Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT04076449Recruiting
MRI measurements for epilepsy from a single brain blood vessel lump
This study uses special MRI scans to measure brain changes in people whose seizures are related to one cerebral cavernous malformation (a type of abnormal blood vessel in the brain). It aims to find a measurable “biomarker” from MRI that may help understand the epilepsy and the brain structure around it.
Beijing, Beijing MunicipalityAges 18–70 - NCT04078373Recruiting
Rehab study of bladder problems after recent stroke
This trial looks at urinary (bladder) problems in people who are in the early recovery phase after a stroke, while they receive inpatient rehabilitation. It may help improve how bladder issues are managed during rehab after stroke.
LjubljanaAges Any age - NCT04078243Recruiting
Trial setup and testing in adults with pulmonary hypertension
This study tests new “trial tools” and designs for running early research in people with pulmonary hypertension. If you qualify, you may be asked to do extra trial-related procedures to help researchers test the process safely and smoothly.
Sheffield, South YorkshireAges 18 years+ - NCT04080492Recruiting
Quality of life study for heart disease patients
This study asks people with certain heart conditions to complete follow-up questionnaires to better understand how their quality of life changes over time. It may help improve how care plans are made and supported for patients and their families.
Cleveland, OhioAges 18–70 - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT04084132Recruiting
Testing earlier vs later valve replacement after repaired Tetralogy
This study compares doing a valve replacement earlier versus later in people born with Tetralogy of Fallot who already had heart surgery as babies. It may help decide the safest timing to protect heart function, especially right-sided pumping and valve leakage.
AarhusAges 12 years+ - NCT04087200Recruiting
High-dose statin early after heart attack to protect kidneys
This trial looks at whether starting a high dose of a statin (cholesterol medicine) right away after an acute coronary syndrome (a serious heart condition) can reduce future heart and kidney problems. It may help patients by testing a strategy meant to prevent complications soon after the event.
PratoAges Any age - NCT04088682Recruiting
Check hospital care quality for adults with heart attacks
This trial looks at how well hospitals measure and deliver care for adults who arrive soon after a certain type of heart attack. It may help improve quality of treatment for people with acute ST-elevation myocardial infarction (a specific heart attack pattern).
Beijing, Beijing MunicipalityAges 18 years+ - NCT04097145Recruiting
Heart valve repair for severe leaking tricuspid valve
This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.
Phoenix, ArizonaAges 18 years+ - NCT04098536Recruiting
Diesel exposure study of long-lasting inflammation and blood vessels
This study exposes healthy adults to diesel fumes to see how it affects inflammation (the body’s response to irritation) and blood vessels over time. It may help researchers understand health risks from diesel air pollution, though it is not for people with existing chronic health conditions.
Athens, AtticaAges 18–60 - NCT04102930Recruiting
Study of immune and genetic features in GCA and PMR
This study looks at immune system and genetic (inherited) differences in people diagnosed with giant cell arteritis or polymyalgia rheumatica. It aims to improve understanding of why these conditions happen and how they vary between people.
Canterbury, KentAges 50 years+ - NCT04106479Recruiting
Baby heart ultrasound study in newborn congenital heart defects
This study records newborn heart measurements (using medical imaging) to compare babies with certain congenital heart defects to healthy-term babies. The goal is to see how well one test matches another, which may help doctors better understand heart conditions in newborns.
Montreal, QuebecAges birth–1 week - NCT04114994Recruiting
Memory testing study for adults 50 and older
This study checks how people’s thinking and memory change over time using a specific cognitive test. It may help researchers understand patterns of memory change and supports future research on brain health.
Miami, FloridaAges 50 years+ - NCT04114084Recruiting
Sleep apnea study in people with MGUS or multiple myeloma
This study looks at sleep apnea (breathing pauses during sleep) in people who have MGUS or multiple myeloma. You may be asked to participate because you already need a bone marrow biopsy as part of your usual care.
Iowa City, IowaAges 18–99 - NCT04115241Recruiting
Study of activity levels during bone marrow transplant
This study looks at how active people are during a bone marrow transplant. The goal is to better understand activity patterns during transplant care and recovery.
Iowa City, IowaAges 18–99 - NCT04117230Recruiting
Registry for heart support devices after severe circulation problems
This study is a registry that collects information from adults who need a temporary heart circulation support device such as VA-ECMO or an Impella pump (or newer similar devices). It may help doctors better understand which patients benefit most and how these devices are used in real life.
BaselAges 18 years+ - NCT04119544Recruiting
Mirror therapy rehab for arm after recent stroke
This trial tests whether mirror-based therapy can help improve movement in the affected hand and wrist after a stroke. It may help you regain upper-limb function when standard rehab alone isn’t enough.
Reims, Champagne-ArdenneAges 18–100 - NCT04118790Recruiting
MRI study of brain microstructure after stroke
This study uses detailed brain MRI scans to learn how brain tissue changes after stroke or a TIA (a brief stroke-like event). It may help researchers better understand brain recovery and improve future care.
Copenhagen, København NVAges 18 years+ - NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT04124120Recruiting
Single vs multiple bypass grafts for women heart surgery
This study compares outcomes of using one bypass graft versus multiple bypass grafts during coronary artery bypass surgery in women. It aims to see which approach leads to better recovery and heart outcomes for eligible patients.
Los Angeles, CaliforniaAges 18 years+ - NCT04126148Recruiting
Breathing test to measure heart oxygen use
This study measures how well the heart uses oxygen during a breathing-based test. It aims to validate a way to assess heart blood flow in people with suspected or known coronary artery disease, using special heart imaging and a heart blood-flow measurement during an angiogram.
Montreal, QuebecAges 18 years+ - NCT04124848Recruiting
Sleep apnea study for Somali community adults
This study looks at obstructive sleep apnea—breathing pauses or poor breathing during sleep—in Somali community members. It aims to learn more about sleep apnea in this specific group, which can help guide better care.
Rochester, MinnesotaAges 18 years+ - NCT04126785Recruiting
Exercise program for older adults with controlled high blood pressure
This trial compares two types of water-based exercise—short, intense bursts versus a steady, moderate pace—in older adults with high blood pressure that is already being controlled. It may help determine which exercise style lowers blood pressure and is easier or safer to stick with.
Bauru, São PauloAges 60 years+ - NCT04130269Recruiting
Study of stress, anxiety, and pain after heart attack
This study looks at how anxiety, stress, and pain may affect people after a heart attack. It may help researchers understand who could benefit from supportive strategies after myocardial infarction (heart attack).
Graz, StyriaAges 19–90
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.