. If you fit the heart rhythm and heart pump criteria, the approach may help confirm whether CRT is appropriate for you.
OsloAges 18–80 - NCT07672860RecruitingPhase 2
UDCA to protect kidneys during partial nephrectomy
This clinical trial is testing whether a medicine called ursodeoxycholic acid (UDCA) can help protect the kidneys during partial nephrectomy (removing only the tumor while keeping the healthy part of the kidney). It is for people with early-stage kidney tumors who will have temporary interruption of blood flow to the kidney during surgery.
Nanjing, JiangsuAges 18–75 - NCT05733416Recruiting
FDG PET/CT scan after unexplained stroke to find hidden cancer
This study checks whether doing an intensive scan using FDG PET/CT shortly after a “cryptogenic” (unexplained) ischemic stroke can uncover an underlying cause, such as cancer. If a hidden source is found earlier, it may help guide the next treatment steps.
Calgary, AlbertaAges 18 years+ - NCT07137455Enrolling by invitation
New system to record and classify heart electrical signals
This trial is testing a new recording system that helps doctors see and classify the heart's electrical signals during a routine heart procedure. It may improve how doctors treat abnormal heart rhythms or place pacemakers.
Atlanta, GeorgiaAges 21–100 - NCT07792226Recruiting
Stomach procedure for weight loss (ESG with fundal ablation)
This study tests a new procedure called endoscopic sleeve gastroplasty with fundal mucosal ablation to help with weight loss. It is an option for people with obesity who have not had success with other methods and who have not had prior stomach surgery.
Morgantown, West VirginiaAges 18 years+ - NCT07005050Recruiting
Kidney nerve treatment for high blood pressure pilot study
This study tests a new treatment that uses a device to calm overactive nerves in the kidneys, which may help lower high blood pressure. It is for people who are already taking at least two blood pressure medications and still have high readings.
Birmingham, AlabamaAges 21–80 - NCT07690046Recruiting
Cardiac rehab after abdominal aortic aneurysm repair
This study looks at whether a supervised exercise and heart rehabilitation program helps people recover better after surgery to fix an abdominal aortic aneurysm (a bulging, weak spot in the main artery in the belly). It aims to improve heart health and overall recovery.
Innsbruck, TyrolAges 18 years+ - NCT07639853Enrolling by invitation
Doctor feedback survey on Concerto Versa coils
This study gathers feedback from doctors who use Concerto Versa detachable coils (small metal devices that help treat brain aneurysms). The survey helps improve how these coils work and are used.
Piscataway, New JerseyAges 22 years+ - NCT07676578Recruiting
Virtual reality walking rehab for recent stroke patients
This study tests if using a virtual reality headset during walking exercises can help people who had a stroke within the past 1 to 6 months improve their walking. You might be able to join if you can walk a bit but still need help or practice, and your doctor approves.
Indianapolis, IndianaAges 18 years+ - NCT06940752Enrolling by invitation
A new way to treat stubborn heart rhythm problems
This study tests a special navigation technique to improve the success of repeat catheter ablation for ventricular arrhythmias, helping patients who haven't been helped by prior procedures or medications.
Atlanta, GeorgiaAges 21–100 - NCT05490238Recruiting
Wrist vs arm access for complex heart procedures
This study compares using the wrist (radial artery) versus a different access site (conventional radial access approach) during complex, larger “bore” heart procedures to open blocked coronary arteries. It aims to see which approach is safer and works better for challenging cases like chronic blockages or heavily calcified arteries.
ArlonAges 18 years+ - NCT07835828Recruiting
Optimised heart and kidney protection for chronic kidney disease and heart disease
This study tests a new approach to protect the heart and kidneys in people with both chronic kidney disease and heart or blood vessel problems. By optimising treatment, researchers hope to reduce the risk of further kidney or heart damage.
SvendborgAges 18 years+ - NCT07318610RecruitingPhase 3
Study of a new blood thinner in people with leg artery disease
This trial tests if a new blood-thinning drug (factor XI inhibitor) can prevent serious heart and leg problems in people who recently had a leg artery procedure. It compares the new drug to standard care for up to 3 years.
Alexander City, AlabamaAges 18 years+ - NCT07643896Recruiting
Blood test for pregnancy risk assessment using fetal cells
This study tests a new blood test that looks for fetal cells in your bloodstream to check your baby's health during pregnancy. The test is non-invasive—just a regular blood draw—and aims to help identify pregnancy risks earlier than traditional methods.
Phoenix, ArizonaAges Any age - NCT07132788Recruiting
Study of pulmonary arterial hypertension and lean muscle mass
This study looks at how pulmonary arterial hypertension (PAH) affects lean muscle mass. It aims to understand the relationship between PAH and muscle loss, which could help improve treatments and quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07445087Recruiting
Takhzyro for hereditary angioedema in teenagers and adults
This study is for people in South Korea with hereditary angioedema. It looks at how well the drug Takhzyro works and how safe it is for teenagers and adults who are already using it or will start using it.
Suwon, Gyeonggi-doAges 12 years+ - NCT07825064RecruitingPhase 2
Cevostamab combination after CAR T-cell therapy for multiple myeloma
This trial tests a new drug, cevostamab, combined with two standard medicines (pomalidomide and dexamethasone) for people with multiple myeloma who have already had CAR T-cell therapy. It aims to see if this combination can help control the cancer better.
GreifswaldAges 18 years+ - NCT06604650Recruiting
Park-based health program for older adults in Miami
This study looks at how community park programs can help older adults stay healthy. It will use information already collected from people who are already part of the Miami-Dade Active Older Adults study.
Miami, FloridaAges 50–95 - NCT07089576Recruiting
Study of the Arcevo LSA device for aortic arch repair
This trial tests a new device called Arcevo LSA to treat certain types of aortic arch problems, like dissections (tears) or aneurysms (bulges). It is for people who need open surgery, and the device helps fix the left subclavian artery area.
Birmingham, AlabamaAges 18–80 - NCT05030545RecruitingPhase 4
PET/CT study of spironolactone or eplerenone in primary aldosteronism
This study looks at how primary aldosteronism affects the heart and blood vessels, and whether blocking its hormone signal (with spironolactone or eplerenone) changes those findings on imaging tests. It is small and focuses on people with confirmed or suspected primary aldosteronism who are being followed for heart health.
Boston, MassachusettsAges 18–85
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,602 recruiting cardiology studies from the U.S. registry right now, out of 14,560 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.