Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07501234Recruiting
Study of the MitraFix® mitral valve repair system
This trial tests a new catheter-based device to fix a leaky mitral valve without open-heart surgery. It is for people whose severe mitral regurgitation puts them at high risk for traditional surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07503236Recruiting
Study of a new device for leaking heart valves
This trial tests a new device designed to fix a leaky mitral valve in people with heart failure. It may help you breathe easier and feel less tired if your valve leak is severe and medicines have not been enough.
Sacramento, CaliforniaAges 21 years+ - NCT07501299Recruiting
HeartBeam ECG Registry for heart monitoring
This registry collects ECG data from people who are already getting an ECG for their heart health. It uses a device called HeartBeam to see if it works as well as the standard ECG machine.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07502599Recruiting
Fainting detection and early warning in syncope study
This study tests a new way to detect and warn about fainting in people with certain types of syncope (temporary loss of consciousness). It may help those who have already had a specific fainting evaluation called an ARS assessment.
Rochester, MinnesotaAges 18 years+ - NCT06491693Recruiting
Can eye nerve test predict brain complications after carotid surgery?
This trial checks if measuring the nerve sheath in your eye can help doctors predict brain-related problems after carotid artery surgery. It aims to improve safety during the procedure.
IstanbulAges 50–80 - NCT06764797RecruitingPhase 3
Virtual reality and brain stimulation for arm recovery after stroke
This trial tests whether combining virtual reality mirror therapy with a gentle brain stimulation technique can improve arm and hand movement in people who have had a stroke. It may be an option if you have moderate to severe arm weakness and it has been more than three months since your stroke.
Riyadh, Riyadh RegionAges 18 years+ - NCT07505199RecruitingPhase 1
Immune cell therapy for advanced heart failure from blocked arteries
This early-phase study tests a new type of immune cell therapy (CAR-DC) for people with advanced heart failure due to blocked arteries. It aims to see if the treatment is safe and may help improve heart function.
Hangzhou, Zhejiang / 浙江Ages 18–75 - NCT07506174Recruiting
Pelvic PNF and trunk training for stroke recovery
This trial tests whether combining pelvic PNF (a therapy that uses specific patterns to improve movement) with trunk training can help people with chronic stroke walk better and improve balance.
Lahore, Punjab ProvinceAges 40–75 - NCT07500610Recruiting
How inflammation affects heart and mobility in PAD
This study looks at how inflammation affects people with peripheral artery disease (PAD), and how it relates to heart health and walking ability. The goal is to understand these connections better, which could help doctors treat PAD more effectively.
Vancouver, British ColumbiaAges 19 years+ - NCT07506499Recruiting
Cardiac Rehab for Hospitalized Heart Failure Patients
This study tests whether a cardiac rehabilitation program (a supervised exercise and education plan) helps people recovering in the hospital from severe heart failure. It is for those aged 45–65 whose heart pumps less than 40% of its normal amount.
Banī Suwayf, Beni-Suef GovernorateAges 45–65 - NCT07503301Enrolling by invitation
Study on stroke recovery and limb therapy
This trial tests if a limb therapy called RIC can help people recover from a stroke caused by small vessel disease. It is designed for people aged 50-65 who have had a recent stroke and have few other health issues.
Hangzhou, ZhejiangAges 50–65 - NCT07507201RecruitingEarly Phase 1
Car-T cells for autoimmune diseases like lupus
This trial tests whether specially-engineered immune cells (CAR-T cells) can help people with certain autoimmune diseases that haven't gotten better with standard treatments. The cells are designed to target and remove faulty B cells that are causing the immune system to attack the body.
Hangzhou, ZhejiangAges 3 years+ - NCT07499401Recruiting
Fluid response test in ICU patients with vein congestion
This study looks at how tiny blood vessels respond to extra fluids in ICU patients who have vein congestion. It helps doctors understand if giving more fluid is helpful or harmful for you.
Ancona, ItalyAges 18 years+ - NCT07498764Enrolling by invitation
Virtual care after cardiac arrest recovery program
This trial tests a virtual care program to help people recover after cardiac arrest. It offers follow-up support through video or phone sessions.
Basildon, EssexAges 18 years+ - NCT07503834RecruitingPhase 1/Phase 2
Anakinra to prevent blood clots in kidney transplant patients
This trial tests whether a medicine called anakinra, which reduces inflammation, can prevent blood clots forming in the kidney after a transplant. It may help improve the chances of the new kidney working well.
NantesAges 18 years+ - NCT07500324Recruiting
Searching for new markers in age-related eye diseases
This study looks for proteins in the blood and eye fluids that may help doctors better understand and monitor three common eye conditions: age-related macular degeneration, diabetic retinopathy, and retinal detachment. If you have one of these conditions, or if you are a healthy control with no retinal disease, you may be able to help by giving a small sample of blood or fluid from your eye during a routine procedure.
Roma, ItalyAges 18 years+ - NCT07501923Recruiting
How heat exposure day and night affects human health
This study looks at how exposure to heat during the day, night, or both affects the health of healthy young adults. It may help understand how heat impacts the body and find ways to protect people from heat-related risks.
Hefei, AnhuiAges 18–30 - NCT07501533RecruitingPhase 2
Insulin timing for severe stroke patients with high blood sugar
This study compares giving insulin early versus waiting a bit to lower blood sugar after a severe stroke. It may help understand the best timing to treat high blood sugar in this situation.
Wuhu, AnhuiAges 18 years+ - NCT07500519Recruiting
Shock Indexes and Low Blood Pressure After Spinal for Cesarean
This study looks at whether certain simple measurements (called shock indexes) taken before your cesarean delivery can help predict if you might have a drop in blood pressure after you get spinal anesthesia. The goal is to help doctors take better care of moms like you during the surgery.
IstanbulAges 18 years+ - NCT07506382Recruiting
Comparing two self-expanding aortic valves in TAVR
This study compares two types of self-expanding aortic valves used during a minimally invasive procedure called TAVR. It aims to see which type works better in everyday practice.
Montpellier, OccitanieAges 18 years+ - NCT07500116Recruiting
Home monitoring after minor stroke or TIA
This study tests whether using a wearable and smartphone app at home can help monitor recovery after a minor stroke or mini-stroke (TIA) – possibly reducing hospital stays while keeping you safe. If you have mild symptoms that stabilized in the ER, and you have help at home, you may qualify.
BarcelonaAges Any age - NCT07499947Recruiting
Predicting low blood pressure during C-section
This trial looks at whether we can predict which pregnant women will have a sudden drop in blood pressure during a cesarean section. If you're a healthy pregnant woman with a full-term single baby, this study could help improve safety.
KayseriAges 1.5 years–3.8 years - NCT07503522Recruiting
Personalized music and exercise for stroke recovery
This study tests whether adding personalized music to gentle aerobic exercise helps people recovering from a recent stroke improve faster. It's for patients in the early weeks or months after stroke who can sit, understand instructions, and don't have major heart or thinking problems.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07504276Recruiting
Remote rehab vs in-person rehab for stroke recovery
This study compares doing brain-training exercises at home on a digital device versus going to a clinic after a stroke. It aims to see which method better helps improve memory, thinking, and daily function.
Islamabad, Punjab ProvinceAges 50–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.